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INFORMATIZACIJA V
ZDRAVSTVU
doc. dr. Matic Meglič, dr. med., MBA
Predstojnik Centra za Informatiko v Zdravstvu
NIJZ
ZA ZAČETEK: KOLIKO E- SMO?
Pametni mobilniki?
Tablični računalniki?
Aplikacije za klinično delo (elektronski zdravstveni karton)?
App-i za diagnostiko, izračun tveganj, kazalnikov?
Wiki, klinično znanje? Medscape, MD Consult
Twitter? LinkedIn? (Facebook)
Vpliv tehnološkega razvoja
na zdravje in zdravstveni sistem:
•
•
•
•
•
•
•

Dostopne tehnologije
24/7
‚The quantified self‘
Opolnomočeni pacient
Paradigma eJavnoZdravje
Personalizirana medicina
Big Data, Big Analytics

Meglič, NCCR2013
Kje lahko eZdravje pomaga?

x

x

• Pri vseh ključnih načinih ukrepanja
– Preventiva (primarna, sekundarna, terciarna)
– Zdravljenje

Meglič, Brodnik, IGI2009

x
x
x

blog.urbansedlar.com/
x

forbes.com
mladez.rs
ohgizmo.com
telecareconsulting.com
informaitonweek.com
x
Azmo the dragon
SLOVENSKE IZKUŠNJE
Aplikativna projekta eDepresija in eOskrba
Koordinacija
zdravljenja depresije
• Intervencija:
– Spletno/mobilno
okolje
– Koordinator oskrbe
– Klinična pravila
– Samoocenjevanje
– Opomniki
eOskrba: KOPB, diabetes, hujšanje…
4

Enaki principi
• -koordinacija
oskrbe
• -kl. smernice
• -vključevanje pac.
ALI STVARI DELUJEJO?
Izboljšanje simptomov
35
30
25

Število BDI na začetku SD
Kontrole 10
28,70
8.34
15
Primeri
12
29,50
8.15
10
t = 0.23; P = .82
5 t; P
20

BDI na koncu
17,80
7,97
t = 2.33; P = .03

SD
Kontrole
7.91
Primeri
8.05

0

BDI na začetku

BDI na koncu

Razpoložljivi
primeri

Skupina
primerov

Skupina
kontrol

Zdravi na začetku

0/21 (0%)

0/25 (0%)

Zdravi na koncu

9/12 (75%) 1/10 (10%)
Meglic et al., JMIR 2010
INFORMATIKA IN
ZDRAVSTVENO VARSTVO
Meglič, Brodnik, IGI2009
Poročanje
-MZ
-ZZZS
-IVZ/ZZV

eRecept
eNapotnica
eOdpustno pismo
eIzvid
ePoročilo/Obrazec
Povezovanje
do
pacienta, izva
jalcev
Orodja za
proces dela

Ekspertni
sistemi:

Meglič, Brodnik, IGI2009

Izmenjava
dokumentov, podat
kov

HIS, EZK

Triaža, ocen
a tveganja

Procesna
orodja

Telemedicina,
Koordinacija

Opolnomočenje
pacienta

LIS, PACS

Podporna orodja (€,
logistika, nabava,
poročanje

Interakcije, KI
zdravil

Diagnostična
orodja ipd.

Dostop do
znanja
INFORMATIKA V JAVNEM
ZDRAVJU
Za kaj gre?
Nova paradigma: eJavnoZdravje

• Personalizacija
• Infomediacija in opolnomočenje
• Infodemiologija
PRILOŢNOSTI
Skupine s
tveganim
vedenjem
Ciljane
kampanje
Vključevanje
uporabnikov

®hackingalert
NOVO ZNANJE
• Frost et al. JMIR 2011
• taking certain drugs “offlabel“ with higher perceived
efficacy
• side effect of amitriptyline
(dry mouth) as the purpose
for taking the drug (e.g. to
treat excessive saliva).
Epidemiologija, nadzor
•

•

•

•

Infodemiology, Infoveillanc
e: new concepts in health /
PH research
web (search engine
data), patient social
networks and
microblogging platforms as
source of knowledge and
live data
integration and mining of
data from various online
sources to discover new
clinical and population
patterns i.e. disease
outbreaks and syndromic
surveillance
Eysenbach 2009

