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International Journal of Life-Sciences Scientific Research (IJLSSR), VOLUME 1, ISSUE 1, pp: 5-7 SEPTEMBER-2015
http://ijlssr.com IJLSSR © 2015 All rights are reserved
A REVIEW ON MEDICINAL VALUES AND COMMERCIAL UTILITY OF BAEL
Pawan Singh Gurjar, Narayan Lal*, Alok Kumar Gupta and Evening Stone Marboh
Indian Council of Agricultural Research- National Research Centre on Litchi, (Ministry of Agriculture, Govt. of India), Muzaffarpur, Bihar
ABSTRACT- Bael (Aegle marmelos) fruit is one of the blessings from nature for the mankind which is packed with enormous medicinal advantag-
es. Its medicinal properties have been described in the ancient medical treatise in Sanskrit, Charaka Samhita. All parts of this tree from stem, bark,
root; leaves and fruit at all stages of maturity have medicinal value and have been used as medicine for a long time. Many antioxidant compounds
such as flavonoids, flavones, isoflavones, coumarin, anthocyanin, lignans, catechins and isocatechins are found in the fruit pulp (Maity and Hansda,
2009). This plant has tremendous uses listed in Ayurvedic and Unani and Siddha Systems of medicine. This plant is having great potential to cure the
disease like diabetes, cholesterol, peptic ulcer, inflammation, diarrhoea, and dysentery, anticancer, cardio protective, anti bacterial, anti fungal, radio
protective, anti pyretic, analgesic, constipation, respiratory infection, antioxidant, hepatoprotective, wound healing and many more. The present re-
view summarizes the scientific information of various aspects of Aegle marmelos plant used in traditional system of medicine for variety of purpose
and its commercial importance.
Key Words: Bael, Medicine, Antioxidants, Flavonoids, Lignans, Catechins
-------------------------------------------------IJLSSR-----------------------------------------------
INTRODUCTION
Bael, Aegle marmelos, a plant of Indian origin having tremendous thera-
peutic potential and it is belong to family Rutaceae, it is known by the
several other names in the different parts of the country and also outside
of the country (Sharma et al. 2007). In India, the plant is widely culti-
vated particularly in Uttar Pradesh and Bihar. So far around fifteen dis-
tinct cultivars, viz., Basti No. 1, Kagzi Gonda, Gonda No. 1, Gonda No.
2, Gonda No. 3, Kagzi Etawah, Sewan Large, Mirzapuri, Deorya Large,
Chakaiya, Baghel, Lamba, Pant Shivani and Pant Urvashi have been
reported. It is called by different names over different parts of India such
as bilva, bel, sadaphal and shriphal. It is used in the worship of Lord
Shiva from historic times and hence commonly known as tree of Shiva.
Tree is slow-growing and of medium size (12-15 m), generally cultivated
in the vicinity of temple garden. It also vigorously grows in dry forest.
Almost every part of this tree viz. stems, barks, roots, leaves, flowers &
fruits at all stages of maturity have medicinal virtues and have been used
Received: 29 July 2015/Revised: 15 August 2015/Accepted: 29 August 2015
in various Ayurvedic medicines since long time for the treatment of
specific disorders such as respiratory disorders, constipation, ulcer, di-
arrhea, dysentery and many others (Agarwal, 1997). It is also an impor-
tant environmental protector as leaves and bark act as a sink by absorb-
ing dust and foul and poisonous gases from surrounding atmosphere and
makes them clean. Owing to its environment friendly nature, bael is
being placed among plant species group called “climate purifiers” which
emit a greater percentage of oxygen in sunlight as compared to other
plants (Anurag et al., 2004). Due to its endless uses, bael is also known
as Mahaphala or Great fruit (Parichha, 2004).
Nutritional value
Different stdies have shown that bael fruit has significant mineral and
vitamin contents. It also contain moisture 64.2%, protein 1.8%, fat 0.2%,
mineral 1.5%, fibre 2.2%, carbohydrate 31.8%, calcium 0.06%, phos-
phorous 0.05%, potassium 0.6%, vitamin C 0.01%, riboflavin 1.2%,
nicotinic acid 0.9%, thiamin 0.01% and iron 0.3% per 100 gm (Rathore,
2009). Its calorific value is 137 (Panda, 2000).
