Cancer, Alzheimers, diabetes are diseases of lifestyle. Learn how the begin in the body and what you can do to protect yourself.

1. ©
1

2. WHO AM I?
I am a Medical Herbalist, trained in the UK, in
integrated medicine in clinics, hospitals and
university environments
I treat cancer, pre cancerous and chronic auto immune
conditions such as Diabetes, Alzheimer's, thyroid
and women’s problems in a (w) holistic protocol, on
a science evidenced basis with plant drugs
Disclosure - No commercial ties
©
2

3. WHAT DO I DO?
I ASSESS THE CONDITION ( DIAGNOSE ) , EXAMINE THE PATIENT,
TAKE A CASE HISTORY, COMPOUND ( PRESCRIBE ); IDENTIFY THE
CAUSE OF THE PROBLEM WITH THE OBJECTIVE OF RESOLVING IT
WITH PLANT DRUGS ON AN EVIDENCED BASED BASIS.
©
3

4. WHY ARE WE TALKING ABOUT CANCER,
DIABETES TYPE II AND ALZHEIMERS IN ONE
SENTENCE?
BECAUSE:
©
4

5. OVER VIEW - CANCER, ALZHEIMER'S, DIABETES
•
CANCER IS A CHRONIC ENDOCRINE METABOLIC DISEASE
IT IS A DISEASE OF ABERRANT CELL SIGNALLING AND
PROLIFERATION
•
DIABETES IS A CHRONIC ENDOCRINE METABOLIC DISEASE
IT IS A DISEASE OF ABERRANT CELL SIGNALLING AND CELL
DEATH
•
ALZHEIMERS IS A CHRONIC ENDORCINE METABOLIC
DISEASE IS A DISEASE OF ABERRANT CELL SIGNALLING AND
PROLIFERATION
©
5

6. THEY ARE ALL CHRONIC DISEASES
Chronic diseases are those medical issues people ‘live with’ in the defined
medical model and do not cause immediate death
The current medical model is not designed for chronic diseases
Nearly all chronic disease are diseases of excess/lifestyle only around 5%
are genetic
Life expectancy has grown in 20 yrs. from 72 to 84 in 20 years this means
that the consequences of excess will become more and more apparent
©
6

7. ALL ARE METABOLIC ENDOCRINE DISEASES
WHAT IS THIS?
It means that this triad of disease arise from an impaired functioning of all
the physical and chemical changes that take place in the body to
enable bodily growth & function which is determined in large part by the
endocrine glands
This means all have a slow onset which is reversible at many stages
•
Glucose disturbance appears years before a diabetes diagnosis. European Association
for the Study of Diabetes (EASD) 47th Annual Meeting: Abstract 335.September 13, 2011.
THIS MEANS YOU ARE WHAT YOU EAT!
This means all involve the brain
©
7

8. THE MICROBIOME
Dietary Deficiencies +
Viruses}
Bacteria}
combine to create most chronic auto immune
diseases
cancer, Alzheimer's, Parkinson's, MS, arthritis,
diabetes
©
8

9. MICROBIOME
The Microbiome is the most exciting development in the
last 50 yrs. in medicine
What you eat is totally under your control and preventable
medicine
There will never be a drug for bacteria & viruses in the gut
as they mutate
Most plants have anti bacterial and anti viral properties!
The microbiome and cancer.Schwabe RF, Jobin C.Nat Rev Cancer. 2013 Nov;13(11):800-12
Assessing the human gut microbiota in metabolic diseases. Karlsson F, et al Diabetes. 2013 Oct;62(10):3341-9
Extragastric diseases and Helicobacter pylori. Roubaud Baudron C, et al Helicobacter. 2013 Sep;18 Suppl 1:44-51.
Alzheimer's disease and the microbiome. Bhattacharjee S, Lukiw WJ. Front Cell Neurosci. 2013 Sep 17;7:153. doi:
10.3389/fncel.2013.00153.
©
9

