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Management of
Traumatic Brain Injury
Nakornchai Phuenpathom M.D.
Department of Surgery
Faculty of Medicine
Prince of Songkla University
Definition
• A patient was classified as one with a head
injury if he had one or more of the following
features:
• Definite history of a blow to the head
• Laceration of the scalp or forehead
• Altered consciousness after a relevant
injury, no matter how brief
Scottish Head Injury Management Study. Head injuries in Scottish Hospitals. Lancet 1977; 2: 696-698.
What is TBI?
A blow or jolt to the head that disrupts
	 -	the function of the brain
- a person’s life
	 -	the lives of their families/caregivers.
Traumatic Brain Injury
(TBI)
• An alteration in brain function manifest as:
– Confusion
– Altered level of consciousness
– Seizure
– Coma
– Focal sensory or motor neurological deficit
• Resulting from blunt or penetrating force to
the head
Bruns J, Hauser WA. The epidemiology of traumatic brain injury: A review.
Epilepsia 2003; 44(Suppl. 10): 2-10.
Primary Survey
• A: airway maintenance with cervical spine
protection
• B: breathing and ventilation
• C: circulation with haemorrhage control
• D: disability or neurologic status
• E: exposure / environmental control
D: Disability
• Glasgow Coma Scale (GCS) score: Conscious
level
• Pupillary size and reaction
• Lateralizing signs: motor weakness
• Spinal cord injury level
Glasgow Coma Scale
■ Input
• Command or pain
■ Output
• Best motor response
• Best verbal response
• Eye opening
■ Score range
• 3-15
Decreased Conscious Level
• Decreased cerebral oxygenation and / or
perfusion
• Direct cerebral injury
• Hypoglycemia
• Intoxications from alcohol, narcotics, and other
drugs.
Definition of Severe
Traumatic Brain Injury
■ The patient had a Glasgow coma scale (GCS)
score of 8 or less following nonsurgical
resuscitation or a GCS score deteriorating to 8
or less within 48 hours after head trauma.
■ Nonsurgical resuscitation means endotracheal
intubation, mannitol administration, and volume
support.
Secondary Insults & Injury
• Secondary insults
• detrimental events
• Increased damage to the primary injury
• Hypoxia and hypotension
• Secondary injuries
• processes that develop in the hours to days after the
unavoidable primary injury
• Result of the biochemical cascades initiated by trauma
Mild Traumatic Brain
Injury
Definition ?
• An acute brain injury resulting from mechanical
energy to the head from external physical forces.
Criteria for identification include:*
– One or more of the following	
  
• Confusion or disorientation	
  
• Loss of consciousness for 30 minutes or less	
  
• Post-traumatic amnesia for less than 24 hours	
  
• And/ or other transient neurological abnormalities	
  
– GCS score of 13-15 after 30 minutes post-injury.	
  
– Not be due to drugs, alcohol, medications, caused by
other injuries or treatment for other injuries, caused by
other problems, or caused by penetrating injury.
*MTBI Committee of the Head Injury Interdisciplinary Special Interest Group of the American Congress of Rehabilitation
Medicine1993.
Intracranial Complications
GCS
score
Prevalence of
CT abnormal
Prevalence of
surgical
intervention
Mortality rate
13 30 % 7.5 % 1.1 %
14 20 % 3.6 % 0.01 %
15 5 – 8 % 0.08 % 0.01 %
Borg J, et al. Diagnostic procedures in MTBI: Result of the WHO Collaborating Centre Task Force on MTBI.
J Rehabil Med 2004; Suppl.43:61-75ใ
Diffuse Brain Injury
Cerebral concussion
Physiological change/
dysfunction
Severe traumatic axonal
Injury.
Anatomical damage.
Injury severity
New	
  Orleans	
  Criteria	
  (NOC)
• Headache	
  
• Vomiting	
  
• An	
  age	
  over	
  60	
  years	
  
• Drug	
  or	
  alcohol	
  intoxication	
  
• Deficits	
  in	
  short-­‐term	
  memory	
  
• Physical	
  evidence	
  of	
  trauma	
  above	
  the	
  clavicles	
  
• Seizure
Haydel	
  MJ,	
  Preston	
  CA,	
  Mills	
  TJ,	
  et	
  al.	
  Indications	
  for	
  computed	
  tomography	
  in	
  patients	
  with	
  	
  
Minor	
  head	
  injury.	
  N	
  Engl	
  J	
  Med	
  2000;	
  343:	
  100-­‐5.
The	
  Canadian	
  CT	
  Head	
  Rule	
  (CCHR)
• High	
  risk	
  (for	
  neurological	
  intervention)	
  
– GCS	
  score	
  <	
  15	
  at	
  2	
  hour	
  after	
  inury	
  
– Suspected	
  open	
  or	
  depressed	
  skull	
  fracture	
  
– Any	
  sign	
  of	
  basal	
  skull	
  fracture	
  (hemotympanum,	
  racoon	
  eyes,	
  CSF	
  otorrhea/
rhinorrhea,	
  Battle’s	
  sign)	
  
– Vomiting	
  ≥	
  2	
  episodes	
  
– Age	
  ≥	
  65	
  years	
  
• Medium	
  risk	
  (for	
  brain	
  injury	
  on	
  CT)	
  
– Amnesia	
  before	
  impact	
  >	
  30	
  min	
  
– Dangerous	
  mechanism
Stiell	
  IG,	
  Wells	
  GA,	
  Vandemheen	
  K,	
  et	
  al.	
  The	
  Canadian	
  CT	
  head	
  rule	
  for	
  patients	
  with	
  minor	
  head	
  injury.	
  Lancet	
  2001;	
  357:	
  1391-­‐96.

