Davis aas 2012 goddard 1

50th Robert H. Goddard Memorial
Symposium
Dreams and Possibilities: Planning for the
Achievable

Human Exploration Strategy – Extend and
Sustain Human Activities Across the Solar
System
March 28, 2012
Jeffrey R. Davis, MD
Director, Space Life Sciences, NASA
Space Life Sciences
Exploring Space |Enhancing Life

Strategic Initiatives

• 2007 SLSD Strategic Plan

– Mission Statement
“To optimize human health and productivity for space exploration“
– Vision Statement
"To become the recognized world leader in human
health, performance and productivity for space exploration”
– Strategic Goals
o Manage balanced internal/external portfolio
o Drive health innovations
o Drive human system integration innovations
o Educate and inspire
Space Life Sciences
2 2

Strategic Initiatives

• Summary
• Visioning exercise and strategic plan
• Alliances benchmark 2008-2010
• HBS collaborative innovation models and
collaborative projects 2008-2010
• Open innovation pilot project 2008-2010
• Virtual center for collaboration established
2010: NASA Human Health and Performance
center
• Pursue collaborative research models 2011
• Develop Strategic Framework for Innovation
2011 Space Life Sciences
3

Portfolio Definition

• Human System risks for space flight (our portfolio of work)
• Evidence based risk management system
• 65 human system risks
• Human System Risk Board formed April 2008 –integrates
research and operations—decisions made by one entity

• Developed Risk Management Analysis Tool (RMAT)
• Captures vertical “standards to deliverables” process
• Links risks for common elements

• Subject matter experts (risk owners) identify gaps in their
research and technology portfolio

• Gaps became opportunities for open collaborative solutions
Space Life Sciences
4

Portfolio Analysis

• Portfolio mapping – Dr. Gary Pisano, Harvard
Business School (HBS)
• “Which Kind of Collaboration is Right for You” – Harvard
Business Review, December 2008

• Workshop conducted by Dr. Pisano with NASA – Wyle
leadership team July 2009
• Analyzed 12 gaps for collaborative opportunity, those
that mapped to open innovation quadrant selected for
pilot projects

Space Life Sciences
5

Portfolio Analysis: Mapping -
Models of Collaboration

From Gary Pisano, Harvard Business School
Space Life Sciences
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Internal innovation – “elite circle”

• Internal innovation projects

• Procure and adapt – retinal camera example

• New development – intravenous fluid from potable water

• Modified technology – colorimetric water analysis
(formerly a device to evaluate paint color)

• Air quality – adapt a commercial device for another
purpose

Space Life Sciences
7

Remote Eye Imaging
Discovery of changes in eyes Preflight Postflight
prompted the need for remote eye
imaging on ISS as soon as possible

Found solution from a
Wisconsin Optometrist who had
invented a remote camera for an
ophthalmoscope for use with his
patients on remote islands

New scope was flown within
weeks and successfully began
monitoring changes in the eye.

Space Life Sciences

Colorimetric Water Quality Monitoring Kit (CWQMK)

CWQMK utilizes Colorimetric Solid Phase Extraction (CSPE) technology to
protect crew health by providing the capability to perform in-flight
measurements of iodine and silver levels in spacecraft potable water systems

• Silver(I) and iodine are biocides in spacecraft drinking water storage and distribution
systems
• U.S. Water Recovery System uses Iodine
o Low iodine levels allow microbial growth
o Long term consumption of high I2 levels can cause thyroid dysfunction
• ISS Russian segment uses Silver (Ag+)
o Long-term consumption of high silver levels can cause Argyria (irreversible blue-
gray discoloration of the skin)
• Current biocide monitoring approach relies on archive samples which are collected in-
flight, stored, then returned to ground and analyzed at JSC. Issues:
o Techniques and/or hardware not in-flight deployable
o Biocide levels subject to sample degradation during storage and transport

Hardware Description
• Solution is a simple, compact, hand-held device that reliably and rapidly measures key
water quality indicators in-flight
• Water sample is passed through membrane cartridge resulting in color change on
membrane surface in the presence of silver or iodine
• Commercially available Diffuse Reflectance Spectrophotometer (DRS) measures
magnitude of color change, which is proportional to the amount of analyte present in
sample volume
Space Life Sciences
• CSPE water quality monitoring kit was delivered to ISS on STS 128/17A 9

Exploration Medical Capability
IntraVenous fluid GENeration for exploration (IVGEN)

PRODUCE USP GRADE 0.9% NORMAL SALINE FROM IN
SITU RESOURCES

• IV fluid required to respond to medical
contingencies

• Filter to generate fluid incurs a smaller mass
and volume cost than the actual fluid

• System based on deionization and sterilizing
filters

FLIGHT TEST: MAY 4-7, 2010
Space Life Sciences
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10

Open Innovation
• Open innovation and collaboration– four pilot projects

• InnoCentive- posts individual challenges/gaps to their established
network of solvers (~300,000)
• financial award if the solution is found viable by the posting entity

