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Muscular
      Physiology
 Jeopardy
 Game Show
1      2      3      4
$100   $100   $100   $100

$200   $200   $200   $200
$300   $300   $300   $300

$400   $400   $400   $400

$500   $500   $500   $500
1      $100a
 T-tubules: transverse tubules that extend across the
  sarcoplasm at right angles to the long axis of the muscle
  fiber. They are formed by inward extensions of the
  sarcolemma. The membrane of the t tubules has ion pumps
  that continually transport Ca++ ions inward from the
  sarcoplasm. They allow electrical impulses traveling along
  the sarcolemma to move deeper into the cell.
 Triad: triplet of tubules; a T tubule sandwiched between two
  sacs of sarcoplasmic reticulum. It allows electrical impulse
  traveling along a T tubule to stimulate the membranes of
  adjacent sacs of the sarcoplasmic reticulum.
1      $100b
 What structures are unique to skeletal muscle fibers?
1      $200a
 Contractility: The impulse travels across the sarcolemma and
  through the t tubules that realease calcium ion into the
  sarcoplasm. The calcium ions bind to troponin molecules and
  initiate a chemical reaction that produces a contraction. The
  process of a muscle contracting is called the sliding filament
  theory.
 Excitability: When a skeletal fiber is stimulated by a signal
  from a motor neuron, the motor neurons connect to the
  sarcolemma. A neuromuscular junction is formed.
  Acetylcholine is released and stimulates acetylcholine
  receptors that initiate an electrical impulse in the
  sarcolemma. This is called excitation.
1        $200b
    Which of the structures involved primarily in contractility
    and which are in invloved in excitability?
1      $300a
 Myofilaments are made up of myosin, actin, tropomyosin,
  and troponin. The myosin heads on the thick myosin form
  cross bridges with the nearby thin actin that contain
  tropomyosin and troponin .
1       $300b
 how the structure of the myofilaments is related to their
  function
1       $400a
 1.     When you exercise and isolate a muscle group, lactic
  acid, produced naturally by your body, begins to build around
  that muscle. That lactic acid accumulates around the
  muscle, resulting in a burning sensation. While the burn is
  often associated with becoming stronger, the feeling of heat
  and fatigue often ends your workout. After a certain number
  of repetitions, the lactic acid causes muscle fatigue as it
  interacts in the calcium in your body. This is evidenced by the
  inability to complete any more repetitions
1     $400b
 WHAT IS LACTIC ACID
1      $500a
 1.    People who exercise seriously are sometimes told to
  work a muscle until they "feel the burn". In terms of how
  muscle is able to release energy, explain what is going on in
  the muscle early in the exercise and when the muscle is
  "burning."
1    $500b
 WHAT CAUSES THE “BURN” YOU FEEL WHEN A MUSCLE
  IS BEING EXERCISED?
2      $100a
A single motor neuron and the muscle fibers connected to it act
                          as a unit
2    $100b
 A MOTOR NEURON AND THE MUSCLE FIBERS
  CONNECTED TO IT IS CALLED WHAT?
2      $200a
 The number of muscle fibers in each motor unit varies in
  different parts of the body. Muscle fibers involved in fine
  motor skills contain a small number of muscle cells. This
  gives the nervous system the option of making very tiny
  adjustments. Those involved gross motor movements have
  many more fibers for each nerve axon or motor neuron. So
  the axon makes a larger movement because of how many
  cells are affected.
2     $200b
 WHAT IS A MOTOR UNIT?
2      $300a
 Cardiac muscle cells make up the myocardium portion of the
  heart wall.
2       $300b
 What is the meaning of a "unit of combined cells" as it relates
  to cardiac Muscle?
2      $400a
 Measure approximately 10-15 micrometers in diameter and
  50-100 micrometers in length. They have an overlapping
  arrangement of light and dark striations.
2      $400b
 How does the structure arrangement affect its function?
BOUNS

