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Jean-Marc Huët
Senior Vice President and
 Chief Financial Officer

Credit Suisse Health Care Conference
          November 13, 2008


           Not For Promotional Use
13 November 2008

During this meeting, we will make statements about the Company’s future
plans and prospects, including statements about our financial position,
business strategy, research pipeline concerning product development and
product potential, that constitute forward-looking statements for purposes
of the safe harbor provisions under the Private Securities Litigation Reform
Act of 1995.
Actual results may differ materially from those indicated by these forward-
looking statements as a result of various important factors, including those
discussed in the company’s most recent annual report on Form 10-K,
periodic reports on Form 10-Q and current reports on Form 8-K. These
documents are available from the SEC, the Bristol-Myers Squibb website
or from Bristol-Myers Squibb Investor Relations.
In addition, any forward-looking statements represent our estimates only as
of today and should not be relied upon as representing our estimates as of
any subsequent date. While we may elect to update forward-looking
statements at some point in the future, we specifically disclaim any
obligation to do so, even if our estimates change.

                             Not For Promotional Use
Next Generation BioPharma Leader

                                  Best of Pharma
           Best of Biotech


                  Next Generation
                    BioPharma



   Innovate             Integrate                  Improve


   Agile, Entrepreneurial and Accountable Culture

                   Not For Promotional Use
                                                             3
2008 Highlights

   Important steps taken to become a
   Next Generation BioPharma Company

   Very strong operating performance

   Strengthened overall financial position

   Increased focus on longer term sustainability



                  Not For Promotional Use
                                                   4
Significant Shifts in BMY Portfolio
         Medical Imaging
          – Sold for ~ $500 million
         ConvaTec
          – Sold for ~ $4.1 billion
         Mead Johnson
          – Planned 10-20% IPO
         Adnexus
          – Purchased for ~ $500 million
         Kosan
          – Purchased for ~ $200 million

                  Not For Promotional Use
                                            5
A More Focused Portfolio Today

        January 2007                                      September 2008
                                  Pharmaceuticals
                                                                86%
                    77%
                                   Mead Johnson
                          13%                             14%


                           6%
                          4%
                                     ConvaTec
                                 Medical Imaging




Based on Revenues
                                Not For Promotional Use
                                                                           6
Strong Sept YTD Operating Performance

           Strong, Broad-based and High-Quality Sales Growth
            – Global Sales                     17%
            – Volume Growth                    9%

           Improved Non-GAAP Margins*
            – Gross Margin                     90 basis points
            – Net Margin                       210 basis points

           Robust Non-GAAP EPS Growth*                           32%


* GAAP to Non-GAAP reconciliations available on BMS website.

                                      Not For Promotional Use
                                                                       7
Broad-based Sept YTD Sales Growth

  Business Segment                                   Geographic Area
                                                                         +17%
                           +14%
                                                               U.S.
                      Mead
                     Johnson

                                                 Lat Can
   Pharmaceuticals
                                                     Pacific
                                       +8%                       EMEA


+17%                                         +19%
                                                                        +18%

                           Not For Promotional Use
                                                                                8
Important Productivity Initiatives
Are Underway

                                                  Commercial
         Supply Chain          R&D                                    G&A
Wave 1                                             Operations
           $400 MM           $200 MM                                $350 MM
                                                    $550 MM

                                = $1.5 Billion


               Headcount &                                 Streamlining
Wave 2                              Procurement
               Related Costs                               Organization

                                = $1 Billion
                        Not For Promotional Use
                                                                              9
Strong Financial Position




        Not For Promotional Use
BMY Has a Very Strong Cash Position

                                                                  2009 FCF*
                          $7.2 Bn                       MJN*
                                        Imclone*




           $1.8 Bn




           Cash         Cash                                                      Cash
        31 Dec 2007 30 Sept 2008                                              31 Dec 2009**
 * Expected future cash flows
** Expected cash excluding business development
                                        Not For Promotional Use
                                                                                              11
BMY Has a Conservative Capital Structure