Medicinal Value
Diarrhoea and dysentery
Generally dried fruit pulp and its powder are used for the treatment of
diarrhoea. The dried powder is also used as an important remedy for
chronic dysentery conditions characterized by alternate diarrhoea and
constipation (Sharma et al., 2007).
Antidiabetic activity
It has been found that bael extract significantly reduces blood urea and
cholesterol level in diabetic animals. It also decreases oxidative stress in
*
Address for Correspondence:
C/O- Narayan Lal Scientist (Horticulture-Fruit Science)
Indian Council of Agricultural Research-National Research Centre
on Litchi (Ministry of Agriculture, Govt. of India)
Muzaffarpur - 842 002, Bihar, India
Mobile: +91-7677456550
Alternate Email ID: narayan@nrclitchi.org.in
Review Article (Open access)
International Journal of Life-sciences Scientific Research (IJLSSR), VOLUME 1, ISSUE 1
http://ijlssr.com IJLSSR © 2015 All rights are reserved
diabetic animal. Leaf juice is directly employed in Unani system of med-
icine for antidiabetic activity (Akhtar et al., 2005).
Cardioprotective activity
The protective effect was estimated by administration of leaf extract in
isoprenaline induced myocardial infarction in experimental animal
(Prience and Rajadurai, 2005).
Anticancer activity
Studies showed that Indian bael extract possess significant antiprolifera-
tive effect. It inhibits in vitro proliferation of human tumor cell lines
including the leukemic K562 and Tlymphoid Jurhat (Lampronti et al.,
2003).
Leucoderma
Psoralen present in the pulp of Aegle marmelos, increases tolerance of
sunlight which aids in the maintenance of normal skin color and thus, it
is employed in the treatment of leucoderma (Gupta et al., 2006).
Eye infections
The leaves of Aegle marmelos are considered an effective treatment for
ophthalmia and various eye inflammations such as conjunctivitis (Shar-
ma et al., 2010).
Constipation
The riped bael fruit act as good laxative. It promotes peristaltic move-
ments and thus helpful in the removal of fecal matter (Roy and Singh,
1980).
Peptic ulcer
Bael fruit and leaf infusion has been used for the treatment of peptic
ulcer. One of the important advantages of this fruit is that it forms a mu-
cilaginous layer on the gastric mucosa and thus prevents interaction of
acid with mucosal layer (Goel et al., 2000).
Antiburn and Radioprotective
Bael fruit powder mixed with mustard oil is used externally for the
treatment of burn. It was found in various studies that due to free sca-
venging activity, bael fruits have radio protective effect (Kruawan and
Kangsadalampai, 2006).
Ear Problems
The root of this tree possesses astringent activity and is used as a home
remedy for curing ear problems. The astringent extract of the roots of
Aegle marmelos combined with the antiseptic properties of neem helps
in curing ear infection, chronic inflammation and pus discharge. The
juice of leaves processed in oil is also used as ear drops to treat ear infec-
tion (Rusia and Srivastav, 1988).
Antifungal and antibacterial
The unsaponifiable matter from the oil obtained from the seeds of Aegle
marmelos was effective as antifungal and antibacterial agent (Benerjee et
al., 1983).
Miscellaneous Properties
Bael tree is a holy tree and it has several medicinal properties, some of
their practical applications are still under evaluation. Apart from the
activity listed above there is little more important activity. The leaves of
Aegle marmelos are useful in the treatment of the jaundice and leucor-
roea, conjunctivitis and defenses. Fruits give energy and nutrition. It is
used in the carminative and astringent and also a good remedy for snake
bite. Application are also reported in anemia, fractures, typhoid, coma,
colitis (Sharma et al., 2007). The methanolic extract of Aegle marmelos
gives the anxiolytic and antidepressant effect (Kothari et al., 2010).
