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EEG
DR. JAMES M. ALO, RN,MAN,MAP, PHD
Agenda
• Introduction.
• History.
• Neural Activities.
• Action Potentials.
• EEG Generation.
• Brain Rhythms.
• EEG Recording and Measurement.
   • Conditioning the Signals.
• Abnormal EEG Patterns.
• Ageing.
• Mental Disorders.
            drjma
Agenda
• Introduction.
• History.
• Neural Activities.
• Action Potentials.
• EEG Generation.
• Brain Rhythms.
• EEG Recording and Measurement.
   • Conditioning the Signals.
• Abnormal EEG Patterns.
• Ageing.
• Mental Disorders.
           drjma
Introduction
• The human brain activity start between 4-5
  months before parental development.
• The human brain represent the brain
  functional side to side the status of the
  whole body.
• EEG signals measured from the brain of a
  human.
• The medium defines the path from
  neurons, as so called signal sources to
  electro nodes which are the sensors.


           drjma
Note :-

      studying neural functions and
neurophysicological properties of the brain
together with the mechanisms underlying
the generation of the signals for detection,
diagnosis and treatment of brain disorders
and the related diseases.




          drjma
Agenda
• Introduction.
• History.
• Neural Activities.
• Action Potentials.
• EEG Generation.
• Brain Rhythms.
• EEG Recording and Measurement.
   • Conditioning the Signals.
• Abnormal EEG Patterns.
• Ageing.
• Mental Disorders.
            drjma
History
• Carlo Matteucci (1811–1868) and Emil Du
  Bois-Reymond (1818–1896) were the first
  people to register the electrical signals
  emitted from muscle nerves using a
  galvanometer and established the concept
  of neurophysiology.
• Analysis of EEG signals started during the
  early days of EEG measurement. Berger
  assisted by Dietch (1932) applied Fourier
  analysis to EEG sequences.


           drjma
Central Nervous System (CNS) contains of
two types from cells:-
  1. Nerve Cell.
  2. glia Cell.




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 Nerve Cell :-
                  it consists of

    Axons                Dendrites   Cell Bodies




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Nerve cell components
(1) Axons :-
    Is along cylinder.
    Transmits an electrical impulse and
       can be several meters long in
       vertebrates.
    In animals can be several meters but
       in humans the length can be a
       percentage of millimeter to a meter .
     An axonal transport system for
      delivering proteins to the ends of the
      cell exists and the transport system has
      ‘molecular motors’, which ride upon
             drjma
      tubulin rails.
(2) Dendrites :-
    Are connected to the axons or
     dendrites of other cells.
    1 nerve cell connected 10,000 other
     nerve cells.




              drjma
Nerve                Nerve       Nerve
   1                    2           3


                impulses


                 dendrites


                 connects


Dendrites 1           Dendrites   Dendrites
                         2           3




              drjma
Agenda
• Introduction.
• History.
• Neural Activities.
• Action Potentials.
• EEG Generation.
• Brain Rhythms.
• EEG Recording and Measurement.
   • Conditioning the Signals.
• Abnormal EEG Patterns.
• Ageing.
• Mental Disorders.
            drjma
Neural Activities
A potential of 60–70 mV with negative polarity may be
recorded under the membrane of the cell body.
 This potential changes:-
     If an action potential travels along the fibre,
      which ends in an excitatory synapse, an
      excitatory postsynaptic potential (EPSP) occurs
      in the following neuron.
     If two action potentials travel along the same
      fibre over a short distance, there will be a
      summation of EPSPs producing an action
      potential on the postsynaptic neuron providing a
      certain threshold of membrane potential is
      reached.

             drjma
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Note

  With observation :-
      EEG + DC potentials = Abnormalities in the
      brain.
  DC component:- long strings of zeros or ones.




                     drjma
Agenda
• Introduction.
• History.
• Neural Activities.
• Action Potentials.
• EEG Generation.
• Brain Rhythms.
• EEG Recording and Measurement.
   • Conditioning the Signals.
• Abnormal EEG Patterns.
• Ageing.
• Mental Disorders.
            drjma
Action Potentials (AP)

