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Applied Ethics
     and
 Neuroethics
Applied Ethics
• “Applied ethics” – a separate discipline from
  pure or philosophical ethics?
• Fill-in-the-blank ethics:
  – Business ethics
  – Legal ethics
  – Environmental ethics
  – Bioethics
Bioethics case 1
Baby Boy B is a patient in the NICU. He was born immature and developed
   multiple complications of prematurity, including respiratory failure requiring
   mechanical ventilation. He also developed multi-organ system failure and a
   large intracranial hemorrhage, but he was not technically brain dead. His
   prognosis was extremely poor and, after one week of aggressive care, the
   NICU staff persuaded his parents that withdrawal of life support was in his
   best interests. So today the NICU staff wrote an order for the patient to be
   removed from the ventilator and extubated. After extubation, he would be
   treated with sedatives (which he was already receiving). However, the NICU
   nurse tells the NICU doctor that Baby Boy B is not moving anything, most
   likely since, just 1 hour ago, he got a dose of a paralytic (given when someone
   is on a ventilator). Because of his multi-organ system failure, however, the
   effect of the paralytic will be irreversible for quite a long time and could last
   for perhaps 1 – 2 days or even longer. The parents are telling the NICU nurses
   and doctors that they want their preference carried out immediately: remove
   their baby from the machines and let him die in peace. The NICU has no
   empty beds but has two neonates at other hospitals on a waiting list with
   potentially treatable conditions if they were transferred to this hospital’s
   NICU. The NICU staff refuses to remove the baby from the ventilator while
   still paralyzed since they say that doing so would constitute euthanasia.
Bioethics case 2
A premature baby has severe intracranial
  hemorrhage and meets clinical criteria for
  “brain death.” The NICU team wants to
  confirm the diagnosis by having tests done
  since the parents refuse to believe that their
  baby is dead. The parents refuse to give
  permission for the test. Plus they state that
  even if the death showed no blood circulation,
  they would not allow the ventilator to be
  removed from their child.
Bioethics case 3
A 75-year-old woman is admitted to the ICU with ascending
   paralysis due to acute Guillain-Barre Syndrome (GBS). She
   got emergently intubated and ventilated upon arrival, and
   then treated with plasma exchange. Based on the EMG
   results, the neurologist thinks her prognosis for full
   recovery is excellent. Her pre-hospital state was excellent,
   e.g., she was totally lucid and functional in all respects in
   her own home. However, she’s got an ICU psychosis, which
   is extremely upsetting to her daughter. The daughter feels
   her mother is being tortured and that the ventilator should
   be removed to end her suffering. The mother gave her
   daughter the Durable Power of Attorney for Health Affairs.
Bioethics case 4
An 80-year-old woman got a high-risk open-heart procedure and has
   been on the ventilator for 3 weeks post-operatively. The team is
   not able to wean her off the machine; in fact, she’s getting worse
   slowly and her prognosis for recovery was poor. She’s heavily
   sedated and unable to express her wishes. She has a valid living will
   that expressly mentioned chronic ventilator dependency as
   something she wouldn’t have wanted and she also gave her son, a
   minister, a valid Durable Power of Attorney for Health Affairs. The
   son confers with all the family members and makes the decision to
   ask that his mother be removed from the ventilator, made
   comfortable, and allowed to die. Unfortunately, her attending
   surgeon refused the son’s request. (You had heard rumors of some
   surgeons in the hospital, who delayed removal of life-support for 30
   days post-op so that it wouldn’t be counted as an operative death
   and thus not stain their record).
Applied Ethics
• “Applied ethics” – a separate discipline from
  pure or philosophical ethics?
• Fill-in-the-blank ethics:
  – Business ethics
  – Legal ethics
  – Environmental ethics
  – Bioethics
  – Neuroethics
Neuroethics
• What neuroscientists should and shouldn’t do
• What people should and shouldn’t do with
  neurotechnologies
• How the “neuroscience worldview” affects
  how we think about, and treat, each other

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Lecture 2

  • 1. Applied Ethics and Neuroethics
  • 2. Applied Ethics • “Applied ethics” – a separate discipline from pure or philosophical ethics? • Fill-in-the-blank ethics: – Business ethics – Legal ethics – Environmental ethics – Bioethics
  • 3. Bioethics case 1 Baby Boy B is a patient in the NICU. He was born immature and developed multiple complications of prematurity, including respiratory failure requiring mechanical ventilation. He also developed multi-organ system failure and a large intracranial hemorrhage, but he was not technically brain dead. His prognosis was extremely poor and, after one week of aggressive care, the NICU staff persuaded his parents that withdrawal of life support was in his best interests. So today the NICU staff wrote an order for the patient to be removed from the ventilator and extubated. After extubation, he would be treated with sedatives (which he was already receiving). However, the NICU nurse tells the NICU doctor that Baby Boy B is not moving anything, most likely since, just 1 hour ago, he got a dose of a paralytic (given when someone is on a ventilator). Because of his multi-organ system failure, however, the effect of the paralytic will be irreversible for quite a long time and could last for perhaps 1 – 2 days or even longer. The parents are telling the NICU nurses and doctors that they want their preference carried out immediately: remove their baby from the machines and let him die in peace. The NICU has no empty beds but has two neonates at other hospitals on a waiting list with potentially treatable conditions if they were transferred to this hospital’s NICU. The NICU staff refuses to remove the baby from the ventilator while still paralyzed since they say that doing so would constitute euthanasia.
  • 4. Bioethics case 2 A premature baby has severe intracranial hemorrhage and meets clinical criteria for “brain death.” The NICU team wants to confirm the diagnosis by having tests done since the parents refuse to believe that their baby is dead. The parents refuse to give permission for the test. Plus they state that even if the death showed no blood circulation, they would not allow the ventilator to be removed from their child.
  • 5. Bioethics case 3 A 75-year-old woman is admitted to the ICU with ascending paralysis due to acute Guillain-Barre Syndrome (GBS). She got emergently intubated and ventilated upon arrival, and then treated with plasma exchange. Based on the EMG results, the neurologist thinks her prognosis for full recovery is excellent. Her pre-hospital state was excellent, e.g., she was totally lucid and functional in all respects in her own home. However, she’s got an ICU psychosis, which is extremely upsetting to her daughter. The daughter feels her mother is being tortured and that the ventilator should be removed to end her suffering. The mother gave her daughter the Durable Power of Attorney for Health Affairs.
  • 6. Bioethics case 4 An 80-year-old woman got a high-risk open-heart procedure and has been on the ventilator for 3 weeks post-operatively. The team is not able to wean her off the machine; in fact, she’s getting worse slowly and her prognosis for recovery was poor. She’s heavily sedated and unable to express her wishes. She has a valid living will that expressly mentioned chronic ventilator dependency as something she wouldn’t have wanted and she also gave her son, a minister, a valid Durable Power of Attorney for Health Affairs. The son confers with all the family members and makes the decision to ask that his mother be removed from the ventilator, made comfortable, and allowed to die. Unfortunately, her attending surgeon refused the son’s request. (You had heard rumors of some surgeons in the hospital, who delayed removal of life-support for 30 days post-op so that it wouldn’t be counted as an operative death and thus not stain their record).
  • 7. Applied Ethics • “Applied ethics” – a separate discipline from pure or philosophical ethics? • Fill-in-the-blank ethics: – Business ethics – Legal ethics – Environmental ethics – Bioethics – Neuroethics
  • 8. Neuroethics • What neuroscientists should and shouldn’t do • What people should and shouldn’t do with neurotechnologies • How the “neuroscience worldview” affects how we think about, and treat, each other