2      $500a
Using fiber types, design a muscle for a marathon runner.
BOUNS


2      $500b
 Type I muscle fibers are classified as slow-twitch, which
  means they develop force slowly and relax at a similar pace
  with a longer “twitch” time in between.
 Don’t utilize much energy from ATP.
 More aerobic than anaerobic.
 Can function for longer periods of time with repetitive
  contractions, because of a readily supply of oxygen.
3       $100a
 Stiffening of the joints and muscles of a body after death
3      $100b
 What is Rigor Mortis
3       $200a
 The muscle contraction process first happens by a motor neuron being
  activated. This produces an action potential that passes outward in a
  ventral root of the spinal cord where it is conveyed to a motor end plate on
  each muscle fiber. The action potential causes the release of packets of
  acetylcholine into the synaptic clefts on the surface of the muscle fiber. The
  acetylcholine causes the electrical resting potential under the motor end
  plate to change, and this then initiates an action potential which passes in
  both directions along the surface of the muscle fiber. At the opening of each
  transverse tubule onto the muscle fiber surface, the action potential
  spreads inside the muscle fiber. At each point where a transverse tubule
  touches part of the sarcoplasmic reticulum, it causes the sarcoplasmic
  reticulum to release Ca+2 ions. The calcium ions result in movement of
  troponin and tropomyosin on their thin filaments, and this enables the
  myosin molecule heads to "grab and swivel" their way along the thin
  filament. This is the driving force of muscle contraction
3      $200b
 What are the 4 factors that influence the strength of muscle
  contractions?
3       $300a
 is a single contraction of skeletal muscle. The three distinct
  phases are latent, contraction, and relaxation.
3      $300b
 What are the phases of a twitch contraction?
3      $400a
 Skeletal muscle moves bones by receiving acetelecholine
  from a motor nerve that triggers an action potential across
  the muscle fibers. Muscle fibers contain actin and
  myosin, which are the function components of muscle
  contraction. essentially, movement of a bone occurs when
  the muscle attached is being shortened
3      $400b
 how does the skeletal muscles provide movement, heat, and
  posture
BOUNS
3       $500a
 Type II fibers are the fast-twitch, explosive muscle fibers
  associated with power and explosiveness in athletes.
 “Inefficient and fatigable”
 They characterize high anaerobic power but very low aerobic
  power which equates to shorter duration, but more powerful
  contractions of the muscle as a whole.
 The main difference between type 2a and type 2b muscle fibers
  comes from their “capacity for aerobic-oxidative energy supply.”
  Type 2a muscle fibers have a more efficient means of aerobic
  metabolism due to a higher number of surrounding capillaries
  that circulate blood throughout the muscle which results in a
  higher resistance to fatigue.
BOUNS

3      $500b
 Using fiber types, design a muscle ffor a 100-yard-dash
  Sprinter.
4       $100a
 Latent Phase: Is the interval from the stimulus application until
  the muscle begins to contract (shorten). Note that there is no
  traced activity during this phase, but there are some electrical
  and chemical changes taking place during this phase.

 Contraction Phase: This phase is when the muscle fibers
  shorten, the tracings will show during this phase (a) peak(s).


 Relaxation Phase: This phase is represented by the downward
  curve in your tracings, this is when the muscle is going back to
  its original state of relaxation and the muscle will once again
  lengthen
4      $100b
 What molecular events occur during each of these phases?
4      $200a
 As you warm-up, you stretch your muscles and create
  microscopic tears in the muscle, making it easier to continue
  with the same exercise.
4      $200b
 How does the treppe effect relate to the warm-up exercises
  of athletes?
4      $300a
 is the explanation for how muscles produce force (or, usually,
  shorten). It explains that the thick and thin filaments within
  the sarcomere slide past one another, shortening the entire
  length of the sarcomere. In order to slide past one another,
  the myosin heads will interact with the actin filaments and,
  using ATP, bend to pull past the actin.
4       $300b
 What is the sliding filament theory?
4       $400a
 are an intracellular signaling molecule for muscle contraction.
  so This enables a contraction, and a return of the calcium in
  the sarcoplasmic reticulum allows the muscle to relax.
4   $400b
what is Calcium ions
4   $500a
WINNER
4   $500b
YOU ARE THE WINNER

