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AUTOMATIC 3-D SEGMENTATION OF ENDOCARDIAL BORDER OF THE LEFT
VENTRICLE FROM ULTRASOUND IMAGES
By
A
PROJECT REPORT
Submitted to the Department of electronics &communication Engineering in the
FACULTY OF ENGINEERING & TECHNOLOGY
In partial fulfillment of the requirements for the award of the degree
Of
MASTER OF TECHNOLOGY
IN
ELECTRONICS &COMMUNICATION ENGINEERING
APRIL 2016
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CERTIFICATE
Certified that this project report titled “Automatic 3-D Segmentation of Endocardial Border of
the Left Ventricle From Ultrasound Images” is the bonafide work of Mr. _____________Who
carried out the research under my supervision Certified further, that to the best of my knowledge
the work reported herein does not form part of any other project report or dissertation on the basis
of which a degree or award was conferred on an earlier occasion on this or any other candidate.
Signature of the Guide Signature of the H.O.D
Name Name
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DECLARATION
I hereby declare that the project work entitled “Automatic 3-D Segmentation of Endocardial
Border of the Left Ventricle From Ultrasound Images” Submitted to BHARATHIDASAN
UNIVERSITY in partial fulfillment of the requirement for the award of the Degree of MASTER
OF APPLIED ELECTRONICS is a record of original work done by me the guidance of
Prof.A.Vinayagam M.Sc., M.Phil., M.E., to the best of my knowledge, the work reported here
is not a part of any other thesis or work on the basis of which a degree or award was conferred on
an earlier occasion to me or any other candidate.
(Student Name)
(Reg.No)
Place:
Date:
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ACKNOWLEDGEMENT
I am extremely glad to present my project “Automatic 3-D Segmentation of Endocardial Border
of the Left Ventricle From Ultrasound Images” which is a part of my curriculum of third
semester Master of Science in Computer science. I take this opportunity to express my sincere
gratitude to those who helped me in bringing out this project work.
I would like to express my Director,Dr. K. ANANDAN, M.A.(Eco.), M.Ed., M.Phil.,(Edn.),
PGDCA., CGT., M.A.(Psy.)of who had given me an opportunity to undertake this project.
I am highly indebted to Co-OrdinatorProf. Muniappan Department of Physics and thank from
my deep heart for her valuable comments I received through my project.
I wish to express my deep sense of gratitude to my guide
Prof. A.Vinayagam M.Sc., M.Phil., M.E., for her immense help and encouragement for
successful completion of this project.
I also express my sincere thanks to the all the staff members of Computer science for their kind
advice.
And last, but not the least, I express my deep gratitude to my parents and friends for their
encouragement and support throughout the project.
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ABSTRACT:
The segmentation of the left ventricle (LV) is an important task to assess the cardiac
function in ultrasound images of the heart. This paper presents a novel methodology for the
segmentation of the LV in three-dimensional (3-D) echocardiographic images based on the
probabilistic data association filter (PDAF). The proposed methodology begins by initializing a 3-
D deformable model either semiautomatically, with user input, or automatically, and it comprises
the following feature hierarchical approach: 1) edge detection in the vicinity of the surface
(lowlevel features); 2) edge grouping to obtain potential LV surface patches (mid-level features);
and 3) patch filtering using a shapePDAF framework (high-level features). This method provides
good performance accuracy in 20 echocardiographic volumes, and compares favorably with the
state-of-the-art segmentation methodologies proposed in the recent literature.
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INTRODUCTION:
The automatic segmentation of the LV endocardium from ultrasound (US) images is a
crucial step to characterize heart functionality, e.g., ejection fraction. In a clinical setup, there are
several advantages involved in solving this problem in echocardiography. This includes the
increase of patient throughput and the reduction of interuser variability in the LV delineation
procedure. Although other imaging techniques, such as MRI and CT, provide images with better
spatial resolution, echocardiography is still one of the most preferred modalities due to its temporal
resolution, versatility, and low cost. However, automatic segmentation in echocardiography is not
a simple task since it raises several challenges. First, the US images may contain more than one
anatomical structure, meaning that it is necessary to correctly identify the region of interest (i.e.,
initialization procedure). Second, the borders of those structures may not always be present and
they are often difficult to locate due to misleading edges and background noise.
