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EMBRYOLOGY
INTRODUCTION
Dr. Hina Khan
Assistant Professor
Anatomy
Objectives
Definition of Developmental
Anatomy
Brief history of Developmental
Anatomy
Nomenclatures in
developmental Anatomy
Embryology in the Middle Ages
Holy Quran (seventh century AD), mentions that
human beings are produced from a mixture of
secretions from the male and female. Several
references are made to the creation of a human
being from a nutfa (small drop). It also states that
the resulting organism settles in the womb like a
seed, 6 days after its beginning.
Ancient Views of Human Embryology
 Egyptians approximately 3000 B. C., knew of methods for
incubating birds' eggs, but did not produce record.
 Sanskrit treatise Hindi holy book also describes ancient
ideas concerning the embryo.
 Greek scholars made many important contributions to the
science of embryology.
 The first recorded embryologic studies are in the books of
Hippocrates of Cos, the famous Greek physician (circa
460-377 B. C.), who is regarded as the Father of Medicine.
He explained the developed of embryo.
Terms
Developmental Embryo
It is the field of embryology
concerned with the changes that
cells, tissues, organs, and the body as a
whole undergo from a germ cell of
each parent to the resulting adult.
Trait
Any genetically determined
characteristics is called trait
HOMOZYGOTE
Relating to a cell that has two identical
alleles for a particular trait at
corresponding positions on homologous
chromosomes.
Heterozygote
An individual having different alleles at a
given locus on the homologous
chromosomes is called heterozygote
Dominant Triat
A trait expressed in the homozygous as
well as in the heterozygous
Recessive triat
A trait expressed only in the heterozygote
Genotype
The genetic constitution of an organisum
Phenotype
The observable characteristics of an
individual
Gene Expression
A process by which the information
contained in the gene is converted to
molecules that determine the properties
of cells.
Replication
Production of exact copy of strand of
DNA or (RNA)
Transcription
In which the Single strand of RNA is
synthesized from double strand of DNA
Translation
The conversion of genetic information
contained in RNA in to (protein)
polypeptide chain
In Vivo – In Vitro
In Vitro: any
sequence of
events occur
outside the body
In Vivo: any sequence
of events occur inside
the body
Oocyte (L. ovum, egg)
The female germ or sex
cells are produced in
the ovaries. When
mature, the oocytes are
called secondary
oocytes or mature
oocytes.
Ovaries
Paired female internal
Reproductive organs,
present near the
Uterus
Uterus
Female Internal
Reproductive
organ, divided into:
 Fallopian Tubes
 Body of Uterus
 Cervix
Fallopian Tubes
 They are tube like
structures, lying near
to the ovaries, help in
the transport of ovum,
Fallopian tube divided
into four parts
 This tube is also site
for the fertilization of
Ovum by male gametes
the “sperms”
Male Gametes
Male Gametes are
called as sperms,
they are produced
in the seminiferous
tubules of testis
Testes
 Paired male internal
genitilia present in the
scrotum outside the body
 Containing seminiferous
tubules which provide the
male gametes
Fertilization
Male gametes produced by
the Seminiferous tubules
of testis, deposited into
female genital tract and
only one penetrate the
ovum in the ampulla of
fallopian tube to form the
Zygote
Zygote.
This cell results from
the union of an oocyte
and a sperm during
fertilization. A zygote
or embryo is the
beginning of a new
human being.
Embryo (Gr. embryon)
 The developing human during its
early stages of development.
 The embryonic period extends to
the end of the eighth week (56
days), by which time the
beginnings of all major
structures are present.
Size of Embryo
The size of embryos is
given as crown-rump
length, which is measured
from the vertex of the
cranium (crown of head) to
the rump (buttocks).
Fetus (L., unborn offspring)
 From 9th week to 40th week of
gestational age or 11th week to
38th week after fertilization the
developing baby is called as the
fetus.
 During the fetal period (ninth
week to birth), differentiation and
growth of the tissues and organs
formed during the embryonic
period occur.
Conceptus
 Conceptus (L. conceptio,
derivatives of zygote). The
embryo and its adnexa (L.,
appendages or adjunct
parts) or associated
membranes (i.e., the
products of conception).
 The conceptus includes all
structures that develop
from the zygote, both
embryonic and
extraembryonic.
Implantation
The process during which the
blastocyst attaches to the
endometrium, the mucous
membrane or lining of uterus,
and subsequently embeds in it.
The preimplantation period of
embryonic development is the
time between fertilization and
the beginning of implantation, a
period of approximately 6 days.
Age of Developing Baby
Gestational Age: the age of
baby from the first day of
last menstrual cycle to the
birth of bay. It is about 40
weeks or 10 lunar months or
380 days.
Fertilization Age: age of
baby after the fertilization up
to birth of baby. It is 38
weeks or 366 days. It is two
week shorter than the
gestational age.
Trimester
 The entire pregnancy
divided into three
trimesters, each trimester
consists of three moths.
 The first trimester is very
important in which most of
organs of embryo
developed.
 In second and third
trimester of pregnancy the
differentiation and
morphogenesis of already
formed organs will occur
Postnatal Period
The period
occurring after
birth. Explanations
of frequently used
developmental
terms and periods
follow.
Abortion (L. aboriri, to miscarry)
 A premature stoppage of
development and expulsion of a
conceptus from the uterus or
expulsion of an embryo or fetus
before it is viable-capable of living
outside the uterus.
 Abortion occurs before the fetus
becomes viable that is before the six
months of development
Premature
 Birth of baby, usually
after six months.
