7. STENT
A mesh 'tube'
Inserted into a natural passage/conduit in the body
Treats narrow or weak arteries
8. Stents usually are made of metal mesh, but
sometimes they're made of fabric
Fabric stents, also called stent grafts, are used in
larger arteries
Some stents are coated with medicine that is slowly
and continuously released into the artery
9.
10.
11. Figure A shows the location of the heart and coronary arteries
Figure B shows the deflated balloon catheter and closed stent inserted into
the narrow coronary artery
The inset image shows a cross-section of the artery with the inserted balloon
catheter and closed stent
In figure C, the balloon is inflated, expanding the stent and compressing the
plaque against the artery wall
Figure D shows the stent-widened artery. The inset image shows a crosssection of the compressed plaque and stent-widened artery
12. RISKS RELaTED TO STENTS
Blood clot at the stent site
Blood clots can cause a heart attack, stroke, or other
serious problems
Stents coated with medicine may raise the risk of
dangerous blood clots
14. STRAIN TAKES TOLL ON
HEART
Hypertension : three times higher in urban citizens
than their rural counterparts
9% of population in the age bracket of 40-70 undergo
angioplasty every year
BMS is the most popular choice
Several post surgery complications are involved
35. COMPONENT
S
PLLA (Poly-L-Lactic Acid) Backbone
PDLLA (Poly-D, L-Lactic Acid) Coating
Drugs coated on it include :
VEGF (Vascular Endothelial Growth Factor) to
promote healing
ASPIRIN to reduce the ability of blood to clot
easily
STATIN to help in reabsorbing cholesterol
36.
37. Both the backbone and coating will degrade to
lactic acid (Kreb’s cycle)
Drugs coated on it are to serve their respective
function
Entire stent should dissolve in 2-3 yrs without
any side effects
40. StrategieS
Spreading awareness
Contacting doctors & MRs
One on one presentations
Hiring professionals for personal selling
Taking feedback
46. aSSUMPtiON
S
Pre-supposed approval by FDA
Rs. 90,000 : average cost of a stent in India
Based on historical precedence, our price 2.5 lakh at
initial entry
20% hurdle rate
Total cost inclusive of trials : 8 crores
Profit Margin of 65%