• APs are caused by an exchange of ions
  across the neuron membrane and an AP is
  a temporary change in the membrane
  potential that is transmitted along the
  axon.
• The conduction velocity of action
  potentials lies between 1 and 100 m/s.
  APs are initiated by many different types of
  stimuli; sensory nerves respond to many
  types of stimuli, such as chemical, light,
  electricity, pressure, touch, and stretching.

           drjma
Action potentials processes
1. The action must be more than gate
   threshold value.
2. Depolarization .
3. Sodium gates close.
4. Potassium gates open.
5. Repolarization.
6. Hyperpolarization.




          drjma
EEG Generation
 EEG signal is measured of current flow of
  dendrites of neurons in cerebral context.

 Brain cells active mode (get a new action
  potential), the cell produced within dendrites
  so this current generate a magnetic field
  (EMG) that cover over scalp.

 By the anatomical of the human head we
  found that it consists of three main layers.

• 1-scalp

• 2-skull   drjma
Brain Rhythms
  Brain rhythms is depend on EEG
   signals .
  The amplitudes and frequencies of
   such signals change from one to
   another.
  This waves from low to high (alpha ,
   theta, beta ,delta ,gamma)
  The history about found this
   frequencies.
  Draft that show the frequencies' of this
   signals.(figure 1.7)
          drjma
drjma
Agenda
• Introduction.
• History.
• Neural Activities.
• Action Potentials.
• EEG Generation.
• Brain Rhythms.
• EEG Recording and Measurement.
   • Conditioning the Signals.
• Abnormal EEG Patterns.
• Ageing.
• Mental Disorders.
            drjma
EEG Recording and
                Measurement
                         Signal

EEG                      FMRI                MEG

        • EEG :- Electroencephalogram.
        • FMRI:- Functional Magmatic
                   Resonance imaging.
        • MEG:- Magnetoencephalogram.
  The functional and physiological changes within
   brain can registered by EEG,MEG and FMRI.

                 drjma
The reasons of not using FMRI
    about using EEG,MEG
1) Time resolution of FMRI image is very low
   (2 frames/sec).EEG bandwidth can be
   viewed using EEG or MEG signal.
2) Many types of mental activities brain
   disorders cannot be registered using
   FMRI.
3) Accessibility of FMRI systems is limited
   and costly.




           drjma
EEG system consists of

Electrodes   Amplifiers           Filters     Needle


 To convert from analog signal to digital signal:-
                  1) Sampling.
                  2) Quantization.
                 3) Encoding.




                          drjma
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Characteristics of EEG signal:-
   Note


If data volume is increased then the
   number of bits increase.
 Effective bandwidth of EEG signal
   approximately 100 HZ.
 Minimum frequency 200 sample/sec.
 Higher resolution (brain activities)=2000
   sample/sec.
         1 sample        16 bit

          drjma
Note

 Although the format of reading the EEG data may be different for
 different EEG machines, these formats are easily convertible to
 spreadsheets readable by most signal processing software packages
 such as MATLAB.




                            drjma
Different types of electrodes:-
1) Disposable (gel-less, and pre-gelled
   types).
2) Reusable dice electrodes (gold ,silver,
   stainless steel or tin).
3) Headbands and electrode caps.
4) Saline based electrodes.
5) Needle electrodes.

 For multichannel recordings with a large
  number of electrodes, electro caps are
  often used.
           drjma
Conditioning the signals
• The row EEG signal have amplitudes of
  order of micro volts and contain frequency
  components up to 300 HZ.




           drjma
Filters
• Are used to make suitable for processing
   and visualization.
Is divided to:-
1) High pass filter:-
            remove distributing very low
            frequency components.
2) Low pass filter:-
            remove distributing very high
            frequency components.


           drjma
Categories abnormal EEG
patterns:-
 Widespread intermitted slow wave
  abnormalities.
 Bilateral persistent EEG.
 Focal persistent EEG.