 Baby can survive by
keeping in an incubator
by providing the
artificial respiration
 The survival rates
depends upon the age
of fetus
Parturition
 It is the process
of birth of baby
through the birth
canal of woman
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embriology of human

  • 2. Objectives Definition of Developmental Anatomy Brief history of Developmental Anatomy Nomenclatures in developmental Anatomy
  • 3. Embryology in the Middle Ages Holy Quran (seventh century AD), mentions that human beings are produced from a mixture of secretions from the male and female. Several references are made to the creation of a human being from a nutfa (small drop). It also states that the resulting organism settles in the womb like a seed, 6 days after its beginning.
  • 4. Ancient Views of Human Embryology  Egyptians approximately 3000 B. C., knew of methods for incubating birds' eggs, but did not produce record.  Sanskrit treatise Hindi holy book also describes ancient ideas concerning the embryo.  Greek scholars made many important contributions to the science of embryology.  The first recorded embryologic studies are in the books of Hippocrates of Cos, the famous Greek physician (circa 460-377 B. C.), who is regarded as the Father of Medicine. He explained the developed of embryo.
  • 6. Developmental Embryo It is the field of embryology concerned with the changes that cells, tissues, organs, and the body as a whole undergo from a germ cell of each parent to the resulting adult.
  • 8. HOMOZYGOTE Relating to a cell that has two identical alleles for a particular trait at corresponding positions on homologous chromosomes.
  • 9. Heterozygote An individual having different alleles at a given locus on the homologous chromosomes is called heterozygote
  • 10. Dominant Triat A trait expressed in the homozygous as well as in the heterozygous
  • 11. Recessive triat A trait expressed only in the heterozygote
  • 14. Gene Expression A process by which the information contained in the gene is converted to molecules that determine the properties of cells.
  • 15. Replication Production of exact copy of strand of DNA or (RNA)
  • 16. Transcription In which the Single strand of RNA is synthesized from double strand of DNA
  • 17. Translation The conversion of genetic information contained in RNA in to (protein) polypeptide chain
  • 18. In Vivo – In Vitro In Vitro: any sequence of events occur outside the body In Vivo: any sequence of events occur inside the body
  • 19. Oocyte (L. ovum, egg) The female germ or sex cells are produced in the ovaries. When mature, the oocytes are called secondary oocytes or mature oocytes.
  • 20. Ovaries Paired female internal Reproductive organs, present near the Uterus
  • 21. Uterus Female Internal Reproductive organ, divided into:  Fallopian Tubes  Body of Uterus  Cervix
  • 22. Fallopian Tubes  They are tube like structures, lying near to the ovaries, help in the transport of ovum, Fallopian tube divided into four parts  This tube is also site for the fertilization of Ovum by male gametes the “sperms”
  • 23. Male Gametes Male Gametes are called as sperms, they are produced in the seminiferous tubules of testis
  • 24. Testes  Paired male internal genitilia present in the scrotum outside the body  Containing seminiferous tubules which provide the male gametes
  • 25. Fertilization Male gametes produced by the Seminiferous tubules of testis, deposited into female genital tract and only one penetrate the ovum in the ampulla of fallopian tube to form the Zygote
  • 26. Zygote. This cell results from the union of an oocyte and a sperm during fertilization. A zygote or embryo is the beginning of a new human being.
  • 27. Embryo (Gr. embryon)  The developing human during its early stages of development.  The embryonic period extends to the end of the eighth week (56 days), by which time the beginnings of all major structures are present.
  • 28. Size of Embryo The size of embryos is given as crown-rump length, which is measured from the vertex of the cranium (crown of head) to the rump (buttocks).
  • 29. Fetus (L., unborn offspring)  From 9th week to 40th week of gestational age or 11th week to 38th week after fertilization the developing baby is called as the fetus.  During the fetal period (ninth week to birth), differentiation and growth of the tissues and organs formed during the embryonic period occur.
  • 30. Conceptus  Conceptus (L. conceptio, derivatives of zygote). The embryo and its adnexa (L., appendages or adjunct parts) or associated membranes (i.e., the products of conception).  The conceptus includes all structures that develop from the zygote, both embryonic and extraembryonic.
  • 31. Implantation The process during which the blastocyst attaches to the endometrium, the mucous membrane or lining of uterus, and subsequently embeds in it. The preimplantation period of embryonic development is the time between fertilization and the beginning of implantation, a period of approximately 6 days.
  • 32. Age of Developing Baby Gestational Age: the age of baby from the first day of last menstrual cycle to the birth of bay. It is about 40 weeks or 10 lunar months or 380 days. Fertilization Age: age of baby after the fertilization up to birth of baby. It is 38 weeks or 366 days. It is two week shorter than the gestational age.
  • 33. Trimester  The entire pregnancy divided into three trimesters, each trimester consists of three moths.  The first trimester is very important in which most of organs of embryo developed.  In second and third trimester of pregnancy the differentiation and morphogenesis of already formed organs will occur
  • 34. Postnatal Period The period occurring after birth. Explanations of frequently used developmental terms and periods follow.
  • 35. Abortion (L. aboriri, to miscarry)  A premature stoppage of development and expulsion of a conceptus from the uterus or expulsion of an embryo or fetus before it is viable-capable of living outside the uterus.  Abortion occurs before the fetus becomes viable that is before the six months of development
  • 36. Premature  Birth of baby, usually after six months.  Baby can survive by keeping in an incubator by providing the artificial respiration  The survival rates depends upon the age of fetus
  • 37. Parturition  It is the process of birth of baby through the birth canal of woman