Eysenbach Infovigil, later Google Flu Trends
Twitter za nadzor izbruhov bolezni
• Signorini 2011, Kim 2012, both PLoS ONE: Influenzalike-illness
• ‚Twitter traffic can be used … to estimate disease
activity in real time, i.e., 1–2 weeks faster than
current practice allows‘
PREVENTIVA IN
PRESEJANJE:
Boljše razumevanje ciljne populacije
Who are our users?
User behaviour
What content is relevant for our
users?
PRIMER AKTIVNEGA
VKLJUČEVANJA
I‘M A FAN OF LIFE
Izziv: osveščati splošno populacijo o tem, kako
zmanjšati tveganje za nastanek raka.
Način: Promocija JZ vsebin preko spletnih socialnih
omreţij z uporabo prijemov gamifikacije in
‚celebrity branding‘
The rise of Gamification - when humans beat
computers ‚back‘
Jeopardy

FOLDIT:
…scientific
advancement is
possible if even a small
fraction of the energy
that goes into playing
computer games can
be channelled into
scientific discovery.
Rezultati
• App na voljo 3 mesece
• Splet: 166
16.800 like-ov
• App: 5.200 uporabnikov
Vpliv oglaševanja
2500

FB Adverts
stop

2000

FB Adverts
stop

1500

1000

500

0

App Start

FB Adverts
stop
FB Adverts
start
FB Adverts start

Weekly Active
and 30-day cou
engaged with y
(Unique Users)
Daily Added Ap
app or connect
Follows accept
Service. (Total
Daily Removed
premissions fo
your Connect s

FB Adverts
start
User engagement
E-ZDRAVJE IN
RAZISKOVALNO DELO
IT services and tools to make a health care
researcher‘s life easier
• Knowledge discovery (online
publishing was the key
enabler for Open Access
Model)
– Smart filtering (i.e. PubMed)
and push notifications (using
email, RSS, apps, twitter)
– Shared knowledge discovery
(shared feeds, shared
references i.e. Mendeley)

• Collaboration
– ResearchGate (connect)
– FoldIT
– http://nhshackday.com/
arstechnica.com
blog.library.si.edu/
IT services and tools to make a health
care researcher‘s life easier (2)
• Access to new data sources online:
– microblogging data, ‚live‘ trend analysis,
– Personal Health Data (the quantified self, online
excercise mapping)
– Social Networks in Health and Health Care (PLM)

• Interaction with research subjects
– the connected human (Smartphones, tablets,
monitoring devices (wearable/ingestible/implantable)
– Ease of data acquisition: from Online Questionnaires,
portable monitoring devices, RFID infrastructure, etc.
– New ways to interact and acquire data
Trial search tool for patients
Novi buzzword: Open Data
• Publicly available large
datasets
• Coupled with generic
APIs they are super easy
to use and drill-down.
•
•

http://www.openprescribing.org/
http://www.openhealthcare.org.uk/

• Efforts to open up
pharma data.. Tough but
there are
improvements.
eZdravje kot čarobna paličica?
•

•

•

Using the Internet for health purposes was
associated with slightly increased
depression (due to increased
rumination, unnecessary alarm, or overattention to health problems) Bessière et
al 2010 JMIR
Suicide: phone (telemedicine) follow-up
was effective in reducing suicidal ideation
but not effective in reducing actual selfharm
The QALY gain by patients using telehealth
in addition to usual care was similar to
that by patients receiving usual care
only, and total costs associated with the
telehealth intervention were higher.
Telehealth does not seem to be a cost
effective addition to standard support and
treatment.
Ko se ni izšlo…
Problem poslovnega modela:
• Spletno arhiviranje (za
reference) – WebCite
www.webcitation.org
• Kolaborativno znanje (rak):
caBIG
(https://cabig.nci.nih.gov)
Problem dodane vrednosti:
• Skoraj vsi PHRji:
GoogleHealth, MedGle, Rev
olutionHealth, NHS
PHR, (HealthVault)
Ko se ni izšlo
Problem vgraditve
klinične vsebine:
• Diagnostika kožnih
sprememb: delujejo
samo tiste, kjer
specialist pregleda
sliko
(Zlo?)raba v tržne
namene:
• Nike+

3 of 4 smartphone applications incorrectly
classified 30% or more of melanomas as
unconcerning. Reliance on these
applications … can delay the diagnosis of
melanoma and harm users.
ZA KONEC
Neizogibnost
Hitrost
Previdnost ni odveč – klinična
preizkušenost
Financiranje storitev?

