Greenway Health provides innovative tools to offer patients greater access to their health information, improving engagement. As a leading health IT company, Greenway partners with over 10,000 organizations and 75,000 providers. Greenway's patient portal and messaging tools allow secure messaging with providers and access to health records, helping patients better manage their care. Under CEO Richard Atkin, Greenway is committed to empowering employees and developing new solutions to help customers succeed in a changing healthcare system.

1. www.insightscare.com
December 2018
PATIENT
ENGAGEMENT
SolutionProviders
2018
The10LEADING
RichardAtkin
CEO
GREENWAY
HEALTH
Offering Providers InnovativeTools that Offer
PatientsGreaterAccess to their
HealthInformation

4. he term ‘Patient Engagement’ is been rapidly emerging and it is today’s buzzword in the healthcare industry.
With its impeccable evolution, it has thrown a long lasting impact on the reviewers, who states that, “No
Tother initiative will have such impact on improving the quality patient care and reducing healthcare costs”.
For years, marketers have been looking for new strategies to engage the customer, create recovering experiences,
and reinforce brand relationships, all of them aimed at improving outcomes. Having called ‘consumer engagement’
in the business terms, patient engagement is the new key strategy that embraces the tools and actions taken by
patients, caregivers as well as healthcare providers. These factors would promote informed decision-making and
behaviors to facilitate improved health consequences.
A recent survey from a renowned organization states that patient engagement is experiencing the biggest development
with the implementation of technology. Today, consumers are considering the online healthcare information
trustworthy. Social media and patient portals, Internet which allow us to fetch what we want at the tip of our fingers,
have also witnessed a significant growth. Being lived in the connected and engaged society; patients as well as
consumers have started expecting the same promptness and easy accessibility from the healthcare industry.
Several latest technologies focused on patient engagement involve managing patient health data, managing
communication with physicians, self-care at home, education, and financial management. Right from wearable tech
and medical devices to patient portals and maintaining personal health records, all of these innovations are aimed at
improving the overall patient experience. With the implementation of health information exchanges, patient portals,
and electronic health records, patients are naturally becoming more involved in their health. Also, healthcare
institutions and practices should embrace and integrate these changes while adapting this new and rapidly evolving
landscape.
Down the line, no one can deny that, patient engagement requires action that must be instigated and sustained by the
individual. It is due to the encouraged providers due to whom patients learn to utilize tools and technology that
produce improved health results. Engagement implies active involvement. All parties must be willing to participate
and embrace the shift to technology to achieve better outcomes and reduce costs.
Perhaps, the healthcare industry is working on par with the rest of the business world and recognizing that to grow
and to compete with the marketplace, patients need more in the way of information, eminence, access, and liability.
Patient Engagement and Technology: A Superlative
Fusion Elevating Healthcare Space
Editor’s Column
Ashwini S. Deshpande,Editor

5. sales@insightscare.com
December 2018
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6. oday, patients are far too occupied to have time to wait around for the services that they don’t need.
Thanks to the digital transformation, with the growth of data and technology, service providers can offer
Tpersonalized healthcare experience to their customers. This metamorphosis, that the industry is
experiencing, marks the future of healthcare. Patient experience is no more confined inside the clinical walls; one
can have access to these from anywhere.
Alongside, having hands on the vast data, the care providers can check the patients’ preferences and customize
the experience for every patient, individually. As the whole concept of patient personalization will not only make
everything easy, but also more effective, the focus on patient engagement is only expected to grow further.
There are a few contributors in the industry aiding to take this concept further and to help the care givers adopting
and applying it. To acknowledge the supreme work of these business giants, we bring to you our special edition of
“The 10 Leading Patient Engagement Solution Providers in 2018”.
In this issue, we have incorporated ‘Greenway Health’ in the Cover Story. Greenway Health is the eminent
organization that provides software services to ambulatory healthcare practices, so that physicians can better run
their businesses and care for their patients.
We have also represented Behavior Imaging®, a company that develops solutions to facilitate the observational,
analytical and collaborative needs of behavioral healthcare and special education professionals; EUPATI which
seamlessly implements a structured program that trains patients and patient advocates on how drug development
works and how all the regulatory processes around it; Medisafe that delivers a state-of-the-art medication
adherence platform to its user; Santovia which has a technology that tackles major issues facing healthcare users
and professionals, by delivering education and targeted surveys it facilitates shared decision making and better
recovery for patients; and UbiCare which is the most prominent patient engagement company which flawlessly
blends its rich experience combining with the targeted, multimedia content with a dynamic platform that allows
complete real-time customization.
Making the issue more exciting, our in-house editors have scripted articles ‘The Role of SharedDecision
Making in Improving Patient Engagement’ and ‘Top Trends that can Boost Patient Engagement to
Optimum Levels’ that will keep you updated with the latest trends going on in the industry.
We have also presented Exclusive View ‘Proteins are Better Biomarkers than Genes’ by Dr. Steven Pelech
who is the Founder, President, and Chief Scientific Officer of Kinexus Bioinformatics Corporation.
So, flip through the pages of this magazine and treat yourself with the innovations in the industry!
The
Personalized
Future of
Healthcare
ENGAGEMENT
Sol
PATIENT
The
10LEADING
SoutionProviders2018
The

8. Providing InnovativeTools thatOffer
Patients GreaterAccess to their Health
Information
EXCLUSIVEVIEW
Proteins are Better
Biomarkers than
Genes
Cover story
CXO Standpoint
34
8

9. UBICARE
EnhancingCare
Quality by
Fostering Patient
Engagement
BEHAVIOR
IMAGING®
Revolutionizing
the Healthcare
Industry One
Child ataTime
16
EUPATI
ARevolutionary
Initiative
Driving Successful
Patient Engagement
throughEducation
18
MEDISAFE
Enhancing
Medical
Adherenceand
Outcomes fora
Healthier
Tomorrow
24 42
32
TRENDS TOWATCH
Top Trends thatcan
Boost Patient
Engagement to
OptimumLevels
Articles
26
SHARED DECISION
MAKING
The Role ofShared
DecisionMaking
inImproving
PatientEngagement
CONTENTS
SANTOVIA
An Integratedand
Comprehensive
Health Engagement
Platform
30
38
EDITOR’SPICK
The Dynamicsof
Social Factors
InfluencingPhysical
Health

10. Providing InnovativeTools thatOffer
Patients GreaterAccess to their Health
Information
Encouraging patient
engagement is a
crucialstep
on the path to
measurable
improvements
in population
health.
“
So
l
The
10PATIENT
LEADING
ENGAGEMENT
SoutionProviders2018
The
COVERSTORY

11. RichardAtkin
CEO
GreenwayHealth

12. n today’s digital world, patients want access to their
health data, test results and providers instantly.
IEmerging tools, such as patient portals and secure
messaging, offerthem greater access to their health
information, which has the potential to encourage
engagement with their physicians more frequently for better
health. One company leading the charge in providing
medical practices with these cutting-edge solutions is
Greenway Health, a leading Florida-based health
information technology and services provider.
Founded in 1977, Greenway has an impressive track record
of serving as a healthcare problem solver, satisfying clients
with its solutions. Over the last several decades, Greenway
has experienced an increase not just in terms of revenue,
but also as it relates to client trust and industry awards and
recognitions. This trailblazing company, considered to be a
market leader in the U.S. healthcare space for more than 40
years, delivers exceptional service through an experienced
team of clinical, financial and technology experts
committed to delivering services that create value for
providers and patients. Greenway’s main goal: to make
patient-driven care a reality while navigating the ever-
changing healthcare system.
To date, Greenway has partnered with more than 10,000
organizations and 75,000 progressive providers across more
“Greenway is
dedicated to
working with
customers to
provide cutting
-edge software
that meets their
unique needs