This problem is particularly accentuated in echocardiographic images, characterized by
low signal-to-noise ratio, weak echoes, scattering, echo dropouts, and presence of speckle (i.e.,
cluttered background and outliers).Deformable models have been one of the most promising
approaches to the segmentation in echocardiographic images. However, they still face two major
issues. First, the initialization has a significant influence in the segmentation. This means that
different initializations may provide different final shape estimates, introducing user-dependent
bias. An automatic initialization solves this problem by guaranteeing that, for a specific volume,
the final segmentations are consistent. Second, the presence of clutter hampers the accuracy of the
segmentations. Most approaches do not have the ability to identify which image features (e.g.,
edge points) actually belong to the object of interest and which belong to the background noise or
neighboring structures.
This may cause the final segmentation to be poorer since erroneous edges have a negative
impact in the adaptation of the deformable model. These problems have been the subject of intense
research in the past decades and are the main concern of this paper. This paper proposes a new
algorithm based on deformable models, tailored to perform the segmentation of the LV in
threedimensional (3-D) echocardiographic images targeted to account for the difficulties
mentioned previously, i.e., initialization and presence of outliers and cluttered background. To
achieve this goal, we propose
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1) different initialization procedures along with
2) a probabilistic data association filter (PDAF) allowing for the robustness against the
presence of clutter.
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ECWAY TECHNOLOGIES
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CONCLUSION:
This paper presents a 3-D segmentation system that is able to segment the LV in
echocardiographic volumes. The methodology is based on the use of a probabilistic data
association filter, originally proposed in the context of control theory, to improve the detection of
the ventricle boundary. The proposed segmentation system was coupled with an automatic
initialization method to produce a fully automatic segmentation procedure that achieved
competitive results when compared to a semiautomatic initialization based on space-carving. The
results show that the proposed system performs well in a varied set of echocardiographic volumes.
It also shows that the accuracy of the segmentations is competitive with other stateof-the-art works.
OUR OFFICES @CHENNAI/ TRICHY / KARUR / ERODE / MADURAI / SALEM / COIMBATORE / BANGALORE / HYDRABAD
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ECWAY TECHNOLOGIES
IEEE SOFTWARE | EMBEDDED | MECHANICAL | ROBOTICS PROJECTS DEVELOPMENT
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REFERENCES:
[1] R. Juang, E. McVeigh, B. Hoffmann, D. Yuh, and P. Burlina, “Automatic segmentation of the
left-ventricular cavity and atrium in 3D ultrasound using graph cuts and the radial symmetry
transform,” in Proc. IEEE Int. Symp. Biomed. Imag., 2011, pp. 606–609.
[2] F. Orderud and S. Rabben, “Real-time 3D segmentation of the left ventricle using deformable
subdivision surfaces,” in Proc. Comput. Vis. Pattern Recog., 2008, pp. 1–8.
[3] H. Liu and P. Shi, “State-space analysis of cardiac motion with biomechanical constraints,”
IEEE Trans. Imag. Proc., vol. 16, no. 4, pp. 901–917, Apr. 2007.
[4] X. Hang, N. Greenberg, and J. Thomas, “Left ventricle quantification in 3D echocardiography
using a geometric deformable model,” Comput. Cardiol., pp. 649–652, 2005.
[5] Y. Honggang, M. Pattichis, and M. Goens, “Robust segmentation and volumetric registration
in a multi-view 3D freehand ultrasound reconstruction system,” in Proc. Asilomar Conf. Signals
Syst. Comput., 2006, pp. 1058–6393.
[6] V. Zagrodsky, V. Walimbe, C. Castro-Pareja, J. X. Qin, J.-M. Song, and R. Shekhar,
“Registration-assisted segmentation of real-time 3D echocardiographic data using deformable
models,” IEEE Trans. Med. Imag., vol. 24, no. 9, pp. 1089–1099, Sep. 2005.
[7] L. Yang, B. Georgescu, Y. Zheng, P. Meer, and D. Comaniciu, “3D ultrasound tracking of the
left ventricle using one-step forward prediction and data fusion of collaborative trackers,” in Proc.
Comput. Vis. Pattern Recog., 2008, pp. 1–8.