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Jeopary

  • 1. Muscular Physiology Jeopardy Game Show
  • 2. 1 2 3 4 $100 $100 $100 $100 $200 $200 $200 $200 $300 $300 $300 $300 $400 $400 $400 $400 $500 $500 $500 $500
  • 3. 1 $100a  T-tubules: transverse tubules that extend across the sarcoplasm at right angles to the long axis of the muscle fiber. They are formed by inward extensions of the sarcolemma. The membrane of the t tubules has ion pumps that continually transport Ca++ ions inward from the sarcoplasm. They allow electrical impulses traveling along the sarcolemma to move deeper into the cell.  Triad: triplet of tubules; a T tubule sandwiched between two sacs of sarcoplasmic reticulum. It allows electrical impulse traveling along a T tubule to stimulate the membranes of adjacent sacs of the sarcoplasmic reticulum.
  • 4. 1 $100b  What structures are unique to skeletal muscle fibers?
  • 5. 1 $200a  Contractility: The impulse travels across the sarcolemma and through the t tubules that realease calcium ion into the sarcoplasm. The calcium ions bind to troponin molecules and initiate a chemical reaction that produces a contraction. The process of a muscle contracting is called the sliding filament theory.  Excitability: When a skeletal fiber is stimulated by a signal from a motor neuron, the motor neurons connect to the sarcolemma. A neuromuscular junction is formed. Acetylcholine is released and stimulates acetylcholine receptors that initiate an electrical impulse in the sarcolemma. This is called excitation.
  • 6. 1 $200b Which of the structures involved primarily in contractility and which are in invloved in excitability?
  • 7. 1 $300a  Myofilaments are made up of myosin, actin, tropomyosin, and troponin. The myosin heads on the thick myosin form cross bridges with the nearby thin actin that contain tropomyosin and troponin .
  • 8. 1 $300b  how the structure of the myofilaments is related to their function
  • 9. 1 $400a  1. When you exercise and isolate a muscle group, lactic acid, produced naturally by your body, begins to build around that muscle. That lactic acid accumulates around the muscle, resulting in a burning sensation. While the burn is often associated with becoming stronger, the feeling of heat and fatigue often ends your workout. After a certain number of repetitions, the lactic acid causes muscle fatigue as it interacts in the calcium in your body. This is evidenced by the inability to complete any more repetitions
  • 10. 1 $400b  WHAT IS LACTIC ACID
  • 11. 1 $500a  1. People who exercise seriously are sometimes told to work a muscle until they "feel the burn". In terms of how muscle is able to release energy, explain what is going on in the muscle early in the exercise and when the muscle is "burning."
  • 12. 1 $500b  WHAT CAUSES THE “BURN” YOU FEEL WHEN A MUSCLE IS BEING EXERCISED?
  • 13. 2 $100a A single motor neuron and the muscle fibers connected to it act as a unit
  • 14. 2 $100b  A MOTOR NEURON AND THE MUSCLE FIBERS CONNECTED TO IT IS CALLED WHAT?
  • 15. 2 $200a  The number of muscle fibers in each motor unit varies in different parts of the body. Muscle fibers involved in fine motor skills contain a small number of muscle cells. This gives the nervous system the option of making very tiny adjustments. Those involved gross motor movements have many more fibers for each nerve axon or motor neuron. So the axon makes a larger movement because of how many cells are affected.
  • 16. 2 $200b  WHAT IS A MOTOR UNIT?
  • 17. 2 $300a  Cardiac muscle cells make up the myocardium portion of the heart wall.
  • 18. 2 $300b  What is the meaning of a "unit of combined cells" as it relates to cardiac Muscle?
  • 19. 2 $400a  Measure approximately 10-15 micrometers in diameter and 50-100 micrometers in length. They have an overlapping arrangement of light and dark striations.
  • 20. 2 $400b  How does the structure arrangement affect its function?
  • 21. BOUNS 2 $500a Using fiber types, design a muscle for a marathon runner.
  • 22. BOUNS 2 $500b  Type I muscle fibers are classified as slow-twitch, which means they develop force slowly and relax at a similar pace with a longer “twitch” time in between.  Don’t utilize much energy from ATP.  More aerobic than anaerobic.  Can function for longer periods of time with repetitive contractions, because of a readily supply of oxygen.