13. than 40 specialties, which translates into more than 100
million lives that are touched by its solutions.
“An Engaged Patient Is a Happy, Healthy Patient
Today more than ever, providers are experiencing increased
burn out. They are often overwhelmed by hours of
paperwork, revenue concerns, changing government
regulations, leaving them with less time to truly focus on
and care for patients. As such, Greenway partners with
physicians and their teams, providing solutions that make
their lives easier so they can get back to changing patients’
lives. The company has mastered the art in developing
patient engagement tools that offerpatients greater access to
their health information. Greenway’s patient portal, for
example, integrates with Greenway Patient Messaging for
patient-provider engagement. The solution offers easy-to-
use features, such as secure messaging and immediate
views of health records, and also enables users to request,
schedule, and receive appointment reminders.
Greenway’s online patient portal also simplifies
engagement requirements for Meaningful Use and value-
based reimbursements. This is all done through simple, fast
registration, secure messaging, and a view of an
individual’s health record that meets view, download,
transmit (VDT) measure.
When caregivers
receive proper
support, they
deliver better care.
Our robust
solutions assist in
helping practices
achieve success
with value-based
care

14. The success of Greenway’s patient engagement tools can be
best understood from the company’s client advocates:
“Today, patient engagement is huge, and Greenway’s
Patient Portal and Messaging helps us do that better. I
really like how Greenway Patient Messaging gets the right
information to the right patient, in the right manner, and
saves stafftime in the process.” - Bethany Suggs, Systems
Coordinator, Family Medical Associates of Raleigh
“Not being at every appointment with my mother has
caused me worries. With the patient portal - when I can’t be
there - I still can help her manage her health and that’s
important to both of us.” – Nancy Brown, Practice
Administrator, The Veranda
In addition to its patient engagement tools, Greenway offers
electronic heath record and practice management solutions.
A Greenway EHR solution can be exclusively tailored to
the needs of each provider’s practice and their specialty,
allowing for user-focused simplicity to the front office,
clinic and back office.
Leading from Example: Empowering Employees with a
Healthy Workplace
An ace leader is one who fosters an environment of growth,
which ultimately results in greater success of a team and an
organization overall. A leader also provides knowledge and
motivation to its team members, encouraging them to strive
for their best in serving clients, fellow team members, and
stakeholders of an organization. One such strong leader is
Richard Atkin, the CEO of Greenway. Atkin joined the
company in June 2018, bringing extensive executive
experience and a focus on process-driven management, as
well as a deep background in developing talent, team
building and organizational alignment.
Richard joined Vista Equity Partners in 2014 and has
worked with Vista portfolio companies DealerSocket,
EagleView, Finastra, Omnitracs, Solera, and STATS. Prior
to his role as an operating principal, Richard was the
President of Vista Consulting Group from 2014 to 2017,
where he helped the organization evolve and scale to
support the growth in the Vista portfolio. Before joining
Vista, Richard handled the prestigious posts of president
and chief executive officer of Sunquest from 2005 to 2014.
Richard believes employees are the real assets of any
organization. As such, he promotes a healthy and conducive
work environment, and emphasizes a special focus on the
personal growth and professional development of each
individual. His goal is to provide his team with knowledge
and motivation, encouraging them to strive for their best
each and every day. Greenway does this by offering
ongoing training, educational sessions and additional
learning activities to foster collaboration among its team
members. This enables colleagues to continue to grow
throughout their career and ensures that award-winning
customer support can be achieved each day.
At Greenway, Atkin is known for his sheer dedication and
diligence to better serving customers, working endlessly to
help them achieve success. He considers his team to be
problem solvers, working each day to truly understand the
challenges Greenway customers face, from ever-changing
government regulations, deadlines, and security and
compliance requirements, to also maintaining profitability.
He encourages his team to take charge of all situations,
making decisions that are in the best interest of those who
matter most – Greenway customers.
Looking Ahead to a ProsperousFuture
Greenway is committed to bringing continuous innovation
into its products and is very optimistic about its future
success. The company is currently developing a next-
generation platform that will help customers succeed amid
the constant industry change, in particular the movement
toward value-based care. The company’s state-of-the-art
next-gen platform will focus on workflows, documentation
and device integration. It will reimagine a healthcare
practice’s daily tasks from start to finish with a goal of
seamless performance.
“AtGreenway Health, we put
possibility intopractice”

17. Company Name Management Brief
Behavior Imaging®
behaviorimaging.com
Ron Oberleitner
CEO
The company develops solutions to facilitate the
observational, analytical and collaborative needs of
behavioral healthcare and special education professionals.
eHomeCare
ehomecare.com.au
Hubert VanDalen
CEO
eHomeCare connects smart care technologies solutions to
complement other aged and healthcare services.
EUPATI
eupati.eu
Matthew May
Program Coordinator
It is a pan-European program implemented as a public-
private partnership by a collaborative multi-stakeholder
consortium from the pharmaceutical industry, academia,
not-for-profit, and patient organizations.
GetWellNetwork
getwellnetwork.com
Michael O’neil
CEO
GetWellNetwork acquires HealthLoop to provide the very
best in digital patient engagement solutions for providers,
patients and their families.
Greenway Health
greenwayhealth.com
RichardAtkin
CEO
Greenway Health provides software services to ambulatory
healthcare practices, so that physicians can better run their
businesses and care for their patients.
Medisafe
medisafeapp.com
Omri Shor
CEO & Co-founder
Rotem Shor
CTO & Co-founder
Medisafe provides a state-of-the-art medication adherence
platform to its users.
MedSymphony
medsymphony.com
Jamie Simmons
Founder
MedSymphony was created to empower physicians, health
institutions as well as patients with a complete mobile health
technology platform.
Santovia
santovia.com
FionaCalnan
CEO
Santovia’s technology tackles major issues facing healthcare
users and professionals, by delivering education and targeted
surveys it facilitates shared decision making and better
recovery for patients.
SynsorMed
synsormed.com
Theo Harvey
CEO
Synsormed is transforming patient engagement with the
telehealth and patient monitoring platform.
UbiCare
ubicare.com
BetsyWeaver
CEO
UbiCare empowers hospitals to create efficiencies and
reduce costs by engaging patients earlier in the care
episode.
ENGAGEMENT
Solu
The
10PATIENT
LEADING
SotionProviders2018
The