10. ALL INVOLVE DYSREGULATION OF THE THYROID
– HPA/AXIS
The Thyroid plays the music written by the Hypothalamus in the brain
The signalling hormone TSH from the brain gets converted to T4 and T3 in
the gland. These hormones act on cells in all bodily tissues and can
alter gene products
Subclinical hypothyroidism is endemic in Ontario (Cancer in Ontario Overview
: A statistical report 2011)
The hormones regulate protein, carbohydrate and fat metabolism – in other
words all functions and diseases within the body normally described as
endocrine metabolism.
Another way is to say it regulates all fuel ( glucose ), Cells ( fats ) and DNA
(protein)
©
10

11. COMMON PATHOLOGIES
Cancer, Alzheimer’s and Diabetes all start via a common pathway of
nutritional deficiencies or excess leading to a process called
inflammation.
More women than men; 40-60yrs; western world; obesity
UBIQUITIN Could dysregulation of UPS be a common underlying
mechanism for cancer and neurodegeneration? . Jara JH, et al. Davee
Department of Neurology and Clinical Neurological Sciences, Feinberg School of
Medicine, Northwestern University, Chicago, IL 60611, USA.
Mitochondrial sirtuins as therapeutic targets for age-related disorders.Shih J, Donmez G.Genes Cancer. 2013 Mar;4(3-4):91-6. doi:
10.1177/1947601912474931.
Common pathologies for neurodegenerative disorders Brain Nerve. 2012 Jun;64(6):675-9.
Are neurodegenerative diseases "protein cancers"?. Hasegawa M.Depart of Neuropathology and Cell Biology, Tokyo Metropolitan Institute of Medical
Science, Japan.
Autophagy Dysfunction & its Link to Alzheimer's Disease & Diabetes Mellitus. Wilson CM, et al CNS Neurol Disord Drug Targets. 2013 Sep 18
[Diabetes type 2 and Alzheimer disease - one or two diseases? Mechanisms of association]. Marszałek M. et al 2013 Jul 23;67:653-71
©
11

12. MORTALITY
Top causes of death Cancer, diabetes and Alzheimer's is projected by 2050
to be the third
In older people > 65 yrs. 2 of these diseases may be present at one time
The relative risks imparted by diabetes are greatest (about twofold or
higher) for cancers of the liver, pancreas, and endometrium, and lesser
(about 1.2–1.5 fold) for cancers of the colon and rectum, breast, and
bladder. Other cancers (e.g., lung) do not appear to be associated with
an increased risk in diabetes, and the evidence for others (e.g., kidney,
non-Hodgkin ) is inconclusive Diabetes Care 2010 July (33) 7 1674-1685
©
12

13. ALL INVOLVE NEUROLOGICAL PATHWAYS
The invasion of the neurological pathways start in the gut – the results are
expressed differently in each disease
Brain Fog
β-amyloid is transmitted via neuronal connections along axonal
membranes. Song HL, Shim S, Kim DH, Won SH, Joo S, Kim S, Jeon
NL, Yoon SY. Ann Neurol. 2013 Oct 2. doi: 10.1002/ana.24029.
Amyloid is also found deposited in the islet cells of the Pancreas
It is also found in cancer – eg brain and lymphomas, prostate cancers etc.
©
13

14. SURGERY & DRUGS
ALL 3 CONDITIONS ARE OVER TREATED with poor
outcomes
Diabetes and Alzheimer’s are untreatable by surgery except
when side effects become extreme - gangrene
Cancer is upregulated by surgery – Peeters et al 2008
ELI JONES 1895
Avoid PET, CT scans in cancer
Do Not perform PSA testing for prostate cancer with men no
symptoms of disease who are expected to live < 10yrs.
J Clin Oncol Oct 29 2013
©
14

15. DRUGS
•
Alzheimers – Aricept claims to reduce progression only.
CMAJ. 2013 Sep 23. Efficacy and safety of cognitive enhancers for patients with
mild cognitive impairment: a systematic review and meta-analysis. Tricco AC
et al
•
Diabetes – Metformin commonly but failure to address B12 deficiency
other commonly used drugs actually have been shown to make the
collapse of the pancreas worse
Increased risk of cognitive impairment in patients with diabetes is associated
with metformin. Moore EM, et al.Diabetes Care. 2013 Oct;36(10):2981-7.
•
Cancer – those commonly used all have life threatening consequences
Avastin – recent publicity – failed to discuss the pharmacological issues
and consequences.
©
15

