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Manufacturing
With more stringent waste regulations in place and
potential reclassifications forthcoming, along with
additional environmental and ‘cradle-to-grave’
pressures, the pharmaceutical industry is starting to focus
on emerging technologies to assist in the management of
its waste issues. One of the most promising of these
technologies is plasma gasification.
Plasma gasification uses extremely high temperatures,
generated by plasma torches, to break up organic and
inorganic waste streams; these are then turned into a
synthetic gas (syngas) or an obsidian-like vitrified matrix
that can be used in road construction as a concrete
aggregate or for other commercial purposes. The syngas
can be utilised to offset natural gas consumption in an
existing boiler, to generate steam/electricity or to
produce liquid fuels (ethanol). Metals in the feedstock
are reduced in the oxygen-starved environment of the
plasma reactor, and can be recovered as a mixture of
metals or as alloys. All feedstock represents 100 per cent
waste diversion, eliminating the need for landfills and/or
further processing.
At PEAT International, we manufacture a plasma-based
system called Plasma Thermal Destruction and
Recovery (PTDR); the technology is offered through
two system sizes suited for on-site applications – 130lbs
per hour/60kg per hour (the PTDR-100) and 550lbs
per hour/250kg per hour (the PTDR-500). The PTDR
technology has been deployed in installations in
Asia and the US and has received over ten permits
and certifications from environmental agencies across
the globe.
PLASMA THERMAL DESTRUCTION
AND RECOVERY
The patented PTDR technology uses heat generated by
plasma torches in an oxygen-starved, reducing
environment to first pull apart (dissociate) the
Plasma Thermal Destruction and Recovery (PTDR) technology enables
100 per cent diversion of pharmaceutical waste, eliminating the need
for landfill and/or further processing and generating synthetic gas
to offset energy consumption.
90 Innovations in Pharmaceutical Technology
By Jose Capote
and Daniel Ripes
at PEAT International
Energy-Efficient Management
of Pharma Waste
Waste PTDR
Syngas
Vitrified
product
Recovered
metals
Figure 1: Waste
processing using
PTDR technology
Electricity
Steam
Liquid fuels
Natural gas offset
Concrete aggregate
Roadbed/fill
Construction
Tiles
Metal
Refiner/recycled
molecules that make up the organic portions of the
waste; then – depending on the composition of the
waste stream – a controlled (stoichiometric) amount of
oxidant (either pure oxygen or steam) is added to
reform the dissociated elements of the waste into the
syngas, consisting mainly of carbon monoxide (CO)
and hydrogen (H2) (see Figure 1).
When waste is heated to a very high temperature in the
controlled atmosphere of the reducing plasma reactor, it
undergoes predictable physical and chemical changes.
This high temperature, over 1,000°C (1,800°F) prevents
the formation of complex organic molecules and breaks
down organics into a gas. These primary molecules are
stable above 965°C (1,770°F). The formation of dioxins
or furans is practically eliminated inside the plasma
reactor due to its process features, including high
uniform temperatures and a lack of excess oxygen within
the system.
This hot gas is then fed through a gas cleaning and
conditioning system. (The gas that comes out of a
plasma reactor has a trace of particulates, usually in the
form of unreacted carbon particles, compared with huge
quantities in an incinerator.) Here it is rapidly cooled
and cleaned to remove any entrained particulate and/or
acid gases prior to potential re-use.
Any inorganic constituents of the waste are melted
(vitrified) into an environmentally safe, leach resistant
glass matrix at the bottom of the basin within the
PTDR plasma reactor. The glass and metal layers are
removed through controllable tap ports into a glass
maxtrix/metal collection system. The taps are
connected to the slag handling system to allow
automated removal of the glass maxtrix upon operator
command. Removal of the molten glass requires no
special tools and does not disrupt the operating process.
The metal layer – below the molten glass – is tapped as
necessary, depending on the metal content of the
waste stream.
PTDR systems are driven by proprietary, state-of-the-art
instrumentation and computerised
control systems.
VALUABLE END PRODUCTS
GENERATED
The syngas has approximately one-
third to one-quarter of the heat value
of natural gas and can be utilised as a
substitute for fossil fuels (natural gas)
in boiler systems, an input for liquid fuel/steam
generation or utilised directly in gas engines to generate
electricity. As the cost of natural gas fluctuates, the
economic benefits associated with the use of waste-
generated syngas become more valuable.