18. ccording to the Stanford Medicine News Center,
demand for autism treatment is over eighteen times
U.S. Combine that demand with a climbing prevalence in
autism diagnosis – the CDC (Centers for Disease Control
and Prevention) reported a growth of over 15 percent this
year – and many individuals and families are left waiting
for answers. Individuals with autism and their families
require timely diagnosis and treatment but are often stopped
by the barriers of distance, cost, and unavailability of
experienced providers.
Boise, Idaho based, Behavior Imaging®
is one prominent
organization that works to eradicate all these barriers. They
relentlessly focus on developing technology that increases
disabled people’s access to care. The company has served
over 20,000 clients in ten countries to date and has major
clients such as the US Air Force, State Departments of
Education, and several leading universities.
The company has also won awards from the Small Business
Administration (awarded in 2016 at the White House) and
the Google/Autism Speaks award for its disruptive business
model that allows families to share clinically relevant data
from their homes to accelerate their child's diagnostic
assessment.
Story behind BI’s Inception
Ron and Sharon Oberleitner founded Behavior Imaging®
in
2005. Since their son’s autism diagnosis in 1996 at the age
of three, the challenges of receiving specialized care for
those with intellectual disabilities hits close to home for the
Oberleitners. To date, Ron and Sharon have dedicated their
careers to assisting families and organizations, improving
their accessibility to behavior health treatment through a
unique asynchronous telemedicine platform – Behavior
Imaging®
.
Behavior Imaging®
Revolutionizing theHealthcare
Industry One Child ataTime
Alarger than the available supply of caregivers in the
Ron Oberleitner
CEO
16 | December 2018

19. “Shine aLight
onAutism
and Beyond
About the Perceptive Leader
The CEO, Ron Oberleitner holds more than two decades
of enriching executive management experience within the
health industry including medical devices, telemedicine,
and medical imaging solutions. His personal experience
with autism and professional experience from the medical
device, nonprofit, and research industries fuels a passion to
help others by creating and expanding solutions for better
diagnostic, assessment, and continuity of care for a variety
of behavioral and mental health challenges. Besides, he
brings an attitude of ‘why NOT our kids’ when it comes to
using innovative technology to address difficult health
conditions.
Ron believes that an ideal leader in the health IT industry
(be it telemedicine, digital therapeutics, or digital
assessments) recognizes the current barriers and resist to
change for disruptive patient engagement solutions. “This
ideal leader works hard and tirelessly to overcome
objections and demonstrate profound benefits through
responsible research and compassion for both struggling
patients and the well-meaning clinicians who serve them”,
says Ron.
Unrivaled Services of BI
Behavior Imaging® works to take behavioral care beyond
in-person assessment and treatment into a fully realized
technological landscape. By using smart phones, video
capture, and artificial intelligence, behavioral care becomes
more efficient and cost effective for the people who need it
most. BI products provide patients and their
doctors/clinicians with the solutions for understanding
autism and behavior health needs. The benefits are similar
to the ways X-rays and MRI’s have allowed patients to
show medical doctors broken bones and tumors.
NODA™ is Behavior Imaging’s evidence-based Autism
diagnostic service platform that addresses many challenges
hindering an earlier diagnosis. Behavior Imaging has led
several National Institute of Health-funded research studies.
The most recent study compared current in-person autism
assessment practices with the NODA smartphone-based
method. The research showed that the NODA method cut
the average total time for an autism spectrum disorder
(ASD) assessment in half – saving on average two months
for families.
Fostering Employees with Active WorkEnvironment
It is well said that, “Practice is the hardest part of learning,
and training is the essence of transformation.” BI precisely
follows this concept, which can be observed from its
distinctive approach. BI employees regularly receive
outside training in areas relevant to their position, paid for
by BI. They also have direct hands-on experience with
colleagues with disabilities who perform special tasks for
the company. BI emanates a culture of ‘family first,
Behavior Imaging second’– which helps to attract and
retain the right employees.
Foreseeing a Bright Future
Besides providing a well-equipped and advanced work
surrounding to their employees, BI leaves no stone
unturned to stay abreast of the industry requirements.
According to BI, an ace patient engagement solution
provider should leave patients and their families/caregivers
feeling empowered to take an active role in care. BI also
believes that, when families are concerned about their loved
one’s health, patient engagement solutions should enable
clinicians to fetch helpful information about their patients.
Today, the healthcare market is waking up to the benefits of
capturing health data as it’s happening and sharing it with
knowledgeable doctors remotely to get earlier diagnosis and
guidance on treatment. In the next few years, Behavior
Imaging plans to integrate artificial intelligence to help
clinical professionals make quicker and better-informed
decisions as they assess behaviors and recommend
treatments.
ENGAGEMENT
So
l
Th
e
10PATIENT
LEADING
SoutionProviders2018
The
December 2018 17

20. With its long expertise in the healthcare field and
recognition as an objective education provider,
EUPATI (The European Patients Academy on
Therapeutic Innovation) is a valuable resource for anyone
looking to do Patient Engagement. It can be done through
its publicly available tools or by collaborating to find a
solution to the clients’ specific needs.
The patient community has dreamt to empower patients to
be an active partner in medicines research and development
(R&D) for some time. In some disease areas, the patient
community has been involved in R&D for a decade or two,
which needed an advanced and systematic approach.
EUPATI seamlessly implements a structured program that
trains patients and patient advocates on how drug
development works and how all the regulatory processes
around it. It also educates the stakeholders to engage
patients on how to do so in an effective and systematic way.
Illustrious Course
The EUPATI Expert Training Course is an exciting and
unique opportunity offering patients and patient advocatesthe
expert-level training in medicines research and
development. It is a mixture of independent e-learning
coursework and face-to-face training events spread over a
14-month period.
EUPATI provides support through the toolbox and guidance
documents for all stakeholders to enable effective
engagement of patients. It will be releasing training for
industry in 2019 and for other stakeholders in the future.
The academy believes that for effective patient engagement,it is
necessary to ensure that all involved stakeholders have the
capacity to implement systematic patient engagement.
EUPATI was established in the first instance to increase
capacity within the patient community by developing
training and information material dedicated to increasing
the knowledge of patient advocates so they can operate at
an expert level. This gave rise towards the contribution to
the establishment of frameworks under which patients can
successfully and ethically work with other stakeholders to
EUPATI
A Revolutionary Initiative Driving SuccessfulPatient
Engagement throughEducation
Matthew May
ProgramCoordinator
December 201818