General uses
Wood is used in house building, cart construction, combs and different
household’s articles, leaves as fodder, tooth brushes and chew sticks,
flowers used in cooling drinks, stem gum used for adhesive and book
binding, a yellow dye obtained from rind of unripe fruit is used in print-
ing and whole tree is used as wind barrier.
Processed product
A large number of bael processed products have been prepared. Preserve
and candy are prepared from mature (tender green fruit), fruit squash,
fruit pulp, dehydrated bael, Ready to serve (RTS) drink, bael powder,
jam, slab, toffee and panjiri are other product prepared from bael fruit.
Phytochemicals
It was found that leaves, stem and root of this plant contains significant
amount of tannins, alkaloids, coumarins and steroids. Different phyto-
chemicals are listed in table 1.
Table 1: Phytochemicals present in different parts of Aegle marmelos
Marketed formulation of Aegle marmelos
Some of the marketed formulations of Aegle marmelos produced by
different companies in tablets, capsules, syrups, etc. are listed in table 2.
Plant part Phytochemicals
Leaf Skimmianine, Aeglin, Rutin, γ-sitosterole, β-sitosterol,
Flavone,Lupeol, Cineol, Citral, Glycoside, O-isopentenyl,
Hallordiol, Mameline, Citronellal, Cuuminaldehyde phenyle-
thyle cinnamamides, Euginol, Marmesinin, Aegelin, Glycoside
Fruit Marmelosin, Luvangetin, Aurapten, Psoralen, Marmelide,
Tannin, Phenol
Bark Fagarine, Marmin, Furoquinoline, Alkaloids
Seed Essential oil – D- limonene, A-D-phellandrene, Cineol, Ci-
tronellal, Citral, P-cyrnene, Cumin aldehyde
Root Alkaloid, Halopine, Coumarins, Terpines.
International Journal of Life-sciences Scientific Research (IJLSSR), VOLUME 1, ISSUE 1
http://ijlssr.com IJLSSR © 2015 All rights are reserved
Table 2: Marketed formulation of Aegle marmelos
Marketed formulations Company Name
Chyawanprash Himalaya
Aegle Marmelos Capsules La-Medicca (India) Pvt. Limited
Leucare capsules Shrey Nutraceuticals & Herbals
Entrostat Syrup Ambika Medico
Kof-Rid Syrup Ambika Medico
Pregeight Sydler Remedies Pvt. Ltd.
Ojamin Tates Remedies
Manasamithravatakram Oushadhi
Pushyanugam gulika Oushadhi
Vilwadi gulika Oushadhi
Glucomap Maharishi Ayurveda
Ulco Bliss Tablets Bliss ayurveda
Capsule Bilv Giri Ayurvedic Sanjivani
R-Qunol Syrup Vatsal Ayurvedic Products (P) ltd
REFERENCES
[1] Agarwal VS. Rural economics of medicinal plants: Vegetation in
the forest. In: Drug plants of India. New Delhi, Kalyani Publishers,
1997; pp 6- 44.
[2] Akhtar J, Jamil S, and Azhar MU. Diabetes mellitus: Prevention
and management. Natural Product Radiance, 2005; 4(5): 413-415.
[3] Anurag S, Sharma HK, Pragati K, and Ashutosh U. Bael (Aegle
marmelos Correa) products processing: A review. African Journal
of Food Science, 2014; 8(5): 204–215.
[4] Banerjee AK, Kaul VK, and Nigam SS. Chemical, microbial and
antihelminthic examination of the seeds of Aegle marmelos Correa.
Indian Drugs, 1983; 21(5): 217-218.
[5] Goel RK, Maiti RN, Manickan M, and Ray AB. Antiulcer activity
of naturally occurring ptrano coumarin and isocoumarin and their
effect on prostanoid synthesis using human colonic mucosa. Indian
Journal of Experimental Biology, 2000; 35(10):1080-1083.
[6] Gupta LN, Jha CB, and Sharma RK. Bilwa, chemical constituents
and medicinal properties. Sacchitra Ayurveda, 2006; pp 290-294.
[7] Kothari S, Minda M, and Tonpay SD. Anxiolytic and Antidepres-
sant Activity of methanolic Extract of Aegle marmelos leaves in
Mice. Indian Journal Pharmacol, 2010; 54(4): 318-328.
