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2. Kramer (1974) defined cyst as “a pathologic
cavity having fluid, semi fluid or gaseous
contents that are not created by the
accumulation of pus; frequently but not
always, is it lined by epithelium”.
Killey and Kay (1966)
Cyst is that entity constitutes an epithelium
lined sac filled with fluid or semi fluid
material
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3. DEFINITION:
Tumour is defined as lesion resulting
from the autonomous or relatively
autonomous abnormal growth of cells which
persists after the initiating stimulus has been
removed i,e cell growth is escaped from
normal regulatory mechanism.
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4. A central cavity – usually
contains fluid or semisolid
material such as cellular
debris, keratin or mucous
An epithelial lining –
keratinized or
nonkeratinized stratified
squamous, pseudostratified,
columnar or cuboidal
epithelium
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5. An outer wall (capsule) –
composed of Connective
tissue containing fibroblasts
& blood vessels
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6. Progressively enlarging
Painless unless infected
Intrabony cyst cause expansion of buccal cortical plate
Teeth may be displaced rather than resorption
Soft tissue cyst – fluctuant on palpation
Radiographic view of intra bony cyst –unilocular or
multilocular radiolucency(OKC)
Small cysts – in cancellous bone – round to ovoid contour with
smooth sclerotic margins
Scalloped margins – unequal growth activity
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9. EFFCTS ON
SURROUNDIN
G
STRUCTURES
•CYSTS GROW
SLOWLY
•DISPLACEMENT
AND RESORPTION
OF TEETH
•IT CAN EXPAND
MANDIBLE
,USUALLY IN
SMOOTH CURVED
MANNER AND
CHANGE THE B/L
CORTICAL PLATES
INTO THIN
CORTICAL
BOUNDARY
•IT MAY DISPLACE
IAC/INVAGINATE
M.ANTRUM.
•PRESSURE ON
NEIGNBOURING
STRUCTURES
RESULTING IN
DISP. OF
TEETH/BONY
CORTICES.
•GROWTH IS
SLOW
,OUTERCORTEX
REMODELING
TAKES PLACE,
•RESISTS
PERFORATION
•ROOT
RESORPTION IS
MORE
COMMON.
•MAINLY
DESTROYS THE
SURROUNDING
ALV.BONE,SO
TEETH APPEARS
TO BE FLOATIG
IN SPACE.
•IRREGULAR
WIDENING OF
PDL SPACE
•LACK OF
LAMINADURA
•SOME
TUMOURS
STIMULATE
PERIOSTEAL
NEW BONE
FORMATION.
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10. Cyst initiation
Enlargement or expansion of the cyst
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11. Cells of odontogenic epithelium are predetermined. Eg:
Remnants of dental lamina.
Reduced enamel organ.
Cell rests of malassez.
Extension of basal cells from overlying
epithelium.
Irritants from the tooth
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12. Epithelial proliferation to form sphere of cells- diffusion of
oxygen and nutrients insufficient – death of central cells or
desquamation of the central cells
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13. Attraction of fluid into the cyst cavity
Retention of the fluid with in the cavity
Production of raised internal hydrostatic pressure
Resorption of surrounding bone with an increase in
the size of cavity
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14. Harries classified the theories of cyst enlargement
in the following manner
Mural growth
- Peripheral cell division
- Accumulation of cellular content
Hydrostatic enlargement
- Secretion
- Transudation and exudation
- Dialysis
Bone resorbing factor
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16. CLASSIFICATION OF CYSTS
CYSTS
Cysts of the jaws
Cysts associated with
maxillary antrum
Cysts of the soft
tissues
Epithelial cysts Nonepithelial cysts
Odontogenic cysts Non odontogenic cysts
Developmental Inflammatory Shearswww.indiandentalacademy.com
18. 1. Naso palatine cyst (incisive canal)
2. Naso labial (naso alveolar) cyst
3. Mid palatal raphe cyst of infants
4. Median palatine, median alveolar cyst & median mandibular
cyst
5. Globulo maxillary cyst
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19. Simple bone cyst (traumatic, simple, hemorrhagic bone
cyst)
Aneurysmal bone cyst
CYSTS ASSOCIATED WITH MAXILLARY ANTRUM
Benign mucosal cyst of the maxillary antrum
Post operative maxillary cyst (surgically ciliated cyst of
the maxilla
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27. Synonyms: Follicular cyst or Pericoronal cyst
Definition:
- an odontogenic cyst that surrounds the crown
of an impacted tooth; caused by fluid accumulation
between the reduced enamel epithelium and the enamel
surface, resulting in a cyst in which the
crown is located within the lumen
and roots outside
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28. Age – 2nd and 3rd decades.
