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Inherited Change and
  Gene Technology

The passage of information
 from parent to offspring




                             ALBIO9700/2006JK
• Locus – position on the chromosome
          in which the gene resides
            *plural: loci


• Alleles – a particular variety of the
           same gene




                                          ALBIO9700/2006JK
• Homozygous – 2 identical alleles of a
  gene

• Heterozygous – 2 different alleles of a
  gene




                                       ALBIO9700/2006JK
• Genotype – alleles possesed by an
  organism

• Phenotype – observable
  characteristics/physical traits of an
  organism (resulting from interaction
  between genotype and environment)




                                          ALBIO9700/2006JK
• Dominant – when effect on the phenotype of a
  heterozygote is identical to its effect in a
  homozygote

• Recessive – only expressed when no dominant
  allele is present

• Codominant – both alleles have an effect on
  the phenotype of a heterozygous organism




                                           ALBIO9700/2006JK
Genetic Diagram (monohybrid
                  crosses)
•   Let N be the dominant allele for normal pigment.
•   Let n be the recessive allele for albino.

Parent phenotype          Heterozygous Normal           Heterozygous
  Normal

Parent genotype                Nn                X
  Nn

Gametes                             N     n
  N   n

Possible offspring
genotype                 NN             Nn               Nn
    nn

Offspring phenotype      Normal         Normal       Normal
   Albino
                                                              ALBIO9700/2006JK
Genotypes of parent

                     N              n
                     NN                 Nn
            N
Genotypes
                   Normal           Normal
of parent
                     Nn                 nn
            n
                   Normal            Albino

            Ratio of phenotype   3 normal : 1 albino




                                                       ALBIO9700/2006JK
Genetic Diagram (dihybrid crosses)
• Let A be the dominant allele for purple stem and a
  recessive green
• Let D be the dominant allele for cut leaves and d
  recessive smooth

Parent phenotype      Heterozygous        Heterozygous

Parent genotype              AaDd          X           AaDd

Gametes                 AD           Ad          aD
    ad




                                                        ALBIO9700/2006JK
Genotypes   of parent
                    AD        Ad         aD       ad
                  AADD       AADd        AaDD      AaDd
             AD   Purple,    Purple,    Purple,   Purple,
                   cut         cut         cut       cut
                  AADd         AAdd      AaDd        Aadd
             Ad
                  Purple,     Purple,    Purple,    Purple,
 Genotype          cut        smooth      cut       potato
   s of
                  AaDD        AaDd       aaDD       aaDd
  parent
             aD   Purple,     Purple,    Green,     Green,
                   cut         cut         cut       Cut
                  AaDd         Aadd       aaDd       aadd
             ad   Purple,     Purple,    Green,     Green,
                   cut        smooth       Cut      smooth

Ratio of phenotype 9 purple,cut:3 purple,smooth:3 green,cut:1 green,smooth

                                                                ALBIO9700/2006JK
• Sex linkage – related to genes that are
  carried on an X chromosome but not on a
  Y chromosome

• Codominance ?

• Multiple alleles – the existence of 3 or
  more alleles of a gene (eg. determination
  of A, B, and O blood groups)


                                        ALBIO9700/2006JK
Test Crosses

• Involves crossing an organism showing
  the dominant phenotype with one which is
  homozygous recessive to find out if the
  dominant genotype is hetero- or
  homozygous.




                                      ALBIO9700/2006JK

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02 Passage of Info from Parent to Offspring

  • 1. Inherited Change and Gene Technology The passage of information from parent to offspring ALBIO9700/2006JK
  • 2. • Locus – position on the chromosome in which the gene resides *plural: loci • Alleles – a particular variety of the same gene ALBIO9700/2006JK
  • 3. • Homozygous – 2 identical alleles of a gene • Heterozygous – 2 different alleles of a gene ALBIO9700/2006JK
  • 4. • Genotype – alleles possesed by an organism • Phenotype – observable characteristics/physical traits of an organism (resulting from interaction between genotype and environment) ALBIO9700/2006JK
  • 5. • Dominant – when effect on the phenotype of a heterozygote is identical to its effect in a homozygote • Recessive – only expressed when no dominant allele is present • Codominant – both alleles have an effect on the phenotype of a heterozygous organism ALBIO9700/2006JK
  • 6. Genetic Diagram (monohybrid crosses) • Let N be the dominant allele for normal pigment. • Let n be the recessive allele for albino. Parent phenotype Heterozygous Normal Heterozygous Normal Parent genotype  Nn X Nn Gametes N n N n Possible offspring genotype NN Nn Nn nn Offspring phenotype Normal Normal Normal Albino ALBIO9700/2006JK
  • 7. Genotypes of parent N n NN Nn N Genotypes Normal Normal of parent Nn nn n Normal Albino Ratio of phenotype 3 normal : 1 albino ALBIO9700/2006JK
  • 8. Genetic Diagram (dihybrid crosses) • Let A be the dominant allele for purple stem and a recessive green • Let D be the dominant allele for cut leaves and d recessive smooth Parent phenotype Heterozygous Heterozygous Parent genotype  AaDd X AaDd Gametes AD Ad aD ad ALBIO9700/2006JK
  • 9. Genotypes of parent AD Ad aD ad AADD AADd AaDD AaDd AD Purple, Purple, Purple, Purple, cut cut cut cut AADd AAdd AaDd Aadd Ad Purple, Purple, Purple, Purple, Genotype cut smooth cut potato s of AaDD AaDd aaDD aaDd parent aD Purple, Purple, Green, Green, cut cut cut Cut AaDd Aadd aaDd aadd ad Purple, Purple, Green, Green, cut smooth Cut smooth Ratio of phenotype 9 purple,cut:3 purple,smooth:3 green,cut:1 green,smooth ALBIO9700/2006JK
  • 10. • Sex linkage – related to genes that are carried on an X chromosome but not on a Y chromosome • Codominance ? • Multiple alleles – the existence of 3 or more alleles of a gene (eg. determination of A, B, and O blood groups) ALBIO9700/2006JK
  • 11. Test Crosses • Involves crossing an organism showing the dominant phenotype with one which is homozygous recessive to find out if the dominant genotype is hetero- or homozygous. ALBIO9700/2006JK