8. Epiblast cells that do migrate down (ventrally) through the primitive streak during later stages of gastrulation constitute the mesoderm layer ( dull red in 16 day image at lower right ) day 16 14-15 days 16 days 2 wks
9. Human embryo during gastrulation Carlson Fig. 5-4 (p86)+ 5-5 (p87) transverse section
10. Derivatives of the bilaminar embryo Carlson Fig. 5-1 (p84) Laminae of bilaminar embryo Extraembryonic mesoderm
11. Though early on you were a quite flat disk, now are a doughnut http://www.abdn.ac.uk/langling/resources/usflimgs.html [And what is in the middle?]
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14. Major subdivisions of the mesoderm Sadler 3-4 (p19) “ parietal” (wall) layer “ visceral” (organ) layer
15. Postnatal derivatives of embryonic mesoderm From Carlson 6-25 (p125) Embryonic mesoderm Intermediate mesoderm Urogenital system (kidney, ureter, not bladder adrenal cortex gonads not gametes) Vagina, uterus, uterine tubes Dermis of skin Skeleton (axial, not limb ) Lateral mesoderm Paraxial mesoderm Muscles (axial & limb) Splanchnic mesoderm Somatic mesoderm Skeleton ( not axial , limb) Parietal pleura pericardium peritoneum Visceral pleura peritoneum Mesenteries Blood cells, blood vessel endothelium, endocardium Respiratory tract wall Gut wall Epicardium Myocardium somatic = “parietal” = wall layer. For gut and gut derivatives, the parietal layer lines body wall. splanchnic = visceral = organ layer epicardium= visceral pericardium
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19. Mesodermal origin of muscle From Carlson 6-25 (p125) Embryonic mesoderm Intermediate mesoderm Urogenital system (kidney, ureter, not bladder adrenal cortex gonads not gametes) Vagina, uterus, uterine tubes Dermis of skin Skeleton (axial, not limb) Lateral mesoderm Paraxial mesoderm Muscles (axial & limb) Splanchnic mesoderm Somatic mesoderm Skeleton (not axial, limb) Parietal pleura pericardium peritoneum Visceral pleura peritoneum Mesenteries Blood cells, blood vessel endothelium, endocardium Respiratory tract wall Gut wall Epicardium Myocardium skeletal cardiac smooth
30. Postnatal derivatives of embryonic mesoderm From Carlson 6-25 (p125) Embryonic mesoderm Intermediate mesoderm Urogenital system (kidney, ureter, not bladder adrenal cortex gonads not gametes) Vagina, uterus, uterine tubes Dermis of skin Skeleton (axial, not limb ) Lateral mesoderm Paraxial mesoderm Muscles (axial & limb) Splanchnic mesoderm Somatic mesoderm Skeleton ( not axial , limb) Parietal pleura pericardium peritoneum Visceral pleura peritoneum Mesenteries Blood cells, blood vessel endothelium, endocardium Respiratory tract wall Gut wall Epicardium Myocardium somatic = “parietal” = wall layer. For gut and gut derivatives, the parietal layer lines body wall. splanchnic = visceral = organ layer epicardium= visceral pericardium
31. Postnatal derivatives of embryonic mesoderm From Carlson 6-25 (p125) Embryonic mesoderm Intermediate mesoderm Lateral mesoderm Paraxial mesoderm Splanchnic mesoderm Somatic mesoderm Parietal parietal pleura parietal pericardium parietal peritoneum Visceral visceral pleura visceral pericardium visceral peritoneum Mesenteries somatic = “parietal” = wall layer. For example, gut and gut derivatives, the parietal layer lines body wall. splanchnic = visceral = organ layer epicardium= visceral pericardium
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Notas del editor
Sources used in preparing these lectures include: Carlson (2004) Human embryology and developmental biology, 3rd Edition. St. Louis, Mo.: Mosby. Dye (2002) Dictionary of developmental biology and embryology. New York: Wiley-Liss. Moore (2003) The developing human : clinically oriented embryology, 7th . Edition. Philadelphia, Pa.: Saunders. [Emory lib has 7 th on reserve; actually, I used the 6 th edition, 1998. This was the source I used the least. ] Sadler (2005) Langman's essential medical embryology. Philadelphia: Lippincott Williams & Wilkins. [Unfortunately Emory lib appears not to have this. I may ask them to get it -- clear, concise exposition. Also includes a glossary & many scanning EMs. Alas, no problems. ] Wolpert (2002) Principles of development, 2nd Edition. Oxford: Oxford University Press. [Experimental/molecular embryology: not clinically oriented.] Image from Sadler Fig. 3-4 (p19)
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