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International Journal of Trend in Scientific Research and Development (IJTSRD)
Volume: 3 | Issue: 3 | Mar-Apr 2019 Available Online: www.ijtsrd.com e-ISSN: 2456 - 6470
@ IJTSRD | Unique Paper ID – IJTSRD23525 | Volume – 3 | Issue – 3 | Mar-Apr 2019 Page: 1785
A Review of Super Resolution and Tumor
Detection Techniques in Medical Imaging
Fathimath Safana C. K1, Sherin Mary Kuriakose2
1Student, 2Assistant Professor
1, 2Cochin College of Engineering and Technology, Valanchery, Kerala, India
How to cite this paper: Fathimath
Safana C. K | Sherin Mary Kuriakose "A
Review of Super Resolution and Tumor
Detection Techniques in Medical
Imaging" Published in International
Journal of Trend in Scientific Research
and Development
(ijtsrd), ISSN: 2456-
6470, Volume-3 |
Issue-3, April 2019,
pp.1785-1787, URL:
https://www.ijtsrd.c
om/papers/ijtsrd23
525.pdf
Copyright © 2019 by author(s) and
International Journal of Trend in
Scientific Research and Development
Journal. This is an Open Access article
distributed under
the terms of the
Creative Commons
Attribution License (CC BY 4.0)
(http://creativecommons.org/license
s/by/4.0)
ABSTRACT
Images with high resolution are desirable in many applications such as medical
imaging, video surveillance, astronomy etc. In medical imaging, images are
obtained for medical investigativepurposes andforprovidinginformation about
the anatomy, the physiologic and metabolic activities of the volume below the
skin. Medical imaging is an important diagnosis instrument to determine the
presence of certain diseases. Therefore increasing the image resolution should
significantly improve the diagnosis ability for correctivetreatment.Brain tumor
detection is used for identifying the tumor present in the Brain. MRIimageshelp
the doctors for identifying the Brain tumor size and shape of the tumor. The
purpose of this report to provide a survey of research related super resolution
and tumor detection methods.
KEYWORDS: Medical Imaging, super Resolution, Very Deep Super Resolution,
Tumor Detection, Deep Belief Network.
1. INTRODUCTION
Medical imaging also known as diagnostic imaging, through
this doctors look inside your body for clues about a medical
condition. A variety of machines and techniques can create
pictures of the structures and activities inside your body.
The type of imaging your doctor uses depends on your
symptoms and the part of your body being examined. They
include X rays, CT scans, Nuclear medicine scans and MRI
scans ultra sound. Many imaging tests are painless and easy.
Some require you to stay still for a long time inside a
machine. This can be uncomfortable. Certain tests involve
exposure to a small amountof radiation.Magneticresonance
imaging (MRI) is a medical imaging technique using radio
waves and magnetic fields to create detailed cross-sectional
images of internal organs and structures within the body.
Widely used in patient analysis and medical diagnosis, MRI
often reveals different information about bodily structures
than can be visualized using other imaging methods such as
X-ray, computed tomography (CT) or ultrasound. Medical
imaging is an important diagnosis instrument to determine
the presence of certain diseases. Therefore increasing the
image resolution should significantly improve the diagnosis
ability for corrective treatment. Furthermore, a better
resolution may substantially improve automatic detection
and image segmentation results. A tumor also known as
neoplasm is a growth in the abnormal tissue which can be
differentiated from the surrounding tissuebyits structure. A
tumor may lead to cancer, which is a major leading cause of
death and responsible for around 13% of all deaths world-
wide. Cancer incidence rate is growing at an alarmingrate in
the world. Great knowledge and experience on radiology are
required for accurate tumor detection in medical imaging.
Automation of tumor detection is required because there
might be a shortage of skilled radiologists at a time of great
need.
2. OVERVIEW OF SUPER RESOLUTION
The objective of image super-resolution is to enhance or
increase the resolution of a given low-resolution image into
high resolution image through some techniques like up-
sampling, de-blurring, de-noising, etc. In order to restore an
image into a high-resolution image correctly, it is necessary
to infer high frequency components of a low-resolution
image. Image super-resolution is important in many
applications of multimedia, such as playing a video on a
higher-resolution screen. Due to some technical limitations
in imaging devices and systems, like, the presence of optical
distortions and lens blur, insufficient sensor sampling
density and aliasing, motion blur due to low shutter speed,
the presence of noise due to sensor limitations and lossy
coding, super-resolution technique is actually needed.