Sex – males > females; 1.6:1
Race – whites > Blacks; 4:1
Frequency – 15-20%
Site – Mandibular 3rd molar.
Shape: Round or oval.
May also be found enclosing a complex compound
odontoma or involving a supernumerary tooth.
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29. Location:
Associated with crown
of unerupted and displaced
tooth, typically mand/max
3rd molar teeth where
eruption is impeded.
Size: variable,
Shape: — Round or oval,
typically enveloping
the crown symmetrically
— 3 varieties are described
depending on the
cyst/crown relationship:
(i) central
(ii) lateral
(iii) circumferential.
Outline
Smooth
Well defined
Often well corticated.
Radiodensity: Uniformly
radiolucent.www.indiandentalacademy.com
30. Effects on surrounding structures.
displace and resorb adjacent teeth
The floor of the maxillary antrum may be displaced
as the cyst invaginates the antrum,
may displace the inferior alveolar nerve canal in an
inferior direction.
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33. An eruption cyst is the soft tissue analogue of a dentigerous cyst
Definition : It is an odontogenic
cyst with the histologic features
of a dentigerous cyst that
surrounds a tooth’s crown that
has erupted through bone but
not soft tissue and is clinically
visible as a soft fluctuant mass on the alveolar ridges.
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34. Age- 1 month to 12 years
with a mean of 4.4 years.
Site- Deciduous and permanent
teeth.
Mandibular central primary
incisors and cuspid most
frequently involved.
Sex – Boys, ratio of 2:1
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38. It is a cyst derived from the remnants(rests) of the dental
lamina, with a biological behaviour similar to a benign
neoplasm,
Definition:
OKC IS now designated by the WHO as a keratocystic
odontogenic tumour and is defined as a “ benign uni or
multicystic, intraosseous tumour of odontogenic origin,
with a charecteristic lining of parakeratinized stratified
squamous epithelium and potential for aggressive,
infiltrative behaviour”
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39. Age: Second and third
decades of life.
Sex: Male to female ratio
1.46:1.
Site: Mandible(60 -80%).
Maxilla: third molar area-
cuspid region.
Shape : Oval
mediolateral
expansion.
Frequency: 11% of all cysts.
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40. • location: — Posterior
body/angle
Anterior maxilla in
canine region.
• Size: Variable.
• Shape: — Oval,
extending along the body
of the mandible with little
mediolateral expansion
Outline: — Smooth
— Well defined
— Often well corticated.
• Radiodensity. Uniformly
radiolucent.
• Effects: — Adjacent teeth
— minimal displacement,
rarely resorbed
— Extensive expansion
within the cancellous
bone.
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43. BASAL CELL NEVI SYNDROME
Hereditary, autosomal dominant trait characterized
by several developmental defects and a
predisposition to cancer.
The syndrome was first delineated by Gorlin and
Goltz.
C/F
Age - 5 and 30 years of age.
Sex - equal frequency
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44. Major criteria Minor criteria
Multiple KOT Bcc
Palmar and/or
plantar pitting
Dystrophic
Calcification of
flax cerebi
Bifid rib Medulloblastoma
Cleft palate Temporal and
temporoparietal
bossing
Mild
mandibular
prognathism
High arched
eyebrows and
palates
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46. Also called Dental
Lamina Cyst of the
Newborn.
Often multiple and
occasionally solitary
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47. Usually seen in infants and
rarely seen over 3 years of
age.
More common in 3 month old child.
Those in anterior portion of the jaws were
usually displaced lingually with respect to
deciduous incisors and cuspids.
