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Update on diabetes 2010 ,[object Object]
High blood sugar
Energy/Fuel
Magic Numbers ,[object Object],[object Object],[object Object]
 
Where do we get sugar?
 
 
Symptoms - dilution
Why?
 
 
Damage to Cells
Genetics
Stressing the Pancreas
Inflammation
 
Complications
Other causes of Inflammation
Overall Risk ,[object Object],[object Object],[object Object],[object Object],[object Object]
Belly Fat
 
Prevalence ,[object Object],[object Object],[object Object]
Future? 36 million in 2025?
Prevention ,[object Object],[object Object],[object Object]
Medications ,[object Object],[object Object],[object Object],[object Object],[object Object]
Treatment
 
Insulin stimulation
Stimulate insulin right after eating
Reduce insulin resistance reduce glucose production by liver
Allow insulin to enter cells
Prevent the digestive system from absorbing insulin
Promote Incretins – keeps you blood sugar in a more normal range after eating
Injectable Medications
Insulin ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
 
Incretin Mimetics – GLP-1 ,[object Object],[object Object],[object Object],[object Object],[object Object]
 
 
Amylin/Symlin ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Insulin Pump
 
 
What else can we do?
For a transplant ,[object Object],[object Object],[object Object]
Not enough insulin producing cells ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Islet Cells
Transplanted Islets ,[object Object],[object Object],[object Object],[object Object]
Other problems ,[object Object],[object Object],[object Object],[object Object]
Artificial Pancreas?
What else can we do? ,[object Object],[object Object],[object Object],[object Object],[object Object]
Teach your children well… * A code you can live by * Teach them when you see  the truth Crosby, Stills Nash and Young, 1970 * Don’t let them stress their pancreas * Keep them moving

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Update on Diabetes 2010

Notas del editor

  1. From beta cell dysfunction
  2. Glyburide, Glipizide, Glimepuride
  3. Prandin, Starlix
  4. Metformin
  5. Actos, Avandia
  6. Precose, Glyset
  7. Januvia, Onglyza
  8. Isolated from the saliva of the Gila monster lizard