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Modelling the Diluting Effect of Social Mobility
                 on Health Inequality

                             Heather Turner1,2 and David Firth1

                                       1
                                      University of Warwick, UK
                             2   Independent statistical/R consultant


                                           5 September 2012



H. Turner and D. Firth (Warwick, UK)       Social Mobility & Health Inequality   RSS 2012   1 / 19
Setting


 Given intergenerational data on

         socio-economic position (origin, destination)
         health outcome
         covariates

 how can we analyse the effect of social mobility on health?




H. Turner and D. Firth (Warwick, UK)   Social Mobility & Health Inequality   RSS 2012   2 / 19
Trajectory Analysis

 A common approach is to analyse the effect of social mobility by
 considering all possible moves from origin class to destination class.

 These trajectories are then used to produce

         descriptive statistics
         statistical models

 Often the social classes are merged into two categories, so that the
 trajectories are simplified to up/stable high/stable low/down.



H. Turner and D. Firth (Warwick, UK)     Social Mobility & Health Inequality   RSS 2012   3 / 19
Bartley & Plewis Models

 Bartley & Plewis (JRSSA, 2007) used a more sophisticated approach,
 in which social mobility effects were combined first with the effect of
 origin class and second with the effect of destination class.

 For example the origin + mobility model includes the term
                             
                             αi + δ0 i > j
                             
                        θij = αi + δ1 i = j
                             
                               αi + δ2 i < j
                             

 where αi is the effect for origin i and i > j denotes moving to a more
 favourable destination class.

H. Turner and D. Firth (Warwick, UK)   Social Mobility & Health Inequality   RSS 2012   4 / 19
Case Study: Long-term Limiting Illness


 This application presented by Bartley & Plewis concerns data from
 the ONS Longitudinal Survey, which links census and vital event data
 for 1% of the population of England and Wales.

 The outcome of interest is long-term limiting illness (LLTI)

         a long-standing illness, health problem or handicap that
         limits a person’s activities or the work they can do




H. Turner and D. Firth (Warwick, UK)   Social Mobility & Health Inequality   RSS 2012   5 / 19
Model Scope


 The probability of long-term limiting illness in 2001 was modelled via
 logistic regression.

 The social mobility effects θij were based on the National Statistics
 socio-economic classification (7 classes, high man/prof to routine) in
 1991 and 2001.

 Age in 1991 was included as a covariate and men and women were
 modelled separately.




H. Turner and D. Firth (Warwick, UK)   Social Mobility & Health Inequality   RSS 2012   6 / 19
Social Mobility Effects
 The exponential of the mobility parameters gives the odds ratios of
 LLTI, shown here for men


                                       Origin + Mobility Destination + Mobility
     To more favourable                          1.00                        1.00
     Stable                                      1.21                        0.71
     To less favourable                          1.45                        0.52


         given origin, odds of LLTI increased by downward mobility
         given destination, odds of LLTI decreased by downward mobility

H. Turner and D. Firth (Warwick, UK)   Social Mobility & Health Inequality          RSS 2012   7 / 19
Weighted Residuals

 The working residuals from the IWLS iterations can be averaged over
 each origin-destination combination to provide an indicator of fit for
 each trajectory
                                rijs wijs
                                 i,j,s wijs

 where rijs is the s th residual for origin i and destination j, and wijs
 is the corresponding working weight.

 These average residuals can be standardized to be approximately
 N(0, 1) assuming the model is correct.



