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Project: Ghana Emergency Medicine Collaborative
Document Title: Non-Traumatic Abdominal Pain/Abdominal Emergencies
Author(s): Joseph House (University of Michigan), MD 2012
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1
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2
Case 1
• CC: vomiting
• HPI: 2 day old female, discharged home
yesterday from outside facility

3
Case 1
• Vitals: Temp 36.9 rectally, HR 135, RR 36,
pulse-ox 98%, wt is 3.2 kg
• PE: awake, alert, well hydrated, normal
exam
• Abd: soft, non-distended hyperactive
BS
4
Case 1

Source unknown

5
Case 1

Source unknown

6
Case 1

Source unknown

7
Source unknown

8
Source unknown

9
Vomit
DDx

Source unknown

10
Most Common Cause Vomiting
• Newborn (birth to
2wks)
–
–
–
–
–

Nml “spitting up”
GERD
Obstruction
NEC
Infection

• Infant (2wks to 1yr)
–
–
–
–
–
–
–

Nml “spitting up”
GERD
Obstruction
Gastroenteritis
Infection
Post-tussive
Drug OD

11
Most Common Cause
• Children (>1yr)
– GI Obstruction
– Other GI cause
– Infection
– Post-tussive
– Metabolic
– Toxins/Drugs
– Pregnancy

12
Life Threatening
•
•
•
•

Anatomic abn
NEC
Neurologic
Renal

• Infections
• Metabolic
• Drugs

13
Work-Up
• Based on H&P
• First few days of life: delayed passage of
meconium?
• Bilious? Suspect obstruction
• Febrile? Sepsis, meningitis
• Signs of increased ICP?

14
Malrotation

St Bartholomew's Hospital Archives & Museum, London, UK, Wellcome Images

15
Malrotation with Volvulus
•
•
•
•
•

Bilious vomiting
Can occur in utero
Distention depends on site of volvulus
May develop ischemia within hour
May have h/o intermittent abd pain, failure
to thrive
• Can have malrotation w/o volvulus
16
Treatment
• OR
• Fluids
• Electrolytes

17
Case 2
• CC: vomiting
• 2wk old
• Was feeding normally 4 days ago, but then
started having increasing frequency and
quantity of vomiting
• Non-bilious

18
Case 2

1.4 cm
Source unknown

0.384 cm

19
Pyloric Stenosis
•
•
•
•
•
•

Hypertrophy of pylorus
1 in 250 births
Male : female of 4:1
First born males highest risk
Onset 2 to 5 wks
Infant is hungry and will eat, but vomit w/in
30 min
20
Pyloric Stenosis
• Electrolytes
– Na:139 K:3.4, Cl:84, BiCarb>40, BUN:21,
Cr:0.3

• Measurements: >1.4cm length, >0.3cm
thickness
• Other studies
– Upper GI

21
Pyloric Stenosis
• Treatment
– Atropine
• Reversible disorder of muscarinic
receptors
• Start treatment 0.2mg/kg/day divided
5min prior to feeds
• When tolerated po transitioned to 2x
dose orally
• Average length of treatment 52 days
– OR
22
Case 3
• CC: abdominal pain
• 9yo male
• History of abdominal migraines

23
Case 3

Source unknown

24
2yo same diagnosis

Source unknown

25
2yo same diagnosis

Source unknown

26
2yo same diagnosis

Source unknown

27
2yo same diagnosis

Source unknown

28
Intussusception
•
•
•
•

Leading cause of obstruction in infants
Most commonly between 3 and 12 months
Can have ileo-colic, ileo-ileo, or colo-colic
Small bowel prolapses through ileo-cecal
valve
• May have lead point

29
Intussusception
• COLICKY pain
• May have currant jelly stool 50-75% have
heme + stool

30
Intussusception
• Work-up
– X-ray
• Early may be normal
• After 6 to 8hrs, may show obstructive pattern

– U/S 98-100% sensitivity

31
Intussusception
• Treatment
– Air enema
• Perf rate up to 3%
• Lower success rate and higher perf rate: <3 months
or >5yrs, >48hrs of symptoms, hematochezia,
dehydration, SBO

– OR

32
Intussusception
• Antibiotics prior to reduction?
– Have heard prior peds surgeon requested it
– Only reference can find is use if suspect
peritonitis

• Surgeon needs to evaluate prior to
reduction?

33
• Recurrence
– 1 to 3%
– Can retry air enema
– More common in older
– May have lead point

34
Case 4
• CC: Abdominal pain
• 3yo male
• Pain, vomiting, constipation x3d

35
Case 4
•
•
•
•

VS: HR 148, RR 22, T 36.7, wt 16.1kg
Gen: mildly ill appearing
HEENT, Neck, CV, Resp: neg
Abd: tense, distended, tympanitic

36
Case 4

Source unknown

37
Case 4

Source unknown

38
Case 4
•
•
•
•
•

Peds surg consulted
Going to take to OR
Delayed decided to do conservative treatment
Became CV unstable to OR
Final diagnosis: perforated Meckel’s
Diverticulum