IJTSRD23525
International Journal of Trend in Scientific Research and Development (IJTSRD) @ www.ijtsrd.com eISSN: 2456-6470
@ IJTSRD | Unique Paper ID – IJTSRD23525 | Volume – 3 | Issue – 3 | Mar-Apr 2019 Page: 1786
2.1 Methods Related To Super Resolution.
In this paper, we make a review on some well-known
approaches or techniques related to image superresolution.
From all the super resolution methods it can be categorized
into three types [1]. Interpolation based, Reconstruction
based and Example based. Interpolation based super
resolution. Simplest way to provide super-resolution is to
apply interpolation on the sampled visual data acquired
from the sensor. It is one of the early super-resolution
algorithms based on resampling (a mathematical technique
used to create a new version of the image with a different
width and/or height in pixels). This approach, for example,
which is present in digital cameras via the digital zoom,
ultimately relies on the operations based on linear filtering.
[2] This technique has advantage of less computational
complexity due to its simplicity and also real-time
applications are possible. The reconstruction-based super-
resolution approaches [3] apply various smoothness priors
and impose the constraint that when properly down
sampled, the high-resolution image should reproduce the
original low-resolutionimage.Inexamplebased methods[4]
there having a database of high-resolution images
corresponding to the low-resolution examples that best
resembles or matches the two parts of given image and
reconstruct the correspondinghigh-resolutionversionofthe
given image with the technique of selecting, editing and
piecing together.
2.2 Estimation Parameters of Super Resolution.
The performance evaluation metrics of super resolution are
peak signal to noise ratio (PSNR), the structural similarity
and mean square error [5]. PSNR is the ratio between the
maximum possible power of a signal and the power of
corrupting noise thataffects thefidelityofits representation.
Because many signalshave a verywide dynamicrange,PSNR
is usually expressedinterms ofthe logarithmic decibel scale.
Structural similarity is the index is a method for predicting
the perceived quality of digital television and cinematic
pictures, as well as other kinds of digital images and videos.
Mean square error is the measures the average of the
squares of the errors that is, the average squared difference
between the estimated values and what is estimated.
3. OVERVIEW OF TUMOR DETECTION
Nowadays, brain tumor has become one of the main causes
for increasing mortality among children and adults. This
facts increase the importance of the researchesonthetumor
detection and this will present theopportunityfordoctorsto
help save lives by detecting the disease earlier and perform
necessary actions. Varieties of image processing techniques
are available to be applied on various imaging modalitiesfor
tumor detection that will detect certain features of the
tumors such as the shape, border, calcification and texture.
These features will make the detection processes more
accurate and easier as there are some standard
characteristics of each feature for a specific tumor
3.1 Methods Related To Tumor Detection
Deep learning [6] is a machine learning technique that
teaches computers to do what comes naturally to humans:
learn by example. The second common cancer is Breast
cancer in the women population. Detection of breast cancer
[7] in early stage increases chances for treatment.
Mammography is the best screening instrument that uses
low dose X-rays to find tumors in a breast image.
Mammography images sufferfromlowqualityand contrast. ,
images are preprocessed by morphological filters. ROTs in
images are determined by segmentation. Then, Extracted
features fed to K -NN. Preprocessing reduces the glandular
tissues and noises. In this stage, use two types of
morphological filters, theopeningfilter and closingfilter that
are used in the mammography gray images. ThenExtraction
of ROls to segment regions of tumor in each image. In this
paper [8] data mining methods are used for classification of
MRI images. A new hybrid technique based on the support
vector machine (SVM) and fuzzy c-means for brain tumor
classification is proposed [9]. The purposed algorithm is a
combination of support vector machine (SVM) and fuzzy c-
means, a hybrid technique for prediction of braintumor. The
enhanced images are fed to a pre-trained convolutional
neural network (CNN) which is a member of deep learning
models. The CNN classifier, [10] which is trained by large
number of training samples, distinguishes between
melanoma and benign cases.
3.2 Estimation Parameters of Tumor Detection
Accuracy, sensitivity and specificity are main parameters to
estimate the tumor detection. These parameters are
calculated through some terms like TP, be the True Positive
which is number of pixels correctly identified astumor.FP is
False Positive; it is number of pixels incorrectly identified as
tumor. Similarly TN the True Negative is number of pixels
correctly identified as healthy and FN is False Negative is a
number of pixels incorrectly identified as healthy.
4. CONCLUSION
This paper described the various super resolution methods
and different tumor detection methods. The main estimation
parameters of super resolution are peak signal tonoiseratio,
structural similarity and mean square error. Accuracy,
sensitivity and specificity are the main parameters of tumor
detection techniques. Medical imaging is an important
diagnosis instrument to determine the presence of certain
diseases. Therefore increasing the image resolution should
significantly improve the diagnosis ability for corrective
treatment. Furthermore, a better resolution may
substantially improve automatic detection and image
segmentation results.