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Automatic 3 d segmentation of endocardial border of the left ventricle from ultrasound images

  • 1. OUR OFFICES @CHENNAI/ TRICHY / KARUR / ERODE / MADURAI / SALEM / COIMBATORE / BANGALORE / HYDRABAD CELL: +91 9894917187 | 875487 1111 / 2111 / 3111 / 4111 / 5111 / 6111 ECWAY TECHNOLOGIES IEEE SOFTWARE | EMBEDDED | MECHANICAL | ROBOTICS PROJECTS DEVELOPMENT Visit: www.ecwaytechnologies.com | www.ecwayprojects.com Mail to: ecwaytechnologies@gmail.com AUTOMATIC 3-D SEGMENTATION OF ENDOCARDIAL BORDER OF THE LEFT VENTRICLE FROM ULTRASOUND IMAGES By A PROJECT REPORT Submitted to the Department of electronics &communication Engineering in the FACULTY OF ENGINEERING & TECHNOLOGY In partial fulfillment of the requirements for the award of the degree Of MASTER OF TECHNOLOGY IN ELECTRONICS &COMMUNICATION ENGINEERING APRIL 2016
  • 2. OUR OFFICES @CHENNAI/ TRICHY / KARUR / ERODE / MADURAI / SALEM / COIMBATORE / BANGALORE / HYDRABAD CELL: +91 9894917187 | 875487 1111 / 2111 / 3111 / 4111 / 5111 / 6111 ECWAY TECHNOLOGIES IEEE SOFTWARE | EMBEDDED | MECHANICAL | ROBOTICS PROJECTS DEVELOPMENT Visit: www.ecwaytechnologies.com | www.ecwayprojects.com Mail to: ecwaytechnologies@gmail.com CERTIFICATE Certified that this project report titled “Automatic 3-D Segmentation of Endocardial Border of the Left Ventricle From Ultrasound Images” is the bonafide work of Mr. _____________Who carried out the research under my supervision Certified further, that to the best of my knowledge the work reported herein does not form part of any other project report or dissertation on the basis of which a degree or award was conferred on an earlier occasion on this or any other candidate. Signature of the Guide Signature of the H.O.D Name Name
  • 3. OUR OFFICES @CHENNAI/ TRICHY / KARUR / ERODE / MADURAI / SALEM / COIMBATORE / BANGALORE / HYDRABAD CELL: +91 9894917187 | 875487 1111 / 2111 / 3111 / 4111 / 5111 / 6111 ECWAY TECHNOLOGIES IEEE SOFTWARE | EMBEDDED | MECHANICAL | ROBOTICS PROJECTS DEVELOPMENT Visit: www.ecwaytechnologies.com | www.ecwayprojects.com Mail to: ecwaytechnologies@gmail.com DECLARATION I hereby declare that the project work entitled “Automatic 3-D Segmentation of Endocardial Border of the Left Ventricle From Ultrasound Images” Submitted to BHARATHIDASAN UNIVERSITY in partial fulfillment of the requirement for the award of the Degree of MASTER OF APPLIED ELECTRONICS is a record of original work done by me the guidance of Prof.A.Vinayagam M.Sc., M.Phil., M.E., to the best of my knowledge, the work reported here is not a part of any other thesis or work on the basis of which a degree or award was conferred on an earlier occasion to me or any other candidate. (Student Name) (Reg.No) Place: Date:
  • 4. OUR OFFICES @CHENNAI/ TRICHY / KARUR / ERODE / MADURAI / SALEM / COIMBATORE / BANGALORE / HYDRABAD CELL: +91 9894917187 | 875487 1111 / 2111 / 3111 / 4111 / 5111 / 6111 ECWAY TECHNOLOGIES IEEE SOFTWARE | EMBEDDED | MECHANICAL | ROBOTICS PROJECTS DEVELOPMENT Visit: www.ecwaytechnologies.com | www.ecwayprojects.com Mail to: ecwaytechnologies@gmail.com ACKNOWLEDGEMENT I am extremely glad to present my project “Automatic 3-D Segmentation of Endocardial Border of the Left Ventricle From Ultrasound Images” which is a part of my curriculum of third semester Master of Science in Computer science. I take this opportunity to express my sincere gratitude to those who helped me in bringing out this project work. I would like to express my Director,Dr. K. ANANDAN, M.A.(Eco.), M.Ed., M.Phil.,(Edn.), PGDCA., CGT., M.A.(Psy.)of who had given me an opportunity to undertake this project. I am highly indebted to Co-OrdinatorProf. Muniappan Department of Physics and thank from my deep heart for her valuable comments I received through my project. I wish to express my deep sense of gratitude to my guide Prof. A.Vinayagam M.Sc., M.Phil., M.E., for her immense help and encouragement for successful completion of this project. I also express my sincere thanks to the all the staff members of Computer science for their kind advice. And last, but not the least, I express my deep gratitude to my parents and friends for their encouragement and support throughout the project.
