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Francesco Procaccio - Italy - Tuesday 29 - Donor Risk
- 1. Critical points in DBD : malignancy screening in ICU F. Procaccio, M. Liviero Casartelli, L Zampicinini Neuro Intensive Care Unit University City Hospital Verona - Italy
- 7. If TCs follow adequate guidelines the risk of transmission is really low Spain
- 8. National guidelines + second opinion on call low risk of cancer transmission Italy
- 9. Potential Organ Donor Evaluation All BDs should be evaluated. Screening for trasmissible diseases. National guidelines and risk classification
- 10. History of malignancy is not always a contraindication to donation It is essential to obtain all the data on the tumour Germany
- 11. NOTIFY
- 14. Malignancy screening in Potential Organ Donors NICU Verona Italy 2007 2010 * males 52% 146 BD declarations 106 cases with consent N° N ° % Tracheobroncoscopy 30 30 28 TOTAL-BODY CTcsan 29 23 22 Abdomen Echography 133 105 99 Prostate exam+echo* 48 43 80 Breast examination* 60 54 98 Breast echography* 11 11 20 Dermatological examination 114 98 93
- 15. < 60 years > 60 years Biopsy vs Age vs Utilized Organs
- 16. N ecroscopy in 59 out of 96 actual donors Not expected lesions UTILIZED Organs FOLLOW-UP (1-3 years) 1 breast cancer Liver Lung Negative Dead (sepsis) 1 prostate Gleason 5 (standard risk) Liver Kidney Kidney Negative Negative Negative 1 Hepatocarcinoma Liver Heart negative Negative 1 Hepatocarcinoma no
- 17. Malignancy in 3 recipients brain pancreas bladder No malignancies Follow-up of 139 recipients from 59 donors with necroscopy Negative Necroscopy Positive Necroscopy 2007-2010 NICU Verona Italy 151 organs – 132 recipients 7 organs – 7 recipients
- 20. OPO Coordination Location of Procurement Coordination
- 21. Organ donation Transplantation ICUs Tx Centers Severe brain lesion Management Pre-post Tx treatment Knowledge Procedures Organization Staff Network Quality control Resources Support Champions Hospital Procurement Coordinator National & Regional Centers – Second Opinion A Model of Hospital coordination in progress Infectious Diseases Radiology Follow-up Pathology Donor evaluation Operative Transplant Medicine Dpt
Notas del editor
- Allegato n.7 Presentazione n.6 &quot;Selezione donatore secondo Linee Guida Nazionali&quot;