          drjma
1) Widespread intermitted slow wave abnormalities:-

• which is attenuated by alerting the individual and
   eye opening, and accentuated with eye closure,
   hyperventilation, or drowsiness.
2) Bilateral persistent EEG:-
• the phenomenon in different stages of impaired,
   conscious:-
3) Focal persistent EEG:-
• these abnormalities may be in the form of distortion
   and disappearance of normal patterns, appearance
   and increase of abnormal patterns, or
   disappearance of all patterns, but such changes
   are seldom seen at the cerebral cortex.


             drjma
Agenda
• Introduction.
• History.
• Neural Activities.
• Action Potentials.
• EEG Generation.
• Brain Rhythms.
• EEG Recording and Measurement.
   • Conditioning the Signals.
• Abnormal EEG Patterns.
• Ageing.
• Mental Disorders.
            drjma
Ageing
• The ageing process affects the normal
  cerebral activity in waking and sleep, and
  changes the response of the brain to
  stimuli.
• The charges stem from reducing the
  number of neurons and due to a general
  change in the brain pathology.
• General cause for ageing of brain may be
  decrease in cerebral blood flow.
• The REM duration decrease during the
  night.
• Dementia increases dramatically with
           drjma
  ageing.
Agenda
• Introduction.
• History.
• Neural Activities.
• Action Potentials.
• EEG Generation.
• Brain Rhythms.
• EEG Recording and Measurement.
   • Conditioning the Signals.
• Abnormal EEG Patterns.
• Ageing.
• Mental Disorders.
            drjma
Mental Disorders
• Is divided to


Dementia            Epileptic     Psychiatric
                   Seizure and    Disorders
                   No epileptic
                     attacks


                     External
                     Effects




           drjma
1) Dementia
• Dementia is a syndrome that consists of a
  decline in intellectual and cognitive
  abilities this consequently affects the
  normal social activities, mode, and the
  relationship and interaction with other
  people. EEG is often used to study the
  effect of dementia; EEG signal can be
  used to detect the abnormality.
Dementia is classified into
    Cortical dementia such as Alzheimer's
     disease (AD).
    Sub cortical dementia forms such as
     Parkinson's.
             drjma
 Generally
       Sub cortical dementias introduce less abnormality to
         the EEG patterns than the cortical ones.
       EEG is usually used in the diagnosis and evaluation
         of many cortical and sub cortical.




                        drjma
2) Epileptic Seizure and Non-
epileptic Attacks
• Often the onset of a clinical seizure is
  characterized by a sudden change of
  frequency in the EEG measurement.
• The abnormalities may be due to
  psychogenic changes, variations in body
  metabolism or circulstory insufficiency.
  The most important ones are periodic or
  quasi-periodic discharges related to serve
  CNS diseases.



           drjma
• Despite the epileptic form signals there are spikes
  and other paroxysmal discharges in healthy non
  epileptic persons. These discharges may be found
  in healthy individuals without any other symptoms
  of diseases. They may appear during periods of
  particular mental challenge on individuals, such as
  soldiers in the war front line, pilots, and prisoners.




                    drjma
3) Psychiatric disorders.
• Not only can functional and
  certain anatomical brain
  abnormalities be investigated
  using EEG signals,
  pathophysiological brain
  disorders can also be studied
  by analysing such signals.


        drjma
4)External Effects

  EEG signal patterns may significantly
  change when using drugs for the treatment
  and suppression of various mental and CNS
  abnormalities. Variations in EEG patterns
  may also arise by just looking at the TV
  screen or listening to music without any
  attention. However, among the external
  effects the most significant ones are the
  pharmacological and drug effects.
  Therefore, it is important to know the effects
  of these drugs on the changes of EEG
Test        Purpose             Preparation               Post- Nursing
                                                                 Care
ElectroEnc   Record        Explain procedure                Help client
ephaloGra    electrical    Done by technician in a quiet    remove paste
m            activity of   room                             from hair
             brain         Painless                         Admin prescribed
                           Tranquilizer & stimulant meds    meds w/held b4
                           w/held for 24-48 hrs pre-EEG     EEG
                           Maybe ask to hyperventilate 3-   Observe for
                           4 mins and watch bright,         seizure activity in
                           flashing light                   seizure prone
                           Meals not w/held                 patients.
                           Kept awake night b4 test




                                    drjma
“Learners’ are learning from experiences they have experienced which cannot
     be taught by teachers except themselves.”- Dr. James M. Alo




                          Shockran!