[8] Kruawan K, and Kangsadalampai K. Antioxidant activity, phenolic
compound contents and antimutagenic activity of some water ex-
tract of herbs. Thai J Pharm Sci 2006; 30: 28-35.
[9] Lampronti I, Martello D, Bianchi N, Borgatti M, Lambertini E, Piva
R, Jabbar S, Choudhari MS, and Khan MT. Gambari R. Invitro
anti proliferates effects on human tumour cell lines of extract from
the Bangledeshi medicinal plant Aegle marmelos Correa. Phytome-
dicine 2003; 10(4): 300-308.
[10] Maity P and Hansda D. Biological Activity of Crude Extract and
Chemical Constituent of Bael. Indian Journal of Experimental Biol-
ogy, 2009; 47:849–861.
[11] Panda H. Medicinal Plants Cultivation & Their Uses. Asia Pacific
Business Press Inc, 2000.
[12] Parichha S. Bael (Aegle Marmelos) Nature's Most Natural Medicin-
al Fruit. Orissa Review, 2004; 16-17.
[13] Prience PS and Rajadurai M. Preventive effect of Aegle marmelos
leaf extract on isoprenaline- induced myocardial infarction in rats.
Journal of Pharmacy and Pharmacolog, 2005; 57(10): 1353-1357.
[14] Rathore M. Nutrient content of important fruit trees from arid zone
of Rajasthan. Journal of Horticulture and Forestry, 2009; 1(7): 103-
108.
[15] Roy SK and Singh RN. Studies on changes during development and
ripening of bael fruit. Punjab Horticulture Journal, 1980; 20(3&4):
190-197.
[16] Rusia K and Srivastava SK. Antimicrobial activity of some Indian
medicinal plants. Indian Journal of Pharmacological Science,
1988; 50(1): 57-58.
[17] Sharma J, Painuli RM and Gaur RD. Plants used by the rural com-
munities of district Shahjahanpur, Uttar Pradesh. Indian Journal of
Traditional Knowledge, 2010; 9(4): 798-803.
[18] Sharma PK, Bhatia V, Bansal N and Sharma A. A review on bael
tree. Natural Product Radiance, 2007; 6(2):171-178.

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A REVIEW ON MEDICINAL VALUES AND COMMERCIAL UTILITY OF BAEL

  • 1. International Journal of Life-Sciences Scientific Research (IJLSSR), VOLUME 1, ISSUE 1, pp: 5-7 SEPTEMBER-2015 http://ijlssr.com IJLSSR © 2015 All rights are reserved A REVIEW ON MEDICINAL VALUES AND COMMERCIAL UTILITY OF BAEL Pawan Singh Gurjar, Narayan Lal*, Alok Kumar Gupta and Evening Stone Marboh Indian Council of Agricultural Research- National Research Centre on Litchi, (Ministry of Agriculture, Govt. of India), Muzaffarpur, Bihar ABSTRACT- Bael (Aegle marmelos) fruit is one of the blessings from nature for the mankind which is packed with enormous medicinal advantag- es. Its medicinal properties have been described in the ancient medical treatise in Sanskrit, Charaka Samhita. All parts of this tree from stem, bark, root; leaves and fruit at all stages of maturity have medicinal value and have been used as medicine for a long time. Many antioxidant compounds such as flavonoids, flavones, isoflavones, coumarin, anthocyanin, lignans, catechins and isocatechins are found in the fruit pulp (Maity and Hansda, 2009). This plant has tremendous uses listed in Ayurvedic and Unani and Siddha Systems of medicine. This plant is having great potential to cure the disease like diabetes, cholesterol, peptic ulcer, inflammation, diarrhoea, and dysentery, anticancer, cardio protective, anti bacterial, anti fungal, radio protective, anti pyretic, analgesic, constipation, respiratory infection, antioxidant, hepatoprotective, wound healing and many more. The present re- view summarizes the scientific information of various aspects of Aegle marmelos plant used in traditional system of medicine for variety of purpose and its commercial importance. Key Words: Bael, Medicine, Antioxidants, Flavonoids, Lignans, Catechins -------------------------------------------------IJLSSR----------------------------------------------- INTRODUCTION Bael, Aegle marmelos, a plant of Indian origin having tremendous thera- peutic potential and it