  • 5. OUR OFFICES @CHENNAI/ TRICHY / KARUR / ERODE / MADURAI / SALEM / COIMBATORE / BANGALORE / HYDRABAD CELL: +91 9894917187 | 875487 1111 / 2111 / 3111 / 4111 / 5111 / 6111 ECWAY TECHNOLOGIES IEEE SOFTWARE | EMBEDDED | MECHANICAL | ROBOTICS PROJECTS DEVELOPMENT Visit: www.ecwaytechnologies.com | www.ecwayprojects.com Mail to: ecwaytechnologies@gmail.com ABSTRACT: The segmentation of the left ventricle (LV) is an important task to assess the cardiac function in ultrasound images of the heart. This paper presents a novel methodology for the segmentation of the LV in three-dimensional (3-D) echocardiographic images based on the probabilistic data association filter (PDAF). The proposed methodology begins by initializing a 3- D deformable model either semiautomatically, with user input, or automatically, and it comprises the following feature hierarchical approach: 1) edge detection in the vicinity of the surface (lowlevel features); 2) edge grouping to obtain potential LV surface patches (mid-level features); and 3) patch filtering using a shapePDAF framework (high-level features). This method provides good performance accuracy in 20 echocardiographic volumes, and compares favorably with the state-of-the-art segmentation methodologies proposed in the recent literature.
  • 6. OUR OFFICES @CHENNAI/ TRICHY / KARUR / ERODE / MADURAI / SALEM / COIMBATORE / BANGALORE / HYDRABAD CELL: +91 9894917187 | 875487 1111 / 2111 / 3111 / 4111 / 5111 / 6111 ECWAY TECHNOLOGIES IEEE SOFTWARE | EMBEDDED | MECHANICAL | ROBOTICS PROJECTS DEVELOPMENT Visit: www.ecwaytechnologies.com | www.ecwayprojects.com Mail to: ecwaytechnologies@gmail.com INTRODUCTION: The automatic segmentation of the LV endocardium from ultrasound (US) images is a crucial step to characterize heart functionality, e.g., ejection fraction. In a clinical setup, there are several advantages involved in solving this problem in echocardiography. This includes the increase of patient throughput and the reduction of interuser variability in the LV delineation procedure. Although other imaging techniques, such as MRI and CT, provide images with better spatial resolution, echocardiography is still one of the most preferred modalities due to its temporal resolution, versatility, and low cost. However, automatic segmentation in echocardiography is not a simple task since it raises several challenges. First, the US images may contain more than one anatomical structure, meaning that it is necessary to correctly identify the region of interest (i.e., initialization procedure). Second, the borders of those structures may not always be present and they are often difficult to locate due to misleading edges and background noise. This problem is particularly accentuated in echocardiographic images, characterized by low signal-to-noise ratio, weak echoes, scattering, echo dropouts, and presence of speckle (i.e., cluttered background and outliers).Deformable models have been one of the most promising approaches to the segmentation in echocardiographic images. However, they still face two major issues. First, the initialization has a significant influence in the segmentation. This means that different initializations may provide different final shape estimates, introducing user-dependent bias. An automatic initialization solves this problem by guaranteeing that, for a specific volume, the final segmentations are consistent. Second, the presence of clutter hampers the accuracy of the segmentations. Most approaches do not have the ability to identify which image features (e.g., edge points) actually belong to the object of interest and which belong to the background noise or neighboring structures. This may cause the final segmentation to be poorer since erroneous edges have a negative impact in the adaptation of the deformable model. These problems have been the subject of intense research in the past decades and are the main concern of this paper. This paper proposes a new algorithm based on deformable models, tailored to perform the segmentation of the LV in threedimensional (3-D) echocardiographic images targeted to account for the difficulties mentioned previously, i.e., initialization and presence of outliers and cluttered background. To achieve this goal, we propose
  • 7. OUR OFFICES @CHENNAI/ TRICHY / KARUR / ERODE / MADURAI / SALEM / COIMBATORE / BANGALORE / HYDRABAD CELL: +91 9894917187 | 875487 1111 / 2111 / 3111 / 4111 / 5111 / 6111 ECWAY TECHNOLOGIES IEEE SOFTWARE | EMBEDDED | MECHANICAL | ROBOTICS PROJECTS DEVELOPMENT Visit: www.ecwaytechnologies.com | www.ecwayprojects.com Mail to: ecwaytechnologies@gmail.com 1) different initialization procedures along with 2) a probabilistic data association filter (PDAF) allowing for the robustness against the presence of clutter.