16. STATINS – DON’T!
Statins can cross the blood brain barrier and are responsible for fog brain
commonly described by patients. Potential underlying mechanisms for
statin side effects. Brain and Behaviour 15 My 2013
March 2012 the FDA announced that it was revising the labels of all statins
to warn that they can raise blood glucose and hemoglobin A1c levels.
updating the label of lovastatin to warn that a number of interacting
drugs can increase statin exposure up to 20-fold and trigger
rhabdomyolysis. revised label for lovastatin will include new
contraindications and dose limitations.
The Justification for the Use of Statins in Primary Prevention: An
Intervention Trial Evaluating Rosuvastatin (JUPITER) trial showed a 27%
increase in diabetes mellitus in patients taking rosuvastatin compared
to placebo.
Note - Ubiquitin
©
16

17. ALL 3 ARE REVERSIBLE AND PREVENTABLE
All progress as a long process of inflammation in the body
All take years of physiological change before they can be
diagnosed under the current conventional model
All involve high homocysteine levels ignored by current
models despite easy prevention
Plasma homocysteine, Alzheimer and cerebrovascular pathology: Hooshmand B, et al
Brain. 2013 Sep;136(Pt 9):2707-16.
©
17

18. CAUSES FOR ALL 3 – DIET DIET DIET
Copper
Bacteria
Lack of B vitamins
Lack of fresh vegetables and fruit
Excess of sugar and processed foods
Dietary fructose induces endotoxemia and hepatic injury in calorically controlled primates.Kavanagh
K et al JM.Am J Clin Nutr. 2013 Aug;98(2):349-57.
Functional foods and nutraceuticals as therapeutic tools for the treatment of diet-related diseases. Magrone T, et al. Can J Physiol Pharmacol. 2013
Jun;91(6):387-96. doi: 10.1139/cjpp-2012-0307
©
18

19. MED DIET
Association of Mediterranean Diet with Mild
Cognitive Impairment and Alzheimer's
Disease: A Systematic Review and MetaAnalysis. PROSPERO 2013
Singh B, Parsaik et alDepartment of Neurology, Department of Health Sciences Research, Mayo
Clinic, Rochester, MN, USA Department of Clinical Neuroscience, University of North Dakota
School of Medicine
Background/Objective: To conduct a systematic review of all studies to determine whether there is
an association between the Mediterranean diet (MeDi) and cognitive impairment. screened, five
studies met eligibility criteria. Higher adherence to the MeDi was associated with reduced risk of
had 33% less risk
MCI and AD. The subjects in the highest MeDi tertile
(adjusted HR = 0.67; 95% CI, 0.55-0.81; p < 0.0001) of cognitive impairment (MCI or AD) as
compared to the lowest MeDi score tertileprogressing from MCI to AD.
©
19

20. SUGAR IS WHITE SWEET AND DEADLY!*
The presence of sugar in processed foods has grown exponentially since
1900 – so has the diagnosis of Cancer – Diabetes - Alzheimers
Globally, sugar consumption has tripled in the past 50 years. But, it turns
out, the greatest threat to human health is one type of sugar in
particular: fructose.
In the US, per-capita consumption of fructose, a common food additive
there – mainly in the form of high-fructose corn syrup – has increased
more than 100-fold since 1970.
Processed foods lack key nutrients. 1tsp =
fruits
J.Physiol 2012 590:2485-2499 Gomez-Pinella see also Lustig / Yudkin*
©
20

21. DIET - SUGAR
Warburg in 1925 deduced quite correctly that:
“Cancer has only one prime cause. It is the replacement of normal oxygen
respiration of the body’s cells by anaerobic oxygen deficient cell
respiration”
Confirmed again in 2008 by another Nobel prize winner!
Ist calorie restriction to treat cancer randomised clinical trial approved by
Duke University Feb 2013
Use of Metformin endemic but this is not the answer! – Increases cognitive
impairment – Moore Diabetes Care 2013 Sept 5 – B12 issues not present
if gallega officinalis is used!
©
21