5. REFERENCES
[1]. Nirali Harsoda, Namarata Joshi. “A Review on Image
Super Resolution Techniques”. InternationalJournalof
Engineering Research and Technology (IJERT), Vol. 3,
Issue 2, February 2014.
[2]. Jonathan Sachs. “Image Resampling”. Digital Light
andColor, 2011.
[3]. W. S. Tam, C. W. Kok, W. C. Siu. “A modified edge
directed interpolation for images”.JournalofElectronic
Imaging, 19(1), 013011:1–20, 2010.
[4]. W. T. Freeman, T. R. Jones, E. C. Pasztor. “Example-
based super-resolution”. IEEE Computer Graphics and
Applications, pp. 56 – 65, Vol. 22, Issue 2, 2002.
[5]. X. J. Kim, J. Kwon Lee, and K. Mu Lee, “Accurate image
super-resolution using very deep convolutional
networks,” in Proceedings of the IEEE Conference on
Computer Vision and Pattern Recognition, pp. 1646–
1654. 2016.
[6]. Y. LeCun, Y. Bengio, and G. Hinton, “Deep learning,”
Nature, vol. 521, no. 7553, pp. 436–444, 2015
International Journal of Trend in Scientific Research and Development (IJTSRD) @ www.ijtsrd.com eISSN: 2456-6470
@ IJTSRD | Unique Paper ID – IJTSRD23525 | Volume – 3 | Issue – 3 | Mar-Apr 2019 Page: 1787
[7]. Fatemeh shirazi, Esmat rashedi, “Feature Weighting
For Cancer Tumor DetectionIn MammographyImages
Using Gravitational Search Algorithm”, 6th
International Conference on Computer andKnowledge
Engineering (ICCKE 2016), October 20-21, 2016
[8]. Parveen, Amritpal singh, “Detection of Brain Tumor in
MRI Images, Using Combination of Fuzzy C-Means and
SVM,” 2nd International Conference on Signal
Processing and Integrated Network s2015
[9]. E. Nasr-Esfahani, S. Samavi, N. Karimi, S.M.R.
Soroushmehr, M.H. Jafari, K. Ward, K. Najarian
“Melanoma Detection by Analysis of Clinical Images
Using Convolutional Neural Network, IEEE, pp. 770–
778.
[10]. Sergio Pereira, Adriano Pinto, Victor Alves and Carlos
A. Silva, “Brain Tumor Segmentation using
Convolutional Neural Networks in MRI Images,” IEEE
Transactions on Medical Imaging, vol. 49, no. 11, pp.
1875–1883, 2016

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A Review of Super Resolution and Tumor Detection Techniques in Medical Imaging

  • 1. International Journal of Trend in Scientific Research and Development (IJTSRD) Volume: 3 | Issue: 3 | Mar-Apr 2019 Available Online: www.ijtsrd.com e-ISSN: 2456 - 6470 @ IJTSRD | Unique Paper ID – IJTSRD23525 | Volume – 3 | Issue – 3 | Mar-Apr 2019 Page: 1785 A Review of Super Resolution and Tumor Detection Techniques in Medical Imaging Fathimath Safana C. K1, Sherin Mary Kuriakose2 1Student, 2Assistant Professor 1, 2Cochin College of Engineering and Technology, Valanchery, Kerala, India How to cite this paper: Fathimath Safana C. K | Sherin Mary Kuriakose "A Review of Super Resolution and Tumor Detection Techniques in Medical Imaging" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456- 6470, Volume-3 | Issue-3, April 2019, pp.1785-1787, URL: https://www.ijtsrd.c om/papers/ijtsrd23 525.pdf Copyright © 2019 by author(s) and International Journal of Trend in Scientific Research and Development Journal. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (http://creativecommons.org/license s/by/4.0) ABSTRACT Images with high resolution are desirable in many applications such as medical imaging, video surveillance, astronomy etc. In medical imaging, images are obtained for medical investigativepurposes andforprovidinginformation about the anatomy, the physiologic and metabolic activities of the volume below the skin. Medical imaging is an important diagnosis instrument to determine the presence of certain diseases. Therefore increasing the image resolution should significantly improve the diagnosis ability for correctivetreatment.Brain tumor detection is used for identifying the tumor present in the Brain. MRIimageshelp the doctors for identifying the Brain tumor size and shape of the tumor. The purpose of this report to provide a survey of research related super resolution and tumor detection methods. KEYWORDS: Medical Imaging, super Resolution, Very Deep Super Resolution, Tumor Detection, Deep Belief Network. 1. INTRODUCTION Medical imaging also known as diagnostic imaging, through this doctors look inside your body for clues about a medical condition. A variety of machines and techniques can create pictures of the structures and activities inside your body. The type of imaging your doctor uses depends on your symptoms and the part of your body being examined. They include X rays, CT scans, Nuclear medicine scans and MRI scans ultra sound. Many imaging tests are painless and easy. Some require you to stay still for a long time inside a machine. This can be uncomfortable. Certain tests involve exposure to a small amountof radiation.Magneticresonance imaging (MRI) is a medical imaging technique using radio waves and magnetic fields to create detailed cross-sectional images of internal organs and structures within the