21. “Wefocus on education and
training to increasethe
capacity and capabilityof
patientsto
understand and contributeto
medicinesresearch
anddevelopment
ensure the optimum development of medicines and access
to healthcare.
Words of Gratified Clients
EUPATI’s strength lies in its construction as a public-
private partnership and as a collaborative multi-stakeholder
consortium of patient organizations, the pharmaceutical
industry, academia, and not-for-profit organizations hosted
at the European Patients' Forum. EUPATI’s products are not
only designed by multi-stakeholder teams but also delivered
by them. This ensures that the company can offer the first-
hand experience of patient engagement for both the ‘sides’
of engagement. Being a customer-centric company,
EUPATI has made many clients satisfied with its services
and solutions and below are few of them.
 “EUPATI has been a game-changer in the
empowerment of patients because we can see people
trained by EUPATI almost everywhere, be it in
regulatory committees, industry-led research projects
and clinical trials, academic projects or ethics
committees.”-Jan Geissler, Patvocates & LeukaNET.
 “The expert training course is certainly a unique asset
and achievement with almost 150 patient experts
trained and more on the way. They are the ones who
can really actively participate in all the decision points
with the industry, regulators and HTAs [health
technology assessment bodies]. Beyond that, I think
the toolbox on medicines R&D, the material that is
available on the website and now used by more than
1.2 million people worldwide, is a huge achievement
and allows everyone around the world to use the high
quality-controlled material.”- Matthias Gottwald,
Bayer Pharma
Elevating Employee’s Growth by Rendering Diverse
Opportunities
EUPATI provides a unique opportunity to the individuals
involved on behalf of their organizations in the public-
private partnership to form relationships with other experts
across their own and other stakeholder groups. This melting
pot of personalities, perspectives, and expertise not only
gives EUPATI its strength, expertise, and authority but also
empowers and develops its members to drive effective co-
creation and engagement within their own organizations.
This would also encourage its employees with a strong
network that provides endless continuous professional
development.
The professionals at EUPATI work together to bring its
pieces of the medicines R&D puzzle together to ensure
that EUPATI trained patients have the necessary broad-
spectrum knowledge to represent their communities.
EUPATI strongly believes that- “The essence of Patient
Engagement is about co-creation and partnership.
Therefore, Patient Engagement Solution Providers need to
walk-the-walk themselves, designing their solutions as a
partnership between patient experts and others. This
ensures that the solutions put in place meet both the needs
of the companies and the communities with which they are
engaged, ensuring expectations are met for all, and
effective medicines development occurs to bring made-for-
purpose medicinal products to market in a safe, efficient,
and cost-effective way”.
Upcoming Plans
Today, patient engagement is being recognized across the
industry as being a necessary component of modern
medicines development. EUPATI initially developed the
capacity in the patient community in Europe to build the
community of patient advocates that are able to engage at
an expert level. With this approach, pharmaceutical
companies and patient organizations are recognizing their
lack of infrastructure and capacity to implement systematic
patient engagement throughout the life-cycle of medicines
R&D.
EUPATI has set a framework for patient engagement with
four stakeholders i.e. pharmaceutical industry, ethics
committees, regulatory authorities, and health technology
assessment bodies in 2016. Since publishing them in
Frontiers in Medicine in 2018, EUPATI will be rolling out
training programs aimed at these stakeholders ensuring that
the things will be executed flawlessly.
ENGAGEMENT
So
l
Th
e
10PATIENT
LEADING
SoutionProviders2018
The
December 2018 19

22. HIVSTILL ANIMPENDING THREAT TO
IV research has come a long way since the disease was discovered in the 1980's.
Antiretroviraltherapywas a majormilestonethathas changed the livesof millions,
Hbut the goal now is to find an HIV cure before 2020. Over the past several decades,
researchershavelearnedalotaboutthehumanimmunodeficiencyvirus(HIV)andthedisease
itcauses,acquiredimmunodeficiencysyndrome(AIDS).
MANKIND
December 201820

23. Stopping the
replication of HIV
Last year in a clinical trial
scientists showed that this
approach has the potential to
become a functional cure forHIV.
The key to its potential is that it
can target the reservoir of HIV
viruses that “hide” inactive
within our cells. Current
therapies suppress the virus in
circulation by inhibiting the
formation of new viruses, but
they don't touchthe reservoir.
Once you stop, the virus comes
back in 10-14 days.ABX464 is the
first drug candidate ever shown
to reduce the HIV reservoir.The
drug, called ABX464, binds to a
specific sequence in the RNA of
the virus, inhibiting its
replication.
Shock and kill
Another approach that is
becoming popular in the fight
against HIV also goes aGer the
hidden HIV reservoir. The “shock
and kill” or “kickand kill”
approach uses latency-reversing
agents (LRAs) that activate or
“kick”the latent HIV reservoir,
making it possible for standard
antiretroviral therapy to “kill”
these viruses. In 2016, a group of
UK universities reported
promising results from one
patient treated with this
approach. A similar strategy
using vaccine is currently being
tested. One stimulates the
production of antibodies that
block the replication of HIV,while
the other attacks thereservoir.
December 2018 21

24. Immunotherapy
What makes HIV so dangerous is
that it attacks the immune
system, leaving people
unprotected againstinfections.
But what if we couldsupercharge
immune cells to fightback?
That's the reasoning behind
immunotherapies. Researchers
reported last year that thanks to
an immunotherapy that primes
the immune system against the
virus, 7 out of 15 patients were
cured. Their approach combines
a drug to activate the hidden HIV
reservoir with a vaccine that can
induce an immune response
thousands of times strongerthan
usual.
Gene therapy
It is estimated that about 1% of
the people in the world are
naturally immune to HIV.The
reason is a genetic mutationon
the gene that encodesCCR5, a
protein on the surface of
immune cells that the HIVvirus
uses to enter andinfect them.
People with this mutationare
missing part of the CCR5 protein,
making it impossible for HIV to
bind to it.Using gene therapy, it
would, in theory, be possible to
edit our DNA and introduce this
mutation to stop HIV.In the
future, gene therapy for HIV
could be done with CRISPR, a
gene editing tool that is much
easier and faster to make. Its
potential in HIV has already been
shown in vitro, and soon HIV
could become of the first
diseases to be cured with CRISPR.
WhenwillwehaveanHIVcure?
Although there are several approaches that could eventually bring a functional HIV cure, there are still some
challenges ahead. One of the biggest concerns around any HIV treatments is the virus' ability to quickly mutate and
develop resistance, and for many of these new approaches there is still no data on whether the virus will be able to
become resistant. So far, none of these functional cures have reached late-stage clinical testing, meaning it doesn’t
seemlikelythatwe willmeetthegoalofhavinganHIVcureby2020.
| December 201822

26. wo brothers, Omri and Rotem, were sitting in the
lobby of a hospital, in front of the emergency room.
TThey were waiting for their father, a diabetic
patient who, while taking his every day dose, had
accidentally injected a second dose of insulin, to get better.
Fortunately, he was fine. But, both the brothers, after
spending the day in that lobby, wondered how it was
possible that there was no tool to help people manage their
medications and prevent mistakes like not remembering to
take their meds or double dosing. After researching over
this, they realized that no such solution was available and
therefore, set out to create one. That is when Medisafewas
born. Medisafe is the brain-child of the brothers- Omri
Shor, the CEO and Co-founder, and Rotem Shor, the
CTO and Co-founder of the company.
Medisafe is a fast-moving patient engagement business that
has created easy-to-use, personalized technology to help
people manage their health better. It provides a state-of-the-
art medication adherence platform to its users. Talking
about the company, Omri says, “Medisafe helps people
manage their medications easily and effectively. We provide
our pharma partners with insights into patient behavior
and ways to engage with their patients.”
Medisafe is headquartered in Boston, Massachusetts, with
its major operation center in Haifa, Israel. When incepted in
2012, the founders’ dad was Medisafe’s app’s first user, and
today, it has over 4.5 million users in 150 countries.
Commitment to Saving Lives
Realizing that almost 125,000 people die each year in the
U.S. as a result of not taking their prescribed medications
MedisafeEnhancing Medical Adherence and
Outcomes for aHealthierTomorrow
Omri Shor
CEO &Co-founder
24 | December 2018

