hafiza madiha jaffar student of M.phil (HND) from government college university Faisalabad

4. ROAD MAP
introduction classification objective
About the
product
Material use
budgeting method
Benefits of
ingredients
Nutrition
summary
Active
ingredients
Health
benefits
Mechanism
of action
Papaya Drug
Interactions
SIDE
EFFECTS
references

5. Classsification
• Kingdom Plantae
• Subkingdom Tracheobionta
• Superdivision Spermatophyta
• Division Magnoliophyta
• Class Magnoliopsida
• Subclass Dilleniidae
• Order Violales
• Family Caricaceae
• Genus Carica
• Species Carica papaya

6. INTRODUCTION
• FAMILY: Caricaceae
SCIENTIFIC NAME: Carica papaya L.
ORIGIN: American tropical lowlands
• Carica papaya, is a powerhouse of nutrients, it contains both
macro and micronutrients and several enzymes.
• Papaya leaves are used to make medicine and leaves extract
having potential Activity of increasing platlets against dengue
fever found in their study. . (Ahmed et al)
• it`s used for preventing and treating gastrointestinal tract
disorders, intestinal parasite infections. It is also used for nerve
pains .

7. Continue…
• The enzymes include papain , chymopapain.
• Possible mechanisms of action include the activity of proteolytic
enzymes, chemopapain and papain, as well as an antimicrobial
activity.papain improved digestion of protein.
• Due to its antioxidant properties, papaya prevents the oxidation
of cholesterol. Also, the high fiber content helps in lowering the
bad cholesterol level. also contains several protein-digesting
enzymes -papain and chymopapain which are responsible to
lower inflammation and improves healing from burns.

8. Nutrition Summary
• 100g of papaya gives
• Total Calories 39kcal
• Protein 0.5 g
• Fat 0.4 g
• Carbohydrate 9.8 g

9. ENERGY 163kJ (39 kcal)
CARBHOHYDRATES 9.81g
SUGARS 5.9 g
DIETARY FIBRE 1.8 g
FAT 0.4 g
VITAMIN A EQUIV. 328 μg (41%)
THIAMINE (VIT.B1) 0.04 mg (3%)
RIBOFLAVIN (VIT.B2) 0.05 mg (4%)
NIACIN (VIT. B3) 0.338 mg (2%)
VITAMIN B6 0.1 mg (8%)
FOLATE(VITB9) 38 μg (10%)
VITAMIN C 61.8 mg (74%)
CALCIUM 24 mg (2%)
IRON 0.10 mg (1%)
PHOSPHOROUS 5 mg (1%)

10. Active ingredients
• Papaya contains a chemical called papain, which is commonly
used as a meat tenderizer.
• Papain breaks down proteins, carbohydrates, and fats. That’s
why it works as a meat tenderizer. However, papain is changed
by digestive juices, so there is some question about whether it
could be effective as a medicine when taken by mouth.
Papaya also contains a chemical called carpain. Carpain seems
to be able to kill certain parasites, and it might affect the
central nervous system.

11. health benefits and uses of papaya
•Diabetes
• lower Blood Pressure
(A.Eno. and R.Konya,2000)
•Asthma prevention
•Reduced risk of certain cancer like prostate cancer
•lower inflammation and improves healing from burns
•lowering the bad cholesterol level.

12. Continue….
• Weight Loss
• Morning Sickness
• Osteoporosis
• Anti-ageing
• Reduced Constipation
• improve Immunity
• Shampoos
• Reduced Kidney disorder
• Intestinal Worms

13. Mechanism of action
• Major digestion problems occur when undigested food reaches
lower intestine. This happens particularly in case of eating large
quantities of meat with fast speed. The natural digestive
enzymes produced in the pancreas and stomach acids generally
can’t meet the digestion requirements under those conditions.
(Tenenhouse, Harriet S. Deutsch, H. F.1966)
• Unlike carbohydrates, which get digested by saliva produced
during chewing, protein do not get digested by saliva. Protein
digestion has a different mechanism. Protein gets digested with
the help of proteolytic enzymes produced in the pancreas.