Those in posterior portion of the jaw were found
occlusal to the crown of the molars
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48. Clinically, cyst appears as
a discrete white swellings
of the alveolar ridge.
Due to internal pressure it
appears blanched .
These lesions appears to
be asymptomatic and do
not seem to produce
discomfort in the infants.
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49. Epstein’s pearls are cystic keratin filled nodules
found along the mid palatine raphe, probably
derived from entrapped epithelial remnants
along the line of fusion.
Bohn’s nodules are keratin filled cysts scattered
over the palate, most numerous along the
junction of hard and soft palate and apparently
derived from palatal salivary gland structures.
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50. Radiographic features:
No significant radiographic features.
Treatment:
No treatment required
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51. A small developmental
odontogenic cyst of the
gingival soft tissue derived
from rests of the dental
lamina, containing a
lining of embryonic
epithelium of cuboidal
cells and distinctive focal
thickenings similar to the
lateral periodontal cyst.
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52. Age: 5th to 6th decade of
life
Sex: equal proportions
Site: Mandible.
slowly enlarging,
painless swelling,
usually less than 1 cm in
diameter.
Free or attached
gingiva, some occur in
the gingival papilla itself.
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53. No radiological changes in the underlying bone.
May erode the outer cortex of the mandible, especially on the
buccal side.
When it is present high near interdental papilla, there is
saucerization of the intercrestal bone is seen
Differential diagnosis:
Lateral periodontal cyst
Treatment:
surgical excision
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54. It is a slow growing,
nonexpansile
developmental
odontogenic cyst derived
from one or more rests of
the dental lamina,
It is of development origin
arising from cystic
degeneration of clear cells
of the dental lamina
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55. Age: 5th to 6th decade.
Sex: male
Site: Mandible,
cuspid and bicuspid
region or upper lateral incisor.
Size: less than 1 cm.
Associated tooth is vital.
Discovered during routine r/g examination.
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57. Site: Lateral surface of the
roots of vital teeth
in the lowercanine/
premolar region or upper
lateral incisor region.
Size: Small, less than 1 cm
in diameter.
Shape: — Monolocular,
very occasionally
Multilocular
Round
Outline: Smooth
— Well defined and
corticated.
Radiodensity: Uniformly
radiolucent.
Effects: — Adjacent teeth
— displaced if cyst
becomes large, rarely
resorbed
— Buccal expansion if
large
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59. Keratinizing and /or calcifying epithelial odontogenic
cyst
Gorlin cyst
Cystic Keratinizing tumor.
First explained by Gorlin et al in 1962.
In the latest WHO publication on odontogenic tumors,
COC was classified as a benign odontogenic tumor and
was renamed calcifying cystic odontogenic tumors.
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60. Age: 10 to 24 years. Common in children and
young adults.
Sex – female .
Site - Maxilla is more commonly affected.
lesions occurring before the age of 41 affects
maxilla and in older age mandible is more
commonly affected
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61. Unerupted teeth
Swelling - frequent
complaint.
Usually not associated
with pain.
Intra-osseous lesions
produce a hard bony
expansion .
Cyst may perforate the
cortical plate and extend
into the soft tissues
Extra osseous lesions tend
to be pink to red,
circumscribed elevated
masses measuring up to
4cm in diameter www.indiandentalacademy.com
62. Location : mostly in
maxilla ant. To 1st molar
• Shape and outline: A
circumscribed, smooth,
well defined unilocular
and may be multilocular
radiolucent lesion. It is
often corticated.
• Internal structure :
radiolucent
Small foci of calcifications
(salt & pepper)
Irregular calcified bodies of
varying sizes
Solid amorphous material
(odontome
•Associated with surrounding
structures:Associated with
unerupted teeth.
•Adjacent tooth root
displacement or resorbed roots
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64. Synonyms : sialo odontogenic cyst,
muco epidermoid Odontogenic cyst
The second edition of the WHO histological classification of
odontogenic tumors in 1992 recognised it as “ a cyst arising in
the tooth- bearing areas of the jaws and charecterized by an
epithelial lining with cuboidal or columnar cells both at the
surface and lining crypts or cyst-like spaces within the
thickness of the epithelium.”