At one PTDR-100 system being installed in the western
part of the US, we are integrating a gas engine designed
to operate on the syngas. Based on this successful
deployment, we intend to offer future commercial
PTDR-100 systems with the option of utilising an
integrated 50-kWe engine. The integration of such a
feature would provide approximately two-thirds of the
electricity for the system when processing
pharmaceutical waste. It is worth noting that some utility
consumption rates – including electricity – vary
depending on the waste feedstock being processed. Also,
PTDR systems generally result in a net reduction of
greenhouse gases, and thus carbon credits may also be
generated.
For PTDR-500 systems, our current projects have called
for the syngas to be utilised in a number of different
ways: to generate steam or to offset the use of fossil fuels
in an existing boiler, as well as the production of electric
power. We are in the process of undertaking the
development work to integrate a larger gas engine
(around 250kWe) to directly generate electricity in a
similar fashion to the PTDR-100 system.
With PTDR-500 systems, the syngas can also be used as
a fuel source in a simple steam-cycle configuration (using
the syngas in a conventional boiler/steam generator and
then using the steam in a conventional steam turbine to
produce electric power). The electric power produced
(approximately 210KWe from a steam cycle or
approximately 250KWe from a gas engine) would offset
the system’s electricity consumption (approximately
180KWe), thereby generating excess power that would
be available for sale.
The vitrified product can be used in a variety of
commercial applications including concrete aggregate,
91Innovations in Pharmaceutical Technology
System Average Application Sales price O&M cost Number of base Syngas generation Estimated
capacity range operators required (BTU/hr) ** payback period
PTDR-100 60kg On-site ~$1,000,000 US$0.58/kg 1 1,250,000 Less than
(130lbs)/hr ($0.20/lb) two years
PTDR-500 350kg On-site ~$4,000,000 US$0.30/kg 2 4,500,000 Less than
(770lbs)/hrUS centralised ($0.14/lb) one year
* US market assumed; however, this could be reduced in other countries as labour and electricity rates fluctuate
according to market. Also includes offset of natural gas at $7 per MMBTU
** Assumes pharmaceutical-based waste stream
Figure 2: Financial overview of the PDTR-100 and -500 systems
insulation and roadbed construction. The metal layer can
contain relatively pure amounts of iron, copper and
aluminium.
The composition of end products varies on the basis
of waste composition. Processing pharmaceutical
waste, with high percentages of carbon, produces
meaningful levels of syngas, and lesser amounts of the
vitrified matrix. Conversely, processing e-wastes or
light bulbs produces lower amounts of syngas and
relatively more vitrified product and recovered metal
alloys.
Economics and Operations
With regard to operations and variable costs, PTDR-
100 or -500 systems require labour, electricity, water,
caustic for the gas cleaning and conditioning system,
and plasma electrodes. The wastewater discharge – less
than three per cent salt – is safe enough to release into
any local sewer.
The automated process control system allows PTDR
systems to be operated by a single trained operator. One
auxiliary employee (two for the PTDR-500) may be
required to assist with materials handling (waste
receiving/feeding and end-product collection).
Ultimately the commercial success of the PTDR
technology lies in its ability to generate a favourable net-
present value based on existing market prices, industry
dynamics and metrics. Using a conservative price point
for pharmaceutical waste at $0.50 per pound, important
financial benefits can be seen. Both PTDR systems have
the ability to process feedstock on a continuous basis,
feeding 21 hours a day with three hours reserved for
maintenance and inorganic vitrification/pre-heating.
Using 340 days per year, this indicates 8,165 operational
hours per year. The chart in Figure 2 provides a financial
overview
PTDR 100 and 500 systems are provided on a
turnkey/joint-venture basis and are sized to
accommodate large industrial manufacturing facilities to
mid-size regional hospitals.
NEW CHALLENGES REQUIRE
INNOVATIVE SOLUTIONS
The two dominant waste treatment solutions –
incineration and landfill – continue to fall out of favour
with regulators and the general public for a myriad of
reasons: pollution, advancing regulations, minimal
recycling, and so on. However, as climate change
challenges increase and waste continues to be generated,
alternative solutions are gaining traction.
