Metrohm has taken ion chromatography to an entirely new level. We are proud to offer you the Professional IC product family – the first ion chromatography systems made up of intelligent components for: - Anions and cations in drinking water - Ultratrace analysis - Ions in complex sample matrices - Method development in R & D Your key benefits with Metrohm ion chromatography: * High sensitivity right down to the ppt level * Accurate and reproducible results * Ease of use due to intelligent IC components * monitoring and controlling functions *Metrohm Inline Sample Preparation (MISP) * Low cost of ownership * Reliable and affordable service and support

1. Intelligent
Ion Chromatography
850 Professional IC
872 Extension Module
858 Professional Sample Processor

2. Professional ion chromatography
02 Metrohm ion chromatography
Metrohm guarantees optimal solutions in ion chroma- Professional IC guarantees excellent results, gapless sys-
tography based on innovative and creative solutions tem monitoring, complete traceability of all actions and
throughout the last twenty years – with high-tech, many the simple operation of even complex procedures.
years of application know-how, Swiss quality standards
and a reasonable pricing policy, both in acquisition and The 850 Professional IC is an extremely compact system
running costs. Metrohm 850 Professional IC, 872 Exten- with all the flexibility of modular design. It adapts itself to
sion Module and 858 Professional Sample Processor are the particular application and is equipped for all future
Swiss Engineered and Swiss Made. tasks. Any existing 850 Professional IC system can be
further expanded with 872 Extension Modules. Profes-
Built-in intelligence sional IC also stands for a robust system setup using
Metrohm IC is ion chromatography from the technology high-end components. A long working life with low run-
leader. The 850 Professional IC is the first professional ion ning costs is guaranteed.
chromatography system with intelligent system compo-
nents:
• Intelligence in the hardware of the 850 Professional IC,
• Intelligence in the MagIC NetTM software,
• Intelligence in the Metrosep iColumns.

3. 03
Highlights
• Highly compact modular system
• MagIC NetTM software for intuitive and simple operation
• Comprehensive monitoring and control functions
• Complies with GLP and FDA requirements
• Flexible assembly and extension: from isocratic cation system up to quaternary high-
pressure gradient system for anion analysis
• Combined third-generation anion-cation systems
• MISP – Metrohm Inline Sample Preparation – patented and unique sample preparation
• Intelligent system components: iPump, iDetector, iColumn, intelligent Dosing Units
• Professional Sample Processor for any required volumes and extensive liquid handling
operations
• High-precision Dosino technology
• Broad range of detection possibilities
• Swiss Engineered – Swiss Made

4. Flow path features
04 The flow path of the 850 Professional IC is metal-free
and biocompatible. Most applications permit Green Che-
Another option is preparing the eluent directly inline. This
is done by connecting the 849 Level Control and the 800
mistry without toxic solvents, corrosive eluents or even Dosino to the 850 Professional IC system. Controlled by
cartridges that have to be disposed of as hazardous MagIC NetTM, the 849 Level Control monitors the eluent
waste. Nevertheless the system is 100% solvent-resistant level while the Dosino carries out all the required dosing
and withstands even rough surroundings. Eluents are and liquid-handling operations. In this case, eluent pre-
automatically degassed inline and the MagIC NetTM soft- paration runs parallel to the determination. The system
ware ensures that they are always fresh. allows continuous ion chromatographic analyses over a
month without any manual eluent preparation being
Automated eluent preparation required.
The time-consuming manual preparation of the eluents
can be automated. One of the options offered by
Metrohm to realize this is the 845 Eluent Synthesizer, The error-prone and time-consuming eluent pre-
which prepares eluents from up to four freely selectable paration can be automated at small additional
concentrates and one main component. Compared to cost.
the traditional manual eluent preparation, the fully auto-
mated system guarantees precise mixtures and excellent
batch-to-batch reproducibility by simple mouse-click in
the «Mix Control» program.

5. 05
Gradients – if necessary
High-pressure or low-pressure gradients are used only method development or as eluent selector for the auto-
where they are really needed. Gradient form and mixing matic switchover from one application to another.
are freely selectable: step, linear, convex and concave
gradient functions are available and can be combined. The gradient systems are available with chemical suppres-
sion, with sequential suppression or without suppression,
The 850 Professional IC system is available as a high- depending on the requirements. They can be combined
pressure or low-pressure gradient version. Moreover, all with a broad range of detectors and are suitable for hy-
850 Professional IC systems can be operated with the droxide as well as carbonate gradients. When working
Dosino Gradient as well. with sequential suppression and conductivity detection,
the flexibility of the carbonate/hydrogencarbonate elu-
The high-pressure gradient system can be expanded to ents can be combined with the low background conduc-
a quaternary gradient system with the 872 Extension tivity of an hydroxide eluent by the CO2 suppression
Module. applied after the chemical suppressor.
The low-pressure gradient version is the economic alter- For gradient applications we recommend the high-capa-
native to the powerful high-pressure gradient system. city Metrohm Suppressor Module «MSM-HC» to be used
The low-pressure gradient module can also be used for for chemical suppression.