is belong to family Rutaceae, it is known by the several other names in the different parts of the country and also outside of the country (Sharma et al. 2007). In India, the plant is widely culti- vated particularly in Uttar Pradesh and Bihar. So far around fifteen dis- tinct cultivars, viz., Basti No. 1, Kagzi Gonda, Gonda No. 1, Gonda No. 2, Gonda No. 3, Kagzi Etawah, Sewan Large, Mirzapuri, Deorya Large, Chakaiya, Baghel, Lamba, Pant Shivani and Pant Urvashi have been reported. It is called by different names over different parts of India such as bilva, bel, sadaphal and shriphal. It is used in the worship of Lord Shiva from historic times and hence commonly known as tree of Shiva. Tree is slow-growing and of medium size (12-15 m), generally cultivated in the vicinity of temple garden. It also vigorously grows in dry forest. Almost every part of this tree viz. stems, barks, roots, leaves, flowers & fruits at all stages of maturity have medicinal virtues and have been used Received: 29 July 2015/Revised: 15 August 2015/Accepted: 29 August 2015 in various Ayurvedic medicines since long time for the treatment of specific disorders such as respiratory disorders, constipation, ulcer, di- arrhea, dysentery and many others (Agarwal, 1997). It is also an impor- tant environmental protector as leaves and bark act as a sink by absorb- ing dust and foul and poisonous gases from surrounding atmosphere and makes them clean. Owing to its environment friendly nature, bael is being placed among plant species group called “climate purifiers” which emit a greater percentage of oxygen in sunlight as compared to other plants (Anurag et al., 2004). Due to its endless uses, bael is also known as Mahaphala or Great fruit (Parichha, 2004). Nutritional value Different stdies have shown that bael fruit has significant mineral and vitamin contents. It also contain moisture 64.2%, protein 1.8%, fat 0.2%, mineral 1.5%, fibre 2.2%, carbohydrate 31.8%, calcium 0.06%, phos- phorous 0.05%, potassium 0.6%, vitamin C 0.01%, riboflavin 1.2%, nicotinic acid 0.9%, thiamin 0.01% and iron 0.3% per 100 gm (Rathore, 2009). Its calorific value is 137 (Panda, 2000). Medicinal Value Diarrhoea and dysentery Generally dried fruit pulp and its powder are used for the treatment of diarrhoea. The dried powder is also used as an important remedy for chronic dysentery conditions characterized by alternate diarrhoea and constipation (Sharma et al., 2007). Antidiabetic activity It has been found that bael extract significantly reduces blood urea and cholesterol level in diabetic animals. It also decreases oxidative stress in * Address for Correspondence: C/O- Narayan Lal Scientist (Horticulture-Fruit Science) Indian Council of Agricultural Research-National Research Centre on Litchi (Ministry of Agriculture, Govt. of India) Muzaffarpur - 842 002, Bihar, India Mobile: +91-7677456550 Alternate Email ID: narayan@nrclitchi.org.in Review Article (Open access)
  • 2. International Journal of Life-sciences Scientific Research (IJLSSR), VOLUME 1, ISSUE 1 http://ijlssr.com IJLSSR © 2015 All rights are reserved diabetic animal. Leaf juice is directly employed in Unani system of med- icine for antidiabetic activity (Akhtar et al., 2005). Cardioprotective activity The protective effect was estimated by administration of leaf extract in isoprenaline induced myocardial infarction in experimental animal (Prience and Rajadurai, 2005). Anticancer activity Studies showed that Indian bael extract possess significant antiprolifera- tive effect. It inhibits in vitro proliferation of human tumor cell lines including the leukemic K562 and Tlymphoid Jurhat (Lampronti et al., 2003). Leucoderma Psoralen present in the pulp of Aegle marmelos, increases tolerance of sunlight which aids in the maintenance of normal skin color and thus, it is employed