Sequence of events in cough. - There is an initial deep inspiration - Then the glottis and vocal cord closes - The diaphragm relaxes - The abdominal muscles and intercostal muscles contract - The pressure within the lungs builds up – up to 100mm of Hg - The glottis and vocal cords open resulting in a rapid release of air under pressure – speeds of upto 100 miles/hour - The sound produced is due to the turbulent flow - It helps to remove any irritant substances from the respiratory system
Other paraneoplastic syndrome: gynaecomastia: in adenocarcinoma Neuro: cerebellar syndrome/poly or dermatomyositis/Lambert-Eaton Myasthenic syndrome (LEMS):Ab directed to Calcium channel in presynaptic membrane NMJ disorder Others: HPOA/clubbing