27. “We save
livesby
making
medication
management
easy
properly, Medisafe is committed to changing this scenario
for better. With its medication adherence app, Medisafe has
been improving adherence significantly.
Another severe problem that Medisafe addresses is that of
dangerous drug interactions (DDI). Recent estimates
indicate that DDIs cause nearly 74,000 emergency room
visits and 195,000 hospitalizations each year in the USA
alone. Since its introduction a year ago, Medisafe's drug
interaction feature has warned patients of more than
100,000 potentially dangerous drug interactions.
A ‘Client-First’ Company
Always a client-first company, Medisafe has ensured to
offer patients and its customers the best. A testimony to thisis
the app’s 4.6 rating, out of 5, on the app stores. Many
reviewers have talked about their stories - of how Medisafe
has saved their lives, or how it has dramatically improved
their quality of life by making medication management
much simpler.
On the business side, the company offers its pharma
partners a way to gain a much better understanding of the
behavior of their patients, and a way to engage with them
and improve adherence. Addressing the benefits this
provides, a prominent client of Medisafe- Leif Moll, Head
of General Medicine Strategy & Portfolio Expansion, at the
biopharma business of Merck KGaA, Darmstadt, Germany,
said: “With Medisafe, we would like to help patients with
chronic conditions to better organize their medication,
therefore improve adherence to their regimen and ultimately
achieve the best possible treatment outcomes.”
Outshining its Peers
Medisafe’s success puts it on a different level from
competing medication management platform solutions, as
with 4.5 million registered users it is by far the leading
platform. The ease of use and intuitive interface, the fact
that the company has addressed all therapeutic areas,
unique features like Medfriend, and the drug interaction
checker – all make Medisafe uniquely effective. Its large
and highly engaged user base makes it particularly
attractive to pharma partners, as the company can provide
insights into much larger groups of patients.
Life at Medisafe
At Medisafe, ownership is a central value. Everyone who
works at Medisafe has to take ownership of projects and
overcome new challenges, every day. The biggest
opportunity that working at Medisafe provides is to
improve people’s quality of life, and even save lives. The
company gets amazing feedback every day with people
sharing incredible stories, and it has made it a habit that the
entire team sees these as a major motivation for everyone.
Medisafe also provides individual support for employee
development. “Ideal leadership is inspiring and visionary,
driving the team to greater successes, while giving them the
freedom to pursue their creativity and initiatives,” asserts
the CEO.
Future Endeavors
Over a third of older adults in the U.S. regularly use 5 or
more medications or supplements. Over 100 million people
who, if they used a medication reminder and drug
interaction checker – would be healthier and safer, and the
global number is many times higher. Driven by the same
goal, Medisafe wants to reach not 4.5 million users, but 450
million users, and it is confident that this is achievable. Shor
asserts, “We strive for a future in which people no longer
die or are hospitalized because of medication mistakes, and
we believe Medisafe can help make it happen.”
ENGAGEMENT
So
l
Th
e
10PATIENT
LEADING
SoutionProviders2018
The
December 2018 25

28. Healthcare professionals are constantly under
consumer’s pressure and their requirements.
Physicians, regulators, and health providers are
figuring out the best way required to engage the patients in
their own medical care. Hence, organizations have shifted
to shared decision making (SDM) as a key strategy in
bringing out the role of patients in their own treatments.
SDM enables physicians and patients to share the decisions
to arrive at a mutual agreement in the care plan, tests, and
the treatment. Physicians base these results on the clinical
evidence, balance of risks, and expected outcomes along
with the patient’s values and preferences.
By implementing mutual decision via patient education and
communication, patients can progress beyond participation
and can develop into health collaborator. From the
provider's view, SDM obliges them to merge their clinical
expertise realizing that the patients can understand their
difficulties alongside acknowledging their value and
priorities. Hence, the call for the SDM is emerging now and
is seeking more value-based and patient-centred healthcare.
Time limitation and the knowledge accompanying with the
regulatory action has demeaned the SDM and has allowed it
to flow under the radar of the healthcare providers.
Consequently, the healthcare professionals require
education on SDM and how to practice it to set up a
collaborative environment for the patients and the clinical
staff.
Usage
Experts break SDM down in simple and stable steps. They
represent it as a simple example like identifying the patient
condition, reviewing the treatment options, testing the
patient’s preference and values, and carrying out the
decision.
The emerging challenges in these basic steps lie in the
present workflow and on the provider’s part via irregular
communication with the patients. Such false and inferior
Therole
OFSHARED
DecisionMaking
INIMPROVING
PatientEngagement
| December 201826

29. Shared DecisionMaking
information will erode the purpose of the applied decision.
In addition, the absence of clarity while considering the
treatment choices can leave the patient with the inadequate
information in carrying out a healthy decision or can further
confuse them, overwhelming them with information.
The Agency for Healthcare Research and Quality suggest
the user of acronym SHARE while discussing the SDM.
-Seeking patient’s participation
-Helping patient in exploring the treatment options
-Accessing patient’s value and preference
-Reaching decision with the patient
-Evaluating the patient’s decision
Challenges
SDM is a perfect strategy for engaging the patients;
however, it faces numerous challenges. First one is related
to the awareness of the SDM. There are only a few
caretakers that actually know about the SDM practice or the
best way of facilitating it. Healthcare providers already
struggle as they cope with the regulatory burdens, quality,
reporting programs, schedules, and other healthcare sector
demands. Integrating the SDM in an already congested
schedule can lengthen the framework and can impede their
workflow. However, critics believe that SDM does not take
away much clinical time. Studies have accompanied these
decisions by showing positive to mix results.
Physicians can practice SDM to their likeness and enjoy the
outcomes as they help patients to improve quality and their
understanding. Providers just need the strategies that can
promote SDM in accommodating a place in their clinical
practice. Leaning on care coordination, team-based models,
and nurse communications can help physicians in
establishing SDM into practices.
Overcoming these restrictions with the knowledge, time,
and consistency may prompt many other industries in
creating resources required to implement the SDM.
December 2018 27

30. Benefits
As medical decisions are always complicated, therefore, it is essential for general citizens to welcome information from
healthcare providers, caregivers, or even from patients. The primary goal of SDM is to enlighten patient and provide them
with access of the evidence-based decisions that further aid the patients in learning them about their care options and make
decisions that align with their preferences and care goals. Hence, the tools like interactive media and multimedia are meant to
be the partners of the conversation, taking place between the patient and healthcare provider. This can help in guiding the
patients in forming strong decision even when they are stuck in complicated situations.
Experts believe the despite hurdles and obstructions, SDM can have a positive impact on the clinical elements. A study
published in 2012 illustrated that SDM helps patients in revealing anxiety about the health care costs, which further allows
the patients in choosing the best and personal care priorities and treatment budgets. A separate study reveals that SDM
reduces the preventable hospital readmissions, which aid the patients in deciding the best treatment that is beneficial for
them.
SDM also supports informing the value-based care models. Using these models, patients can opt-out of the expensive and
potentially ineffective treatment options and can choose an option that works for their imminent needs. This is more likely to
yield long-lasting results in the long-term. For example, in the last stage of cancer, a patient can pursue less aggressive
treatment based on the comfort at the end of their life. It is important for them to live the last moments of their life as
comfortable as possible. Ultimately, SDM can be counted as the key that ensures that the patients see results that they truly
want.
Physicians are experts on the diseases; hence, they are the best person who can provide insights into the treatment. They can
enlighten patients with the side effects or other various aspects of the treatment that can influence patient’s lives. SDM
ensures that healthcare providers accommodate the patient preference in the care. In the end, it depends on the patient what
he/she prefers, their needs, values, and their incorporation of the treatment planning. Allowing patient’s participation intheir
own care can be the key for a better outcome and higher patient satisfaction. Physicians that implements and practice SDM
must share their models so they can offer the benefits linked to the practice. Consequently, this will make it easier and more
workable for other hospitals and clinics to foster SDM into their healthcare.
| December 201828