6. Intelligent components for an intelligent system
06 Self-monitoring for zero fault tolerance
The intelligent system components monitor and optimize
Intelligent system
850 Professional IC is a system composed of discrete,
all functions, which are, if required, documented in an intelligent modules that are optimally matched to one
FDA-compliant form. The configuration of the system is another. The way from the sample to a precise result has
as simple as can be imagined, as the components log now become easier, as the system thinks for itself and
themselves in automatically and provide the MagIC NetTM makes logical decisions. This prevents operating errors
software with all the relevant information. The way from and improves reliability of results.
the sample to a precise result has become quicker as
even complex sample preparation steps are now carried The 850 Professional IC is a complex and very efficient
out inline and automatically. If necessary, the system will system that can still be operated simply and intuitively
also automatically optimize sample preconcentration or with the MagIC NetTM software. This applies for both
sample dilution. The optimal operation of the 850 Pro- power users with complex applications and complicated
fessional IC and the results are monitored. If a parameter calculations and users who value «one-button opera-
leaves the predefined range then the user is informed by tion». Any user level is possible. Innovation, flexibility and
E-Mail or SMS. extremely simple operation result from the intelligence of
the 850 Professional IC, the 872 Extension Module, the
858 Professional Sample Processor and the MagIC NetTM
software.

7. 07
Superior flexibility
The 850 Professional IC system is highly flexible. The prin- tor is a state-of-the-art, powerful and intelligent detec-
ciple of discrete modules combined into a system means tor. If your samples require a different detection method,
that users are perfectly prepared to meet ever new and you can use UV/VIS detection, electrochemical methods
more demanding challenges. Read more about new or mass spectroscopic methods as well.
options with the 872 Extension Modules from page 22
on. Moreover, all 850 Professional IC systems can be Flexibility in the choice of the separation coulumn
combined with Metrohm’s unique Inline Sample Prepa- We offer you a wide range of different columns. Depend-
ration techniques (page 13). They provide for a fully ing on your application you can choose columns with
automated and reliable analysis of liquid, solid and even various base materials, selectivity, capacity and dimen-
gaseous samples in a single run. sions. Besides columns with an inner diameter of
4 mm we can even offer you 2 mm columns to reduce
Flexibility in the use of the detection method eluent consumption. For these «microbore columns» we
Conductivity detection is the most frequently used detec- have developed our new chemical suppressor «MSM-LC».
tion method in ion chromatography. Metrohm’s iDetec-

8. 850 Professional IC system at a glance
08
6
5
1 3
2
4
7
8

9. 1 Housing
All components of the 850 Professional IC are easily
6 Detection
After their separation on the iColumn the ions pass,
09
accessible and well laid out. Extensions can be made e.g., the intelligent conductivity detector of the 850
at any time – the system grows to meet your require- Professional IC. The detector transfers the digitized
ments. The flow path for the application is metal-free signal directly to the MagIC NetTM software. Outstanding
and already preinstalled. The transparent door allows temperature stability, a Faraday cage and the latest
visual monitoring during the analysis. generation of DSP – Digital Signal Processing – guaran-
tee highest precision. The wide measuring range of the
2 Eluent transfer iDetector of 0...15 000 μS/cm ensures accurate and
The iPump is a central element of the 850 Professional precise results from traces to percentage – in one
IC. Its extremely low pulsation translates into low noise determination.
and consequently in to highest sensitivity of the ana-
lytical system. The iPump optimizes its flow rate on its 7 Automation
own; its memory chip stores all the important infor- The 858 Professional Sample Processor is more than
mation. just a sample changer. Equipped with pumps, injection
valve and Dosinos it makes an integral contribution to
3 iColumns Inline Sample Preparation and Liquid Handling. More
The iColumn, the analytical separating column, is the than 30 different sample racks are recognized auto-
heart of any application. Thanks to the iColumn tech- matically, which means that with respect to their form
nology, the optimal chromatographic conditions are and volume very individual sample vessels can be used.
stored on a chip, which prevents damage due to ope- The standard version accommodates 148 samples.
rational errors. Moreover, if the iColumn is used on a
different Professional IC system no information is lost 8 Software
which means that the analytical process is traceable Clear symbols, well-laid-out presentation, intuitive ope-
without any gaps. ration, «one-button IC»: that‘s MagIC NetTM. Complete
system monitoring, control cards, comfortable database
4 Column thermostat – hot or cold? functions are additional features of MagIC NetTM, the
Any temperature between 0 °C and 80 °C is possible. intelligent software for controlling the 850 Professional
The analytical columns and the applications determine IC and evaluating the data. All 850 Professional IC
how hot or cold the column thermostat has to be. It instruments, all intelligent Compact IC instruments,
can contain up to two iColumns, a further column can 872 Extension Modules, 858 Professional Sample
be operated externally at room temperature. Processors, 800 Dosinos and iColumns are automati-
cally recognized, monitored and controlled.
5 Suppression
Sequential or chemical suppression – both allow highly
sensitive analyses due to very low background conduc-
tivity. The 850 Professional IC is now available not only
with the «MSM II» chemical suppressor but also with
the high-capacity «MSM-HC» suppressor or with the
low-capacity «MSM-LC» suppressor. With 0.2 nS/cm
these suppressors have the lowest noise of all suppres-
sors. Metrohm suppressors are extremely robust and
resistant to both solvents and pressure; the reason why
they come with a 10-year warranty.