Vabljeni k sodelovanju!
matic.meglic@nijz.si
ehealth.si

matic_meglic
Matic Meglic

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eZdravje / Informatizacija v zdravstvu - predavanja za staziste

  • 1. INFORMATIZACIJA V ZDRAVSTVU doc. dr. Matic Meglič, dr. med., MBA Predstojnik Centra za Informatiko v Zdravstvu NIJZ
  • 2. ZA ZAČETEK: KOLIKO E- SMO? Pametni mobilniki? Tablični računalniki? Aplikacije za klinično delo (elektronski zdravstveni karton)? App-i za diagnostiko, izračun tveganj, kazalnikov? Wiki, klinično znanje? Medscape, MD Consult Twitter? LinkedIn? (Facebook)
  • 3. Vpliv tehnološkega razvoja na zdravje in zdravstveni sistem: • • • • • • • Dostopne tehnologije 24/7 ‚The quantified self‘ Opolnomočeni pacient Paradigma eJavnoZdravje Personalizirana medicina Big Data, Big Analytics Meglič, NCCR2013
  • 4. Kje lahko eZdravje pomaga? x x • Pri vseh ključnih načinih ukrepanja – Preventiva (primarna, sekundarna, terciarna) – Zdravljenje Meglič, Brodnik, IGI2009 x
  • 9. Koordinacija zdravljenja depresije • Intervencija: – Spletno/mobilno okolje – Koordinator oskrbe – Klinična pravila – Samoocenjevanje – Opomniki
  • 10.
  • 11. eOskrba: KOPB, diabetes, hujšanje… 4 Enaki principi • -koordinacija oskrbe • -kl. smernice • -vključevanje pac.
  • 13. Izboljšanje simptomov 35 30 25 Število BDI na začetku SD Kontrole 10 28,70 8.34 15 Primeri 12 29,50 8.15 10 t = 0.23; P = .82 5 t; P 20 BDI na koncu 17,80 7,97 t = 2.33; P = .03 SD Kontrole 7.91 Primeri 8.05 0 BDI na začetku BDI na koncu Razpoložljivi primeri Skupina primerov Skupina kontrol Zdravi na začetku 0/21 (0%) 0/25 (0%) Zdravi na koncu 9/12 (75%) 1/10 (10%) Meglic et al., JMIR 2010
  • 16. Poročanje -MZ -ZZZS -IVZ/ZZV eRecept eNapotnica eOdpustno pismo eIzvid ePoročilo/Obrazec Povezovanje do pacienta, izva jalcev Orodja za proces dela Ekspertni sistemi: Meglič, Brodnik, IGI2009 Izmenjava dokumentov, podat kov HIS, EZK Triaža, ocen a tveganja Procesna orodja Telemedicina, Koordinacija Opolnomočenje pacienta LIS, PACS Podporna orodja (€, logistika, nabava, poročanje Interakcije, KI zdravil Diagnostična orodja ipd. Dostop do znanja
  • 18. Nova paradigma: eJavnoZdravje • Personalizacija • Infomediacija in opolnomočenje • Infodemiologija
  • 20. NOVO ZNANJE • Frost et al. JMIR 2011 • taking certain drugs “offlabel“ with higher perceived efficacy • side effect of amitriptyline (dry mouth) as the purpose for taking the drug (e.g. to treat excessive saliva).
  • 21. Epidemiologija, nadzor • • • • Infodemiology, Infoveillanc e: new concepts in health / PH research web (search engine data), patient social networks and microblogging platforms as source of knowledge and live data integration and mining of data from various online sources to discover new clinical and population patterns i.e. disease outbreaks and syndromic surveillance Eysenbach 2009 Eysenbach Infovigil, later Google Flu Trends
  • 22. Twitter za nadzor izbruhov bolezni • Signorini 2011, Kim 2012, both PLoS ONE: Influenzalike-illness • ‚Twitter traffic can be used … to estimate disease activity in real time, i.e., 1–2 weeks faster than current practice allows‘
  • 24. Who are our users?
  • 26. What content is relevant for our users?
  • 28. I‘M A FAN OF LIFE Izziv: osveščati splošno populacijo o tem, kako zmanjšati tveganje za nastanek raka. Način: Promocija JZ vsebin preko spletnih socialnih omreţij z uporabo prijemov gamifikacije in ‚celebrity branding‘