32. antovia provides targeted patient education, and
resources that promote shared decision-making, and
Sbetter outcomes. Santovia is happy to announce its
new partnership with EBSCO Health and the new
integrated Option Grid solution for providers. The Option
Grids are build on years of evidence-based research to
guide people through life’s major health decisions
Its surveys are used by healthcare providers to improve
patient satisfaction through rapid feedback. Santovia also
supports patient reported outcomes by measuring recovery
and keeping track of how patients are progressing.
The need for better patient engagement has never been
higher, and with more people than ever using technology,
the fundamentals are falling into place for Santovia.
“It’s often those who least have access to technology that
need the information most.” This insight is an important
driver in the development of Santovia. Headquartered in
Boston MA, Santovia was launched in 2016. Santovia is
optimized for all platforms: mobile, tablets, desktops and
even paper for those that want it.
The inspiration behind Santovia was its recognition that
patients need better education and everyone in the system
needs to communicate more effectively. For Santovia, this
means high-quality educational materials tailored
specifically for each individual patient. It aims to consign
poor-quality photocopies with obscure diagrams and
difficult jargon to the trash heap. Instead, Santovia provides:
• Extensive easy-to-understand content that explains what
patients need to know about their conditions and
procedures, in video and written format, and in both
English and Spanish;
• Conversational videos with expert doctors explaining
exactly what behavior patients need to change;
• Physical therapy exercises videos;
• A wide library of customizable surveys to support rapid
Santovia
An Integrated andComprehensive
Health EngagementPlatform
Fiona Calnan
CEO
30 | December 2018

33. “Santovia is theonly
integrated solutionthat
allowsproviders
to deliver qualityvideo and
written education almaterials,
offering the addedadvantage
for providers to assign theirown
customizedcontent
topatients
and accurate feedback about patient care and how
conditions are progressing.
Words of Happy Clientele
“Evidence shows that informed patients make more cost-
effective decisions.” says Fiona. The company works with
providers, employers, and insurers to reduce healthcare
costs and increase profitability.
Dr. Donald Rice, M.D, stated that when the clinic switched
from their old vendor to Santovia, the staff noticed
immediate improvements. “We had searched for a new
provider for many years, so it was nice to see a proactive
company like Santovia step up and address all of our
concerns.” Feedback from both staff and patients has been
very positive reaffirming they made the correct choice in
partnering with Santovia. According to Dr. Rice, “Theuser
interface window was incredibly well designed. The
Santovia portal seamlessly ties into the Urgent Care
Clinic’s medical record system making it easy to remain
paperless. It pulls the proper handout and documents the
delivery to the patient. We had used third party educational
providers and by far, Santovia is far superior. They clearly
‘get us’ and ourneeds.”
Astute Leadership
Before moving to the U.S., Santovia’s CEO, Fiona Calnan
successfully created a built a network of hospitals in the UK
that delivered the best patient outcomes for orthopedic
procedures in the country. Great clinical care was clearly an
important part of this achievement but helping patients to
fully understand what they need to do to recover effectively
was just as important an ingredient. Fiona’s pioneering use
of technology to help patients understand how to boost their
recovery was recognized by industry awards.
It’s those insights, both about the need for patients to be
fully engaged in their recovery and how to harness
technology to support learning, which inspired Calnan to
move to the US to bring those pioneering achievements to a
wider audience by working with Santovia’s founder, Dr
Ibrahim Eid.
The Uniqueness of Santovia
Santovia’s patient education platform provides an
unrivalled breadth and depth in both written and video
content. Santovia integrates surveys that give deep insights
into each patient’s experience of care and how their
treatment is progressing. Santovia is assessible directly
from the providers’ EMRs and content can be viewed
through patient portals, health apps and printed at the point
of care.
Santovia is the only solution that brings all these
approaches together in one package. The Santovis platform
aligns all healthcare participants towards a common goal: to
achieve the highest quality care in an efficient and cost-
contained environment.“Everybody wins. Patients, and
providers all benefit from Santovia. We listen and act on
their feedback.” asserts Fiona.
Speaking about the working close with customers, Fiona
says, “The team are all close to customers, spending
significant amount of time understanding their needs and
then translating that directly into new features and product
enhancements.”
Future of Santovia
Santovia has already established itself as the most
comprehensive patient engagement platform in the market,
“but this is just the tip of the iceberg” they say. Immediate
plans include rollout expansion of its teleconsult capability
to enable patients to access expert physicians on demand.
Other areas in development include expansion of its
cutting-edge physical therapy videos to cover even more
exercises to improve recovery at home.
It has already helped thousands of patients make better
decisions and aims to reach many more people by helping
employers create a healthier culture and support their
employees' health care choices.
ENGAGEMENT
So
l
Th
e
10PATIENT
LEADING
SoutionProviders2018
The
December 2018 31

34. Patient engagement is a continuous process. It does
not end within the four walls of a clinic or hospital.
Nowadays, with more awareness and desire to live
healthy lives, it is vital for healthcare providers to provide
an uninterrupted and better support along with guidance to
make patients healthcare journey a happier one which will
be based exclusively on trust and empathetic care. Here we
bring some exciting facets of healthcare that are becoming
popular for better patient engagement.
Health 5.0
Health 5.0 has become the latest buzzword in the field of
healthcare. This more recent version of healthcare is more
focused towards personalization and emergence of digital
wellness. What’s new in this new stage is patients are
recognized as customers and from a patient-centric
healthcare, 5.0 is tilting towards customers centric wellness
services.
The main focus in this face of healthcare is more towards
prevention than cure.
Health 5.0 utilize AI analysis of big data spanning over
diverse types of information, including personal real-time
physiological data, environmental information, healthcare-
site information, treatment/infection information to help
customers in:
• Promoting healthy living and early detection of diseases
through real-time automatic health checkups
• Providing ideal treatment anywhere through the
sharing of physiological and medical data
• Using robots to ease the on-site burden of healthcare
and caregiving
Moreover, these solutions will assist reduce the social costs
associated with healthcare and caregiving and solve labor-
shortage problems at healthcare sites.
Health Education
No one wants to be in the dark when it comes to any kind of
dental treatment. Everyone wants to know about the
detailed procedures and techniques the doctor perform
while treating dental patients. As the awareness level on the
rise, more and more patients want to know about their
treatment procedures in advance. Educating the patients
about the treatment can significantly improve the patient
experience. Increasing patient engagement not only does
help in augmenting patient’s knowledge and skills but also
builds their confidence in managing their health.
Top Tr e n d s t h a t
c a n B o o s t
P a t i e n t
E n g a g e m e n t to
O p t i m u m
L e v e l s
| December 201832