10. Suppression
10 Ion chromatographic analysis, especially that of anions,
uses chemical as well as sequential suppression to reduce
pressor reaction. This allows the determination of anions
with the flexibility of carbonate/bicarbonate eluents while
background conductivity and increase sensitivity. Chemical benefitting from a low background conductivity corre-
suppression is based on salts of weakly dissociated acids sponding to that of hydroxide eluents. Moreover, the
(e.g., NaHCO3 / Na2CO3), which produce carbonic acid interference by the carbonate peak during the quantita-
subsequent to cation exchange. The chemical suppres- tion of analyte ions is completely eliminated.
sion improves the sensitivity by a factor of 2 to 5.
Additionally, sequential suppression improves detection
Sequential suppression limits and produces a remarkably smaller injection peak,
Sequential suppression combines chemical suppression which in turn improves the determination of the fast-
with Metrohm CO2 Suppression (MCS). «MCS» removes eluting ions such as fluoride.
any carbonate and the CO2 that is produced by the sup-
Separation column Metrosep A Supp 5 - 100/4.0
Eluent 3.2 mmol/L Na2CO3/1.0 mmol/L NaHCO3
Flow rate 0.4 mL/min
Nr. Ion Conc. (mg/L)
1 Injection peak –
2 Fluoride 0.04
3 Chloride 7.79
4 Carbonate –
5 Bromide 0.004
6 Nitrate 7.82
7 Sulfate 5.20
Drinking water of Herisau (Switzerland): comparison of chemical (black) and sequential suppression (red)
«MSM II», «MSM-HC» and «MSM-LC»
With the chemical suppressors «MSM II», «MSM-HC» and
«MSM-LC» you can choose exactly the right suppressor
for your application. The «MSM II» is our standard supp-
ressor. The «MSM-HC» was developed for gradient app-
lications, but can also be used for isocratic applications
with columns with very high capacity. The low capa-
city «MSM-LC» was developed to be used with 2 mm
columns. The very low noise of less than 0.2 nS/cm for
all three suppressors guarantees an extremely high sensi-
tivity of the 850 Professional IC system. The robustness
and resistance against solvents and pressure allows
Metrohm to grant a unique 10-year warranty for these
suppressors.

11. 11
Reproducibility of suppression
The state-of-the-art tri-chamber suppressor technology The chromatograms shown below demonstrate the
provides a fresh suppressor chamber for each measure- excellent reproducibility of the measurements with the
ment. The complete regeneration of the chamber after Metrohm Suppressor Module:
each sample ensures highly efficient cation exchange –
today, tomorrow and even after years of continuous
operation.
1
2
3 4 5 7
6
30 injections, separation of the standard anions on the Metrosep A Supp 5 - 100/4.0, eluent 3.2 mmol/L Na2CO3/1.0 mmol/L NaHCO3,
flow 0.7 mL/min, loop 20 μL, 45 °C, sequential suppression
1 fluoride, 2 chloride, 3 nitrite, 4 bromide, 5 nitrate, 6 phosphate, 7 sulfate
Ion Fluoride Chloride Nitrite Bromide Nitrate Phosphate Sulfate
Concentration in mg/L 0.25 0.25 0.25 0.25 0.25 0.25 0.25
Relative standard deviation
0.17 0.16 0.38 0.31 0.18 0.46 0.25
in % (n = 30)

