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Epidemiology of early life environmental risk factors for allergic sensitisation
1. Epidemiology of early life environmental
risk factors for allergic sensitisation
Group 1:
Hector Cuevas
Introduction
Rowan Heath
Elizabeth Morton Hector Cuevas
Stephanie Wagner
03 November 2011
2. Aim
• To provide an overview of the epidemiology of early life environmental
risk factors for allergic sensitisation
Learning Outcomes
By the end of the lecture you will:
– Understand the influence of environmental risk factors over the
prevalence for allergic diseases in the world
– Learn that there are many problems to stablish a proper
epidemiology for allergic sensitisation
– Know the importance of prevention and it’s promising impact on
allergic diseases
3. Epidemiology of early life environmental
risk factors for allergic sensitisation
Allergens /
Genes Irritants Microbes
Modified from a slide of Dr P S Noakes
“Early life origins of allergic disease”
4. Epidemiology of early life environmental
risk factors for allergic sensitisation
Allergens /
Genes Irritants Microbes
Modified from a slide of Dr P S Noakes
“Early life origins of allergic disease”
5. Epidemiology of early life environmental
risk factors for allergic sensitisation
Allergens /
Genes Irritants Microbes
Modified from a slide of Dr P S Noakes
“Early life origins of allergic disease”
6. International Study of Asthma and Allergies in
Childhood (ISAAC)
Anderson et al. Occup Environ Med 2010; 67(5): 293-300.
7. International Study of Asthma and Allergies in
Childhood (ISAAC)
c
>20%
10 to 20%
5 to 10%
<5%
Anderson et al. Occup Environ Med 2010; 67(5): 293-300.
8. International Study of Asthma and Allergies in
Childhood (ISAAC)
Anderson et al. Occup Environ Med 2010; 67(5): 293-300.
9. International Study of Asthma and Allergies in
Childhood (ISAAC)
Anderson et al. Occup Environ Med 2010; 67(5): 293-300.
10. Epidemiology of early life environmental
risk factors for allergic sensitisation
Genes Microbes Allergens /
Irritants
11. Genetics
Pearce N et als. Genetics, race, ethnicity and health. Br Med J 2004; 328: 1070-2
12. Epidemiology of early life environmental
risk factors for allergic sensitisation
Allergens /
Genes Irritants Microbes
13. Epidemiology of early life environmental
risk factors for allergic sensitisation
Allergens /
Genes Irritants Microbes