H. Turner and D. Firth (Warwick, UK)     Social Mobility & Health Inequality   RSS 2012   8 / 19
> mosaic(model1men, ~mnssec9 + mnssec0, set_varnames = list(mnssec9 = "Origin class",
                                                            > mosaic(model2men, ~mnssec9 + mnssec0, set_varnames =
  +     mnssec0 = "Destination class"), set_labels = list(mnssec9 = 1:7,
                                                            +     mnssec0 = "Destination class"), set_labels = lis
  +     mnssec0 = 1:7), rot_labels = c(0, 0), margins = c(1, 1, 0,
                                                            +     mnssec0 = 1:7), rot_labels = c(0, 0), margins =
  +     4))
                                                            +     4))
                                Origin + Mobility                                                              Destination + Mobility
                                       Destination class                                                               Destination class
                                   1                       2   3 4 5 67                                            1                       2    3 4 5 67
                                                                          Mean                                                                             Mean
                     1                                                    residual                                                                         residual
                                                                                                           1
                                                                                3.99
                                                                                                                                                                 4.00
                     2                                                                                     2
                                                                               2.00
                                                                                                                                                                 2.00
                     3
      Origin class




                                                                                                           3




                                                                                            Origin class
                     4                                                         0.00
                                                                                                           4
                                                                                                                                                                 0.00
                     5                                                                                     5
                                                                              −2.00

                     6                                                                                                                                          −2.00
                                                                                                           6

                                                                              −4.17                                                                             −3.45
                     7                                                                                     7
                                                                          p−value =                                                                        p−value =
                                                                          6.1194e−16                                                                       < 2.22e−16




 Despite being two sides of the same coin, the two models capture
 > mosaic(model2men, ~mnssec9 + mnssec0, set_varnames = list(mnssec9 = "Origin class",
 different features of the data. = list(mnssec9 = 1:7,
 +     mnssec0 = "Destination class"), set_labels
                                                                                       17
  +                      mnssec0 = 1:7), rot_labels = c(0, 0), margins = c(1, 1, 0,
  +                      4))



                                       Destination class
                                   1                       2   3 4 5 67
H. Turner and D. Firth (Warwick, UK)                               Social Mean
                                                                          Mobility & Health Inequality                                         RSS 2012       9 / 19
Diagonal Reference Model


 Sobel (Amer. Soc. Rev, 1991) proposed the diagonal reference
 model, which combines origin, destination and social mobility effects

                                       w1 γi + (1 − w1 )γj

 The effect of moving from class i to class j is a weighted sum of the
 diagonal effects γi , where γi is the effect for stable individuals in that
 class.




H. Turner and D. Firth (Warwick, UK)   Social Mobility & Health Inequality   RSS 2012   10 / 19
Model Estimation

 The diagonal reference model has predominantly been used to model
 political and social attitudes, where a nonlinear least squares model is
 appropriate.

 Here we have a binary outcome and wish to model the log odds,
 producing a logistic model with nonlinear terms.

 Most statistical software packages do not have the facilities to
 estimate such a model “out-of-the-box”. However this is a particular
 example of a generalized nonlinear model which may be fitted using
 the gnm package for R (Turner and Firth, R News, 2007).



H. Turner and D. Firth (Warwick, UK)    Social Mobility & Health Inequality   RSS 2012   11 / 19
Generalized Nonlinear Models
 Given a response variable Y , a generalized nonlinear model maps the
 mean response E(Y ) = µ to a parameteric model or predictor via a
 link function g:
                            g(µ) = η(x, β)
 The model is completed by a variance function V (µ) describing how
 Var(Y ) depends on µ.

 For our logistic model g is the logit function and V (µ) is determined
 by assuming a binomial distribution for the response.

 Following the previous analysis we fit the diagonal reference model
 with age as a covariate and fit models for men and women separately.


H. Turner and D. Firth (Warwick, UK)   Social Mobility & Health Inequality   RSS 2012   12 / 19
Diagonal Effects

 The model for the stable individuals is an ordinary logistic regression

                                  logit(piik ) = β0 + β1 agek + γi

 Therefore the diagonal effects are log odds ratios of LLTI in class i
 against the reference class for a given age

                                  piik /(1 − piik )
                               log
                                 p11k /(1 − p11k )
                           =(β0 + β1 agek + γi ) − (β0 + β1 agek )
                           =γi



H. Turner and D. Firth (Warwick, UK)    Social Mobility & Health Inequality   RSS 2012   13 / 19
Health Inequality
                   q    men
                   q    women
                                                                                                    q
               4