35. Educating the patients can bridge the gap between patient
and healthcare providers and assist:
• Patients in taking accountability for their health
• Patients in practicing prevention techniques at home
• In developing patient trust, satisfaction, and loyalty
• In increasing treatment acceptance rate
• In safeguarding the continuity of care between
appointments
• In empowering the patients to decide the best plan of
action
Moreover, rural or population with low health literacy,
educating about the treatments and other can prove to a
boon for the healthcare sector. As many within these
populations have not experienced healthcare delivery that
emphasize or encourage high levels of patient engagement.
The Arrival of Tech Gadgets
Wearable gadgets are becoming popular in today’s fast
paced-life due to its fascinating features and compelling end
results on the go. Whether you want to track your sleep,
movements, heart rate, physical activities, calories burnt,
distance traveled, active time, activity break-up in a day, or
more, wearable gadgets does the work for you in a
proactive manner. The ability to produce vital body stats in
a hassle-free manner is what has been attracting consumers
towards wearable gadgets. In a prominent survey, it was
found that use of technology gadgets have increased
multifold between 2014 and 2016. What’s more interesting
is whopping 76 percent of patients’ follow physicians’
recommendation to use wearable gadgets as they feel more
empowered with its usage and effectiveness.
Moreover, the integration of wearable gadgets and
electronic health records has expanded the patient’s
satisfaction level towards the optimum. The doctors have
become more empowered to get the deeper insights about a
particular patient’s daily activities, which ultimately assist
physicians to advice better guidance to the patients. All
these make the patient’s journey fruitful and assist them to
live a healthy life.
Although the list is endless, and there are many other trends
which are gaining popularity, but one thing that is common
is – Patients are now- no more just concerned about the
recovery from their diseases; they want to know about its
prevention as well. Doctors and healthcare providers thus
need to gear up to match the growing expectation from a
tech-savvy and highly educated world population in order
to maintain a cordial relationship and better patient
engagement for a sure success.
December 2018 33
Trends toWatch

36. Dr. Steven Pelech
Founder, President, &
Chief Scienti c Of cer
| December 201834

37. PROTEINS ARE BETTER
BIOMARKERS THAN GENES
he costs of sequencing the order of nucleotide bases
in the DNA strands found in chromosomes have
Tplummeted by a million-fold over the last 25 years.
The entire sequence of 2.9 billion nucleotide base-pairs in a
single human genome can now be determined for less than
$1000. Complete genomes of hundreds of thousands of
people are expected to be sequenced over the next decade.
While the acquisition of such genomic knowledge was
originally forecasted to herald better diagnostics and
therapeutic treatments, the actual deliverables for improved
health care have been disappointing. Excluding cancer, it
has become apparent that only about 10% of the cases of
the most common diseases that afflict our population have a
genetic basis that can be ascribed to hereditary mutations in
the DNA sequences of specific genes.
Over 100 million single nucleotide variants appear to exist
in the human population, and perfectly healthy people
appear to commonly harbour about 100 or so serious
disease-associated mutations without any apparent
manifestations of these particular diseases. Studies, with
over 50,000 genetically identical twins, have shown no
increased risks for the 24 most common diseases amongst
the twins than for a twin with the general population.
Over 95% of the known 21,300 genes carried in the human
genome serve as the blue-prints for the construction of all
of the cellular proteins, known as the proteome. These
proteins function like molecular robots to regulate and carry
out all of the biochemical reactions needed to keep cells
alive. Their programming for specific tasks is partly
About the Author
Dr. Steven Pelech is the
Founder, President, and
Chief Scientific Officer of
Kinexus Bioinformatics
Corporation, and
concurrently a full professor
in the Department of
Medicine at the University
of British Columbia. He was
formerly the founder and
president of Kinetek
Pharmaceuticals. He has
authored more than 230
scientific papers and created
the SigNET on-line
Knowledge-bank. Seasoned
with over twenty-five yearsof
experience in the areas of
science, business, and
administration, he has
contributed leadership,
vision, and strategic planning
to Kinexus.
ExclusiveView
December 2018 35

38. hardwired into the structures of these proteins as dictated by their gene sequences. But, they are also tightly controlled by
reversible modifications after they are initially manufactured, which are added on by regulatory proteins that operate
within cellular intelligence systems.
While gene sequences can provide some clues as to the potential functions and interactions of proteins with each other
and other molecules, this information is extremely limited. Even now, we do not have a real sense of what over a third of
these diverse proteins do, and less than 20% of these proteins have received any real serious attention in research labs.
The disconnect between genetic information and the actual occurrence of disease is due to the high impact of
environmental factors such as diet, life style and exposure to agents in the environment that can affect the proteome.
Proteomes are immensely complex and dynamic. For example, blood plasma may contain as many as 40,000 different
protein products, and their individual concentrations can range over a trillion-fold. Consequently, tracking proteins offers
much better insights into the occurrence of diseases than genetic profiling, and importantly the opportunity for more
rational therapeutic intervention.
While about 21,300 genes encode proteins in the human genome, the actual number of distinct protein entities in the
proteome may actually exceed several million, largely due to the range and degree of added modifications and other
processing. More than 50 types of modifications have been documented in proteins, with phosphorylation as the
predominant reversible regulatory mechanism. Over 85% of the proteome is known to be phosphorylatable at over
250,000 sites, but the actual number of phosphosites appears to be closer to a million. The occurrence of these and other
modifications in proteins represent a rich source of biomarkers that may correlate better with the development of
pathologies.
Most sites of known protein modification were originally revealed by mass spectrometry (MS). However, apart from
being very expensive, MS requires milligram amount of biological sample material and is finicky for reliable detection
of desired target proteins. For example, out of some 3000 phosphosites in proteins that have been well documented to be
functionally important in the scientific literature, about 22% have not been reported in any MS studies, whereas another
16% were documented in only one of thousands of MS analyses that had been performed.
Antibodies have been well proven to be reliable and effective probes for the detection and quantification of specific
proteins for their present and modification states. Over a million different antibodies against diverse proteins are
presently commercially available. Furthermore, the printing of antibodies as individual microdots on microscope slide-
sized chips with densities exceeding 5000 spots per chip has paved the way for biomarker discovery that is easily
translatable into the development of routine diagnostic tests. Biomarker antibodies can readily be re-deployed into other
tried and true platforms such as immunoblotting, ELISA, and immunohistochemistry.
Problems with sample preparation, high background issues, and low sensitivity of detection initially hampered the wide-
spread adoption of antibody microarrays. However, recent breakthroughs on all of these fronts have poised antibody
microarrays to become the most versatile, reproducible, and cost-effective tools in the foreseeable future for biomarker
discovery, using as little as 25 microgram amounts of protein samples from crude, unfractionated lysates from cells,
tissues, and bio fluids. High content antibody microarrays can identify the most appropriate and robust panel of
biomarkers. When used to probe lysate microarrays printed instead with hundreds of patient specimen samples on each
slide, these biomarker antibodies can provide accurate, comprehensive and economical diagnoses for diseases and for
the monitoring of the effectiveness of therapeutic treatments.
| December 201836

40. THEDYNAMICS
Factors
OF
Social
INFLUENCINGPhysical
herearemanyfactorsthat
account for a person’s
Twell-being. One of the
factors among these can be a
person’s genes or his/her
biology. The second factor is the
individual’ s behavior. This
behavior includes whether a
person smokes or not, his/her
eating habits, and exercise
routine. There is a common
misconception amongst people that
theirhealthisaresultoftheir genes,t
h e i r v i s i t t o t h e physicians, and
their behavior. But it’s not just how
they live or healthy they are, the
social and physical environment can
havea hugeimpactonthehealthtoo.
| December 201838

41. EDUCATION
An education level can affect the health meter of a person. Education
provides the tool to make a good decision about health. It is generally
said that people with a good education will live more. They are more
likely to take part in seeing their physicianand keeping aregularhabitof
exercising. Education further helps them in eliminating unhealthy habits
like smoking and drug use. Moreover, they can avail themselves with
the benefits of health insurance alongside making connections with
theotherpeople intheirlife.All thesefactorsadd uptothe bettermentof
thehealth.
CULTURE DIFFERENCES
Different types of culture and society value body types in different
ways. In some places, the weight is seen as a positive thing where the
food is scarce and some culture despise it and label it as obesity. The
type of food one consumes can affect the health and well-being of an
individual. The cultureandthe typesoffoodsthatcommunityholdsalso
affect the health and longevity. Not only the eating patterns play a part,
but also the attitude and behavior of people play an important role,
which influences health. Such cultural traditions can induce stress in
individuals and they can doubt themselves whether they are socially
accepted and acknowledged in their life. All these factors add to the
socialinsecuritiesandirregulareatinghabits inhumanbeings.
December 2018 39
Editor’sPick
LACKOF PHYSICAL INACTIVITY
Physical inactivity among teenagers can contribute to
cardiovascular diseases, osteoporosis, or cancer in the later life
alongside increased body mass index and obesity. An
environment that restricts physical activity has been labeled as a major
factor for obesity. The rise of obesity in young people has been
attributedto environmental changes.These changes includetheuseof
transport for commute and a decrease in the opportunities for
recreationalphysicalactivities.

