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-FXS is a genetic syndrome that is the most widespread single-gene cause of autism and inherited cause of mental retardation. - It is associated with the expansion of the CGG trinucleotide repeat affecting the Fragile X mental retardation 1 (FMR1) gene on the X chromosome. - Resulting in a failure to express the fragile X mental retardation protein (FMRP). -FMRP is required for normal neural development. -Absence of FMRP leads to abnormalities in brain development and function.
FRAGILE X SYNDROME ( FXS ) an inherited cause of mental retardation.
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Fragile X syndrome causes mild to severe intellectual disability. It affects both males and females, but females usually have milder symptoms. Symptoms include delays in talking, anxiety and hyperactive behaviour. Some people have seizures. Physical features might include large ears, a long face, a prominent jaw and forehead and flat feet. Therapy can be used to treat learning disabilities. Medication may be used to treat anxiety and mood disorders.
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-FXS is a genetic syndrome that is the most widespread single-gene cause of autism and inherited cause of mental retardation. - It is associated with the expansion of the CGG trinucleotide repeat affecting the Fragile X mental retardation 1 (FMR1) gene on the X chromosome. - Resulting in a failure to express the fragile X mental retardation protein (FMRP). -FMRP is required for normal neural development. -Absence of FMRP leads to abnormalities in brain development and function.
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Fragile X syndrome causes mild to severe intellectual disability. It affects both males and females, but females usually have milder symptoms. Symptoms include delays in talking, anxiety and hyperactive behaviour. Some people have seizures. Physical features might include large ears, a long face, a prominent jaw and forehead and flat feet. Therapy can be used to treat learning disabilities. Medication may be used to treat anxiety and mood disorders.
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