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Eeg basics.drjma

  • 1. EEG DR. JAMES M. ALO, RN,MAN,MAP, PHD
  • 2. Agenda • Introduction. • History. • Neural Activities. • Action Potentials. • EEG Generation. • Brain Rhythms. • EEG Recording and Measurement. • Conditioning the Signals. • Abnormal EEG Patterns. • Ageing. • Mental Disorders. drjma
  • 3. Agenda • Introduction. • History. • Neural Activities. • Action Potentials. • EEG Generation. • Brain Rhythms. • EEG Recording and Measurement. • Conditioning the Signals. • Abnormal EEG Patterns. • Ageing. • Mental Disorders. drjma
  • 4. Introduction • The human brain activity start between 4-5 months before parental development. • The human brain represent the brain functional side to side the status of the whole body. • EEG signals measured from the brain of a human. • The medium defines the path from neurons, as so called signal sources to electro nodes which are the sensors. drjma
  • 5. Note :- studying neural functions and neurophysicological properties of the brain together with the mechanisms underlying the generation of the signals for detection, diagnosis and treatment of brain disorders and the related diseases. drjma
  • 6. Agenda • Introduction. • History. • Neural Activities. • Action Potentials. • EEG Generation. • Brain Rhythms. • EEG Recording and Measurement. • Conditioning the Signals. • Abnormal EEG Patterns. • Ageing. • Mental Disorders. drjma
  • 7. History • Carlo Matteucci (1811–1868) and Emil Du Bois-Reymond (1818–1896) were the first people to register the electrical signals emitted from muscle nerves using a galvanometer and established the concept of neurophysiology. • Analysis of EEG signals started during the early days of EEG measurement. Berger assisted by Dietch (1932) applied Fourier analysis to EEG sequences. drjma
  • 8. Central Nervous System (CNS) contains of two types from cells:- 1. Nerve Cell. 2. glia Cell. drjma
  • 9.  Nerve Cell :- it consists of Axons Dendrites Cell Bodies drjma
  • 10. drjma
  • 11. Nerve cell components (1) Axons :-  Is along cylinder.  Transmits an electrical impulse and can be several meters long in vertebrates.  In animals can be several meters but in humans the length can be a percentage of millimeter to a meter .  An axonal transport system for delivering proteins to the ends of the cell exists and the transport system has ‘molecular motors’, which ride upon drjma tubulin rails.
  • 12. (2) Dendrites :-  Are connected to the axons or dendrites of other cells.  1 nerve cell connected 10,000 other nerve cells. drjma
  • 13. Nerve Nerve Nerve 1 2 3 impulses dendrites connects Dendrites 1 Dendrites Dendrites 2 3 drjma
  • 14. Agenda • Introduction. • History. • Neural Activities. • Action Potentials. • EEG Generation. • Brain Rhythms. • EEG Recording and Measurement. • Conditioning the Signals. • Abnormal EEG Patterns. • Ageing. • Mental Disorders. drjma
  • 15. Neural Activities A potential of 60–70 mV with negative polarity may be recorded under the membrane of the cell body.  This potential changes:-  If an action potential travels along the fibre, which ends in an excitatory synapse, an excitatory postsynaptic potential (EPSP) occurs in the following neuron.  If two action potentials travel along the same fibre over a short distance, there will be a summation of EPSPs producing an action potential on the postsynaptic neuron providing a certain threshold of membrane potential is reached. drjma
  • 16. drjma
  • 17. Note With observation :- EEG + DC potentials = Abnormalities in the brain. DC component:- long strings of zeros or ones. drjma
  • 18. Agenda • Introduction. • History. • Neural Activities. • Action Potentials. • EEG Generation. • Brain Rhythms. • EEG Recording and Measurement. • Conditioning the Signals. • Abnormal EEG Patterns. • Ageing. • Mental Disorders. drjma
