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Lecture 11b;
Reproduction and
  Development
Introduction
Not all animals have sexual
reproduction, but most do
Gametes are produced in the gonads-
sperm produced in testes and eggs
produced in ovaries
Zygote- the fertilized egg
Introduction
Many animals have external
fertilization- where each parent deposits
egg and sperm in same place,
fertilization occurs outside the body
Internal fertilization- when sperm is
introduced to female by copulation,
fertilization occurs within the body
Ways of Reproduction
Oviparous- lays eggs, either in water or
land
Ovoviviparous- eggs retained in body
until they hatch- give birth to living
young
Viviparous- produce living young- there
is no membrane bound egg
Human Reproduction
Essentially two groups of parts:
  1. Gonads (testes or ovaries) that
  produce the gametes and the sex
  hormones
  2. Accessory organs that conduct
  gametes and in females house the
  embryo and fetus during development
Male System
Male System
Testes produce sperm, are suspended in
the scrotum
  Sperm production must occur at a
  lower temperature than the body- that
  is why they are located there
Epididymis - a coiled tube just outside
each testis, where sperm mature
Male System
Vas deferens- sperm move into these ducts when they
are mature, wait to move into the ejaculatory duct here
Sperm is mixed with secretions from 3 glands to
produce semen
   1. Seminal vesicles- just below bladder, secrete
   nutrients for the sperm
   2. Prostate gland- alkaline fluid believed to
   increase motility
   3. Bulbourethral gland- lubricating secretions
Male System
After combining with seminal fluids from
various glands in the ejaculatory duct, semen
is expelled from the penis through the urethra
(which carries urine as well as semen)
During ejaculation in the male orgasm, sperm
enter the ejaculatory duct from the vas
deferentia, then muscle contractions from the
urethra and muscle at the base of the penis
eject the semen
Male System
Testes produce sperm
Each sperm has a
flagellum which
allows it to swim
Normal ejaculate
~40 million sperm/
mL
Male System
The hypothalamus controls the production
of the testes by secreting gonadotropic
secreting hormone, which triggers
  1. folicle stimulating hormone-
  promotes spermatogenesis
  2. Leutenizing hormone- controls
  production of testosterone
Male System
Testosterone main sex hormone in males
  1. Essential for normal development
  and function of sex organs
  2. Necessary for maturation of sperm
  3. Initiates and maintains
  development of secondary sex
  characteristics
Female System
Female System
Ovaries contain eggs
Ovum exit the ovaries and are picked up by the
oviducts/ fallopian tubes
Fertilization occurs in the first 1/3 of the
fallopian tube, then cilia and muscle
contractions move fertilized egg to the uterus
The uterus is about the size of a pear when idle.
The narrow end that meets the vagina is the cervix
Female System
Fertilized embryo will imbed itself in the lining
of the uterus, the endometrium
External female sexual organs are collectively
called vulva
   Mons pubis, labia minora and majora, and
   clitoris- homologous to penis
   hymen- thin membrane which covers vaginal
   opening, broken by activities of many sorts
Female System
Females are born with eggs, they do not make
them throughout life as males make sperm
However, development occurs:
   Born with Primary oocytes (2n)
   Some of these will develop into secondary
   oocytes (n)
   These are then released from the ovary
   during ovulation
Female System
Estrogen- one main female sex hormone
  Essential for development and function of
  female sex organs
  Responsible for secondary sex
  characteristics
Progesterone- other main female sex hormone
  Works with estrogen to control different
  parts of the cycle
Female System
Menstrual cycle
   Caused by female sex hormones cycling to cause oocyte
   development and ovulation
   Days 1-5- hormone levels low, menstruation occurs as
   endometrium disintigrates
   Days 6-13- Increased estrogen causes endometrium to
   thicken
   Day 14- ovulation
   Days 15-28- increased progesterone causes endometrium
   to double in size- it is ready to receive embryo
Human Development
Fertilization- when sperm and egg fuse to
form a zygote
Embryonic period- first two months
First, embryo becomes multicellular
Cleavage- lots of cell division without growth
- forms morula
Morula becomes hallow, then called blastocyst
Human Development
Gastrulation- 3rd week- the movement
of cells to establish the three germ layers:
endoderm, mesoderm, and ectoderm
Neurulation- formation of the central
nervous system
  Form notochord from mesoderm
  Form CNS from part of ectoderm
Human Development
At 5 weeks, limb buds appear- this will
develop into limbs
  Sense organs begin to form
6-8 weeks- begins to look very human
  At 8 weeks, is only 1.5 inches long,
  but has all organ systems
Human Development
3-9 months is basically growth
Heartbeat heard around week 10
  Weight increases 600 times
  Length increases as well
Fetus is able to move starting around 3rd
month
Organs also continue to develop and grow
Placenta
The ‘sack’ that the fetus is in- has a fetal side
and a maternal side
Maternal and fetal blood do not mix;
exchange occurs across the placenta
   There are chorionic villi where the exchange
   occurs- lots of capillaries around them
   The umbilical cord goes from the fetus to
   the placenta, is part of the fetal circulation
Birth
Probably initiated by the fetal brain
becoming mature enough- brain then
releases hormones which are used by the
placenta to create three more hormones
  estrogen, oxytoin, prostaglandin
  These three hormones cause the uterus
  to contract
Birth

