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Presentation Uvp 16

  1. 1. UV BLOCK GEL (
  2. 2. (UV BLOCK GEL) Active Type of UV Maximum Use in ingredient radiation Concentrati This sun blocked on blocked Ethylhexyl- UV-B 7.5% (US), 5.00% p- 10% (TH, methoxyci EC, AUS) nnamate Butyl UV-A % (US), 5.00% methoxydi % (TH, benzoyl EC,AUS) methane Oxybenzon UV-A,-UV-B 6% baicalensis 2.00% Scutellaria (US), root
  3. 3. The depth of penetration of the skin by UV radiation of different wavelengths: UVB mainly affects the epidermis, while UVA penetrates deeper into the dermis.
  4. 4. Penetration of UV radiation into skin
  5. 5. (Metal Halide Lamp)
  6. 6. (Chemical Sunscreen) - Ethylhexyl-p- methoxycinnamate - Butyl methoxydibenzoyl methane - Oxybenzone
  7. 7. (Chemical Sunscreen)
  8. 8. Ethylhexyl-p-methoxycinnamate  Ethylhexyl-p- methoxycinnamate SPF Solvent  Wavelengths Covered : - nm.
  9. 9. Butyl Methoxydibenzoylmethane Butyl Methoxydibenzoylmet hane Avobenzone Chemical UVA Wavelengths Covered : - nm
  10. 10. Oxybenzone  Benzophenone- Oxybenzone  Skin Cancer Foundation Oxybenzone Stabilizer Avobenzone Neutrogena Helioplex Avobenzone Oxybenzone Oxybenzone Degrade
  11. 11. Scutellaria Bai calensis Root Extract
  12. 12. Benefits 1. Anti inflammations 2. Help leukocyte migration and activation 3. Help free radical scavenging 4. The prevention of lipid peroxidation 5. Depigment Agent
  13. 13. Physiology of Inflammation S.baicalensis flavonoids are effective at the level of enzymes in arachidonic acid metabolism,as well as in leukocyte migration and activation, free radical scavenging, and the prevention of lipid peroxidation. Anti-inflammatory Mechanisms of Scutellaria A major inflammation-modulating action of S. baicalensis GEORGI is via its effects on lipoxygenase in arachidonic acid metabolism. Arachidonic acid, which is esterified in membrane phospholipids,is released in the initial stages of inflammation,generally in response to mediators from activated platelets.Platelets themselves are activated by contact with substances relating to the initial injury such as collagen, thrombin,and bradykinin.
  14. 14. Depigment Agent • Inhibitory effects on L-DOPA oxidizing diphenolase activity of tyrosinase. • Chelation with copper ion. • Inhibition of melanin biosynthesis in cells by their potent antioxidant activities.
  15. 15. Among the tested hydroxyflavones -
  16. 16. Results suggested that the mechanism o f inhibition by could be due to its chelation with copper ion i
  17. 17. Results indicate that the , , -trihydro xyflavones may contribute to the inhibition of melanin biosynthesis i
  18. 18. Conclusion Scutellaria baicalensis is high in active flavonoids. 1.Anti – Inflammatory 2.Depigment Agent * Inhibitory effects on L-DOPA ox idizing diphenolase activity of tyrosinase. Chelation with copper ion. Inhibition of melanin biosynthe sis in cells by their potent antioxi dant activities.
  19. 19. Summary Properties of the UV BLOCK GEL 1. Scutellaria baicalensis