12. Automation
12 Automation in ion chromatography not only ensures
optimal use of the working hours but also improves the
reproducibility of the results. There is no more reason to
waste time on routine tasks such as manual sample in-
troduction or sample preparation. The sample changer
takes over all these functions. We offer you five different
sample changers: The 858 Professional Sample Processor,
the 863 Compact IC Autosampler, the 889 IC Sample
Center, the 814 USB Sample Processor and the 815
Robotic USB Sample Processor XL.
858 Professional Sample Processor – the perfect
match for the 850 Professional IC
The 858 Professional Sample Processor is more than a
simple sample changer. Equipped with pumps, injection
valve and Dosinos, it can be an integral part of Inline
Sample Preparation and Liquid Handling. More than 30
different sample racks are automatically recognized,
allowing the use of sample vessels that are different in
shape and volume. The standard version of the 858 Pro-
fessional Sample Processor accommodates 148 samples.
The 858 Professional Sample Processor can access up to
999 sample positions. It is also possible to use an external
position for performing tasks such as dilutions or rinsing
the needle.
The 858 Professional Sample Processor handles sample
volumes ranging from 500 μL to 500 mL. Sample transfer
is carried out by a peristaltic pump or a Dosino. Depend-
ing on the version of the 858 Professional Sample Pro-
cessor, an additional six-port injection valve is available
for sample preparation.

13. Metrohm Inline Sample Preparation (MISP)
Crystal clear, clinically pure, no bacteria and no particles: the quality of the results and drastically reducing costs. In
13
this would be an ideal sample for ion chromatography. these systems, sample preparation is integrated between
Unfortunately, apart from the ions to be determined, the the sample changer and the IC system.
samples often contain large amounts of interfering sub-
stances that make the analysis difficult if not impossible. Combined with the 858 Professional Sample Processor,
the 850 Professional IC offers a variety of fully automated
Critical samples such as milk, chocolate, caustic soda so- inline sample preparation steps such as Ultrafiltration,
lutions, biodiesel or strongly loaded waste waters require Dialysis, Preconcentration, Matrix Elimination, Neutrali-
sample preparation before they can be analyzed by IC. zation, Inline Calibration, intelligent Partial Loop Injection
However, manual sample preparation is time-consuming Technique and Sample Dilution.
and in many cases results in poor reproducibility, inaccu-
rate results and high costs. Metrohm’s powerful MagIC NetTM chromatography soft-
ware further expands the application range and provides
With Metrohm Inline Sample Preparation «MISP», many the ability to make logical decisions such as applying the
of these steps can be automated, significantly increasing automatically calculated dilution factors.
Metrohm Inline Sample Preparation (MISP): These techniques are the key to complete
automation of your analyses. Samples are introduced by means of a Sample Processor. Sub-
sequently, they are subjected to one of Metrohm’s Inline Sample Preparation techniques.
Finally, they are directly injected into an ion chromatograph. This fully automated sequence
is the common principle of all MISP techniques.

14. 14
ProfIC – automated Professional IC systems
Be it the determination of anions at high sample through- • Routine analysis of particle-containing samples
put in analytical service labs or the detection of cations (ProfIC 2)
in ultratrace levels as required in nuclear power plants – • Trace determination of anions in complex matrices
the ProfIC systems offer custom solutions for any IC (ProfIC 9) and
application. The website www.professional-ic.com • Parallel and independent determination of anions and
describes more than 20 different system. cations with intelligent Partial Loop Injection Technique
(ProfIC 15)
Combined with the analytical separation column and the
software, Metrohm ProfIC systems will solve even the For additional information please consult your Metrohm
most complex application problems. The three systems distributor or the Metrohm website.
presented here as examples perform the following tasks:

15. 15

16. «ProfIC 2» – Professional IC system with Ultrafiltration
16 Professional IC system for the fully automatic determina-
tion of anions or cations or both with Metrohm Inline
The ultrafiltration cell is mounted directly on the 858
Professional Sample Processor. The sample is continuously
Ultrafiltration. «ProfIC 2» safely masters all routine tasks delivered at a high flow rate. This delays the formation of
in ion chromatography. It is easy to use and extremely a filter cake and increases the working life of the mem-
reliable. The system’s components guarantee very high brane. Crossover is kept below 0.1%. Numerous sample
sensitivity and reproducible results. Particular attention racks for volumes 0.5...500 mL are available for the 858
has been given to long service intervals; these can be Professional Sample Processor. Ultrafiltration requires at
monitored by the intelligent MagIC NetTM software. least 5 mL of sample. «ProfIC 2» features intelligent sys-
tem components such as iPump and iDetector and acco-
«ProfIC 2» is equipped with Metrohm Inline Ultrafiltration, modates up to three iColumns.
which reliably removes particles from the sample. This
significantly increases the working life of the column. The The anion system is additionally equipped with sequen-
ultrafiltration cell is equipped with a membrane filter with tial suppression. This unique combination of chemical and
a pore size of 0.2 μm as standard and is suitable for downstream CO2 suppression allows to achieve very low
samples with a light to medium particle load. Inline Ultra- detection limits. The flexibility of the carbonate eluent is
filtration works fully automatically saving, for example, complemented by the low background conductivity.
the time-consuming and expensive use of syringe filters.
The «ProfIC 2» system is your reliable partner, both in
routine operation and in R&D.
Applications
• Determination of cations or anions or combined
determination of anions and cations
• Routine applications
• Analysis of samples containing interfering particles,
algae or bacteria, for example:
- Drinking water
- Process water
- Waste water
- Extracts
- Digestion solutions
- Diluted fruit and vegetable juice