39
Meckel’s Diverticulum
• Remnant of embryonic yolk sac
• Omphalo-mesenteric duct connects yolk sac to
the gut and provides nutrition until the
placenta is established
• Between the 5th and 7th wk of gestation,
separates from the intestine
• Epithelium of the yolk sac develops a lining
similar to stomach
40
•
•
•
•
•

2% of population
Male to female: 2 to 1
Within 2 feet of ileo-cecal valve
2 inches long
2% develop problems

41
• Painless rectal bleeding
• Ulceration within gastric mucosa
• 50% do not have gastric mucosa

42
How do you find it?
• Accidentally
• Meckel’s Scan
– 99m technetium scan

Source unknown

43
Appendicitis
• Still most common requiring emergent surgery
• Peak incidents 12-18yrs, uncommon <5yrs,
rare <3yrs
• Perforation rates as high as 20%

44
Pediatric Appendicitis Score
Diagnostic Indicator
Cough/percussion/heel tapping tenderness
in RLQ

Score
2

Anorexia

1

Low-grade fever (99°F-101°F)
Nausea/emesis
RLQ tenderness upon light palpation
Leukocytosis

1
1
2
1

Left Shift
Migration of pain to RLQ

1
1

Source unknown

45
Source unknown

46
Results
2007; n (%)

2009; n (%)

P value

Age

11 +/- 3.8

10.9 +/- 4.1

0.9

Male

76 (59.6)

64 (64)

0.49

Pre-op CT

118 (80.8)

60 (60)

0.01

In-house CT

84 (71.2)

31 (51.7)

0.01

Outside CT

34(28.8)

29 (48.3)

0.01

US use

4 (2.7)

21 (21)

<0.001

No Imaging

26 (17.1)

22 (22)

0.34

Complex appy

27 (18.5)

25 (25)

0.16

Neg appy

10 (6.8)

11 (11)

0.25

Source unknown

47
Ultrasound
• Operator dependent: sensitivity and specificity
as high as 90%
• Limited by
– extreme tenderness and guarding
– weight?
– Excess of fatty tissue/bowel gas
– Lack of cooperation

48
Weight limited
Group 1:
Underweight

Group 2:
Normal Weight

Group 3:
Overweight

Total

Not seen

2 (9.5)

24 (29.6)

7 (35)

33 (27)

Normal

0

3 (3.7)

1 (5)

4 (3.2)

Inflamed

19 (90.5)

54 (66.7)

12 (60)

85 (69.7)

Total

21 (17.2)

81 (66.4)

20 (16.4)

122

Source unknown

49
Weight limited
Group 1:
Underweight

Group 2: Normal
Weight

Group 3:
Overweight

True pos

19

66

14

False pos

0

0

0

True neg

0

3

1

False neg

2

12

5

Accuracy (%)

90.4

85.1

80

Total

21

81

20

Source unknown

50
Don’t Forget
• Genital Exam
– Hernias
– Scrotal pain often radiates to the abdomen
– Ovarian Torsion

51
Case 5
•
•
•
•

CC: Abdominal pain, fullness, and vomiting
17 yo male
H/O constipation
+ weight loss

52
Source unknown

53
Source unknown

54
Constipation
• Defined as delayed or difficulty passing stool
for >2wks
• Functional
• Organic

55
Treatment
• Enema vs. no enema
– Single site
– 121 enrolled
– X-rays 69.4%
– Did not receive rectal 75.2%
– 33% had enema

56
• 27.3% had follow-up visit (42.4% to ED)
• 70.2% found visit helpful
– No difference if had enema, x-ray, or laxatives

• 63.4% reported child upset or very upset if
they received an enema

57
Hirschsprung’s Disease
• Parasympathetic ganglion cells of
Auerbach’s plexus are absent
• History of chronic constipation
• May not be stool without assistance
• Work-up
– Biopsy
– Barium enema
– Anorectal manometry
58

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GEMC: Non-Traumatic Abdominal Pain/Abdominal Emergencies: Resident Training