• Yet2.com- acts as an actual technology scout bringing together buyers and
sellers of technologies
• Option to develop partnerships

• TopCoder - open innovation software company with a large network of
solvers (~300,000)
• variety of skill-based software coding competitions

• NASA@work-internal collaboration platform leveraging expertise found
across NASA’s 10 centers

Space Life Sciences
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INNOCENTIVE

Space Life Sciences
12

NASA Pavilion on InnoCentive

Global Appeal-

2900 solvers
80 Countries
Space Life Sciences
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InnoCentive Pilot Results
Proj Award Award
Challenge Title Ctr Posted Deadline Sub
Rms Date Amount
Improved Barrier Layers … JSC -
12/18/2009 2/28/2010 174 22 5/7/2010 $11,000
Keeping Food Fresh in Space SLSD

Mechanism for a Compact
JSC -
Aerobic Resistive Exercise 12/18/2009 2/28/2010 564 95 5/14/2010 $20,000
SLSD
Device
Data-Driven Forecasting of JSC -
12/22/2009 3/22/2010 579 11 5/13/2010 $30,000
Solar Events SLSD
Coordination of Sensor
Swarms for Extraterrestrial LRC 2/27/2010 4/26/2010 423 37 6/4/2010 $18,000 (3)
Research
Medical Consumables
GRC 5/17/2010 7/27/2010 365 56 10/28/2010 $15,000 (3)
Tracking
Augmenting the Exercise JSC -
5/27/2010 7/27/2010 229 18 9/20/2010 $10,000
Experience SLSD
Simple Microgravity Laundry JSC -
5/27/2010 7/27/2010
Space Life Sciences 598 108 9/21/2010 $7,500
System EA 14

yet2.com

Space Life Sciences
15

yet2.com PilotResults
Technical Need No. of total No. of hits Active leads
replies/leads (initial interest)

Bone Density Measurement 51 793 5

Monitoring of Water and 61 2003 8
Biocides

Radioprotectants 28 475 6

Exoterrestrial Life 31 1596 1
Differentiation

Food Packaging/Protection 29 173 5

Portable Imaging 34 581 5

Space Life Sciences
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Yet2.com example: Bone Imaging

Germany 6
Austria 1
Japan 7
Canada 1
France 6
Israel 1
Australia 3
Belgium 1
UK 5
Switzerland 4
Sweden 1
USA 15
Total 51

Space Life Sciences
Page 17 17

NASA@work

Space Life Sciences
18

TopCoder Experience
• Opportunity presented to NASA by Harvard Business School

• Research project to compare outcomes of collaborative and competitive teams

• NASA provided the problem statement
• Optimize algorithm that supports medical kit design

• Competition began on 11/04/2009 and lasted approximately 10 days

• 2800 solutions were submitted by 480 individuals

• Useful algorithm developed and incorporated into NASA model

• Team felt this process was more efficient than internal development

• Next steps – NASA Tournament Lab with HBS and TopCoder developed to seek many
novel optimization algorithms for ISS

Space Life Sciences
19

What is NASA Tournament Lab?
Operational Virtual Facility developed between NASA, Harvard, and TopCoder

Two Objectives –

1 What is……..
Create novel, high quality working software for algorithmic /
computational Challenges

2 Contribute towards the development of empirically validated science
of innovation tournaments

Utilize the principles of distributed innovation to allow participants worldwide to

What is……..
contribute to solving mission challenges by developing innovative computational
algorithms.
Space Life Sciences
20 Exploring Space |Enhancing Life

NASA Human Health and
Performance Center
• Membership
– 110 members: http://nhhpc.nasa.gov
– Seven NASA Centers
– International Space Station partners: JAXA, DLR
– Government orgs: FAA, GSA, USAF Research Labs, two NIH
Centers, FDA, USAID, ONR
– Academia: FAA COE (Stanford), MIT, UTMB, Tufts, Clemson
– Corporate: Philips, Johnson & Johnson, Procter &
Gamble, General
Mills, Nike, GE, PepsiCo, InnoCentive, Yet2.com, Cazneau, Pitn
ey Bowes, UnitedHealth Group, Kimberly-Clark
– Nonprofits: Mozilla, Southwest Research Institute, The
National Center for Human Performance, San Diego
Zoo, Draper Lab, Prize4Life
• Second Workshop: Connecting Through Collaboration –
Space Life Sciences
October 18, 2011 Exploring Space |Enhancing Life 21

COECI
• Form Center of Excellence for Collaborative
Innovation November 1, 2011
– Organized to develop prizes for innovation and
other collaborative techniques
– Located in the Human Exploration and Operations
Mission Directorate (HEOMD) – J Crusan, J Davis
• Staffed by JSC Space Life Sciences personnel – NASA and
Wyle
– For all federal agencies; opportunity to expand into
public-private partnerships
Space Life Sciences
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