17. 17
Flowsheet ProfIC 2 Anion
Schematic of ultrafiltration cell
ProfIC 2 Anion

18. «ProfIC 9» – Professional IC system for trace analysis
with Inline Calibration, Sample Preconcentration and
Matrix Elimination
18
Professional IC system for ultratrace analysis of anions or Calibration and calculation of the results as a function of
cations in complex matrices. «ProfIC 9» with Metrohm preconcentration volume is also carried out by the MagIC
Inline Sample Preconcentration and Matrix Elimination NetTM software. Even if complex procedures are involved,
allows chromatography unaffected by matrix influences operating the system remains perfectly easy.
and guarantees that the analytical column has a long
working life. Metrohm Inline Calibration permits very low The anion system is additionally equipped with sequen-
concentrations – in the ppt range (ng/L) – to be reliably tial suppression. Very high sensitivity is achieved by this
calibrated using a single standard of higher concentra- unique combination of chemical and downstream CO2
tion – in the ppb range (μg/L). suppression. The flexibility of the carbonate eluent is
complemented by the low background conductivity.
The sample is transferred to the preconcentration col- Elimination of the carbonate interference is a particular
umn fully automatically and with high precision by the benefit when using the preconcentration technique.
intelligent 800 Dosino. The anions or cations are retained.
The matrix can be removed in a rinsing step. The clean The 858 Professional Sample Processor provides for
sample is then transferred to the IC system. sample delivery. Numerous sample racks for volumes
0.5...500 mL are available. Typical preconcentration
The 850 Professional IC – Prep 2 is equipped with an volumes are between 0.5 and 100 mL.
additional valve for liquid handling. The peristaltic pump
TM
transfers the standard. The intelligent MagIC Net soft-
ware controls and monitors the system.
Applications
• Ultratrace analysis for anions and cations in
- Nuclear power plants
- Conventional power plants
- Semiconductor industry
• Trace analysis in organic solvents
• Quality control of fine chemicals

19. 19
Flowsheet ProfIC 9 Anion
ProfIC 9 Anion

20. «ProfIC 15» – Professional IC system for intelligent
Partial Loop Injection Technique
20 Professional IC system for the fully automated determina-
tion of anions, cations or anions and cations with Metrohm
The anion system is equipped with sequential suppres-
sion. The unique combination of chemical and down-
intelligent Partial Loop Injection Technique «MiPT». stream CO2 suppression results in very low detection
limits and allows to benefit from the flexibility of carbon-
Metrohm intelligent Partial Loop Injection Technique allows ate eluents and a low background conductivity corres-
the injection of variable sample volumes. This enables the ponding to that of hydroxide eluents.
injection of concentrated samples without previous dilu-
tion as well as multipoint calibration using a single stand- Sample transfer is carried out by the 800 Dosino. The
ard solution. «ProfIC 15» safely masters all routine tasks high-precision liquid handling enables simple and highly
in ion chromatography. reproducible Partial Loop Injections. This translates into
extremely accurate results and an excellent linearity. An
With this system, samples of widely different concentra- automated calibration covering a concentration ratio of
tions such as ultrapure water and drinking water can 1:10’000 can easily be carried out with just one standard.
be injected. «MiPT» ensures that the injected volume is
appropriate to the sample concentration. The efficient Numerous sample racks for volumes 0.5...500 mL are
rinsing procedure ensures that the carryover from sample available for the 858 Professional Sample Processor. Due
to sample is practically zero. The system is easy to operate to its flexibility, the «ProfIC 15» system is your reliable
and highly reliable. partner, both in routine operation and in R&D.
The system components guarantee very high sensitivity
and reproducibility of the results. Particular attention has
been given to long service intervals, which can be moni-
tored by the MagIC NetTM software.
Applikations
• Determination of anions, cations or combined
determination of anions and cations
• Routine applications
• R&D
• Trace analysis

21. 21
Flowsheet ProfIC 15 AnCat – the ideal system for the parallel analysis of anions and cations
ProfIC 15 AnCat