in the treatment of leucoderma (Gupta et al., 2006). Eye infections The leaves of Aegle marmelos are considered an effective treatment for ophthalmia and various eye inflammations such as conjunctivitis (Shar- ma et al., 2010). Constipation The riped bael fruit act as good laxative. It promotes peristaltic move- ments and thus helpful in the removal of fecal matter (Roy and Singh, 1980). Peptic ulcer Bael fruit and leaf infusion has been used for the treatment of peptic ulcer. One of the important advantages of this fruit is that it forms a mu- cilaginous layer on the gastric mucosa and thus prevents interaction of acid with mucosal layer (Goel et al., 2000). Antiburn and Radioprotective Bael fruit powder mixed with mustard oil is used externally for the treatment of burn. It was found in various studies that due to free sca- venging activity, bael fruits have radio protective effect (Kruawan and Kangsadalampai, 2006). Ear Problems The root of this tree possesses astringent activity and is used as a home remedy for curing ear problems. The astringent extract of the roots of Aegle marmelos combined with the antiseptic properties of neem helps in curing ear infection, chronic inflammation and pus discharge. The juice of leaves processed in oil is also used as ear drops to treat ear infec- tion (Rusia and Srivastav, 1988). Antifungal and antibacterial The unsaponifiable matter from the oil obtained from the seeds of Aegle marmelos was effective as antifungal and antibacterial agent (Benerjee et al., 1983). Miscellaneous Properties Bael tree is a holy tree and it has several medicinal properties, some of their practical applications are still under evaluation. Apart from the activity listed above there is little more important activity. The leaves of Aegle marmelos are useful in the treatment of the jaundice and leucor- roea, conjunctivitis and defenses. Fruits give energy and nutrition. It is used in the carminative and astringent and also a good remedy for snake bite. Application are also reported in anemia, fractures, typhoid, coma, colitis (Sharma et al., 2007). The methanolic extract of Aegle marmelos gives the anxiolytic and antidepressant effect (Kothari et al., 2010). General uses Wood is used in house building, cart construction, combs and different household’s articles, leaves as fodder, tooth brushes and chew sticks, flowers used in cooling drinks, stem gum used for adhesive and book binding, a yellow dye obtained from rind of unripe fruit is used in print- ing and whole tree is used as wind barrier. Processed product A large number of bael processed products have been prepared. Preserve and candy are prepared from mature (tender green fruit), fruit squash, fruit pulp, dehydrated bael, Ready to serve (RTS) drink, bael powder, jam, slab, toffee and panjiri are other product prepared from bael fruit. Phytochemicals It was found that leaves, stem and root of this plant contains significant amount of tannins, alkaloids, coumarins and steroids. Different phyto- chemicals are listed in table 1. Table 1: Phytochemicals present in different parts of Aegle marmelos Marketed formulation of Aegle marmelos Some of the marketed formulations of Aegle marmelos produced by different companies in tablets, capsules, syrups, etc. are listed in table 2. Plant part Phytochemicals Leaf Skimmianine, Aeglin, Rutin, γ-sitosterole, β-sitosterol, Flavone,Lupeol, Cineol, Citral, Glycoside, O-isopentenyl, Hallordiol, Mameline, Citronellal, Cuuminaldehyde phenyle- thyle cinnamamides, Euginol, Marmesinin, Aegelin, Glycoside Fruit Marmelosin, Luvangetin, Aurapten, Psoralen, Marmelide, Tannin, Phenol Bark Fagarine, Marmin, Furoquinoline, Alkaloids Seed Essential oil – D- limonene, A-D-phellandrene, Cineol, Ci- tronellal, Citral, P-cyrnene, Cumin aldehyde Root Alkaloid, Halopine, Coumarins, Terpines.