                                                                                                        q
                                                                                          q
  Odds Ratio

               3




                                                q                               q
                                                                            q
                                                                                              q

                                                               q
               2




                                     q   q           q             q




                         q   q
               1




                       high prof   low prof   intermed      self empl     low sup   semi−routine   routine

                                                    Socio−economic Position




H. Turner and D. Firth (Warwick, UK)                Social Mobility & Health Inequality                      RSS 2012   14 / 19
Diluting Effect of Social Mobility

 The ratio of origin weight to destination weight quantifies the
 diluting effect of social mobility on health inequality

           1:0 social mobility has no effect on individual
           0:1 social mobility has no effect on inequality
     otherwise social mobility increases P(LLTI) in the upper classes
               and decreases P(LLTI) in the lower classes.

 The larger the origin weight, the greater the diluting effect.



H. Turner and D. Firth (Warwick, UK)   Social Mobility & Health Inequality   RSS 2012   15 / 19
Diagonal Weights

 The diagonal weights for the LLTI models are


                                                     Men                      Women
                           Origin      0.62 (0.03) 0.41 (0.03)
                           Destination 0.38 (0.03) 0.59 (0.03)


 Since their destination class is given more weight, social mobility has
 a greater impact for women.



H. Turner and D. Firth (Warwick, UK)    Social Mobility & Health Inequality           RSS 2012   16 / 19
Model Comparison
 The models can be compared by the difference in deviance from the
 null model:

                                                         Men       Women
                                                     Deviance Df Deviance Df
             Origin + mobility                           4050              9   3194      9
             Destination + mobility                      4026              9   3273      9
             Diagonal reference                          4121              8   3312      8


 The diagonal reference model reduces the deviance the most despite
 requiring fewer degrees of freedom.

H. Turner and D. Firth (Warwick, UK)     Social Mobility & Health Inequality          RSS 2012   17 / 19
> mosaic(drefmen, ~mnssec9 + mnssec0, set_varnames = list(mnssec9 = "Origin class",+ mnssec0, set_varnames = list
                                                       > mosaic(drefwomen, ~mnssec9
 +     mnssec0 = "Destination class"), set_labels = list(mnssec9 = 1:7,"Destination class"), set_labels = list(mns
                                                       +     mnssec0 =
 +     mnssec0 = 1:7), rot_labels = c(0, 0), margins = +
                                                       c(1, 1, 0,
                                                             mnssec0 = 1:7), rot_labels = c(0, 0), margins = c(1,
 +     4))                                             +     4))

                                   Men                                                                 Women
                           Destination class                                                       Destination class
                       1                       2   3 4 5 67                                    1                  2    3   45 67
                                                              Mean                                                                 Mean
                   1                                          residual                     1
                                                                                                                                   residual
                                                                    3.38                                                                 2.71
                                                                                           2
                   2                                                                                                                     2.00
                                                                   2.00

                   3
    Origin class




                                                                                           3




                                                                            Origin class
                   4                                               0.00                                                                  0.00
                                                                                           4
                   5                                                                       5

                                                                  −2.00                    6
                   6                                                                                                                   −2.00

                                                                  −3.28                                                                −2.91
                   7
                                                              p−value =                    7                                       p−value =
                                                              4.6821e−05                                                           0.00028829




 The presence of large residuals on the diagonal in the model for
 women suggests that the covariate adjustment is inadequate.
 > mosaic(model1men, ~mnssec9 + mnssec0, type = "expected", set_varnames = list(mnssec9 mnssec0, type = "expected"
 +
                                                       > mosaic(model1women, ~mnssec9 + = "Origin class",
       mnssec0 = "Destination class"), set_labels = list(mnssec9 = 1:7,"Destination class"), set_labels = list(mns
                                                       +     mnssec0 =
 +     mnssec0 = 1:7), rot_labels = c(0, 0), margins = +
                                                       c(1, 1, 0,
                                                             mnssec0 = 1:7), rot_labels = c(0, 0), margins = c(1,
 +     4))                                             +     4))