42. PARENTING
The health impact of good early development and education can last
a lifetime. This good start in life comes from the support of the
parents. Studies have shown that the foundations of healthy adult
life are established in early childhood and even before birth.
Parenting with slow growth and poor emotional support can lead to
the lifetime risk of poor health and reduce physical and emotional
functioning in adult years. Any kind of inferior experience and slow
growth can be embed in the biology of the child during the process
of development and can form the basis of individual biological
damage which in turn affects the health throughoutlife.
As faras children areconcerned, their emotional, cognitive, and
sensory input program brain’s responses and insecure attachment andpoorupbringingcanleadtoreduced
studyingabilitiesinschool,lowattainmentof education, andbehavior problems.Additionally,peerandfamilies
oftensethealthhabitsofyoung one such as exercising, sensible eating,refraining fromdrugs,smoking, and
alcohol. Hence, the
experienceofaninfantisalsoimportantforadulthealth.
REVENUE
People with higher income tend to be healthier and they enable
themselves to live in a safe neighborhood and have more access to
healthfoods andorganicstores.Theyalso get the access of gym,yoga
and even joggers’ park. On the other hand, citizens with lower income
are likely to live in the poverty. These include the unsafe housing,
challenges in getting healthy food, and less time for the physical
activities. Furthermore, the citizens below the poverty line can also
face challenges in availing healthcare facilities like health
insurance. It also denies people access to housing, education,
transport, and other factors to the overall participation in life. The stress
of living in poverty is even more harmful during the pregnancy and for
thebabies,children,andelders.
All these factors play an important role in a person's health on a daily basis. Individuals must understand how
these factors affectthe health so thatthey cantakethe necessary steps to improve themselves and also improve
theirhealth.
40 | December 2018

44. Headquartered in Boston, MA, UbiCare is a
prominent patient engagement company that
impacts care cost and quality through its proven
SAAS products. Effectively, UbiCare combines targeted,
evidence-based, multimedia content with a dynamic
software platform that allows complete customization and
real-time usage data.
Founded in 2002, UbiCare is on the forefront of creating a
completely digital patient engagement solution in the U.S.
In its initial stages, the company used technology to
overcome obstacles in successfully engaging and educating
patients. Through weekly, relevant emails delivered
throughout the whole episode of care, hospitals strengthen
their patient connection and relationships, enjoy immediate
patient access, and provide the means to make patients true
in their care.
Magnificent Talent
The CEO, Betsy Weaver, has gathered a team of great
talent, most of whom have been with the company for half a
decade or more—including three team members who
worked together in her last company. The Executive VP of
Content/UI/Product started out in print, adapted quickly to
the web and has since moved into mobile and interactive.
The Executive VP of Corporate previously designed
museum exhibits and applied her MBA at digitalmarketing
companies, focusing on using content to gain audience
attention, being hyper-relevant, and increase product use.
The Executive VP of Finance and Operations keeps the
team moving forward with grace and efficiency. Lastly, the
CTO, who was previously a member of the team that
created eINK used in the Amazon Kindle devices,continues
to innovate for patients and the hospitals who care for them.
Teamwork, Unity Brings Strength
“Our evolutionary—or revolutionary!—content and
UbiCare
Enhancing Care Quality by
Fostering PatientEngagement
BetsyWeaver
CEO
42 | December 2018

45. “We give
healthcarethe
tools toimprove
careand
lowercosts
platform would not have been possible without ourtalented
team,” says Betsy, proudly. This team is enhanced through
in-house continuing education with “UbiUniversity”
sessions, as well as external learning opportunities. For
example, the company’s product manager participated in a
development course to increase productivity and efficiency
with product engineers. Plus, each quarter, the whole
company bonds together by volunteering for local
community organizations.
UbiCare believes that “Patient Engagement is a ‘team-
sport’! We all need the patients, but it’s the patient
engagement provider who is the MVP,” Betsy says.
The organization’s core mission is to give healthcare
providers the means to access and sustain the connection
with the patients. “It’s not just about the means of
connection—emails, text, apps, websites or patient
portals—it’s about NO barriers to access. It’s about making
it easy, relevant and delightful, with connections that are of
use right now because they’re perfectly timed, arriving
when and where they’re needed,” asserts Betsy.
Cutting-edge Services
UbiCare’s unique platform automatically delivers turnkey
sourced, evidence-based content, providing the right
message to the right patient at the right time throughout an
entire episode of care. The cloud-based platform has been
enhanced as technology has evolved and patient and
provider needs have changed. It is now interoperable with
other hospital IT systems and meets enterprise-wide needs
for hospital systems. UbiCare’s flagship product, SmarteXp,
was first developed for the Obstetrics/Pediatrics population.
One client appreciates UbiCare for its services and noted
that expectant and new moms “are the frontend of our
customer pipeline, as they make 80% of all care decisions
for the whole family. When loyal and engaged, their value
lasts for 20+ years. UbiCare enhances that for us. They
created the digital category.”
Words about Ideal Leadership
As UbiCare’s leader, Betsy believes that “the ideal leader
is an innovator, a change agent, and a disruptor. He/She is
driven, comfortable with rapid change and able to harness
that to positive ends for the company but also for the world.
New talent and the best talent want more than money and
equity. They want to believe, grow and change with the
products and the company. The ideal leader guides and
appreciates this. Plus, good leaders must feel comfortable
moving and bringing their team along with them. This is
impossible without careful selection of the right team and
having that evolve as your innovations do. Talent evolves,
as products and the marketplace do.”
Upcoming Plans
In 2018, UbiCare completed a study with a four-hospital
system in the Midwest. It has given it and the healthcare
industry new knowledge of this type of digital connection.
When utilized from well before to well after an episode of
care, it can provide statically significant and clinically
impactful results. In this case, reduced the length of hospital
stay and decreased emergency department visits within 30
days post-operation. It also showed positive direction for
the other tracked outcome variables including the day of
surgery cancellations, discharge destination, and hospital
readmissions within 30 days post-op.
Today, the challenge ahead of the company is to share these
findings more widely to stimulate more research and to
have more patients and hospitals benefit from this research.
“Our goal is to stay armed with the findings that digitally
connecting with patients throughout a care episode works
to reduce costs and increase care quality. We want to help
providers achieve the highest ROI while improving
outcomes,” concludes Betsy.
ENGAGEMENT
So
l
Th
e
10PATIENT
LEADING
SoutionProviders2018
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December 2018 43