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MIRROR NEURONS AND AUTISM

walaa khader
HOW


DO WE STUDY THE BRAIN?

fMRI brain scanners let us see which 'brain
areas' are active for different tasks
WHY


DO PSYCHOLOGISTS STUDY AUTISM?

People with autism have a different way of
understanding the world and interacting with
the world



We want to know how & why



So what do we know already?
THE

BRAIN IN AUTISM
The brain stem of a person with autism is shorter
than a normal brain stem
 the structures at the junction of the pons and the
medulla are closer to the structures of the lower
medulla.
 It is as though a band of tissue were missing.
 The brain stem of a person with autism also did
not have the superior olive.
 the facial nucleus is smaller than normal.

PEOPLE
IN:

WITH AUTISM OFTEN HAVE TROUBLE

Communication and Socialization
 Empathy(Understanding and being aware of
the feelings of others.)
 Physical contact.
 Speech.
 They may learn clever ways to compensate
for this
 Some people with autism are exceptionally
good at drawing or maths or music …
 Many are good at seeing things in detail

STUDYING


THE MIRROR SYSTEM IN AUTISM

Mirror neurons are cells that fire during both
the doing and watching of a specific action.
They have been linked to many behaviors
and abilities, from empathy to learning by
imitation, as well as implicated in conditions
such as autism.
IS

A DYSFUNCTIONAL MIRROR

NEURON SYSTEM RESPONSIBLE FOR

THE

SYMPTOMS

OF AUTISM?
WHAT

IS THE BROKEN MIRROR?

The mirror system might be abnormal in autism
because:






children with autism
don’t imitate people
much
some of the functions
of the mirror system
overlap with the
difficulties seen in
autism
language can develop
slowly in children with
autism
there is very little good evidence to support
broken mirror hypothesis

1.GOAL DIRECTED IMITATION










3-6 year olds imitate goals
not means
Revealed by hand errors on
cross-body trials
Good imitation on all other
trials
Do children with ASD show
the same pattern of errors?

Test 26 children with ASD
and 25 typical children
Bekkering, et al, 2000
Gattis et al, 2002
GOAL

DIRECTED IMITATION

4
asd

hand errors

typically developing
2

0
same
side

cross
body

both
sides

• Both groups replicate Bekkering et al
• No problems with goals in children with ASD
CONCLUSIONS






FROM STUDY

1

Children with autism can imitate goals when
explicitly asked to do so
This suggests they do NOT have a broken mirror
system
This means that children with autism can learn
through imitation, but we need to explicitly ask
them to imitate us
2.RAMACHANDRAN

AND
EXPERIMENT

OBERMAN

they used electroencephalography (EEG) to test
children’s brainwaves while doing and watch
actions.
 Results:
For most children, the same brainwaves were
detected whether they were doing or watch a
specific action. However, for children with ASD,
brainwaves were only detected when they were
doing an action and not detected when they were
watching someone else do the same action, or
even when they were imitating another’s action
This finding supports the "broken mirror
hypothesis" and clearly depicts the relationship
between mirror neurons and the poor social skills
observed in children with ASD (Ramachandran &
Oberman, 2006).
 Since mirror neurons systems are responsible for
humans’ ability to understand and mimic other
peoples’ behavior, the lack of this skill within
persons with ASD can be refer to an impaired
mirror neuron system.

2. The "Broken Mirror Hypothesis" claims that
persons with ASD have impairments to their
mirror neuron system (Press, Richardson &
Bird, 2010)
3. The dysfunction of the mirror neuron
system is a main cause of the poor social
skills in persons with Autism (Marsh &
Hamilton, 2011).
4.some studies actually show that some
individuals with ASD have functioning mirror
neurons systems (Fan Decety, Yang, Liu, &
Yawei, 2010) and believe that there is still
much to learn about the "broken mirror
hypothesis".
MIRROR NEURON SYSTEM IN AUTISM:
BROKEN OR JUST SLOWLY DEVELOPING?
a new study published inBiological
Psychiatry reports that the mirror system in
individuals with autism is not actually broken, but
simply delayed.
 Dr. Christian Keysers, lead author on the project,
detailed their findings, "While most of us have
their strongest mirror activity while they are
young, autistic individuals seem to have a weak
mirror system in their youth, but their mirror
activity increases with age, is normal by about age
30 and unusually high thereafter."

THIS

GRAPH SHOWS THE RELATIONSHIP

BETWEEN AGE AND MIRROR ACTIVITY FOR A
NORMAL BRAIN AND ONE WITH AUTISM.

(CREDIT: IMAGE COURTESY OF ELSEVIER)
Ramachandran, V.S., & Oberman, L., M. (2006).
Broken mirrors: A theory of Autism. Scientific
American, 17, 20-29.
doi:10.1038/scientificamerican0607-20sp
 Press, C., Richardson, D., & Bird, G. (2010).
Intact imitation of emotional facial actions in
autism spectrum conditions. Neuropsychologia,
48, 3291–3297. doi:10.1016/j.neuropsychologia.
2010.07.012
 Marsh, L.E., & Hamilton, C. (2011). Dissociation
of mirroring and mentalising systems in autism.
Neuroimage, 56, 1511-1519.
doi:10.1016/j.neuroimage.2011.02.003

Fan, Y.T., Decety, J., Yang, C.Y., Liu, J.L., & Yawei,
C. (2010). Unbroken mirror neurons in autism
spectrum disorders. Journal of Child Psychology
and Psychiatry. 51(9), 981-988.
 Dr. Christian Keysers .May 5, 2011 . Biological
Psychiatry
 www.AutismResearchNottingham.org