22. 872 Extension Module
22 The 872 Extension Modules enhance the capabilities of
the 850 Professional IC family.
872 Extension Module IC Pump
The 872 Extension Module IC Pump combines an IC high-
pressure pump «iPump» with an eluent degasser, a purge
The flexibility of the 850 Professional IC allows to tailor valve, an inline filter and a pulsation absorber.
the system to the application according to your needs.
Determination of anions and cations in parallel for one With the 872 Extension Module IC Pump, an isocratic
application and a quaternary gradient for another appli- Professional IC system can be expanded up to a quater-
cation are all simple tasks. nary high pressure gradient system.
Up to three 872 Extension Modules can be connected to 872 Extension Module Sample Prep
an 850 Professional IC instrument. The 872 Extension The 872 Extension Module Sample Prep comprises a
Modules are controlled by the user-friendly MagIC NetTM dual-channel peristaltic pump for transferring any type of
software, whose intelligence and ease of method con- liquid in the low-pressure range and a six-port injection
figuration greatly contribute to the flexibility of the over- valve that can be used both in the high-pressure and in
all system. the low-pressure range of the Professional IC system.
872 Extension Module Liquid Handling The 872 Extension Module Sample Prep expands the
The 872 Extension Module Liquid Handling features a possibilities of Inline Sample Preparation and Liquid Hand-
dual channel peristaltic pump for transferring all kinds of ling. Additional flexibility results from implementing column
liquids in the low-pressure range, a six-port injection valve selection systems, cutting techniques or multidimensional
and a ten-port selection valve. IC applications.
The 872 Extension Module Liquid Handling extends the
capabilities of Inline Sample Preparation and Liquid Hand-
ling thus extending the field of possible applications. For
example, the 872 Extension Module Liquid Handling can
be used to mix solutions, set the pH value of a sample or
carry out pre-column derivatization reactions.
Moreover, the ten-port valve can be used as a selection
valve for the automated supply of all kinds of liquid samples.

23. 23
872 Extension Module IC Module
The 872 Extension Module IC Module enables the instal- Toghether with one of the mentioned suppressor rotors,
lation of an additional IC high-pressure pump «iPump» the 872 Extension Module Suppression enables the ins-
with eluent degasser, purge valve, inline filter, pulsation tallation of an additional chemical suppressor in an 850
absorber and six-port injection valve in an 850 Professional Professional IC system. Thus, systems with two chemically
IC system. suppressed analytical channels become feasible.
Due to the 872 Extension Moudle IC Module, the 850 The 872 Extension Module Suppression can also be
Professional IC can be equipped with an additional analy- equipped with a Sample Preparation Module «SPM»-rotor
tical channel. Thus, applications like parallel analysis of permitting the combination of Inline Neutralizations with
anions and cations using a low pressure gradient or Inline various configurations of 850 Systems.
Neutralization become feasible. Moreover, an additional
analytical channel equipped with an alternative detector, 872 Extension Module Suppression – MCS
e.g., a UV/VIS detector or an amperormetric detector, Besides a dual-channel persistaltic pump and a Metrohm
becomes also possible. Suppressor Module, the 872 Extension Module Supp-
ression – MCS features a CO2 Suppressor «MCS». Any of
872 Extension Module Supperssion the three suppressor rotors «MSM II», «MSM-HC» or
The 872 Extension Module Suppression is equipped with a «MSM-LC» may be chosen, depending on the requirements.
dual-channel peristaltic pump and a Metrohm Suppressor
Module. Any of the three suppressor rotors «MSM II», The 872 Extension Module Suppression – MCS enables
«MSM-HC» or «MSM-LC» can be chosen, depending on the installation of an additional sequential suppressor in
the requirements. an 850 Professional IC system. Thus, systems with two
complete anion channels can be configured.

24. 24
Technical information
General Professional ion chromatography system
• Compact modular system
• Intelligent system components
• Integral Metrohm Inline Sample Preparation «MISP»
• Metal-free flow path
• 3-year warranty
Intelligent system Intelligent technology is incorporated in the following system components,
components among others:
• iPump • iDetector
• iColumn • 800 Dosino
Metrohm Inline Sample The following optional components can be integrated:
Preparation «MISP» • Ultrafiltration • Neutralization
• Dialysis • Matrix Elimination
• Dilution • Calibration
• Preconcentration • Partial Loop Injection Technique
Eluent and sample Organic modifier 0...100% (no PFCs [perfluoro carbon compounds])
degassing Material Teflon AFTM
High-pressure pump Serial dual-piston pump with two valves and flow-range-optimized intelligent pump
heads
Flow rate 0.001...20 mL/min
Reproducibility <0.1% deviation from the set value
Pulsation <1% (typically)
Injection valve Injection volume:
Internal loop 0.25, 1 μL
External sample loop 1.5, 5, 10, 20, 100, 250, 1000 μL
Column thermostat Temperature range 0...80 °C (ambient temperature -20...+50 °C)
Stability <0.05 °C
Suppressors «MSM II», «MSM-HC» or «MSM-LC» Metrohm Suppressor Modules for chemical
suppression
Type «Micro Packed Bed» suppressor
Design 3 cartridges in a rotor
Regeneration 100 mmol/L H2SO4
Rinsing demineralized water
Transport of solutions Peristaltic pump or 800 Dosino
Organic modifier 0...100%
Warranty 10 years
«MCS» Metrohm CO2 Suppressor
Type CO2 removal with Teflon AFTM technology
Organic modifier 0...100% (no PFCs [perfluoro carbon compounds])

