2. Human - Microbe Interactions
Microbes are dependent on environmental
conditions for survival.
Microbes make use of the human body as its
ecological environment.
Microbes accumulate over time immediately
after birth by simple environmental interactions.
3. Beneficial Bacteria
Bifidobacteria are vital for:
- The acidogenic bacteria in
the intestinal tract of breast-fed
infants.
- Modulation of immune
responses.
4. Beneficial Bacteria
Bifidobacteria are vital for:
-Inhibiting pathogens from
colonizing gut mucosa.
- Breaking down of foods and the intake of
nutrients into the body.
6. Probiotics
Development Reduction in Synthesis of
of mucousal pH of bowel vitamins
barrier
Immune Production of Metabolism
system short- chain of bile acids
activation fatty acids
7. Pathogenic Bacteria
Enterococcus faecalis
- Found in the intestinal tract.
- Most commonly causes urinary
tract infections.
- Epidermal parasitic skin
diseases.
- Antibiotic resistant.
9. Viral Interaction With Humans
Viruses
-Obligate cellular parasites
- Survival is entirely dependant on the
cellular system they parasitize
-Associated with being mostly pathogenic
-Also have potential beneficial relationships
with humans
10. Viruses To CURE CANCER!
Oncolytic Virotherapy
-1912, Regression of cervical cancer after
being treated with Rabies vaccine
- Genetically modified Adenovirus injected
in tumors to cause oncolysis
-Combination techniques are used to
overcome challeges
14. Viruses To CAUSE CANCER!
Oncolytic Viruses
-HTLV-1
- Causes Leukemia
-Infects T-Lymphocytes leading to
uncontrolled proliferation
15. Virus to cure Virus
HHP-6 Versus HIV-1
-Replication of HIV can be suppressed by a
co-infection of HHP-6
-Protects Dendric Cells from HIV infection
-Ultimately slows down the AIDS
16. Virus to cure Virus
HHP-6 Versus HIV-
1
-HIV (green)
budding from a T-
lymphocyte
18. References
Dishon hiebner
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asymptomatic and AIDS patients. Intervirology 41:1–9.
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727.
Ayesha Gardee
-Curiel, DT (2000). The development of conditionally replicative adenoviruses for cancer therapy. Clin Cancer Res 6:
3395–3399.
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Yusuf Dhaler
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19. References
Michael Freeman
-Fuller, R. (1989). Probiotics in man and animals. Journal of Applied Microbiology.66, 365- 378.
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Daniel Klonaros
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(2005). Diversity of the Human Intestinal Microbial Flora. Science.308, 1635-1638.
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Hamzeh Majiet
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RechercheScientifique, Universités.
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20. References
Yusuf Saboor
-Van Regenmortel MHV, Fauquet CM, Bishop DHL, Carstens EB, Estes MK, Lemon SM, Maniloff J, Mayo MA, McGeoch
DJ, Pringle CR, Wickner RB. 7th Report of the International Committee on Taxonomy of Viruses. San Diego ,
Academic Press; 2000.
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review. Am J Gastroenterol. 101:2401-2409.
Farnaaz Khan
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