                                         31 Dec 2007   30 Sept 2008
Cash, Marketable Securities                 $2.2 Bn      $7.4 Bn

 % Treasuries / Treasury backed                   —       84%

Debt                                        $6.3 Bn      $6.3 Bn

 Average Maturity                            16 yrs       21 yrs

Net (Debt) / Cash                          ($4.1) Bn     $1.2 Bn




                        Not For Promotional Use
                                                                      12
We Have Increased Our Focus on Cash Flow
       Earnings
        – Sales growth
        – Productivity initiatives
       Capital expenditures
        – Manufacturing rationalization
        – Devens
       Changes in trade working capital
        – Receivables
        – Inventory
        – Payables
                 Not For Promotional Use
                                           13
There Is Significant Scope for Improvement
    Working Capital as % of Sales – 12/31/2007




                          21%
                                             17%
                                                                 12%


                Pharma Average*              BMY             Best in Class*


* Bristol-Myers Squibb estimates
                                   Not For Promotional Use
                                                                              14
We Have Started a Working Capital Initiative

   Receivables                                       Payables
                          Inventory
• Process float                                • Compliance to terms
                     • Forecast accuracy
• Commercial terms                             • Extension of terms
                     • Plant and SKU
                       rationalization




     Goal: Improve cash flows by $750 MM to $1 BN
    through improvements in working capital by 2011

                     Not For Promotional Use
                                                                       15
Looking at the Business in Three Stages
                                   1                          2                       3
                      Execution                          Execution &        Promise of
                                                         Productivity       BioPharma Model
                      Productivity
                                                         Pipeline           Pipeline
Pre-Tax Earnings




                      Investment in Stage 2 & 3
                                                         Business           Business Development
                                                         Development




                          Current Growth                  Base                    Return to
                            Trajectory                   Earnings                  Growth

                   2007                             2011             2013                          2017
                                                  Not For Promotional Use
                                                                                                          16
Initial Impressions

    Organizational passion and talent

    An incredibly resilient organization

    The need to achieve the right balance
    as we move forward

    The need to leverage the advantage of our
    mid size and scale

    Significant accomplishments in 2008


                  Not For Promotional Use
                                                17
Jean-Marc Huët
Senior Vice President and
 Chief Financial Officer

Credit Suisse Health Care Conference
          November 13, 2008


           Not For Promotional Use

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BMY CFO Discusses 2008 Performance and Future Plans