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Management of traumatic brain injury

  • 1. Management of Traumatic Brain Injury Nakornchai Phuenpathom M.D. Department of Surgery Faculty of Medicine Prince of Songkla University Definition • A patient was classified as one with a head injury if he had one or more of the following features: • Definite history of a blow to the head • Laceration of the scalp or forehead • Altered consciousness after a relevant injury, no matter how brief Scottish Head Injury Management Study. Head injuries in Scottish Hospitals. Lancet 1977; 2: 696-698. What is TBI? A blow or jolt to the head that disrupts - the function of the brain - a person’s life - the lives of their families/caregivers.
  • 2. Traumatic Brain Injury (TBI) • An alteration in brain function manifest as: – Confusion – Altered level of consciousness – Seizure – Coma – Focal sensory or motor neurological deficit • Resulting from blunt or penetrating force to the head Bruns J, Hauser WA. The epidemiology of traumatic brain injury: A review. Epilepsia 2003; 44(Suppl. 10): 2-10. Primary Survey • A: airway maintenance with cervical spine protection • B: breathing and ventilation • C: circulation with haemorrhage control • D: disability or neurologic status • E: exposure / environmental control
  • 3. D: Disability • Glasgow Coma Scale (GCS) score: Conscious level • Pupillary size and reaction • Lateralizing signs: motor weakness • Spinal cord injury level Glasgow Coma Scale ■ Input • Command or pain ■ Output • Best motor response • Best verbal response • Eye opening ■ Score range • 3-15
  • 4. Decreased Conscious Level • Decreased cerebral oxygenation and / or perfusion • Direct cerebral injury • Hypoglycemia • Intoxications from alcohol, narcotics, and other drugs.
  • 5. Definition of Severe Traumatic Brain Injury ■ The patient had a Glasgow coma scale (GCS) score of 8 or less following nonsurgical resuscitation or a GCS score deteriorating to 8 or less within 48 hours after head trauma. ■ Nonsurgical resuscitation means endotracheal intubation, mannitol administration, and volume support. Secondary Insults & Injury • Secondary insults • detrimental events • Increased damage to the primary injury • Hypoxia and hypotension • Secondary injuries • processes that develop in the hours to days after the unavoidable primary injury • Result of the biochemical cascades initiated by trauma
  • 6.
  • 7. Mild Traumatic Brain Injury Definition ? • An acute brain injury resulting from mechanical energy to the head from external physical forces. Criteria for identification include:* – One or more of the following   • Confusion or disorientation   • Loss of consciousness for 30 minutes or less   • Post-traumatic amnesia for less than 24 hours   • And/ or other transient neurological abnormalities   – GCS score of 13-15 after 30 minutes post-injury.   – Not be due to drugs, alcohol, medications, caused by other injuries or treatment for other injuries, caused by other problems, or caused by penetrating injury. *MTBI Committee of the Head Injury Interdisciplinary Special Interest Group of the American Congress of Rehabilitation Medicine1993. Intracranial Complications GCS score Prevalence of CT abnormal Prevalence of surgical intervention Mortality rate 13 30 % 7.5 % 1.1 % 14 20 % 3.6 % 0.01 % 15 5 – 8 % 0.08 % 0.01 % Borg J, et al. Diagnostic procedures in MTBI: Result of the WHO Collaborating Centre Task Force on MTBI. J Rehabil Med 2004; Suppl.43:61-75ใ
  • 8. Diffuse Brain Injury Cerebral concussion Physiological change/ dysfunction Severe traumatic axonal Injury. Anatomical damage. Injury severity New  Orleans  Criteria  (NOC) • Headache   • Vomiting   • An  age  over  60  years   • Drug  or  alcohol  intoxication   • Deficits  in  short-­‐term  memory   • Physical  evidence  of  trauma  above  the  clavicles   • Seizure Haydel  MJ,  Preston  CA,  Mills  TJ,  et  al.  Indications  for  computed  tomography  in  patients  with     Minor  head  injury.  N  Engl  J  Med  2000;  343:  100-­‐5.
  • 9. The  Canadian  CT  Head  Rule  (CCHR) • High  risk  (for  neurological  intervention)   – GCS  score  <  15  at  2  hour  after  inury   – Suspected  open  or  depressed  skull  fracture   – Any  sign  of  basal  skull  fracture  (hemotympanum,  racoon  eyes,  CSF  otorrhea/ rhinorrhea,  Battle’s  sign)   – Vomiting  ≥  2  episodes   – Age  ≥  65  years   • Medium  risk  (for  brain  injury  on  CT)   – Amnesia  before  impact  >  30  min   – Dangerous  mechanism Stiell  IG,  Wells  GA,  Vandemheen  K,  et  al.  The  Canadian  CT  head  rule  for  patients  with  minor  head  injury.  Lancet  2001;  357:  1391-­‐96.