With stringent regulations in place and new ones always
being introduced, waste industries throughout the world
are focused on newer technologies that improve the
process of managing pharmaceutical waste. In addition
to being environmentally friendly, PTDR systems can
process inorganic and organic feedstocks together, thus
minimising or even eliminating any pre-processing or
staging costs. Further, wastes with little or no calorific
value can be effectively treated.
Finally, unlike incineration or metal-bearing waste
stabilisation, the PTDR process does not create any
secondary solid wastes that would require further
treatment or landfilling. For example, incinerators
produce large quantities of bottom and fly ash that are
toxic in nature and require further treatment (with
stabilisation agents); the resulting post-treated materials
(whose volume may have increased significantly) will
also require final disposal, sometimes in specially
designed hazardous waste landfills. With a PTDR
system, all feedstock represents 100 per cent waste
92 Innovations in Pharmaceutical Technology
Figure 3: PTDR-100
system commissioned
to process a wide range
of solid waste streams,
including medical waste,
industrial process waste
(organic and inorganic)
and pharmaceutical
industry waste
The two dominant waste treatment
solutions – incineration and landfill –
continue to fall out of favour with
regulators and the general public for a
myriad of reasons: pollution, advancing
regulations, minimal recycling, and so on.
However, as climate change challenges
increase and waste continues to be
generated, alternative solutions are
gaining traction.
diversion, which eliminates the need for landfill disposal
and/or further processing.
INSTALLATIONS AND
GOVERNMENT APPROVALS
One research and development facility and four proof-
of-concept facilities have been constructed to date. An
R&D facility in Huntsville, Alabama, built in the
1990s and operated until 2003, successfully
completed numerous campaigns on a wide range of
waste streams, including hazardous/toxic, medical and
infectious, and military. As to the proof-of-concept
facilities, in 2000 PEAT Inc (the predecessor to PEAT
International, Inc) constructed a 350kg/hour
(770lbs/hour) facility in Lorton, Virginia, for use by
the US Army to treat agriculture blast media and
regulated medical waste.
At the National Cheng Kung University in Taiwan, we
completed the construction of a 200 kg/hour (440
lbs/hr) system to process incinerator fly ash, medical and
hazardous waste in January 2005. In early 2007, we
finished work on a 20kg/hr (45lbs/hr) system at Fooyin
University (Southern Taiwan), that has applications for
mobile system deployment. In February 2008, we
commissioned a PTDR-100 system to process a wide
range of solid waste streams, including medical waste,
industrial process waste (organic and inorganic) and
pharmaceutical industry waste (see Figure 3).
At present, we are installing our first PTDR-100 in the
US; this is scheduled to be operating early in the second
quarter of 2009. The PTDR technology has already
received numerous approvals from regulatory authorities
throughout the globe, including:
N Taiwanese Environmental Protection Agency
N Taiwan Ministry of Education
N Kaohsiung Department of Environmental
Protection
N Virginia Department of Environmental Quality
N Alabama Department of Environmental
Management
N City of Huntsville Natural Resources Division
N San Diego Air Pollution Control District
N Indiana Department of Environmental
Management
N Michigan Department of Environmental
Quality
N California Department of Public Health
Waste treatment and alternative energy generation are
two of the most difficult challenges facing many
industries today. An ever-increasing global output,
coupled with the rapid industrialisation seen in many
developing countries, is forcing the world to not only
rethink how it handles waste, but how it views waste as
a resource. Plasma gasification – and specifically the
PTDR technology – allows companies to do just that.
94 Innovations in Pharmaceutical Technology
Jose Capote is Chief Technical Officer PEAT International.
He has over 20 years’ experience in engineering, project
development and project management, in the
environmental, nuclear and conventional energy, and
industrial sectors. As senior executive with several US
companies, Jose was involved in a wide range of energy,
environmental, waste management and energy projects.
In his varied assignments, he was responsible for projects involving
‘Superfund ‘clean-ups, facility de-commissioning and re-industrialisations,
and waste-to-energy and conventional energy production projects. Jose
graduated from Columbia University (New York, NY) with a degree in
Nuclear Engineering. Email: ???