                           Destination class                                                       Destination class
                       1                   2       3 4 5 67                                    1                 2     3   45 67
H. Turner and D. Firth (Warwick, UK)
      1                                                 SocialMean
                                                               Mobility & Health Inequality
                                                                              1                                            RSS 2012
                                                                                                                                  Mean     18 / 19
Summary

 Diagonal reference models provide a parsimonious and interpretable
 model for inequality between classes and the effects of social mobility
 on this inequality.

 gnm (www.cran.r-project.org/package=gnm) enables these
 models to be easily applied to binary as well as continuous responses.

 Further examples are provided in the package vignette including
 allowing the diagonal weight to depend on covariates, e.g. to fit
 separate weights for upwardly/downwardly mobile.



H. Turner and D. Firth (Warwick, UK)   Social Mobility & Health Inequality   RSS 2012   19 / 19

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Modelling the Diluting Effect of Social Mobility on Health Inequality

  • 1. Modelling the Diluting Effect of Social Mobility on Health Inequality Heather Turner1,2 and David Firth1 1 University of Warwick, UK 2 Independent statistical/R consultant 5 September 2012 H. Turner and D. Firth (Warwick, UK) Social Mobility & Health Inequality RSS 2012 1 / 19
  • 2. Setting Given intergenerational data on socio-economic position (origin, destination) health outcome covariates how can we analyse the effect of social mobility on health? H. Turner and D. Firth (Warwick, UK) Social Mobility & Health Inequality RSS 2012 2 / 19
  • 3. Trajectory Analysis A common approach is to analyse the effect of social mobility by considering all possible moves from origin class to destination class. These trajectories are then used to produce descriptive statistics statistical models Often the social classes are merged into two categories, so that the trajectories are simplified to up/stable high/stable low/down. H. Turner and D. Firth (Warwick, UK) Social Mobility & Health Inequality RSS 2012 3 / 19
  • 4. Bartley & Plewis Models Bartley & Plewis (JRSSA, 2007) used a more sophisticated approach, in which social mobility effects were combined first with the effect of origin class and second with the effect of destination class. For example the origin + mobility model includes the term  αi + δ0 i > j  θij = αi + δ1 i = j  αi + δ2 i < j  where αi is the effect for origin i and i > j denotes moving to a more favourable destination class. H. Turner and D. Firth (Warwick, UK) Social Mobility & Health Inequality RSS 2012 4 / 19
  • 5. Case Study: Long-term Limiting Illness This application presented by Bartley & Plewis concerns data from the ONS Longitudinal Survey, which links census and vital event data for 1% of the population of England and Wales. The outcome of interest is long-term limiting illness (LLTI) a long-standing illness, health problem or handicap that limits a person’s activities or the work they can do H. Turner and D. Firth (Warwick, UK) Social Mobility & Health Inequality RSS 2012 5 / 19
  • 6. Model Scope The probability of long-term limiting illness in 2001 was modelled via logistic regression. The social mobility effects θij were based on the National Statistics socio-economic classification (7 classes, high man/prof to routine) in 1991 and 2001. Age in 1991 was included as a covariate and men and women were modelled separately. H. Turner and D. Firth (Warwick, UK) Social Mobility & Health Inequality RSS 2012 6 / 19