Birth occurs in three basic stages:
  1. Dilation of cervix, amnion breaks
  (Water breaks)
  2. Birth of baby
  3. Delivery of placenta (afterbirth)

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11b; reproduction

  • 2. Introduction Not all animals have sexual reproduction, but most do Gametes are produced in the gonads- sperm produced in testes and eggs produced in ovaries Zygote- the fertilized egg
  • 3. Introduction Many animals have external fertilization- where each parent deposits egg and sperm in same place, fertilization occurs outside the body Internal fertilization- when sperm is introduced to female by copulation, fertilization occurs within the body
  • 4. Ways of Reproduction Oviparous- lays eggs, either in water or land Ovoviviparous- eggs retained in body until they hatch- give birth to living young Viviparous- produce living young- there is no membrane bound egg
  • 5. Human Reproduction Essentially two groups of parts: 1. Gonads (testes or ovaries) that produce the gametes and the sex hormones 2. Accessory organs that conduct gametes and in females house the embryo and fetus during development
  • 7. Male System Testes produce sperm, are suspended in the scrotum Sperm production must occur at a lower temperature than the body- that is why they are located there Epididymis - a coiled tube just outside each testis, where sperm mature
  • 8. Male System Vas deferens- sperm move into these ducts when they are mature, wait to move into the ejaculatory duct here Sperm is mixed with secretions from 3 glands to produce semen 1. Seminal vesicles- just below bladder, secrete nutrients for the sperm 2. Prostate gland- alkaline fluid believed to increase motility 3. Bulbourethral gland- lubricating secretions
  • 9. Male System After combining with seminal fluids from various glands in the ejaculatory duct, semen is expelled from the penis through the urethra (which carries urine as well as semen) During ejaculation in the male orgasm, sperm enter the ejaculatory duct from the vas deferentia, then muscle contractions from the urethra and muscle at the base of the penis eject the semen
  • 10. Male System Testes produce sperm Each sperm has a flagellum which allows it to swim Normal ejaculate ~40 million sperm/ mL
  • 11. Male System The hypothalamus controls the production of the testes by secreting gonadotropic secreting hormone, which triggers 1. folicle stimulating hormone- promotes spermatogenesis 2. Leutenizing hormone- controls production of testosterone
  • 12. Male System Testosterone main sex hormone in males 1. Essential for normal development and function of sex organs 2. Necessary for maturation of sperm 3. Initiates and maintains development of secondary sex characteristics
  • 14. Female System Ovaries contain eggs Ovum exit the ovaries and are picked up by the oviducts/ fallopian tubes Fertilization occurs in the first 1/3 of the fallopian tube, then cilia and muscle contractions move fertilized egg to the uterus The uterus is about the size of a pear when idle. The narrow end that meets the vagina is the cervix
  • 15. Female System Fertilized embryo will imbed itself in the lining of the uterus, the endometrium External female sexual organs are collectively called vulva Mons pubis, labia minora and majora, and clitoris- homologous to penis hymen- thin membrane which covers vaginal opening, broken by activities of many sorts
  • 16. Female System Females are born with eggs, they do not make them throughout life as males make sperm However, development occurs: Born with Primary oocytes (2n) Some of these will develop into secondary oocytes (n) These are then released from the ovary during ovulation
  • 17. Female System Estrogen- one main female sex hormone Essential for development and function of female sex organs Responsible for secondary sex characteristics Progesterone- other main female sex hormone Works with estrogen to control different parts of the cycle
  • 18. Female System Menstrual cycle Caused by female sex hormones cycling to cause oocyte development and ovulation Days 1-5- hormone levels low, menstruation occurs as endometrium disintigrates Days 6-13- Increased estrogen causes endometrium to thicken Day 14- ovulation Days 15-28- increased progesterone causes endometrium to double in size- it is ready to receive embryo
  • 19. Human Development Fertilization- when sperm and egg fuse to form a zygote Embryonic period- first two months First, embryo becomes multicellular Cleavage- lots of cell division without growth - forms morula Morula becomes hallow, then called blastocyst
  • 20. Human Development Gastrulation- 3rd week- the movement of cells to establish the three germ layers: endoderm, mesoderm, and ectoderm Neurulation- formation of the central nervous system Form notochord from mesoderm Form CNS from part of ectoderm
  • 21. Human Development At 5 weeks, limb buds appear- this will develop into limbs Sense organs begin to form 6-8 weeks- begins to look very human At 8 weeks, is only 1.5 inches long, but has all organ systems
  • 22. Human Development 3-9 months is basically growth Heartbeat heard around week 10 Weight increases 600 times Length increases as well Fetus is able to move starting around 3rd month Organs also continue to develop and grow
  • 23. Placenta The ‘sack’ that the fetus is in- has a fetal side and a maternal side Maternal and fetal blood do not mix; exchange occurs across the placenta There are chorionic villi where the exchange occurs- lots of capillaries around them The umbilical cord goes from the fetus to the placenta, is part of the fetal circulation
  • 24. Birth Probably initiated by the fetal brain becoming mature enough- brain then releases hormones which are used by the placenta to create three more hormones estrogen, oxytoin, prostaglandin These three hormones cause the uterus to contract
  • 25. Birth Birth occurs in three basic stages: 1. Dilation of cervix, amnion breaks (Water breaks) 2. Birth of baby 3. Delivery of placenta (afterbirth)

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