Drug excretion lecture 10

DRUG EXCRETION ,[object Object],[object Object],[object Object],[object Object]

Renal excretion ,[object Object],[object Object]

Major Excretory Processes in the Nephron ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Glomerular filtration ,[object Object],[object Object],[object Object],[object Object]

Glomerular filtration (Cont) ,[object Object],[object Object],[object Object],[object Object]

Tubular secretion ,[object Object],[object Object],[object Object],[object Object]

Tubular re-absorption ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Tubular re-absorption ,[object Object],[object Object],[object Object],[object Object]

Effect of Urine pH on tubular re-absorption ,[object Object],[object Object],[object Object]

Alteration of Urine pH ,[object Object],[object Object],[object Object],[object Object]

1.0 0.0 1.0 0.0 1.32 24.0 V.Weak 4.0 F 0.83 76.0 10.26 98.0 635.2 99.9 Weak 8.0 E 0.79 99.99 12.6 100.0 794.3 100.0 Strong 12.0 D BASES 1.0 0.3 0.99 0.02 0.99 0.0 V.Weak 10.0 C 1.25 97.0 0.115 66.6 0.04 3.0 Weak 6.0 B 1.26 100.0 0.8 99.99 0.001 99.7 Strong 2.0 A Acids Urine pH Valves 7.5 Cl R Urine pH Valves 7.5 % Ionized Urine pH Valves 6.3 Cl R Urine pH Valves 6.3 % Ionized Urine pH Valves 4.5 Cl R Urine pH Valaes 4.5 % Ionized Nature pK a Drugs

Effect of Drug pka on renal clearance ,[object Object],[object Object],[object Object],[object Object]

Effect of Drug pka on renal clearance ,[object Object],[object Object],[object Object]

Effect of Drug pka on renal clearance ,[object Object],[object Object]

Effect of Drug pka on renal clearance ,[object Object]

Renal clearance ,[object Object],[object Object],[object Object],[object Object]

Renal clearance (Cont.) ,[object Object],[object Object],[object Object]

Renal clearance ,[object Object]

Hemodialysis ,[object Object],[object Object],[object Object]

Applicability of Hemodialysis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Biliary excretion ,[object Object],[object Object],[object Object]

Biliary excretion (Cont.) ,[object Object],[object Object],[object Object]

Cp versus Time showing a Second Peak

Enterohepatic Recycling (Cont.) ,[object Object],[object Object],[object Object],[object Object]

Pulmonary excretion ,[object Object],[object Object],[object Object]

Salivary excretion ,[object Object],[object Object],[object Object],[object Object]

Renal disease considerations ,[object Object],[object Object],[object Object]

Dose adjustment ,[object Object],[object Object],[object Object],[object Object],[object Object]

Creatinine clearance (Cont.) ,[object Object],[object Object],[object Object],[object Object]

Determination of creatinine clearance ,[object Object]

Determination of creatinine clearance (Cont.) ,[object Object],[object Object],[object Object],[object Object],[object Object]

Calculation of creatinine clearance ,[object Object],[object Object],[object Object]

Drug excretion lecture 10

Recomendados

Recomendados

Más contenido relacionado

La actualidad más candente

La actualidad más candente (20)

Destacado

Destacado (14)

Similar a Drug excretion lecture 10

Similar a Drug excretion lecture 10 (20)

Más de homebwoi

Más de homebwoi (16)

Último

Último (20)

Drug excretion lecture 10