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65. Age- 6th decade
Sex- male predilection.
Site- Mandible
Common site affected
is anterior mandible.
Usually extends
posteriorly to premolars
bilaterally.
The lesions showed slow
progressive growth,
painless and locally
destructive
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66. Site : more common in
mandible mostly ant
region and in maxilla
commonly in globulo
maxillary region
Periphery and shape :
corticated boundary that
may be smooth/scalloped
Internal structure :
unilocular and
multilocular appearances
Effects on surrounding
structures : expansion of
outer cortical plates of the
jaws with regions of
perforation through
cortex
Displacement of the teeth
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68. Treatment:
treatment should be conservative with a careful
dissection of the margins in order to avoid recurrences.
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69. It is a developmental cyst of
odontogenic epithelial origin
considered as a rare
multilocular variety of lateral
periodontal cyst (WHO 1992).
It is an unusual type of cyst.
First reported by Weathers
and Waldron in 1973.
It is a polycystic variant of the
lateral periodontal cyst
developing through cystic
transform of multiple islands
of dental lamina rests.
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70. It is named for its
characteristic multilocular
appearance which
resembles a “ cluster of
grapes”.
The cystic lesion site is in
the periodontal space of
vital teeth.
lateral to the root of a vital
mandibular cuspid or
premolar tooth.
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71. Location:lateral to the
root of a vital
mandibular cuspid or
premolar tooth.
Size: The lesion is usually
small in diameter
Shape and outline: well
circumscribed.
Sometimes, the border is
surrounded by a thin
layer of sclerotic bone
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73. Synonyms : radicular cysts, apical periodontal cyst , root
end cyst
Periapical cyst is the most common odontogenic cyst
Periapical cyst is the second most common pathologic
periapical radiolucency
The apical granuloma is the most common
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74. Age Occur at any age but 3rd decade is more commonly affected
Etiology: infected tooth
Site Maxilla is more commonly affected as compared to
mandible
In maxilla most common site is anterior region
In mandible most common site is molars
Majority of cyst are asymptomatic
Tooth is seldom painful or even sensitive to percussion
On long standing cases they may develop into abscess and then
into celluliis/draining fistulas
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76. Site:
Apex of any non-vital
tooth, particularly upper
lateral incisors.
• Size:
1.5-3 cm in diameter
Shape: — Round
— Monolocular.
Outline: — Smooth
—Well defined
Well corticated if long-
standing(unless infected)
and continuous with the
lamina dura of the associated
tooth.
• Radio density: Uniformly
radiolucent.
• Effects: — Adjacent teeth
— displaced, rarely resorbed
— Buccal expansion —
Displacement of the antrum
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79. Differential diagnosis
Periapical granuloma
Apical scar/surgical defect
Lateral periodontal cyst
Periapical cemento
osseous dysplasia
okc
Treatment:
Extraction of the involved
teeth and curettage of the
periapical tissue
Root canal therapy can be
carried out
Eneucleation and
marsupialization
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80. Residual cyst is a term of convenience because no teeth
are left by which to identify the lesion
May be found in any of the tooth bearing areas of the
mandible or maxilla
It could develop in a dental granuloma that is left after
extraction
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81. Usually asymptomatic and often discovered on
radiographic examination
May be some expansion of the jaw or pain in the case of
secondary infection
More common in mandible as compared to maxilla
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83. location: Apical regions of
the tooth-bearing portion
of the jaws.
Size: Variable, usually 2-
3 cm in diameter.
Shape: — Round
— Monolocular.
Outline: — Smooth
Well defined
— Usually well
corticated
Radiodensity: radiolucent
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84. Effects on surrounding structures. Residual cysts
can cause tooth displacement or resorption. The
outer cortical plates of the jaws may expand.
