This document summarizes several human clinical studies that evaluated the effects of consuming Tahitian Noni Juice (TNJ). The studies found that drinking 2 ounces of TNJ twice daily for 1-3 months showed: 1) A reduction in free radicals and DNA damage in heavy smokers. 2) Positive effects on blood lipid profiles in heavy smokers such as decreased total cholesterol and LDL, and increased HDL. 3) Improvement in quality of life scores and reduced fatigue in post-menopausal women. 4) Reduced blood pressure in hypertensive subjects. 5) Reduced joint pain and increased mobility in subjects with cervical spondylosis.

1. TAHITIAN
NONI®
Juice
Human
Clinical
Research
© 2008 TAHITIAN NONI INTERNATIONAL

2. TAHITIAN NONI Juice delivers superior
antioxidants that help rid the body of harmful
free radicals
1. Free radicals in the blood—double-blind human clinical trial
2 fl. oz. TNJ or placebo BID for 1 month
38 smokers assigned to TNJ
30 smokers assigned to placebo
Placebo (grape & blueberry juice)—no significant
effect
TAHITIAN NONI® Juice—statistically significant
reduction in free radicals in the blood
27% reduction in SAR
23% reduction in LPO
© 2008 TAHITIAN NONI INTERNATIONAL

3. 2. MDA-DNA adduct—in lymphocytes of heavy smokers
1 or 4 fl. oz. TNJ BID for 1 month
Placebo—
305.27% increase (n=42, P<0.001)
TAHITIAN NONI® Juice—
53.36% reduction (n=203, p<0.001)
3. Aromatic-DNA adduct—in lymphocytes of heavy smokers
1 or 4 fl. oz. TNJ BID for 1 month
Placebo—
4.99% increase (n=42, P>0.05)
TAHITIAN NONI® Juice—
44.9% reduction (n=203, p<0.0001)
© 2008 TAHITIAN NONI INTERNATIONAL

4. TAHITIAN NONI Juice helps maintain
cholesterol at existing healthy levels
Lipid Profiles in heavy smokers
 38 Current Smokers drank 2 ounces of TAHITIAN
NONI® Juice twice a day for 30 days.
 30 Current Smokers drank 2 ounces of a
placebo.
 TNJ had a positive effect on blood lipid profiles.
 Placebo had no positive effect
© 2008 TAHITIAN NONI INTERNATIONAL

5. Trial Results
Decreased Increased
Total cholesterol: 7–22%
LDL: 6-10%
Triglyceride: 10-54%
Homocysteine: 21%
HDL: 10-16%
© 2008 TAHITIAN NONI INTERNATIONAL

6. Type B Lipoprotein Profile
BAD
Type A Lipoprotein Profile
GOOD
© 2008 TAHITIAN NONI INTERNATIONAL

7. Placebo
Before After: No change
© 2008 TAHITIAN NONI INTERNATIONAL

8. TAHITIAN NONI® Juice
Before After
© 2008 TAHITIAN NONI INTERNATIONAL

9. TAHITIAN NONI Juice increases energy
© 2008 TAHITIAN NONI INTERNATIONAL

10. Pilot Clinical Study in Post-
menopausal Women
University of Illinois College of Medicine
Drank 2 fl oz TNJ both morning and night for 3
months
Assessed with SF-36 clinical survey.
Results: Overall improvement in quality of life,
including physical function scores and significant
improvement in mood and well being
© 2008 TAHITIAN NONI INTERNATIONAL

11. Improvement in
Physical
Functioning Scores
© 2008 TAHITIAN NONI INTERNATIONAL

12. The QLQ-C30 used in the
University of Hawaii Study
SCALE NO YES
1. Do you have any trouble doing Physical 1 2
strenuous activities, like carrying a
heavy shopping bag or a suitcase?
2. Do you have any trouble taking a long Physical 1 2
walk?
3. Do you have any trouble take a short Physical 1 2
walk outside of the house?
4. Do have to stay in bed or a chair for Physical 1 2
most of the day?
5. Do you need help with eating, Physical 1 2
dressing, washing yourself or using
the toilet? Quit Very
Not A
During the past week: SCALE e a muc
at all little
bit h
10. Did you need rest? Fatigue 1 2 3 4
12. Have you felt weak? Fatigue 1 2 3 4
© 2008 TAHITIAN NONI INTERNATIONAL

13. TAHITIAN NONI Juice supports a healthy
cardiovascular system and helps
maintain a healthy heart
Human Clinical Project at BYU-Hawaii 2006
 10 Medically-diagnosed hypertensive subjects
 Drink 2 ounces of TNJ twice a day for 30 days
 Lowers High Blood Pressure
• Pre-treatment Average = 144/83
• Post-treatment Average = 132/76
© 2008 TAHITIAN NONI INTERNATIONAL

14. TAHITIAN NONI Juice supports joint health
TAHITIAN NONI® Juice in Patients with Cervical
Spondylosis
 University of Lagos College of Medicine
 90 subjects (TNJ alone, TNJ+physical therapy, physical
therapy alone)
 15 mL TNJ Juice BID for 4 weeks
 No NSAIDS or analgesics allowed
 Pre and post pain and cervical range of movement
(ROM) measured
© 2008 TAHITIAN NONI INTERNATIONAL

15. © 2008 TAHITIAN NONI INTERNATIONAL

16. Results
Pain intensity decreased significantly from
moderate-severe range to none-moderate
range in all three groups
When TNJ combined with physical
therapy, cervical pain eliminated in almost
all subjects.
© 2008 TAHITIAN NONI INTERNATIONAL

17. Extension Flexion
Rotation Lateral Flexion
© 2008 TAHITIAN NONI INTERNATIONAL

18. Range of Movement
Degrees of TNJ TNJ+PT PT
movement (Before-After) (Before-After) (Before-After)
Flexion 19.9 36.7 20.4 46.9 20.7 40.1
Extension 20.1 36.6 18.8 47.7 19.1 41.5
Lateral 18.0 35.0 17.7 42.5 17.9 38.1
Flexion
Rotation 19.4 40.6 20.0 50.5 20.2 42.5
© 2008 TAHITIAN NONI INTERNATIONAL