  • 7. Social Mobility Effects The exponential of the mobility parameters gives the odds ratios of LLTI, shown here for men Origin + Mobility Destination + Mobility To more favourable 1.00 1.00 Stable 1.21 0.71 To less favourable 1.45 0.52 given origin, odds of LLTI increased by downward mobility given destination, odds of LLTI decreased by downward mobility H. Turner and D. Firth (Warwick, UK) Social Mobility & Health Inequality RSS 2012 7 / 19
  • 8. Weighted Residuals The working residuals from the IWLS iterations can be averaged over each origin-destination combination to provide an indicator of fit for each trajectory rijs wijs i,j,s wijs where rijs is the s th residual for origin i and destination j, and wijs is the corresponding working weight. These average residuals can be standardized to be approximately N(0, 1) assuming the model is correct. H. Turner and D. Firth (Warwick, UK) Social Mobility & Health Inequality RSS 2012 8 / 19
  • 9. > mosaic(model1men, ~mnssec9 + mnssec0, set_varnames = list(mnssec9 = "Origin class", > mosaic(model2men, ~mnssec9 + mnssec0, set_varnames = + mnssec0 = "Destination class"), set_labels = list(mnssec9 = 1:7, + mnssec0 = "Destination class"), set_labels = lis + mnssec0 = 1:7), rot_labels = c(0, 0), margins = c(1, 1, 0, + mnssec0 = 1:7), rot_labels = c(0, 0), margins = + 4)) + 4)) Origin + Mobility Destination + Mobility Destination class Destination class 1 2 3 4 5 67 1 2 3 4 5 67 Mean Mean 1 residual residual 1 3.99 4.00 2 2 2.00 2.00 3 Origin class 3 Origin class 4 0.00 4 0.00 5 5 −2.00 6 −2.00 6 −4.17 −3.45 7 7 p−value = p−value = 6.1194e−16 < 2.22e−16 Despite being two sides of the same coin, the two models capture > mosaic(model2men, ~mnssec9 + mnssec0, set_varnames = list(mnssec9 = "Origin class", different features of the data. = list(mnssec9 = 1:7, + mnssec0 = "Destination class"), set_labels 17 + mnssec0 = 1:7), rot_labels = c(0, 0), margins = c(1, 1, 0, + 4)) Destination class 1 2 3 4 5 67 H. Turner and D. Firth (Warwick, UK) Social Mean Mobility & Health Inequality RSS 2012 9 / 19
  • 10. Diagonal Reference Model Sobel (Amer. Soc. Rev, 1991) proposed the diagonal reference model, which combines origin, destination and social mobility effects w1 γi + (1 − w1 )γj The effect of moving from class i to class j is a weighted sum of the diagonal effects γi , where γi is the effect for stable individuals in that class. H. Turner and D. Firth (Warwick, UK) Social Mobility & Health Inequality RSS 2012 10 / 19
  • 11. Model Estimation The diagonal reference model has predominantly been used to model political and social attitudes, where a nonlinear least squares model is appropriate. Here we have a binary outcome and wish to model the log odds, producing a logistic model with nonlinear terms. Most statistical software packages do not have the facilities to estimate such a model “out-of-the-box”. However this is a particular example of a generalized nonlinear model which may be fitted using the gnm package for R (Turner and Firth, R News, 2007). H. Turner and D. Firth (Warwick, UK) Social Mobility & Health Inequality RSS 2012 11 / 19
  • 12. Generalized Nonlinear Models Given a response variable Y , a generalized nonlinear model maps the mean response E(Y ) = µ to a parameteric model or predictor via a link function g: g(µ) = η(x, β) The model is completed by a variance function V (µ) describing how Var(Y ) depends on µ. For our logistic model g is the logit function and V (µ) is determined by assuming a binomial distribution for the response. Following the previous analysis we fit the diagonal reference model with age as a covariate and fit models for men and women separately. H. Turner and D. Firth (Warwick, UK) Social Mobility & Health Inequality RSS 2012 12 / 19