25. Conductivity detector Conductivity detector
Measuring principle
Intelligent high-performance conductivity detector
DSP – Digital Signal Processing
25
Measuring range 0...15 000 μS/cm – without range switching
Max. back pressure 5 MPa
Temperature 20...50 °C in steps of 5 °C
Temperature stability <0.001 °C
Cell volume 0.8 μL
Cell constant 16.7/cm (nominal), calibrated value is stored in
iDetector, can be recalibrated
Measuring frequency 10 Hz
Resolution 4.7 pS/cm
Electronic noise <0.1 nS/cm (at 1 μS/cm)
Baseline noise <0.2 nS/cm (e.g. A Supp 5, standard conditions)
Peristaltic pumps Speed 0...42 rpm in steps of 6 rpm
Direction clockwise and counter-clockwise
Gradients Type high-pressure: binary, ternary, quaternary
low-pressure: binary, ternary
Dosino: binary, ternary, quaternary, quinary
Form step, linear, convex*, concave*
(*...for high- and low-pressure gradients)
Professional Sample Processor
Racks Automatic sample rack recognition (individual adaptations of the sample rack
to accommodate specific vessel forms and sizes are possible)
Sample volume 0.5...500 mL (standard volume: 11 mL)
Positions 999 rack positions and four external positions are accessible
Control Metrodata MagIC NetTM
Connections 850 Professional IC 858 Professional Sample Processor
Leak sensor 1 USB upstream 3 (hub)
Detectors 2 USB downstream 1 (PC)
USB upstream 2 (hub) MSB (Metrohm Serial Bus) 3
USB downstream 1 (PC) Membrane pumps 2
MSB (Metrohm Serial Bus) 2 Swing Head 1
Connection of peripheral instruments: 858 Professional Sample Processor via USB;
800 Dosino, 801 Magnetic Stirrer, 6.2148.010 Remote Box, etc. via MSB
Dimensions in mm (W/H/D) 850 Professional IC 858 Professional Sample Processor
365/642/380 280/730/500
872 Extension Module
365/131/380

26. Ordering information
26 ProfIC systems
Professional IC system for automated ion chromatography
(ProfIC 1 – Anion, ProfIC 1 – Cation and ProfIC 1 – AnCat)
Professional IC system with Inline Ultrafiltration
(ProfIC 2 – Anion, ProfIC 2 – Cation and ProfIC 2 – AnCat)
Professional IC system with Inline Dialysis
(ProfIC 3 – Anion and ProfIC 3 – Cation)
Professional IC system with Inline Dilution
(ProfIC 4 – Anion and ProfIC 4 – Cation)
Professional IC system with Inline Preconcentration
(ProfIC 5 – Anion and ProfIC 5 – Cation)
Professional IC system with Inline Dilution and Ultrafiltration
(ProfIC 6 – Anion and ProfIC 6 – Cation)
Professional IC system with Inline Dilution and Dialysis
(ProfIC 7 – Anion and ProfIC 7 – Cation)
Professional IC system with Inline Preconcentration and Matrix Elimination
(ProfIC 8 – Anion and ProfIC 8 – Cation)
Professional IC system for trace analysis with Inline Calibration, Preconcentration and Matrix Elimination
(ProfIC 9 – Anion und ProfIC 9 – Cation)
Professional IC system with Inline Preconcentration, Matrix Elimination and Neutralization
(ProfIC 10 – Anion)
Professional IC system for trace analysis with Inline Calibration, Preconcentration, Matrix Elimination and Neutralization
(ProfIC 11 – Anion)
Professional IC Gradient System
(ProfIC 12 – Anion)
Professional IC system for intelligent Partial Loop Injection Technique
(ProfIC 15 – Anion, ProfIC 15 – Cation and ProfIC 15 – AnCat)
Software MagIC NetTM
6.6059.222 MagIC NetTM 2.2 Professional
6.6059.208 MagIC NetTM 2.X Professional upgrade to Multi – 3 licenses
6.6059.223 MagIC NetTM 2.2 Multi – 3 licenses
6.6059.001 MagIC NetTM Multi – 1 additional license
6.6059.002 MagIC NetTM Multi – 5 additional licenses
6.6059.003 MagIC NetTM Multi – 10 additional licenses
850 Professional IC instruments
2.850.1010 850 Professional IC Cation
2.850.1030 850 Professional IC Cation – Prep 1
2.850.1050 850 Professional IC Cation – Prep 2
2.850.1210 850 Professional IC Cation – LP Gradient
2.850.1220 850 Professional IC Cation – Gradient
2.850.2010 850 Professional IC Anion*
2.850.2030 850 Professional IC Anion – MCS*
2.850.2050 850 Professional IC Anion – MSM-HC*
2.850.2070 850 Professional IC Anion – MSM-HC – MCS*
2.850.2110 850 Professional IC Anion – MCS – Prep 1*
2.850.2120 850 Professional IC Anion – MSM-HC – MCS – Prep 1*
2.850.2140 850 Professional IC Anion – MSM-HC – MCS – Prep 2*
2.850.2150 850 Professional IC Anion – MCS – Prep 2*
2.850.2180 850 Professional IC Anion – MSM-HC – MCS – Prep 3*
2.850.2190 850 Professional IC Anion – MCS – Prep 3*
2.850.2210 850 Professional IC Anion – MCS – LP Gradient*
2.850.2220 850 Professional IC Anion – MCS – Gradient*
2.850.2230 850 Professional IC Anion – MSM-HC – MCS – LP Gradient*

