This document discusses antiemetic and antinausea agents used to treat nausea and vomiting. It describes the vomiting center and chemoreceptor trigger zone in the brain that stimulate vomiting when activated. Various classes of antiemetics work by blocking pathways in these areas, including anticholinergic, antihistamine, neuroleptic, prokinetic, serotonin blocking, and tetrahydrocannabinoid agents. Common side effects stem from the nonselective blockade of various receptors. Nursing implications include assessing nausea history, monitoring for therapeutic and adverse effects, and warning patients about risks of drowsiness or hypotension.

1. CHAPTER 51 Antiemetic and Antinausea Agents