  • 19. Action Potentials (AP) • APs are caused by an exchange of ions across the neuron membrane and an AP is a temporary change in the membrane potential that is transmitted along the axon. • The conduction velocity of action potentials lies between 1 and 100 m/s. APs are initiated by many different types of stimuli; sensory nerves respond to many types of stimuli, such as chemical, light, electricity, pressure, touch, and stretching. drjma
  • 20. Action potentials processes 1. The action must be more than gate threshold value. 2. Depolarization . 3. Sodium gates close. 4. Potassium gates open. 5. Repolarization. 6. Hyperpolarization. drjma
  • 21. EEG Generation  EEG signal is measured of current flow of dendrites of neurons in cerebral context.  Brain cells active mode (get a new action potential), the cell produced within dendrites so this current generate a magnetic field (EMG) that cover over scalp.  By the anatomical of the human head we found that it consists of three main layers. • 1-scalp • 2-skull drjma
  • 22. Brain Rhythms Brain rhythms is depend on EEG signals . The amplitudes and frequencies of such signals change from one to another. This waves from low to high (alpha , theta, beta ,delta ,gamma) The history about found this frequencies. Draft that show the frequencies' of this signals.(figure 1.7) drjma
  • 23. drjma
  • 24. Agenda • Introduction. • History. • Neural Activities. • Action Potentials. • EEG Generation. • Brain Rhythms. • EEG Recording and Measurement. • Conditioning the Signals. • Abnormal EEG Patterns. • Ageing. • Mental Disorders. drjma
  • 25. EEG Recording and Measurement Signal EEG FMRI MEG • EEG :- Electroencephalogram. • FMRI:- Functional Magmatic Resonance imaging. • MEG:- Magnetoencephalogram. The functional and physiological changes within brain can registered by EEG,MEG and FMRI. drjma
  • 26. The reasons of not using FMRI about using EEG,MEG 1) Time resolution of FMRI image is very low (2 frames/sec).EEG bandwidth can be viewed using EEG or MEG signal. 2) Many types of mental activities brain disorders cannot be registered using FMRI. 3) Accessibility of FMRI systems is limited and costly. drjma
  • 27. EEG system consists of Electrodes Amplifiers Filters Needle To convert from analog signal to digital signal:- 1) Sampling. 2) Quantization. 3) Encoding. drjma
  • 28. drjma
  • 29. Characteristics of EEG signal:- Note If data volume is increased then the number of bits increase.  Effective bandwidth of EEG signal approximately 100 HZ.  Minimum frequency 200 sample/sec.  Higher resolution (brain activities)=2000 sample/sec. 1 sample 16 bit drjma
  • 30. Note Although the format of reading the EEG data may be different for different EEG machines, these formats are easily convertible to spreadsheets readable by most signal processing software packages such as MATLAB. drjma
  • 31. Different types of electrodes:- 1) Disposable (gel-less, and pre-gelled types). 2) Reusable dice electrodes (gold ,silver, stainless steel or tin). 3) Headbands and electrode caps. 4) Saline based electrodes. 5) Needle electrodes.  For multichannel recordings with a large number of electrodes, electro caps are often used. drjma
  • 32. Conditioning the signals • The row EEG signal have amplitudes of order of micro volts and contain frequency components up to 300 HZ. drjma
  • 33. Filters • Are used to make suitable for processing and visualization. Is divided to:- 1) High pass filter:- remove distributing very low frequency components. 2) Low pass filter:- remove distributing very high frequency components. drjma
  • 34. Categories abnormal EEG patterns:-  Widespread intermitted slow wave abnormalities.  Bilateral persistent EEG.  Focal persistent EEG. drjma
  • 35. 1) Widespread intermitted slow wave abnormalities:- • which is attenuated by alerting the individual and eye opening, and accentuated with eye closure, hyperventilation, or drowsiness. 2) Bilateral persistent EEG:- • the phenomenon in different stages of impaired, conscious:- 3) Focal persistent EEG:- • these abnormalities may be in the form of distortion and disappearance of normal patterns, appearance and increase of abnormal patterns, or disappearance of all patterns, but such changes are seldom seen at the cerebral cortex. drjma