  • 13. Diagonal Effects The model for the stable individuals is an ordinary logistic regression logit(piik ) = β0 + β1 agek + γi Therefore the diagonal effects are log odds ratios of LLTI in class i against the reference class for a given age piik /(1 − piik ) log p11k /(1 − p11k ) =(β0 + β1 agek + γi ) − (β0 + β1 agek ) =γi H. Turner and D. Firth (Warwick, UK) Social Mobility & Health Inequality RSS 2012 13 / 19
  • 14. Health Inequality q men q women q 4 q q Odds Ratio 3 q q q q q 2 q q q q q q 1 high prof low prof intermed self empl low sup semi−routine routine Socio−economic Position H. Turner and D. Firth (Warwick, UK) Social Mobility & Health Inequality RSS 2012 14 / 19
  • 15. Diluting Effect of Social Mobility The ratio of origin weight to destination weight quantifies the diluting effect of social mobility on health inequality 1:0 social mobility has no effect on individual 0:1 social mobility has no effect on inequality otherwise social mobility increases P(LLTI) in the upper classes and decreases P(LLTI) in the lower classes. The larger the origin weight, the greater the diluting effect. H. Turner and D. Firth (Warwick, UK) Social Mobility & Health Inequality RSS 2012 15 / 19
  • 16. Diagonal Weights The diagonal weights for the LLTI models are Men Women Origin 0.62 (0.03) 0.41 (0.03) Destination 0.38 (0.03) 0.59 (0.03) Since their destination class is given more weight, social mobility has a greater impact for women. H. Turner and D. Firth (Warwick, UK) Social Mobility & Health Inequality RSS 2012 16 / 19
  • 17. Model Comparison The models can be compared by the difference in deviance from the null model: Men Women Deviance Df Deviance Df Origin + mobility 4050 9 3194 9 Destination + mobility 4026 9 3273 9 Diagonal reference 4121 8 3312 8 The diagonal reference model reduces the deviance the most despite requiring fewer degrees of freedom. H. Turner and D. Firth (Warwick, UK) Social Mobility & Health Inequality RSS 2012 17 / 19
  • 18. > mosaic(drefmen, ~mnssec9 + mnssec0, set_varnames = list(mnssec9 = "Origin class",+ mnssec0, set_varnames = list > mosaic(drefwomen, ~mnssec9 + mnssec0 = "Destination class"), set_labels = list(mnssec9 = 1:7,"Destination class"), set_labels = list(mns + mnssec0 = + mnssec0 = 1:7), rot_labels = c(0, 0), margins = + c(1, 1, 0, mnssec0 = 1:7), rot_labels = c(0, 0), margins = c(1, + 4)) + 4)) Men Women Destination class Destination class 1 2 3 4 5 67 1 2 3 45 67 Mean Mean 1 residual 1 residual 3.38 2.71 2 2 2.00 2.00 3 Origin class 3 Origin class 4 0.00 0.00 4 5 5 −2.00 6 6 −2.00 −3.28 −2.91 7 p−value = 7 p−value = 4.6821e−05 0.00028829 The presence of large residuals on the diagonal in the model for women suggests that the covariate adjustment is inadequate. > mosaic(model1men, ~mnssec9 + mnssec0, type = "expected", set_varnames = list(mnssec9 mnssec0, type = "expected" + > mosaic(model1women, ~mnssec9 + = "Origin class", mnssec0 = "Destination class"), set_labels = list(mnssec9 = 1:7,"Destination class"), set_labels = list(mns + mnssec0 = + mnssec0 = 1:7), rot_labels = c(0, 0), margins = + c(1, 1, 0, mnssec0 = 1:7), rot_labels = c(0, 0), margins = c(1, + 4)) + 4)) Destination class Destination class 1 2 3 4 5 67 1 2 3 45 67 H. Turner and D. Firth (Warwick, UK) 1 SocialMean Mobility & Health Inequality 1 RSS 2012 Mean 18 / 19
  • 19. Summary Diagonal reference models provide a parsimonious and interpretable model for inequality between classes and the effects of social mobility on this inequality. gnm (www.cran.r-project.org/package=gnm) enables these models to be easily applied to binary as well as continuous responses. Further examples are provided in the package vignette including allowing the diagonal weight to depend on covariates, e.g. to fit separate weights for upwardly/downwardly mobile. H. Turner and D. Firth (Warwick, UK) Social Mobility & Health Inequality RSS 2012 19 / 19