K. David McCowen, MD, FACP, Medical Director, Diabetes
Endocrine Consultants Northwest for Franciscan Medical Group. Talking about diabetes prevention best practices.
Prevention of Type 2 Diabetes and Stemming the Tide
1. K. David McCowen, MD, FACP
Medical Director, Diabetes
Endocrine Consultants Northwest
Franciscan Medical Group
Prevention of T2DM
Stemming the Tide
2. • T2DM: 93% of all DM
• Rapid expansion of disease incidence
• Always preceded by Impaired Glucose
Tolerance (IGT) 790.21
• FBS = 100 – 125 mg/dl
• HgbA1c – 5.7 or 6.0 to 6.5 %
2 | Creating Healthier Communities | Best practices for managing high-risk clinical populations
3. Diabetes Prevention Program (DPP)
• Treated IGT patients: Life Style Changes vs Metformin (Met)
vs no intervention. Now we have 10 year data.
• Delay development of DM: LSC = 11%; Met = 3%.
• Reduction of DM incidence: LSC = 20%; Met = 8%.
• Above compared to the no intervention arm.
• Reduced microvascular, neuropathic, and CV complications.
• Quality Adjusted Life Years (QALY): cost $8800 LSC;
$29,900 Met.
• Survival up 0.5 years LSC; 0.2 years Met.
3 | Creating Healthier Communities | Best practices for managing high-risk clinical populations
4. DPP continued
• THE COST EFECTIVNESS IMPROVED WHEN THE
INTERVENTIONS WERE IMPLEMENTED IN
ROUTINE CLINICAL PRACTICE
• Last month FMG implemented a robust DM treatment
pathway.
• We included the therapy of IGT as equally (and
probably more) important than the DM1 and DM2
pathways.
4 | Creating Healthier Communities | Best practices for managing high-risk clinical populations
5. 5 | Creating Healthier Communities | Best practices for managing high-risk clinical populations
6. 6 | Creating Healthier Communities | Best practices for managing high-risk clinical populations
Identify