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Mirror Neuron and Autism Brain Development

  • 1. MIRROR NEURONS AND AUTISM walaa khader
  • 2. HOW  DO WE STUDY THE BRAIN? fMRI brain scanners let us see which 'brain areas' are active for different tasks
  • 3. WHY  DO PSYCHOLOGISTS STUDY AUTISM? People with autism have a different way of understanding the world and interacting with the world  We want to know how & why  So what do we know already?
  • 5. The brain stem of a person with autism is shorter than a normal brain stem  the structures at the junction of the pons and the medulla are closer to the structures of the lower medulla.  It is as though a band of tissue were missing.  The brain stem of a person with autism also did not have the superior olive.  the facial nucleus is smaller than normal. 
  • 6. PEOPLE IN: WITH AUTISM OFTEN HAVE TROUBLE Communication and Socialization  Empathy(Understanding and being aware of the feelings of others.)  Physical contact.  Speech.  They may learn clever ways to compensate for this  Some people with autism are exceptionally good at drawing or maths or music …  Many are good at seeing things in detail 
  • 7. STUDYING  THE MIRROR SYSTEM IN AUTISM Mirror neurons are cells that fire during both the doing and watching of a specific action. They have been linked to many behaviors and abilities, from empathy to learning by imitation, as well as implicated in conditions such as autism.
  • 8. IS A DYSFUNCTIONAL MIRROR NEURON SYSTEM RESPONSIBLE FOR THE SYMPTOMS OF AUTISM?
  • 9. WHAT IS THE BROKEN MIRROR? The mirror system might be abnormal in autism because:    children with autism don’t imitate people much some of the functions of the mirror system overlap with the difficulties seen in autism language can develop slowly in children with autism
  • 10. there is very little good evidence to support broken mirror hypothesis 1.GOAL DIRECTED IMITATION      3-6 year olds imitate goals not means Revealed by hand errors on cross-body trials Good imitation on all other trials Do children with ASD show the same pattern of errors? Test 26 children with ASD and 25 typical children Bekkering, et al, 2000 Gattis et al, 2002
  • 11. GOAL DIRECTED IMITATION 4 asd hand errors typically developing 2 0 same side cross body both sides • Both groups replicate Bekkering et al • No problems with goals in children with ASD
  • 12. CONCLUSIONS    FROM STUDY 1 Children with autism can imitate goals when explicitly asked to do so This suggests they do NOT have a broken mirror system This means that children with autism can learn through imitation, but we need to explicitly ask them to imitate us
  • 13. 2.RAMACHANDRAN AND EXPERIMENT OBERMAN they used electroencephalography (EEG) to test children’s brainwaves while doing and watch actions.  Results: For most children, the same brainwaves were detected whether they were doing or watch a specific action. However, for children with ASD, brainwaves were only detected when they were doing an action and not detected when they were watching someone else do the same action, or even when they were imitating another’s action
  • 14. This finding supports the "broken mirror hypothesis" and clearly depicts the relationship between mirror neurons and the poor social skills observed in children with ASD (Ramachandran & Oberman, 2006).  Since mirror neurons systems are responsible for humans’ ability to understand and mimic other peoples’ behavior, the lack of this skill within persons with ASD can be refer to an impaired mirror neuron system. 
  • 15. 2. The "Broken Mirror Hypothesis" claims that persons with ASD have impairments to their mirror neuron system (Press, Richardson & Bird, 2010) 3. The dysfunction of the mirror neuron system is a main cause of the poor social skills in persons with Autism (Marsh & Hamilton, 2011). 4.some studies actually show that some individuals with ASD have functioning mirror neurons systems (Fan Decety, Yang, Liu, & Yawei, 2010) and believe that there is still much to learn about the "broken mirror hypothesis".
  • 16. MIRROR NEURON SYSTEM IN AUTISM: BROKEN OR JUST SLOWLY DEVELOPING? a new study published inBiological Psychiatry reports that the mirror system in individuals with autism is not actually broken, but simply delayed.  Dr. Christian Keysers, lead author on the project, detailed their findings, "While most of us have their strongest mirror activity while they are young, autistic individuals seem to have a weak mirror system in their youth, but their mirror activity increases with age, is normal by about age 30 and unusually high thereafter." 
  • 17. THIS GRAPH SHOWS THE RELATIONSHIP BETWEEN AGE AND MIRROR ACTIVITY FOR A NORMAL BRAIN AND ONE WITH AUTISM. (CREDIT: IMAGE COURTESY OF ELSEVIER)
  • 18. Ramachandran, V.S., & Oberman, L., M. (2006). Broken mirrors: A theory of Autism. Scientific American, 17, 20-29. doi:10.1038/scientificamerican0607-20sp  Press, C., Richardson, D., & Bird, G. (2010). Intact imitation of emotional facial actions in autism spectrum conditions. Neuropsychologia, 48, 3291–3297. doi:10.1016/j.neuropsychologia. 2010.07.012  Marsh, L.E., & Hamilton, C. (2011). Dissociation of mirroring and mentalising systems in autism. Neuroimage, 56, 1511-1519. doi:10.1016/j.neuroimage.2011.02.003 
  • 19. Fan, Y.T., Decety, J., Yang, C.Y., Liu, J.L., & Yawei, C. (2010). Unbroken mirror neurons in autism spectrum disorders. Journal of Child Psychology and Psychiatry. 51(9), 981-988.  Dr. Christian Keysers .May 5, 2011 . Biological Psychiatry  www.AutismResearchNottingham.org 