  • 1. Jean-Marc Huët Senior Vice President and Chief Financial Officer Credit Suisse Health Care Conference November 13, 2008 Not For Promotional Use
  • 2. 13 November 2008 During this meeting, we will make statements about the Company’s future plans and prospects, including statements about our financial position, business strategy, research pipeline concerning product development and product potential, that constitute forward-looking statements for purposes of the safe harbor provisions under the Private Securities Litigation Reform Act of 1995. Actual results may differ materially from those indicated by these forward- looking statements as a result of various important factors, including those discussed in the company’s most recent annual report on Form 10-K, periodic reports on Form 10-Q and current reports on Form 8-K. These documents are available from the SEC, the Bristol-Myers Squibb website or from Bristol-Myers Squibb Investor Relations. In addition, any forward-looking statements represent our estimates only as of today and should not be relied upon as representing our estimates as of any subsequent date. While we may elect to update forward-looking statements at some point in the future, we specifically disclaim any obligation to do so, even if our estimates change. Not For Promotional Use
  • 3. Next Generation BioPharma Leader Best of Pharma Best of Biotech Next Generation BioPharma Innovate Integrate Improve Agile, Entrepreneurial and Accountable Culture Not For Promotional Use 3
  • 4. 2008 Highlights Important steps taken to become a Next Generation BioPharma Company Very strong operating performance Strengthened overall financial position Increased focus on longer term sustainability Not For Promotional Use 4
  • 5. Significant Shifts in BMY Portfolio Medical Imaging – Sold for ~ $500 million ConvaTec – Sold for ~ $4.1 billion Mead Johnson – Planned 10-20% IPO Adnexus – Purchased for ~ $500 million Kosan – Purchased for ~ $200 million Not For Promotional Use 5
  • 6. A More Focused Portfolio Today January 2007 September 2008 Pharmaceuticals 86% 77% Mead Johnson 13% 14% 6% 4% ConvaTec Medical Imaging Based on Revenues Not For Promotional Use 6
  • 7. Strong Sept YTD Operating Performance Strong, Broad-based and High-Quality Sales Growth – Global Sales 17% – Volume Growth 9% Improved Non-GAAP Margins* – Gross Margin 90 basis points – Net Margin 210 basis points Robust Non-GAAP EPS Growth* 32% * GAAP to Non-GAAP reconciliations available on BMS website. Not For Promotional Use 7
  • 8. Broad-based Sept YTD Sales Growth Business Segment Geographic Area +17% +14% U.S. Mead Johnson Lat Can Pharmaceuticals Pacific +8% EMEA +17% +19% +18% Not For Promotional Use 8
  • 9. Important Productivity Initiatives Are Underway Commercial Supply Chain R&D G&A Wave 1 Operations $400 MM $200 MM $350 MM $550 MM = $1.5 Billion Headcount & Streamlining Wave 2 Procurement Related Costs Organization = $1 Billion Not For Promotional Use 9
  • 10. Strong Financial Position Not For Promotional Use
  • 11. BMY Has a Very Strong Cash Position 2009 FCF* $7.2 Bn MJN* Imclone* $1.8 Bn Cash Cash Cash 31 Dec 2007 30 Sept 2008 31 Dec 2009** * Expected future cash flows ** Expected cash excluding business development Not For Promotional Use 11
  • 12. BMY Has a Conservative Capital Structure 31 Dec 2007 30 Sept 2008 Cash, Marketable Securities $2.2 Bn $7.4 Bn % Treasuries / Treasury backed — 84% Debt $6.3 Bn $6.3 Bn Average Maturity 16 yrs 21 yrs Net (Debt) / Cash ($4.1) Bn $1.2 Bn Not For Promotional Use 12
  • 13. We Have Increased Our Focus on Cash Flow Earnings – Sales growth – Productivity initiatives Capital expenditures – Manufacturing rationalization – Devens Changes in trade working capital – Receivables – Inventory – Payables Not For Promotional Use 13
  • 14. There Is Significant Scope for Improvement Working Capital as % of Sales – 12/31/2007 21% 17% 12% Pharma Average* BMY Best in Class* * Bristol-Myers Squibb estimates Not For Promotional Use 14
  • 15. We Have Started a Working Capital Initiative Receivables Payables Inventory • Process float • Compliance to terms • Forecast accuracy • Commercial terms • Extension of terms • Plant and SKU rationalization Goal: Improve cash flows by $750 MM to $1 BN through improvements in working capital by 2011 Not For Promotional Use 15
  • 16. Looking at the Business in Three Stages 1 2 3 Execution Execution & Promise of Productivity BioPharma Model Productivity Pipeline Pipeline Pre-Tax Earnings Investment in Stage 2 & 3 Business Business Development Development Current Growth Base Return to Trajectory Earnings Growth 2007 2011 2013 2017 Not For Promotional Use 16
  • 17. Initial Impressions Organizational passion and talent An incredibly resilient organization The need to achieve the right balance as we move forward The need to leverage the advantage of our mid size and scale Significant accomplishments in 2008 Not For Promotional Use 17
  • 18. Jean-Marc Huët Senior Vice President and Chief Financial Officer Credit Suisse Health Care Conference November 13, 2008 Not For Promotional Use