Daniel Ripes is Corporate Finance and Business
Development Manager at PEAT International. Prior to
joining PEAT, was the Corporate Communications
Manager for CGI International, where his responsibilities
included the coordination of all corporate communication
aspects for a pre-IPO/public company. Daniel holds a
Bachelors of Arts Degree in Communications from the
University of Illinois Urbana-Champaign, and is a Masters of Business
Administration Candidate at the University of Illinois-Chicago, Liautaud
School of Business. Email: ???
Figure 4: Plasma
torch in operation

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Ipt peat-april09

  • 1. Manufacturing With more stringent waste regulations in place and potential reclassifications forthcoming, along with additional environmental and ‘cradle-to-grave’ pressures, the pharmaceutical industry is starting to focus on emerging technologies to assist in the management of its waste issues. One of the most promising of these technologies is plasma gasification. Plasma gasification uses extremely high temperatures, generated by plasma torches, to break up organic and inorganic waste streams; these are then turned into a synthetic gas (syngas) or an obsidian-like vitrified matrix that can be used in road construction as a concrete aggregate or for other commercial purposes. The syngas can be utilised to offset natural gas consumption in an existing boiler, to generate steam/electricity or to produce liquid fuels (ethanol). Metals in the feedstock are reduced in the oxygen-starved environment of the plasma reactor, and can be recovered as a mixture of metals or as alloys. All feedstock represents 100 per cent waste diversion, eliminating the need for landfills and/or further processing. At PEAT International, we manufacture a plasma-based system called Plasma Thermal Destruction and Recovery (PTDR); the technology is offered through two system sizes suited for on-site applications – 130lbs per hour/60kg per hour (the PTDR-100) and 550lbs per hour/250kg per hour (the PTDR-500). The PTDR technology has been deployed in installations in Asia and the US and has received over ten permits and certifications from environmental agencies across the globe. PLASMA THERMAL DESTRUCTION AND RECOVERY The patented PTDR technology uses heat generated by plasma torches in an oxygen-starved, reducing environment to first pull apart (dissociate) the Plasma Thermal Destruction and Recovery (PTDR) technology enables 100 per cent diversion of pharmaceutical waste, eliminating the need for landfill and/or further processing and generating synthetic gas to offset energy consumption. 90 Innovations in Pharmaceutical Technology By Jose Capote and Daniel Ripes at PEAT International Energy-Efficient Management of Pharma Waste Waste PTDR Syngas Vitrified product Recovered metals Figure 1: Waste processing using PTDR technology Electricity Steam Liquid fuels Natural gas offset Concrete aggregate Roadbed/fill Construction Tiles Metal Refiner/recycled
  • 2. molecules that make up the organic portions of the waste; then – depending on the composition of the waste stream – a controlled (stoichiometric) amount of oxidant (either pure oxygen or steam) is added to reform the dissociated elements of the waste into the syngas, consisting mainly of carbon monoxide (CO) and hydrogen (H2) (see Figure 1). When waste is heated to a very high temperature in the controlled atmosphere of the reducing plasma reactor, it undergoes predictable physical and chemical changes. This high temperature, over 1,000°C (1,800°F) prevents the formation of complex organic molecules and breaks down organics into a gas. These primary molecules are stable above 965°C (1,770°F). The formation of dioxins or furans is practically eliminated inside the plasma reactor due to its process features, including high uniform temperatures and a lack of excess oxygen within the system. This hot gas is then fed through a gas cleaning and conditioning system. (The gas that comes out of a plasma reactor has a trace of particulates, usually in the form of unreacted carbon particles, compared with huge quantities in an incinerator.) Here it is rapidly cooled and cleaned to remove any entrained particulate and/or acid gases prior to potential re-use. Any inorganic constituents of the waste are melted (vitrified) into an environmentally safe, leach resistant glass matrix at the bottom of the basin within the PTDR plasma reactor. The glass and metal layers are removed through controllable tap ports into a glass maxtrix/metal collection system. The taps are connected to the slag handling system to allow automated removal of the glass maxtrix upon operator command. Removal of the molten glass requires no special tools and does not disrupt the operating process. The metal layer – below the molten glass – is tapped as necessary, depending on the metal content of the waste stream. PTDR systems are driven by proprietary, state-of-the-art instrumentation and computerised control systems. VALUABLE END PRODUCTS GENERATED The syngas has approximately one- third to one-quarter of the heat value of natural gas and can be utilised as a substitute for fossil fuels (natural gas) in boiler systems, an input for liquid fuel/steam generation or utilised directly in gas engines to generate electricity. As the cost of natural gas fluctuates, the economic benefits associated with the use of waste- generated syngas become more valuable. At one PTDR-100 system being installed in the western part of the US, we are integrating a gas engine designed to operate on the syngas. Based on this successful deployment, we intend to offer future commercial PTDR-100 systems with the option of utilising an integrated 50-kWe engine. The integration of such a feature would provide approximately two-thirds of the electricity for the system when processing pharmaceutical