  • 36. Agenda • Introduction. • History. • Neural Activities. • Action Potentials. • EEG Generation. • Brain Rhythms. • EEG Recording and Measurement. • Conditioning the Signals. • Abnormal EEG Patterns. • Ageing. • Mental Disorders. drjma
  • 37. Ageing • The ageing process affects the normal cerebral activity in waking and sleep, and changes the response of the brain to stimuli. • The charges stem from reducing the number of neurons and due to a general change in the brain pathology. • General cause for ageing of brain may be decrease in cerebral blood flow. • The REM duration decrease during the night. • Dementia increases dramatically with drjma ageing.
  • 38. Agenda • Introduction. • History. • Neural Activities. • Action Potentials. • EEG Generation. • Brain Rhythms. • EEG Recording and Measurement. • Conditioning the Signals. • Abnormal EEG Patterns. • Ageing. • Mental Disorders. drjma
  • 39. Mental Disorders • Is divided to Dementia Epileptic Psychiatric Seizure and Disorders No epileptic attacks External Effects drjma
  • 40. 1) Dementia • Dementia is a syndrome that consists of a decline in intellectual and cognitive abilities this consequently affects the normal social activities, mode, and the relationship and interaction with other people. EEG is often used to study the effect of dementia; EEG signal can be used to detect the abnormality. Dementia is classified into  Cortical dementia such as Alzheimer's disease (AD).  Sub cortical dementia forms such as Parkinson's. drjma
  • 41.  Generally  Sub cortical dementias introduce less abnormality to the EEG patterns than the cortical ones.  EEG is usually used in the diagnosis and evaluation of many cortical and sub cortical. drjma
  • 42. 2) Epileptic Seizure and Non- epileptic Attacks • Often the onset of a clinical seizure is characterized by a sudden change of frequency in the EEG measurement. • The abnormalities may be due to psychogenic changes, variations in body metabolism or circulstory insufficiency. The most important ones are periodic or quasi-periodic discharges related to serve CNS diseases. drjma
  • 43. • Despite the epileptic form signals there are spikes and other paroxysmal discharges in healthy non epileptic persons. These discharges may be found in healthy individuals without any other symptoms of diseases. They may appear during periods of particular mental challenge on individuals, such as soldiers in the war front line, pilots, and prisoners. drjma
  • 44. 3) Psychiatric disorders. • Not only can functional and certain anatomical brain abnormalities be investigated using EEG signals, pathophysiological brain disorders can also be studied by analysing such signals. drjma
  • 45. 4)External Effects EEG signal patterns may significantly change when using drugs for the treatment and suppression of various mental and CNS abnormalities. Variations in EEG patterns may also arise by just looking at the TV screen or listening to music without any attention. However, among the external effects the most significant ones are the pharmacological and drug effects. Therefore, it is important to know the effects of these drugs on the changes of EEG
  • 46. Test Purpose Preparation Post- Nursing Care ElectroEnc Record Explain procedure Help client ephaloGra electrical Done by technician in a quiet remove paste m activity of room from hair brain Painless Admin prescribed Tranquilizer & stimulant meds meds w/held b4 w/held for 24-48 hrs pre-EEG EEG Maybe ask to hyperventilate 3- Observe for 4 mins and watch bright, seizure activity in flashing light seizure prone Meals not w/held patients. Kept awake night b4 test drjma
  • 47. “Learners’ are learning from experiences they have experienced which cannot be taught by teachers except themselves.”- Dr. James M. Alo Shockran!

Notas del editor

  1. EEG or MEG (magneto encephalogram) machines may be integrated with other neuroimaging systems such as functional magnetic resonance imaging (fMRI).