14. • Papaya helps digesting proteins well because Papain is similar other
types of enzymes made in the pancreas that help our bodies digest meat.
But, these enzymes need acid for activation and papain can work even
without the presence of acid.(Tsai C C, Linn C C)
• digestive benefits of papaya comes from various proteolytic (protein
digesting) enzymes. papain which is very similar to the digestive juice
pepsin. An important characteristic of papain is that it breaks down
proteins.
• It breaks complex bonds of protein down to individual amino
acids which are ready for use for repair and growth of the body
Cont……..

15. OBJECTIVES
To develop a nutraceutical drink for improve protein digestion.
Nutritional profiling of papaya nutraceutical drink
To assess the storage stability of papaya nutraceutical drink

16. ABOUT THE PRODUCT
• Papaya
• Orange
• Almond
• Stevia
This product
contains
• antioxidant nutrients such as
carotenes, vitamin C and
flavonoids, B vitamins, folate
and pantothenic acid, dietary
fiber, vitamin E, vitamin A and
vitamin K. Minerals like
potassium, magnesium are
present in papaya.
Provide vitamins
and minerals
necessary for
daily diet such as

17. BENEFITS OF INGREDENTS
PAPAYA
1) Effective in combating obesity
2) Contains essential vitamins and minerals
1)Prevent cancer
2)good for skin
3)diabetes management
4)prevent formation of kidney stone
ALMOND
1)Regulation of cholesterol
2)Bone Health
3)Good for heart
STEVIA
Natural sweetener which helps to lower blood sugar level.
Contains trace minerals like zinc, chromium

18. MATERIALS USED
Ingredients Amount
Papaya pulp 500g
Stevia ½ tsp (2.5g)
Orange pulp 250g
Almond
Preservative
10-12
………

19. BUDGETING
Ingredients Price
Papaya Rs.
Orange Rs.
Almond Rs.
Stevia Rs.
Preservative Rs.
Packaging material Rs.
Total

20. Method
Make pulp of
fresh papaya
and orange
Grind almond
after removing
peel
Mix the
ingredient as
per standard
Add stevia
and filter in
home and enjoy 

21. Papaya Drug Interactions
Total of 3 drugs (6 brand and generic names) are known to interact
with papaya.
Medications known to interact with papaya
• Anisindione
• Miradon (anisindione)
• Dicumarol
• Coumadin (warfarin)
• Jantoven (warfarin)
• Warfarin (Papaya might increase the effects of warfarin and increase the
chances bleeding)

22. PAPAYA SIDE EFFECTS
• when taken in large amount of papaya cause damage the esophagus.
Irritate skin as papaya latex when apply on skin.
• Unsafe during pregnancy (papain might poison the fetus or cause birth
defects) and breast feeding.(Kadry Mohamed Sadek.2012)
• DiabetesPeople (with diabetes blood sugar as adjustments to medications
might be needed)
• Low blood sugar
• Papain allergy
• Latex allergy
• Surgery (papaya might affect blood sugary during and after surgery. stop 2
weeks before surgery)

23. References
• Ahmed, N., H.Fazal, M. ayaz,B.H.Abbasi, I. Mohammad and
L.fazal.2011.Asian pak J Trop BioMed.1 (4), 330-333.
• Kadry Mohamed Sadek.2012.Antioxidant and immunostimulant
effect of Carica papaya L. aquous extract Acrylamide intoxicated
rats, 20(3), 180-185
• A.Eno. and R.Konya,2000.Blood pressure depression by the fruit
juice of Carica Papaya.
• Tsai C C, Linn C C, Papaiya: Boosting Enzyme, Journal of
Ethnopharmacology, 44 (1996) 56.