Pharmacy and therapeutic committee, PTC, Organization of PTC, Functions of PTC, Automatic stop order, Emergency drug list, ADR and safety monitoring, Role of Pharmacy and therapeutic committee

1. Pharmacy and Therapeutic Committee
(PTC)
By
Mr. Krushna Kashinathrao Zambare
HOD, Pharmacology
SBSPM B. Pharmacy College, Ambajogai

2. DEFINITION
 PTC is composed of physicians, pharmacist and
medical staff and is concerned with the regulating the
use of medicines in the hospitals.
Or
 PTC is the group of advisory peoples which are
engaged in matters related use of medicines in
hospitals and also analysis of drugs, dosage forms
and safe use of investigational drugs.

3. ORGANIZATION
 The composition of the PTC is as follows,
 Three Physicians from the medical staff of hospital
 The Pharmacist
 Nursing staff representative
 One Ex-officio member as a representative appointed
from Hospital administration
 One of the Physician is the chairman of committee
 Secretary of committee is Pharmacist

4. COMPOSITION
PTC
Physicians
(Chairman)
Pharmacist
(Secretary)
Nursing staff
representative
(Joint Secretary)

5. COMPOSITION
SUB-COMMITTEES OF THE PTC
 Anti-cancer agents
 Anti-diabetic agents
 Gastrointestinal agents
 Endocrine drugs
 Cardiovascular drugs
 CNS acting drugs
 Anti-infective drugs

6. FUNCTIONS
 The committee has three main roles
1) Advisory
2) Educational
3) ADR and Safety monitoring

7. ADVISORY
 PTC is involved in all the matters related with the use of
medicine in hospital
 PTC assists in preparing the guidelines regarding
evaluation, selection and therapeutic use of medicines in
hospitals
 The committee guides the hospital administration and
medical staff in the matters related with medicines use

8. ADVISORY
 Further the committee also provides the guidelines for
hospital pharmacy related with the dispensing of drugs to
patients
 Policy includes various issues, like who may prescribe or
administer drugs, direction during prescription and
guidance, to assure safe and proper use of high-risk,
high-volume, high-cost, or problem-prone drugs

9. ADVISORY
 Moreover PTC also gives recommendation for stock of drugs in
hospital pharmacy
 PTC also assist in the formulation of broad professional
policies relating to drugs, regarding their selection,
prescribing, procurement, storage, distribution, administration,
safety procedures, monitoring, and use
 Furthermore PTC engaged in making rules and regulations for
administration, monitoring and outcomes of drugs and
diagnostic testing materials
 For patients care PTC also recommends the improvement of the
efficacy and safety of drugs

10. EDUCATIONAL
 PTC recommends or assists in the arrangement of
programs for Pharmacists, Nursing staff, Physicians
and other medical staff, which can help in
improvement of knowledge of medicines and their
use

11. ADR AND SAFETY MONITORING
 PTC establishes proactive subcommittees for
medication safety and drug utilization evaluation
 PTC overlook safe, economic and rational use of
pharmaceuticals across the healthcare facility
 PTC monitors and reports all the ADR related with
the drugs (Pharmacovigilence)

12. SOME OTHER FUNCTIONS OF PTC
 Recommends the protocols concerned with evaluation and approval
of investigational new drugs
 Preparing, monitoring, assisting and implementing drug policy
 Regulation of inventory at hospital Pharmacy
 Monitoring and reporting drug Interactions
 Formulation of Hospital Formulary and addition and deletion of
Drugs
 Prepares emergency medicines list helpful in emergency situation
 Managing, reporting and minimizing medication errors

13. POLICIES OF THE PTC IN INCLUDING DRUGS
INTO FORMULARY
 PTC develops policy and procedure governing
hospital formulary
 PTC maintains and prepares formulary based on
following principles
 Effectiveness
 Safety
 Efficient
 Cost
 Patient centered

14. AUTOMATIC STOP ORDER
 PTC formulates the rules and guidelines for the automatic
stoppage of dangerous drugs administration to patients
 Dangerous drugs includes Narcotic, Sedatives, Hypnotics,
Antibiotics, Anticoagulants
 These dangerous drugs should be automatically discontinued
after 48 hours after prescription
 The Narcotic, Sedatives and hypnotic drugs should be re-
prescribed after 24 hours
 unless and until the drug should be prescribed in specified
doses or may be reordered by the physician

15. AUTOMATIC STOP ORDER
These drugs should be only continued or prescribed if,
 Physician writes the number of doses to be administered
 Physician specifies the time period for administration of
drugs
 Physician may re-prescribes the medicine

16. EMERGENCY DRUG LIST PREPARATION
 In emergency situation it is important to administer the
exact drug to save the patients life, hence PTC prepares
the guidelines to keep the emergency drugs at the bed
side.
 PTC prepares the list of such emergency drugs to be kept
in box at bed side
 PTC gives instructions for keeping emergency drug kit to
Pharmacist and Nursing staff

17. EMERGENCY DRUG KIT
 Atropine
 Aminophylline
 Amyl nitrite Inhalation
 Caffeine
 Digoxin
 Heparin
 Pentobarbital
 Hydrocortisone
 Saline
 Water for injection
 Epinephrine
 Syringes 1, 2, 5 ml
volume
 Needles 18’, 20’, 24’, 26’