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By : Marwa Mahmoud Khalifa
Hematology & Internal Medicine Specialist

 Plain X ray
 CT
 MRI
 US
 Angiography
 PET scan
Modalities

 Fractures of the bones of the skull
 Pituitary tumors
 Bone defects (birth/ Myeloma/metabolic)
 Evaluate the nasal sinuses
 Detect cerebral calcification .
X ray skull

Maxillary sinusitis

Thalassemia

Hyper parathyroidism

Skull fracture

MM

Acromegalic skull

Enlarged sella

CT

 Unenhanced CT
 CT with contrast
 CT angiogram
 CT venogram
Types of CT

 Hemorrhage
 Ischemic stroke
 DLC
 Seizure
 Headache
Unenhanced CT
Indications

 Assessment of intracranial mass lesion
 Primary malignancy vs. mets
 Abscess/infection
 eg. meningitis, toxoplasmosis (HIV+)
Enhanced CT
Indications

Spontaneous SAH
 Cerebral artery aneurysm
 AVM
 Ischemic stroke
 Occlusive thrombus
 Dissection
CT Angiography
Indications

 Dural venous sinus thrombosis
CT Venography
Indications
F
O
F
P
F
T
O
F
P
O
P
P
T T
F
O
A. Orbit
B. Sphenoid Sinus
C. Temporal Lobe
D. External Auditory Canal
E. Mastoid Air Cells
F. Cerebellar Hemisphere
A. Frontal Lobe
B. Frontal Bone (Superior Surface of Orbital Part)
C. Dorsum Sellae
D. Basilar Artery
E. Temporal Lobe
F. Mastoid Air Cells
G. Cerebellar Hemisphere
A. Falx Cerebri
B. Frontal Lobe
C. Anterior Horn of Lateral Ventricle
D. Third Ventricle
E. Quadrigeminal Plate Cistern
F. Cerebellum
A. Anterior Horn of the Lateral Ventricle
B. Caudate Nucleus
C. Anterior Limb of the Internal Capsule
D. Putamen and Globus Pallidus
E. Posterior Limb of the Internal Capsule
F. Third Ventricle
G. Quadrigeminal Plate Cistern
H. Cerebellar Vermis
I. Occipital Lobe
A. Genu of the Corpus Callosum
B. Anterior Horn of the Lateral Ventricle
C. Internal Capsule
D. Thalamus
E. Pineal Gland
F. Choroid Plexus
G. Straight Sinus
A. Falx Cerebri
B. Frontal Lobe
C. Body of the Lateral Ventricle
D. Splenium of the Corpus Callosum
E. Parietal Lobe
F. Occipital Lobe
G. Superior Sagittal Sinus
A. Falx Cerebri
B. Sulcus
C. Gyrus
D. Superior Sagittal Sinus


Normal Enhanced CT

Falx cerebri/dura
Calcifications
Calcifications
Choroid plexus
Calcifications
 Pineal body
Calcifications
 Basal ganglia

Motion Artefact
(streaking pattern)

Metallic Artefact
(star shaped artifact)

Subarachnoid
Hemorrhage

Subdural
hemorrhage

1- Acute SDH
high density fluid collection layering along the cerebral convexity,
2- Subacute SDH (1-2 weeks)
“isodense” to grey matter
3- Chronic SDH (> 2 weeks)
“hypodense” to gray matter
4- Acute-on-chronic
hyperdense acute hemorrhage intermixed or layering dependently within the
chronic collection.
SDH – CT Features

Subdural Hematoma

Epidural
hemorrhage

Intracerebral
hemorrhage

Add htn image here
Intracerebral
hemorrhage

Ischemic Left MCA Stroke

Chronic Ischemic
change =
Encephalomalacia

Global ischemia

Brain oedma

Hydrocephalus

Brain Abscess
 Primary tumours:
 Astrocytoma
 Glioblastoma
 Oligodendroglioma
 Meningioma
 Secondary tumours (mets):
 Most commonly supratentorial
Mass Lesions


The two most common
types of MR images are…
 T1-weighted MR images-
useful to look at normal
anatomy of the brain
 T2-weight MR images -
useful to look at
abnormal processes (or
pathology) in the brain
What is bright/dark on
T1?
Fat is bright
White matter (inner
part of brain) is
brighter than gray
matter (cortex or
outer part of the
brain)
Water (CSF) is dark
What is bright/dark on
T2?
Water is bright
Blood is bright
White matter is
darker than gray
matter
Brain tumor
T1 SAGITTAL MR
Pituitary Adenoma
T2* MRV on a Seizure Patient

Conventional Angiography
Aneurysm
Round (‘berry’) shape
At Vessel bifurcation
Cranial ultrasound
 Cranial ultrasound uses reflected sound waves to
produce pictures of the brain and the inner fluid
chambers (ventricles) through which cerebrospinal fluid
(CSF) flows.
 This test is most commonly done on babies to evaluate
complications of premature birth.
 In adults, cranial ultrasound may be done to visualize
brain masses during brain surgery.
INDICATIONS
 Prematurity
 Increased head circumference
 Persisting large fontanelle
 Trauma
 Known hypoxia
 Follow up of known pathology
 Failure to thrive
 Suspected intracranial mass or infection
LIMITATIONS
 If the anterior fontanel is very small or closed your
visibility will be reduced or completely obscured.
 Even with a large fontanelle, the peripheral extremes of
the brain are obscured from view.
Doppler of the carotid
bifurcation
Brain Imaging using
18-fluoro-2-deoxyglucose
(FDG)-PET
Procedure
 Patients should fast for at least 4 hrs
 Check blood glucose levels prior to the FDG
administration. When hyperglycemia is present (>160
mg/dl), there is increased competition of elevated plasma
glucose with FDG at the carrier enzyme Therefore FDG
uptake is reduced .
 Empty the bladder for maximum comfort during the
study. Advice the patient to void again after the scanning
session to minimize radiation exposure.
 The patients should be positioned comfortably in a quiet
dimly lit room several minutes before FDG-administration
and during the uptake phase of FDG (at least 20 min).
They should be instructed not to speak, read or otherwise
be active.
Indications
A..Epilepsy.
B. Dementia. Indications include early diagnosis and
differential diagnosis of dementing disorders, like
Alzheimer's disease and fronto-temporal dementia .
C. Neurooncology. FDG-PET is predominantly used in
differential diagnosis of cerebral lumps, detection of
viable tumor tissue (i.e. recurrence) and for non-invasive
grading
D. FDG-PET is clinically used for a number of other
indications, e.g. movement disorders or cerebrovascular
disease .
Contra indications:
A. Pregnancy (mothers should interrupt breast feeding for
24hrs if SPET is indicated)
B. Evident lack/unability of cooperation
Patient should be able to lie still for 30 min to 1 hr. If
sedation is necessary it should be performed as late as
possible. It should be intended to administer FDG
prior to sedation
Cerebral PET scan
Neuro radiology   neuroimaging

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