27. 2.850.2240
2.850.2250
850 Professional IC Anion – MSM-HC – MCS – Gradient*
850 Professional IC Anion – MSM-HC – LP Gradient*
27
2.850.2260 850 Professional IC Anion – MSM-HC – Gradient*
2.850.3000 850 Professional IC AnCat – non-suppressed
2.850.3010 850 Professional IC AnCat
2.850.3030 850 Professional IC AnCat – MCS
2.850.3040 850 Professional IC AnCat – MSM-HC – MCS
* ... 850 Professional IC instruments for anion analysis can also be used for cation analyis.
872 Extension Module
2.872.0010 872 Extension Module IC Pump
2.872.0030 872 Extension Module IC Module
2.872.0050 872 Extension Module Sample Prep
2.872.0060 872 Extension Module Liquid Handling
2.872.0110 872 Extension Module Suppression
2.872.0120 872 Extension Module Suppression – MCS
850 Professional IC – detectors (to be ordered separately)
2.850.9010 850 Professional IC Detector «iDetector»
2.887.0010 887 Professional UV/VIS Detector
850 Professional IC – accessories
6.5330.000 IC equipment for Dialysis
6.5330.010 IC equipment for Ultrafiltration
6.5330.020 IC equipment for Sample Dilution
6.5330.040 IC equipment for Liquid Handling with the Dosino
6.5330.050 IC equipment for Dosino Gradient
6.5334.000 4-port-stator and 0.25-μL-rotor equipment
6.5334.010 4-port-stator and 1.0-μL-rotor equipment
Automation
2.858.0010 858 Professional Sample Processor
2.858.0020 858 Professional Sample Processor – Pump
2.858.0030 858 Professional Sample Processor – Pump – Injector
2.863.0010 863 Compact IC Autosampler
2.889.0010 889 IC Sample Center
2.889.0020 889 IC Sample Center – cool
858 Professional Sample Processor – accessories
6.2041.440 Standard sample rack 148 x 11 mL + 3 x 300 mL
6.2041.760 Sample rack 54 x 11 mL + 1 x 300 mL
6.2041.390 Sample rack 16 x 120 mL
6.2041.480 Sample rack 159 x 2 mL + 3 x 300 mL
6.2743.050 PP sample vessels (11 mL); 2000 pieces
6.2743.040 PP sample vessels (2.5 mL); 2000 pieces
6.2743.070 PP stopper with perforation for sealing the sample vessels; 2000 pieces
6.5330.030 IC equipment rinsing station for 858 Sample Processor
Liquid Handling
2.800.0010 800 Dosino
2.801.0010 801 Magnetic Stirrer
2.849.1030 849 Level Control for Inline Eluent Preparation
6.3032.210 Dosing Unit 10 mL
6.2070.000 Footprint Extension to 801 Stirrer

28. Subject to change
Layout by Ecknauer+Schoch ASW, printed in Switzerland by Metrohm AG, Herisau
8.850.5006EN – 2010-05
www.professional-ic.com