  • 8. OUR OFFICES @CHENNAI/ TRICHY / KARUR / ERODE / MADURAI / SALEM / COIMBATORE / BANGALORE / HYDRABAD CELL: +91 9894917187 | 875487 1111 / 2111 / 3111 / 4111 / 5111 / 6111 ECWAY TECHNOLOGIES IEEE SOFTWARE | EMBEDDED | MECHANICAL | ROBOTICS PROJECTS DEVELOPMENT Visit: www.ecwaytechnologies.com | www.ecwayprojects.com Mail to: ecwaytechnologies@gmail.com CONCLUSION: This paper presents a 3-D segmentation system that is able to segment the LV in echocardiographic volumes. The methodology is based on the use of a probabilistic data association filter, originally proposed in the context of control theory, to improve the detection of the ventricle boundary. The proposed segmentation system was coupled with an automatic initialization method to produce a fully automatic segmentation procedure that achieved competitive results when compared to a semiautomatic initialization based on space-carving. The results show that the proposed system performs well in a varied set of echocardiographic volumes. It also shows that the accuracy of the segmentations is competitive with other stateof-the-art works.
  • 9. OUR OFFICES @CHENNAI/ TRICHY / KARUR / ERODE / MADURAI / SALEM / COIMBATORE / BANGALORE / HYDRABAD CELL: +91 9894917187 | 875487 1111 / 2111 / 3111 / 4111 / 5111 / 6111 ECWAY TECHNOLOGIES IEEE SOFTWARE | EMBEDDED | MECHANICAL | ROBOTICS PROJECTS DEVELOPMENT Visit: www.ecwaytechnologies.com | www.ecwayprojects.com Mail to: ecwaytechnologies@gmail.com REFERENCES: [1] R. Juang, E. McVeigh, B. Hoffmann, D. Yuh, and P. Burlina, “Automatic segmentation of the left-ventricular cavity and atrium in 3D ultrasound using graph cuts and the radial symmetry transform,” in Proc. IEEE Int. Symp. Biomed. Imag., 2011, pp. 606–609. [2] F. Orderud and S. Rabben, “Real-time 3D segmentation of the left ventricle using deformable subdivision surfaces,” in Proc. Comput. Vis. Pattern Recog., 2008, pp. 1–8. [3] H. Liu and P. Shi, “State-space analysis of cardiac motion with biomechanical constraints,” IEEE Trans. Imag. Proc., vol. 16, no. 4, pp. 901–917, Apr. 2007. [4] X. Hang, N. Greenberg, and J. Thomas, “Left ventricle quantification in 3D echocardiography using a geometric deformable model,” Comput. Cardiol., pp. 649–652, 2005. [5] Y. Honggang, M. Pattichis, and M. Goens, “Robust segmentation and volumetric registration in a multi-view 3D freehand ultrasound reconstruction system,” in Proc. Asilomar Conf. Signals Syst. Comput., 2006, pp. 1058–6393. [6] V. Zagrodsky, V. Walimbe, C. Castro-Pareja, J. X. Qin, J.-M. Song, and R. Shekhar, “Registration-assisted segmentation of real-time 3D echocardiographic data using deformable models,” IEEE Trans. Med. Imag., vol. 24, no. 9, pp. 1089–1099, Sep. 2005. [7] L. Yang, B. Georgescu, Y. Zheng, P. Meer, and D. Comaniciu, “3D ultrasound tracking of the left ventricle using one-step forward prediction and data fusion of collaborative trackers,” in Proc. Comput. Vis. Pattern Recog., 2008, pp. 1–8.