waste. It is worth noting that some utility consumption rates – including electricity – vary depending on the waste feedstock being processed. Also, PTDR systems generally result in a net reduction of greenhouse gases, and thus carbon credits may also be generated. For PTDR-500 systems, our current projects have called for the syngas to be utilised in a number of different ways: to generate steam or to offset the use of fossil fuels in an existing boiler, as well as the production of electric power. We are in the process of undertaking the development work to integrate a larger gas engine (around 250kWe) to directly generate electricity in a similar fashion to the PTDR-100 system. With PTDR-500 systems, the syngas can also be used as a fuel source in a simple steam-cycle configuration (using the syngas in a conventional boiler/steam generator and then using the steam in a conventional steam turbine to produce electric power). The electric power produced (approximately 210KWe from a steam cycle or approximately 250KWe from a gas engine) would offset the system’s electricity consumption (approximately 180KWe), thereby generating excess power that would be available for sale. The vitrified product can be used in a variety of commercial applications including concrete aggregate, 91Innovations in Pharmaceutical Technology System Average Application Sales price O&M cost Number of base Syngas generation Estimated capacity range operators required (BTU/hr) ** payback period PTDR-100 60kg On-site ~$1,000,000 US$0.58/kg 1 1,250,000 Less than (130lbs)/hr ($0.20/lb) two years PTDR-500 350kg On-site ~$4,000,000 US$0.30/kg 2 4,500,000 Less than (770lbs)/hrUS centralised ($0.14/lb) one year * US market assumed; however, this could be reduced in other countries as labour and electricity rates fluctuate according to market. Also includes offset of natural gas at $7 per MMBTU ** Assumes pharmaceutical-based waste stream Figure 2: Financial overview of the PDTR-100 and -500 systems
  • 3. insulation and roadbed construction. The metal layer can contain relatively pure amounts of iron, copper and aluminium. The composition of end products varies on the basis of waste composition. Processing pharmaceutical waste, with high percentages of carbon, produces meaningful levels of syngas, and lesser amounts of the vitrified matrix. Conversely, processing e-wastes or light bulbs produces lower amounts of syngas and relatively more vitrified product and recovered metal alloys. Economics and Operations With regard to operations and variable costs, PTDR- 100 or -500 systems require labour, electricity, water, caustic for the gas cleaning and conditioning system, and plasma electrodes. The wastewater discharge – less than three per cent salt – is safe enough to release into any local sewer. The automated process control system allows PTDR systems to be operated by a single trained operator. One auxiliary employee (two for the PTDR-500) may be required to assist with materials handling (waste receiving/feeding and end-product collection). Ultimately the commercial success of the PTDR technology lies in its ability to generate a favourable net- present value based on existing market prices, industry dynamics and metrics. Using a conservative price point for pharmaceutical waste at $0.50 per pound, important financial benefits can be seen. Both PTDR systems have the ability to process feedstock on a continuous basis, feeding 21 hours a day with three hours reserved for maintenance and inorganic vitrification/pre-heating. Using 340 days per year, this indicates 8,165 operational hours per year. The chart in Figure 2 provides a financial overview PTDR 100 and 500 systems are provided on a turnkey/joint-venture basis and are sized to accommodate large industrial manufacturing facilities to mid-size regional hospitals. NEW CHALLENGES REQUIRE INNOVATIVE SOLUTIONS The two dominant waste treatment solutions – incineration and landfill – continue to fall out of favour with regulators and the general public for a myriad of reasons: pollution, advancing regulations, minimal recycling, and so on. However, as climate change challenges increase and waste continues to be generated, alternative solutions are gaining traction. With stringent regulations in place and new ones always being introduced, waste industries throughout the world are focused on newer technologies that improve the process of managing pharmaceutical waste. In addition to being environmentally friendly, PTDR systems can process inorganic and organic feedstocks together, thus minimising or even eliminating any pre-processing or staging costs. Further, wastes with little or no calorific value can be effectively treated. Finally, unlike incineration or metal-bearing waste stabilisation, the PTDR process does not create any secondary solid wastes that would require further treatment or landfilling. For example, incinerators produce large quantities of bottom and fly ash that are toxic in nature and require further treatment (with stabilisation agents); the resulting post-treated materials (whose volume may have increased significantly) will also require final disposal, sometimes in specially designed hazardous waste landfills. With a PTDR system, all feedstock represents 100 per cent waste 92 Innovations in Pharmaceutical Technology Figure 3: PTDR-100 system commissioned to process a wide range of solid waste streams, including medical waste, industrial process waste (organic and inorganic) and pharmaceutical industry waste The two dominant waste treatment solutions – incineration and landfill – continue to fall out of favour with regulators and the general public for a myriad of reasons: pollution, advancing regulations, minimal recycling, and so on. However, as climate change challenges increase and waste continues to be generated, alternative solutions are gaining traction.