body. Widely used in patient analysis and medical diagnosis, MRI often reveals different information about bodily structures than can be visualized using other imaging methods such as X-ray, computed tomography (CT) or ultrasound. Medical imaging is an important diagnosis instrument to determine the presence of certain diseases. Therefore increasing the image resolution should significantly improve the diagnosis ability for corrective treatment. Furthermore, a better resolution may substantially improve automatic detection and image segmentation results. A tumor also known as neoplasm is a growth in the abnormal tissue which can be differentiated from the surrounding tissuebyits structure. A tumor may lead to cancer, which is a major leading cause of death and responsible for around 13% of all deaths world- wide. Cancer incidence rate is growing at an alarmingrate in the world. Great knowledge and experience on radiology are required for accurate tumor detection in medical imaging. Automation of tumor detection is required because there might be a shortage of skilled radiologists at a time of great need. 2. OVERVIEW OF SUPER RESOLUTION The objective of image super-resolution is to enhance or increase the resolution of a given low-resolution image into high resolution image through some techniques like up- sampling, de-blurring, de-noising, etc. In order to restore an image into a high-resolution image correctly, it is necessary to infer high frequency components of a low-resolution image. Image super-resolution is important in many applications of multimedia, such as playing a video on a higher-resolution screen. Due to some technical limitations in imaging devices and systems, like, the presence of optical distortions and lens blur, insufficient sensor sampling density and aliasing, motion blur due to low shutter speed, the presence of noise due to sensor limitations and lossy coding, super-resolution technique is actually needed. IJTSRD23525
  • 2. International Journal of Trend in Scientific Research and Development (IJTSRD) @ www.ijtsrd.com eISSN: 2456-6470 @ IJTSRD | Unique Paper ID – IJTSRD23525 | Volume – 3 | Issue – 3 | Mar-Apr 2019 Page: 1786 2.1 Methods Related To Super Resolution. In this paper, we make a review on some well-known approaches or techniques related to image superresolution. From all the super resolution methods it can be categorized into three types [1]. Interpolation based, Reconstruction based and Example based. Interpolation based super resolution. Simplest way to provide super-resolution is to apply interpolation on the sampled visual data acquired from the sensor. It is one of the early super-resolution algorithms based on resampling (a mathematical technique used to create a new version of the image with a different width and/or height in pixels). This approach, for example, which is present in digital cameras via the digital zoom, ultimately relies on the operations based on linear filtering. [2] This technique has advantage of less computational complexity due to its simplicity and also real-time applications are possible. The reconstruction-based super- resolution approaches [3] apply various smoothness priors and impose the constraint that when properly down sampled, the high-resolution image should reproduce the original low-resolutionimage.Inexamplebased methods[4] there having a database of high-resolution images corresponding to the low-resolution examples that best resembles or matches the two parts of given image and reconstruct the correspondinghigh-resolutionversionofthe given image with the technique of selecting, editing and piecing together. 2.2 Estimation Parameters of Super Resolution. The performance evaluation metrics of super resolution are peak signal to noise ratio (PSNR), the structural similarity and mean square error [5]. PSNR is the ratio between the maximum possible power of a signal and the power of corrupting noise thataffects thefidelityofits representation. Because many signalshave a verywide dynamicrange,PSNR is usually expressedinterms ofthe logarithmic decibel scale. Structural similarity is the index is a method for predicting the perceived quality of digital television and cinematic pictures, as well as other kinds of digital images and videos. Mean square error is the measures the average of the squares of the errors that is, the average squared difference between the estimated values and what is estimated. 