22. SUGAR
Grains translate to sugars in the body:
Sugar is inflammatory to the body ( inflammation being the key
pathological process in cancer, diabetes and Alzheimer's )
Sugar provides a better less hostile environment in the gut for bacteria and
viruses to grow and live ( bacteria and viruses part of the pathological
processes of cancer )
High circulating sugar levels impede the function of the brain, liver,
kidneys, pancreas and thyroid. The receptors leading to further
biochemical processes in the body are altered.
Obesity and other concomitant diseases
©
22

23. SUGAR & MORTALITY
THE INCREASE IN MORTALITY IN CANCER – DIABETES - ALZHEIMERS
HAS MIRRORED THE USE OF PROCESSED FOODS AND INCREASED
CONSUMPTION OF SUGAR
IN 1900 CANCER/DIABETES WAS NOT EVEN IN THE TOP 10 CAUSES OF
DEATH
TODAY IN NORTH AMERICA IT IS THE NUMBER ONE & TWO CAUSE OF
DEATH
Mortality by diet and physical activity (PA) in Women’s Healthy Eating and living Study
comparison group Pierce J et al J Oncol 25:2345 2007
CDC.ORG
©
23

24. BE ALIVE
AVOID PROCESSED FOODS
LOVE YOUR VEGGIES
INNOVATE AND EAT A WIDE RANGE OF FOOD STUFFS
Value moderation
ELIMINATE SUGAR FROM YOUR DIET
©
24

25. STRESS
Minimize
Stress stimulates the fear flight mechanisms and
upregulates physiological functions – like driving a car at
90mph all the time, in turn that ‘exhausts’ the adrenal
glands and inhibits proper metabolism
Hans Seyle – Canadian
GAS syndrome
©
25

26. EXERCISE
At least an hour a day is mandatory - our lifestyle has become
very sedentary but our bodies are not designed to be sedentary
Long-term treadmill exercise inhibits the progression of
Alzheimer's disease-like neuropathology in the hippocampus of
APP/PS1 transgenic mice. Liu HL, et al. Behav Brain Res. 2013
Aug 19;256C:261-272.
In cancer and diabetes exercise has shown consistently a long
term beneficial effect resulting in good prognosis
©
26

27. WHAT CAN I DO ABOUT? LOTS!!
There are many very effective herbal medicine protocols which
inhibit the development of cancer, diabetes, Alzheimer's
These plants have huge amounts of science about them.
Curcuma Longa – Turmeric is probably the best known
98 metabolic pathways affected – efficacy shown against 19
cancers, diabetes and Alzheimer's
“Most efficacious cancer drug is a plant” Prof. BB Aggarwal MD
Anderson Cancer centre & University of Texas
©
27

28. PLANTS & CANCER
Angiogenic and proliferative effect of the cytokine VEGF in Ehrlich ascites tumour cells in inhibited
by Glycyrrhiza glabra. Sheela ML et al Int Immunopharmacol 2006 Mar 6(3)494-8
Anti tumour properties of Boswellic acid against Ehrlick ascites cells bearing mouse
Agrawal SS et al Food Chem Toxicol 2011 Sept 49(9)
Cancer has 27 principal pathways for growth – I
have plants which block all those pathways
Garlic, Cat’s claw, Red Clover, Black Cohorsh, Yew, Poke, Chaga, Magnolia
Etc. etc. etc. etc. etc.
©
28

29. PLANTS AND DIABETES
Do plants mediate their anti-diabetic effects through anti-oxidant
and anti-apoptotic actions? an in vitro assay of 3 Indian
medicinal plants. Kalekar SA, et al. BMC Complement Altern Med. 2013 Oct
5;13(1):257.
Improved glycemic control and lipid profile in hyperlipidemic type
diabetic patients consuming Salvia officinalis L. leaf extract: a
randomize placebo. Controlled clinical trial. Kianbakht S, Dabaghian
FH. Complement Ther Med. 2013 Oct;21(5):441-6.
Evidence based herbal drug standardization approach in coping
with challenges of holistic management of diabetes: a dreadful
lifestyle disorder of 21st century. Et al .J Diabetes Metab Disord. 2013
Jul 4;12(1):35..
©
29