  • 3. International Journal of Life-sciences Scientific Research (IJLSSR), VOLUME 1, ISSUE 1 http://ijlssr.com IJLSSR © 2015 All rights are reserved Table 2: Marketed formulation of Aegle marmelos Marketed formulations Company Name Chyawanprash Himalaya Aegle Marmelos Capsules La-Medicca (India) Pvt. Limited Leucare capsules Shrey Nutraceuticals & Herbals Entrostat Syrup Ambika Medico Kof-Rid Syrup Ambika Medico Pregeight Sydler Remedies Pvt. Ltd. Ojamin Tates Remedies Manasamithravatakram Oushadhi Pushyanugam gulika Oushadhi Vilwadi gulika Oushadhi Glucomap Maharishi Ayurveda Ulco Bliss Tablets Bliss ayurveda Capsule Bilv Giri Ayurvedic Sanjivani R-Qunol Syrup Vatsal Ayurvedic Products (P) ltd REFERENCES [1] Agarwal VS. Rural economics of medicinal plants: Vegetation in the forest. In: Drug plants of India. New Delhi, Kalyani Publishers, 1997; pp 6- 44. [2] Akhtar J, Jamil S, and Azhar MU. Diabetes mellitus: Prevention and management. Natural Product Radiance, 2005; 4(5): 413-415. [3] Anurag S, Sharma HK, Pragati K, and Ashutosh U. Bael (Aegle marmelos Correa) products processing: A review. African Journal of Food Science, 2014; 8(5): 204–215. [4] Banerjee AK, Kaul VK, and Nigam SS. Chemical, microbial and antihelminthic examination of the seeds of Aegle marmelos Correa. Indian Drugs, 1983; 21(5): 217-218. [5] Goel RK, Maiti RN, Manickan M, and Ray AB. Antiulcer activity of naturally occurring ptrano coumarin and isocoumarin and their effect on prostanoid synthesis using human colonic mucosa. Indian Journal of Experimental Biology, 2000; 35(10):1080-1083. [6] Gupta LN, Jha CB, and Sharma RK. Bilwa, chemical constituents and medicinal properties. Sacchitra Ayurveda, 2006; pp 290-294. [7] Kothari S, Minda M, and Tonpay SD. Anxiolytic and Antidepres- sant Activity of methanolic Extract of Aegle marmelos leaves in Mice. Indian Journal Pharmacol, 2010; 54(4): 318-328. [8] Kruawan K, and Kangsadalampai K. Antioxidant activity, phenolic compound contents and antimutagenic activity of some water ex- tract of herbs. Thai J Pharm Sci 2006; 30: 28-35. [9] Lampronti I, Martello D, Bianchi N, Borgatti M, Lambertini E, Piva R, Jabbar S, Choudhari MS, and Khan MT. Gambari R. Invitro anti proliferates effects on human tumour cell lines of extract from the Bangledeshi medicinal plant Aegle marmelos Correa. Phytome- dicine 2003; 10(4): 300-308. [10] Maity P and Hansda D. Biological Activity of Crude Extract and Chemical Constituent of Bael. Indian Journal of Experimental Biol- ogy, 2009; 47:849–861. [11] Panda H. Medicinal Plants Cultivation & Their Uses. Asia Pacific Business Press Inc, 2000. [12] Parichha S. Bael (Aegle Marmelos) Nature's Most Natural Medicin- al Fruit. Orissa Review, 2004; 16-17. [13] Prience PS and Rajadurai M. Preventive effect of Aegle marmelos leaf extract on isoprenaline- induced myocardial infarction in rats. Journal of Pharmacy and Pharmacolog, 2005; 57(10): 1353-1357. [14] Rathore M. Nutrient content of important fruit trees from arid zone of Rajasthan. Journal of Horticulture and Forestry, 2009; 1(7): 103- 108. [15] Roy SK and Singh RN. Studies on changes during development and ripening of bael fruit. Punjab Horticulture Journal, 1980; 20(3&4): 190-197. [16] Rusia K and Srivastava SK. Antimicrobial activity of some Indian medicinal plants. Indian Journal of Pharmacological Science, 1988; 50(1): 57-58. [17] Sharma J, Painuli RM and Gaur RD. Plants used by the rural com- munities of district Shahjahanpur, Uttar Pradesh. Indian Journal of Traditional Knowledge, 2010; 9(4): 798-803. [18] Sharma PK, Bhatia V, Bansal N and Sharma A. A review on bael tree. Natural Product Radiance, 2007; 6(2):171-178.