3. OVERVIEW OF TUMOR DETECTION Nowadays, brain tumor has become one of the main causes for increasing mortality among children and adults. This facts increase the importance of the researchesonthetumor detection and this will present theopportunityfordoctorsto help save lives by detecting the disease earlier and perform necessary actions. Varieties of image processing techniques are available to be applied on various imaging modalitiesfor tumor detection that will detect certain features of the tumors such as the shape, border, calcification and texture. These features will make the detection processes more accurate and easier as there are some standard characteristics of each feature for a specific tumor 3.1 Methods Related To Tumor Detection Deep learning [6] is a machine learning technique that teaches computers to do what comes naturally to humans: learn by example. The second common cancer is Breast cancer in the women population. Detection of breast cancer [7] in early stage increases chances for treatment. Mammography is the best screening instrument that uses low dose X-rays to find tumors in a breast image. Mammography images sufferfromlowqualityand contrast. , images are preprocessed by morphological filters. ROTs in images are determined by segmentation. Then, Extracted features fed to K -NN. Preprocessing reduces the glandular tissues and noises. In this stage, use two types of morphological filters, theopeningfilter and closingfilter that are used in the mammography gray images. ThenExtraction of ROls to segment regions of tumor in each image. In this paper [8] data mining methods are used for classification of MRI images. A new hybrid technique based on the support vector machine (SVM) and fuzzy c-means for brain tumor classification is proposed [9]. The purposed algorithm is a combination of support vector machine (SVM) and fuzzy c- means, a hybrid technique for prediction of braintumor. The enhanced images are fed to a pre-trained convolutional neural network (CNN) which is a member of deep learning models. The CNN classifier, [10] which is trained by large number of training samples, distinguishes between melanoma and benign cases. 3.2 Estimation Parameters of Tumor Detection Accuracy, sensitivity and specificity are main parameters to estimate the tumor detection. These parameters are calculated through some terms like TP, be the True Positive which is number of pixels correctly identified astumor.FP is False Positive; it is number of pixels incorrectly identified as tumor. Similarly TN the True Negative is number of pixels correctly identified as healthy and FN is False Negative is a number of pixels incorrectly identified as healthy. 4. CONCLUSION This paper described the various super resolution methods and different tumor detection methods. The main estimation parameters of super resolution are peak signal tonoiseratio, structural similarity and mean square error. Accuracy, sensitivity and specificity are the main parameters of tumor detection techniques. Medical imaging is an important diagnosis instrument to determine the presence of certain diseases. Therefore increasing the image resolution should significantly improve the diagnosis ability for corrective treatment. Furthermore, a better resolution may substantially improve automatic detection and image segmentation results. 5. REFERENCES [1]. Nirali Harsoda, Namarata Joshi. “A Review on Image Super Resolution Techniques”. InternationalJournalof Engineering Research and Technology (IJERT), Vol. 3, Issue 2, February 2014. [2]. Jonathan Sachs. “Image Resampling”. Digital Light andColor, 2011. [3]. W. S. Tam, C. W. Kok, W. C. Siu. “A modified edge directed interpolation for images”.JournalofElectronic Imaging, 19(1), 013011:1–20, 2010. [4]. W. T. Freeman, T. R. Jones, E. C. Pasztor. “Example- based super-resolution”. IEEE Computer Graphics and Applications, pp. 56 – 65, Vol. 22, Issue 2, 2002. [5]. X. J. Kim, J. Kwon Lee, and K. Mu Lee, “Accurate image super-resolution using very deep convolutional networks,” in Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 1646– 1654. 2016. [6]. Y. LeCun, Y. Bengio, and G. Hinton, “Deep learning,” Nature, vol. 521, no. 7553, pp. 436–444, 2015
  • 3. International Journal of Trend in Scientific Research and Development (IJTSRD) @ www.ijtsrd.com eISSN: 2456-6470 @ IJTSRD | Unique Paper ID – IJTSRD23525 | Volume – 3 | Issue – 3 | Mar-Apr 2019 Page: 1787 [7]. Fatemeh shirazi, Esmat rashedi, “Feature Weighting For Cancer Tumor DetectionIn MammographyImages Using Gravitational Search Algorithm”, 6th International Conference on Computer andKnowledge Engineering (ICCKE 2016), October 20-21, 2016 [8]. Parveen, Amritpal singh, “Detection of Brain Tumor in MRI Images, Using Combination of Fuzzy C-Means and SVM,” 2nd International Conference on Signal Processing and Integrated Network s2015 [9]. E. Nasr-Esfahani, S. Samavi, N. Karimi, S.M.R. Soroushmehr, M.H. Jafari, K. Ward, K. Najarian “Melanoma Detection by Analysis of Clinical Images Using Convolutional Neural Network, IEEE, pp. 770– 778. [10]. Sergio Pereira, Adriano Pinto, Victor Alves and Carlos A. Silva, “Brain Tumor Segmentation using Convolutional Neural Networks in MRI Images,” IEEE Transactions on Medical Imaging, vol. 49, no. 11, pp. 1875–1883, 2016