30. PLANTS & ALZHEIMERS
Effect of plant extracts on Alzheimer’s disease: An insight into therapeutic avenues Obulescu
M, et al J Neurosci Rural Pract 2011 Jan 2(1) 56-61
Berberine a potential multipotent natural product to combat Alzheimer’s disease Ji HF,et al
Molecules 2011 Aug 9 16 (8) 6732-40
Saffron in the treatment of patients with mild to moderate Alzheimer’s disease: 16 week trial
Akhondzaheh S et al.J Clin Pharm Ther 2010 Oct 35 (5) 581-8
Orally administrated cinnamon extract reduces beta amyloid oligomerization and corrects
cognitive impairment in Alzheimer’s Frydom-Marom A et al, Plos One 2011 Jan 28 6 (1) e
16564
Ginseng & Rosemary & Lemon Balm & CitrusPsychogeriatrics. 2009 Dec;9(4):173-9. doi:
10.1111/j.1479-8301.2009.00299.x.Effect of aromatherapy on patients with Alzheimer's
disease.Jimbo D, et al School of Health Science, Faculty of Medicine, Tottori University,
Japan.
J Neurol Neurosurg Psychiatry. 2003 Jul;74(7):863-6.Melissa officinalis extract double blind,
randomised, placebo controlled trial. Akhondzadeh S, et alRoozbeh Psychiatric Hospital,
Tehran University , Tehran, I
©
30

31. OTC - CAVEATS
Illegal to sell a medically efficacious dose
Most are not pharmaceutical grade
No evidence base / extrapolation claims
Contents /label/marketing claim
Unnecessary with a proper diet
No consideration of individual needs
Failure to address polysupplementation
©
31

32. EXAMPLE OF OTC ISSUES
DO NOT USE PROTEIN POWDER WHERE THERE
ARE SUGARS – AGAVE, STEVIA, SYNTHETIC
SWEETNERS,
Just because its ‘natural’ does not mean its good for you
Circulating insulin like growth factors and related binding proteins are selectively altered in
amyotrophic lateral sclerosis and multiple sclerosis. Growth Hormone & IGF research Vol 17
Issue 6 Dec 2007 Hosback et al
Vitamin A
©
32

33. BE SENSIBLE
PLEASE DO NOT SELF TREAT
THE PLANT DRUGS I USE ARE NOT AVAILABLE OVER THE COUNTER
IN SOME DISEASE USE OF OVER THE COUNTER SUPPLEMENTATION IS
HARMFUL.
PLEASE NOTE IT IS ADVISED, THAT ANY PLANTS MENTIONED IN THIS
TALK, ARE ONLY USED UNDER PROFESSIONAL GUIDANCE.
.A professional: will recognise all the issues within the body
Select herbs that will impact positively on these issues without causing
problems in order to co exist with orthodox drugs,
©
33

34. REFERENCES
Some of the references used have been shown in
the text but if you want a full list please email
me at
mrsmg@sympatico.ca
All references are available on Pubmed
©
34

35. FOUNDATION
I AM IN THE PROCESS OF ESTABLISHING A FOUNDATION TO GIVE
CANADIANS THE OPPORTUNITY TO HAVE THE EDUCATION I
RECEIVED TO BE ABLE TO TREAT PEOPLE WITH PLANT MEDICINE
WHICH IS DESIGNATED BY THE UN AS A ‘ HUMAN RIGHT ’
THERE IS CURRENTLY NO DEGREE COURSE AVAILABLE IN CANADA
NOR EDUCATION AT THE LEVEL I RECEIVED.
THE CONCEPT OF THE FOUNDATION IS TO PROVIDE THE FUNDS TO
ESTABLISH A DEGREE COURSE WITHIN AN EXISTING UNIVERSITY
ASSOCIATED WITH A HOSPITAL IN CANADA
THE FOUNDATION IS ALSO TO DEVELOP A RECPRICOCITY FOR TRAINING
WITH ST HILDA’S COLLEGE OXFORD FOR THOSE WISHING TO DO
HIGHER DEGREES SUCH AS AN MSC. ELINOR RHODE LIVES ON!
©
35

36. THANK YOU
Morwenna Given
MEDICAL HERBALIST
BA MA (Oxon) BSc m.OHA BHG AHG
RH
www.medicusherbis.com
©
36