The cyst may invaginate the maxillary antrum or
depress the inferior alveolar nerve canal
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87. Also called buccal bifurcation cyst, mandibular infected
buccal cyst, inflammatory collateral cyst, inflammatory
lateral periodontal cyst, Craig’s cyst
First described by Craig in 1976
A cyst of uncertain origin found primarily on the distal
or facial aspect of a vital mandibular third molar
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88. Occurs between the ages of 10 and 39 but
more common in 3rd decade of life
Equal gender distribution
Most of the cyst located distally and
distobuccally to the third molar
Halitosis, acute pain, swelling and trismus
commonly occur
Involved teeth are vital
May occur bilaterally also
Lingual cusp tips may be abnormally
protruding through the mucosa, higher than
the position of buccal cuspswww.indiandentalacademy.com
89. Location : mandibular 1st
molar
Periphery and shape:
well defined corticated
border , circular in shape
Internal structure;
radiolucent
Effects : tipping of the
involved molar so that
root tips are are pushed
into lingual corticated
plate of mandible
,occlusal surface is
tipped toward buccal
aspect of mandible
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93. This cyst develops from epithelial remnants of the
nasopalatine duct or incisive canal.
Clinical features:
Age: Variable, but most frequently detected in middle age
(40-60 year-olds).
Frequency: Most common of all non odontogenic cysts,
affecting about 1 % of total population.
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94. Site: Midline, anterior maxilla
just posterior to
the upper central incisors.
Size: Variable, but usually from
6 mm to
several centimetres in diameter
Shape: — Round or oval
(superimposition ofthe nasal
septum or anterior nasalspine
may cause the cyst to
appearheart-shaped or
resemble aninverted tear drop)
— Monolocular
Outline: — Smooth
—Well defined
—Well corticated (unless
infected).
• Radiodensity: Uniformly
radiolucent but radiopaque
shadows sometimes
superimposed
• Effects: — Adjacent teeth
— distal displacement, rarely
resorption
— Palatal expansion (only
identifiable if extensive
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97. The median palatal cyst
arises from epithelium
entrapped along the line
of fusion of palatal
process of maxilla.
Clinical features:
it is located in the
mid line of hard palate
b/w lateral palatal process
Palatal swelling present
Etiology unknown
Radiographic features:
Location : palatal area
opposite the bicuspid and
molar region
Shape and outline:
A well circumscribed
radiolucent area bordered
by sclerotic layer of bone
Internal structure:
radiolucent
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98. The globulomaxillary cyst is
found with in the bone at
the junction of globular
portion of the medial nasal
process and maxillary
process ,the
globulomaxillary fisssure
usually b/w maxillary lateral
incisor , and cuspid teeth
Clinical features: the cyst
rarely does become infected
and pt may complains of
local discomfort/pain in the
area.
R/F: the cyst appears
inverted ,pear shaped
radiolucent area b/w roots of
the l.incisor and cuspid
causing divergence of roots
of these teeth.
T/T:surgical removal
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100. It is a developmental
condition originating
from proliferation of
epithelial remnants
entrapped in the median
mandibular fissure during
fusion of the bilateral
mandibular fissure during
fusion of bil.mand.arches
Clinical features:
They are clinically
asymptomatic
They seldom produce
obvious expansion of
cortical plates of bone and
assoc.teeth ,react normally
to pulp vitality tests
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101. r/f:
Unilocular well
circumscribed
radiolucency is seen.
t/t:
Surgical excision with
preservation of affected
teeth
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102. Synonynms : naso labial
cysts,klestadts cysts
It arises at the junction of
the globular process ,lateral
nasal process , and the
maxillary process as a result
of entrapped epithelium
along the fusion line
Clinical features:
It cause swelling in the
muco labial fold , floor of
the mouth
superficial erosion of the
outer surface of maxilla may
be produced by pressure of
naso alveolar cyst
r/f: no radiographic features
t/t: surgical excision
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104. Definition:
It is a cystic form of teratoma thought to be derived
from trapped embroyoniccells that are totipotential
Clinical features:
Age:12-25yrs
The swelling which is slow and painless can grow to
several cms in diameter when located in neck or
tongue it may interfere with breathing ,speaking and
eating.
