9. 1. Download and open ChemDraw
2. Search by chemical/drug by name and insert structure
3. Click on A text box and type in name
4. Centre and/or click on lasso or marquee box to drag text
box and structure
5. Play about and learn the basics or watch any number of tutorial(s)
6. Copy/Scan and paste into Word
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24. Napoleon, J. V. ; Manheri, M. K. Direct Transformation of Baylis-
Hillman Acetates into N-Substituted Quinolones through an…
Oxidation Sequence. Synthesis 2011, 20, 3379-3388.
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27. Napoleon, J. V.; Manheri, M. K. Direct Transformation of
Baylis-Hillman Acetates into N-Substituted Quinolones
through an SN2′ → SNAr → (Δ3,4-Δ2,3 Shift) → Oxidation
Sequence. Synthesis 2011, 20, 3379-3388.
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31. Yachao, L. Chemical Synthesis Method for Norfloxacin. Patent
Application CN 107445892, 2017.
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36. New to this exercise:
• searching Reaxys chemistry and Espacenet patent databases
• consulting small molecule databases including PubChem, ChemSpider Drugs.com
• using commercial chemical manufacturing suppliers e.g. Sigma-Aldrich
• register, download and use ChemDraw chemical drawing software
• be better informed of biochemical research on antibiotics / antibacterial drug development,
their chemical properties, reactions, regulatory and scholarly information.
• define and comment on concepts fundamental to green chemistry.