  • 29. The rise of Gamification - when humans beat computers ‚back‘ Jeopardy FOLDIT: …scientific advancement is possible if even a small fraction of the energy that goes into playing computer games can be channelled into scientific discovery.
  • 30.
  • 31.
  • 32.
  • 33.
  • 34.
  • 35. Rezultati • App na voljo 3 mesece • Splet: 166 16.800 like-ov • App: 5.200 uporabnikov
  • 36. Vpliv oglaševanja 2500 FB Adverts stop 2000 FB Adverts stop 1500 1000 500 0 App Start FB Adverts stop FB Adverts start FB Adverts start Weekly Active and 30-day cou engaged with y (Unique Users) Daily Added Ap app or connect Follows accept Service. (Total Daily Removed premissions fo your Connect s FB Adverts start
  • 39. IT services and tools to make a health care researcher‘s life easier • Knowledge discovery (online publishing was the key enabler for Open Access Model) – Smart filtering (i.e. PubMed) and push notifications (using email, RSS, apps, twitter) – Shared knowledge discovery (shared feeds, shared references i.e. Mendeley) • Collaboration – ResearchGate (connect) – FoldIT – http://nhshackday.com/
  • 41. IT services and tools to make a health care researcher‘s life easier (2) • Access to new data sources online: – microblogging data, ‚live‘ trend analysis, – Personal Health Data (the quantified self, online excercise mapping) – Social Networks in Health and Health Care (PLM) • Interaction with research subjects – the connected human (Smartphones, tablets, monitoring devices (wearable/ingestible/implantable) – Ease of data acquisition: from Online Questionnaires, portable monitoring devices, RFID infrastructure, etc. – New ways to interact and acquire data
  • 42. Trial search tool for patients
  • 43.
  • 44. Novi buzzword: Open Data • Publicly available large datasets • Coupled with generic APIs they are super easy to use and drill-down. • • http://www.openprescribing.org/ http://www.openhealthcare.org.uk/ • Efforts to open up pharma data.. Tough but there are improvements.
  • 45. eZdravje kot čarobna paličica? • • • Using the Internet for health purposes was associated with slightly increased depression (due to increased rumination, unnecessary alarm, or overattention to health problems) Bessière et al 2010 JMIR Suicide: phone (telemedicine) follow-up was effective in reducing suicidal ideation but not effective in reducing actual selfharm The QALY gain by patients using telehealth in addition to usual care was similar to that by patients receiving usual care only, and total costs associated with the telehealth intervention were higher. Telehealth does not seem to be a cost effective addition to standard support and treatment.
  • 46. Ko se ni izšlo… Problem poslovnega modela: • Spletno arhiviranje (za reference) – WebCite www.webcitation.org • Kolaborativno znanje (rak): caBIG (https://cabig.nci.nih.gov) Problem dodane vrednosti: • Skoraj vsi PHRji: GoogleHealth, MedGle, Rev olutionHealth, NHS PHR, (HealthVault)
  • 47. Ko se ni izšlo Problem vgraditve klinične vsebine: • Diagnostika kožnih sprememb: delujejo samo tiste, kjer specialist pregleda sliko (Zlo?)raba v tržne namene: • Nike+ 3 of 4 smartphone applications incorrectly classified 30% or more of melanomas as unconcerning. Reliance on these applications … can delay the diagnosis of melanoma and harm users.
  • 48. ZA KONEC Neizogibnost Hitrost Previdnost ni odveč – klinična preizkušenost Financiranje storitev? Vabljeni k sodelovanju!

Notas del editor

  1. SignifikancaObe skupini: pomembno izboljšanje simptomov (BDI-II):Skupina, ki je uporabljala intervencijo: bistveno večje izboljšanjePodobno kot Robertsonova.