  • 4. diversion, which eliminates the need for landfill disposal and/or further processing. INSTALLATIONS AND GOVERNMENT APPROVALS One research and development facility and four proof- of-concept facilities have been constructed to date. An R&D facility in Huntsville, Alabama, built in the 1990s and operated until 2003, successfully completed numerous campaigns on a wide range of waste streams, including hazardous/toxic, medical and infectious, and military. As to the proof-of-concept facilities, in 2000 PEAT Inc (the predecessor to PEAT International, Inc) constructed a 350kg/hour (770lbs/hour) facility in Lorton, Virginia, for use by the US Army to treat agriculture blast media and regulated medical waste. At the National Cheng Kung University in Taiwan, we completed the construction of a 200 kg/hour (440 lbs/hr) system to process incinerator fly ash, medical and hazardous waste in January 2005. In early 2007, we finished work on a 20kg/hr (45lbs/hr) system at Fooyin University (Southern Taiwan), that has applications for mobile system deployment. In February 2008, we commissioned a PTDR-100 system to process a wide range of solid waste streams, including medical waste, industrial process waste (organic and inorganic) and pharmaceutical industry waste (see Figure 3). At present, we are installing our first PTDR-100 in the US; this is scheduled to be operating early in the second quarter of 2009. The PTDR technology has already received numerous approvals from regulatory authorities throughout the globe, including: N Taiwanese Environmental Protection Agency N Taiwan Ministry of Education N Kaohsiung Department of Environmental Protection N Virginia Department of Environmental Quality N Alabama Department of Environmental Management N City of Huntsville Natural Resources Division N San Diego Air Pollution Control District N Indiana Department of Environmental Management N Michigan Department of Environmental Quality N California Department of Public Health Waste treatment and alternative energy generation are two of the most difficult challenges facing many industries today. An ever-increasing global output, coupled with the rapid industrialisation seen in many developing countries, is forcing the world to not only rethink how it handles waste, but how it views waste as a resource. Plasma gasification – and specifically the PTDR technology – allows companies to do just that. 94 Innovations in Pharmaceutical Technology Jose Capote is Chief Technical Officer PEAT International. He has over 20 years’ experience in engineering, project development and project management, in the environmental, nuclear and conventional energy, and industrial sectors. As senior executive with several US companies, Jose was involved in a wide range of energy, environmental, waste management and energy projects. In his varied assignments, he was responsible for projects involving ‘Superfund ‘clean-ups, facility de-commissioning and re-industrialisations, and waste-to-energy and conventional energy production projects. Jose graduated from Columbia University (New York, NY) with a degree in Nuclear Engineering. Email: ??? Daniel Ripes is Corporate Finance and Business Development Manager at PEAT International. Prior to joining PEAT, was the Corporate Communications Manager for CGI International, where his responsibilities included the coordination of all corporate communication aspects for a pre-IPO/public company. Daniel holds a Bachelors of Arts Degree in Communications from the University of Illinois Urbana-Champaign, and is a Masters of Business Administration Candidate at the University of Illinois-Chicago, Liautaud School of Business. Email: ??? Figure 4: Plasma torch in operation