  • 23. 3 $100a  Stiffening of the joints and muscles of a body after death
  • 24. 3 $100b  What is Rigor Mortis
  • 25. 3 $200a  The muscle contraction process first happens by a motor neuron being activated. This produces an action potential that passes outward in a ventral root of the spinal cord where it is conveyed to a motor end plate on each muscle fiber. The action potential causes the release of packets of acetylcholine into the synaptic clefts on the surface of the muscle fiber. The acetylcholine causes the electrical resting potential under the motor end plate to change, and this then initiates an action potential which passes in both directions along the surface of the muscle fiber. At the opening of each transverse tubule onto the muscle fiber surface, the action potential spreads inside the muscle fiber. At each point where a transverse tubule touches part of the sarcoplasmic reticulum, it causes the sarcoplasmic reticulum to release Ca+2 ions. The calcium ions result in movement of troponin and tropomyosin on their thin filaments, and this enables the myosin molecule heads to "grab and swivel" their way along the thin filament. This is the driving force of muscle contraction
  • 26. 3 $200b  What are the 4 factors that influence the strength of muscle contractions?
  • 27. 3 $300a  is a single contraction of skeletal muscle. The three distinct phases are latent, contraction, and relaxation.
  • 28. 3 $300b  What are the phases of a twitch contraction?
  • 29. 3 $400a  Skeletal muscle moves bones by receiving acetelecholine from a motor nerve that triggers an action potential across the muscle fibers. Muscle fibers contain actin and myosin, which are the function components of muscle contraction. essentially, movement of a bone occurs when the muscle attached is being shortened
  • 30. 3 $400b  how does the skeletal muscles provide movement, heat, and posture
  • 31. BOUNS 3 $500a  Type II fibers are the fast-twitch, explosive muscle fibers associated with power and explosiveness in athletes.  “Inefficient and fatigable”  They characterize high anaerobic power but very low aerobic power which equates to shorter duration, but more powerful contractions of the muscle as a whole.  The main difference between type 2a and type 2b muscle fibers comes from their “capacity for aerobic-oxidative energy supply.” Type 2a muscle fibers have a more efficient means of aerobic metabolism due to a higher number of surrounding capillaries that circulate blood throughout the muscle which results in a higher resistance to fatigue.
  • 32. BOUNS 3 $500b  Using fiber types, design a muscle ffor a 100-yard-dash Sprinter.
  • 33. 4 $100a  Latent Phase: Is the interval from the stimulus application until the muscle begins to contract (shorten). Note that there is no traced activity during this phase, but there are some electrical and chemical changes taking place during this phase.  Contraction Phase: This phase is when the muscle fibers shorten, the tracings will show during this phase (a) peak(s).  Relaxation Phase: This phase is represented by the downward curve in your tracings, this is when the muscle is going back to its original state of relaxation and the muscle will once again lengthen
  • 34. 4 $100b  What molecular events occur during each of these phases?
  • 35. 4 $200a  As you warm-up, you stretch your muscles and create microscopic tears in the muscle, making it easier to continue with the same exercise.
  • 36. 4 $200b  How does the treppe effect relate to the warm-up exercises of athletes?
  • 37. 4 $300a  is the explanation for how muscles produce force (or, usually, shorten). It explains that the thick and thin filaments within the sarcomere slide past one another, shortening the entire length of the sarcomere. In order to slide past one another, the myosin heads will interact with the actin filaments and, using ATP, bend to pull past the actin.
  • 38. 4 $300b  What is the sliding filament theory?
  • 39. 4 $400a  are an intracellular signaling molecule for muscle contraction. so This enables a contraction, and a return of the calcium in the sarcoplasmic reticulum allows the muscle to relax.
  • 40. 4 $400b what is Calcium ions
  • 41. 4 $500a WINNER
  • 42. 4 $500b YOU ARE THE WINNER