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106. Location:10% head and
neck ,1%oral cavity mostly
in floor of mouth and
tongue ,they may be in
midline /lateral
Periphery and shape:well
defined more radiopaque
soft tissue when compared
to surrounding soft tissue
Internal structures:
conventional radiograph:
radiolucent
Ct scan: soft tissue
multilocular appearance
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108. The aetiology of this cyst is unknown but may be
associated with trauma.
Age: Children or young adults under 20 years.
Frequency: Uncommon.
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109. Site: — Mandible,
particularly the
premolar/molar region.
— Rarely anterior maxilla.
Size: Variable, up to several
centimetres in diameter
•Shape: — Monolocular
— Irregular, but the upper
border arches up between
the roots of the teeth•
Outline: — Smooth and
undulating
— Moderately well defined
— Moderately well or
poorly
corticated.
• Radiodensity:
Uniformly radiolucent.
• Effects: — Adjacent
teeth — minimal or no
displacement, very rarely
resorbed
— Minimal or no
expansion of the jaw.
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111. Differential diagnosis
Kot
Malignant lesion
Treatment:
Conservative opening
into lesion and careful
curettage of lining.
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112. It is a solitary lesion of bone .
Clinical features:
age:20yrs
Site: long bones ,vertebral column, clavicle, ribs , skull
and bones of hands and feet.
The lesions rare painful upon motion , and this soreness
may limit the movement of affected bone
Swelling over area of bone is common
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113. Location : posterior
mandible
Periphery and shape:
well defined, circular
Internalstructure:
multilocular,
In ct images there is
more radiolucent regions
Wispy ill defined septa is
seen
Effects: expansion of
cortical plates
Displacement and
resorption of teeth
Treatment:
Surgical
curretage/excision
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124. Marsupilium = Pouch
First introduced by Partsch in 1892
Definition – “An operation for the cure of a hydatid
or other cyst , the sac of tumour is opened &
emptied of its contents and then its edges are
stiched to the edges of external incision ,which is
kept open while inferior of cyst suppurates & closes
by granulation”
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125. Marsupialization refers to creating a surgical window in
the wall of cyst & evacuation of cystic contents. This
process decreases intracystic pressure & promotes
shrinkage of cyst & bone fill.
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127. Amount of tissue injury – Proximity of cyst to vital structures
could create an oronasal or oroantral fistula, injure
neurovascular structures or vital teeth during enucleation.
Surgical access – If access to all portions of cyst is difficult
,portion of cystic wall may be left behind.
Assistance in erupton of teeth – In a young patient with a
dentigerous or pseudofollicular keratocyst, it permits eruption
of unerupted teeth.
Extent of surgery – Marsupialization is preferred in a
unhealthy or debilited patient , because it is simple & less
stressful for patient.
Size of cyst – in very large cyst,there is a risk of fracture of jaw
during enucleation.
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129. DEFINITION – “The removal of a tumour or other body
entire without rupture,as one shell out the kernel of a
nut”
Introduced by Partsch in 1910.
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130. Enucleation allows for cystic cavity to be covered by a
mucoperisteal flap & the space fills with blood clot,which
will eventually organize & form normal bone.
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132. Treatment of odontogenic keratocysts.
Recurrence of cystic lesions of any cyst type.
Should be employed with any cyst of jaw that can be
safely removed unduly sacrificing adjacent structures.
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133. Dentigerous cyst.
Young patients with erupting teeth.
Medically compromised or debilited patients.
Proximity to vital structures.
Very large cysts,may cause fracture of jaw.
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134. 1) Shear and Speight, Cysts of the Oral and Maxillofacial
Regions, Fourth edition.
2) Shafer, Cysts and Tumors of Odontogenic Origin, A
Textbook of Oral Pathology, Fourth Edition, pg 258-276.
3) Wood and Goaz, Differential Diagnosis of Oral Lesions.
4) Eric Whaites, Essentials of Dental Radiography and
Radiology,, Third Edition.
5) Neville, Odontogenic Cysts and Tumors, Oral and
Maxillofacial pathology, pg
6) Peterson's_Principles_of_Oral_and_Maxillofacial_Surgery_2n
d_Ed_2004
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