  • 1. Project: Ghana Emergency Medicine Collaborative Document Title: Non-Traumatic Abdominal Pain/Abdominal Emergencies Author(s): Joseph House (University of Michigan), MD 2012 License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution Share Alike-3.0 License: http://creativecommons.org/licenses/by-sa/3.0/ We have reviewed this material in accordance with U.S. Copyright Law and have tried to maximize your ability to use, share, and adapt it. These lectures have been modified in the process of making a publicly shareable version. The citation key on the following slide provides information about how you may share and adapt this material. Copyright holders of content included in this material should contact open.michigan@umich.edu with any questions, corrections, or clarification regarding the use of content. For more information about how to cite these materials visit http://open.umich.edu/privacy-and-terms-use. Any medical information in this material is intended to inform and educate and is not a tool for self-diagnosis or a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional. Please speak to your physician if you have questions about your medical condition. Viewer discretion is advised: Some medical content is graphic and may not be suitable for all viewers. 1
  • 2. Attribution Key for more information see: http://open.umich.edu/wiki/AttributionPolicy Use + Share + Adapt { Content the copyright holder, author, or law permits you to use, share and adapt. } Public Domain – Government: Works that are produced by the U.S. Government. (17 USC § 105) Public Domain – Expired: Works that are no longer protected due to an expired copyright term. Public Domain – Self Dedicated: Works that a copyright holder has dedicated to the public domain. Creative Commons – Zero Waiver Creative Commons – Attribution License Creative Commons – Attribution Share Alike License Creative Commons – Attribution Noncommercial License Creative Commons – Attribution Noncommercial Share Alike License GNU – Free Documentation License Make Your Own Assessment { Content Open.Michigan believes can be used, shared, and adapted because it is ineligible for copyright. } Public Domain – Ineligible: Works that are ineligible for copyright protection in the U.S. (17 USC § 102(b)) *laws in your jurisdiction may differ { Content Open.Michigan has used under a Fair Use determination. } Fair Use: Use of works that is determined to be Fair consistent with the U.S. Copyright Act. (17 USC § 107) *laws in your jurisdiction may differ Our determination DOES NOT mean that all uses of this 3rd-party content are Fair Uses and we DO NOT guarantee that your use of the content is Fair. To use this content you should do your own independent analysis to determine whether or not your use will be Fair. 2
  • 3. Case 1 • CC: vomiting • HPI: 2 day old female, discharged home yesterday from outside facility 3
  • 4. Case 1 • Vitals: Temp 36.9 rectally, HR 135, RR 36, pulse-ox 98%, wt is 3.2 kg • PE: awake, alert, well hydrated, normal exam • Abd: soft, non-distended hyperactive BS 4
  • 11. Most Common Cause Vomiting • Newborn (birth to 2wks) – – – – – Nml “spitting up” GERD Obstruction NEC Infection • Infant (2wks to 1yr) – – – – – – – Nml “spitting up” GERD Obstruction Gastroenteritis Infection Post-tussive Drug OD 11
  • 12. Most Common Cause • Children (>1yr) – GI Obstruction – Other GI cause – Infection – Post-tussive – Metabolic – Toxins/Drugs – Pregnancy 12
  • 14. Work-Up • Based on H&P • First few days of life: delayed passage of meconium? • Bilious? Suspect obstruction • Febrile? Sepsis, meningitis • Signs of increased ICP? 14
  • 15. Malrotation St Bartholomew's Hospital Archives & Museum, London, UK, Wellcome Images 15
  • 16. Malrotation with Volvulus • • • • • Bilious vomiting Can occur in utero Distention depends on site of volvulus May develop ischemia within hour May have h/o intermittent abd pain, failure to thrive • Can have malrotation w/o volvulus 16
  • 18. Case 2 • CC: vomiting • 2wk old • Was feeding normally 4 days ago, but then started having increasing frequency and quantity of vomiting • Non-bilious 18
  • 19. Case 2 1.4 cm Source unknown 0.384 cm 19
  • 20. Pyloric Stenosis • • • • • • Hypertrophy of pylorus 1 in 250 births Male : female of 4:1 First born males highest risk Onset 2 to 5 wks Infant is hungry and will eat, but vomit w/in 30 min 20
  • 21. Pyloric Stenosis • Electrolytes – Na:139 K:3.4, Cl:84, BiCarb>40, BUN:21, Cr:0.3 • Measurements: >1.4cm length, >0.3cm thickness • Other studies – Upper GI 21
  • 22. Pyloric Stenosis • Treatment – Atropine • Reversible disorder of muscarinic receptors • Start treatment 0.2mg/kg/day divided 5min prior to feeds • When tolerated po transitioned to 2x dose orally • Average length of treatment 52 days – OR 22
  • 23. Case 3 • CC: abdominal pain • 9yo male • History of abdominal migraines 23
  • 29. Intussusception • • • • Leading cause of obstruction in infants Most commonly between 3 and 12 months Can have ileo-colic, ileo-ileo, or colo-colic Small bowel prolapses through ileo-cecal valve • May have lead point 29
  • 30. Intussusception • COLICKY pain • May have currant jelly stool 50-75% have heme + stool 30
  • 31. Intussusception • Work-up – X-ray • Early may be normal • After 6 to 8hrs, may show obstructive pattern – U/S 98-100% sensitivity 31
  • 32. Intussusception • Treatment – Air enema • Perf rate up to 3% • Lower success rate and higher perf rate: <3 months or >5yrs, >48hrs of symptoms, hematochezia, dehydration, SBO – OR 32
  • 33. Intussusception • Antibiotics prior to reduction? – Have heard prior peds surgeon requested it – Only reference can find is use if suspect peritonitis • Surgeon needs to evaluate prior to reduction? 33
  • 34. • Recurrence – 1 to 3% – Can retry air enema – More common in older – May have lead point 34
  • 35. Case 4 • CC: Abdominal pain • 3yo male • Pain, vomiting, constipation x3d 35
  • 36. Case 4 • • • • VS: HR 148, RR 22, T 36.7, wt 16.1kg Gen: mildly ill appearing HEENT, Neck, CV, Resp: neg Abd: tense, distended, tympanitic 36
  • 39. Case 4 • • • • • Peds surg consulted Going to take to OR Delayed decided to do conservative treatment Became CV unstable to OR Final diagnosis: perforated Meckel’s Diverticulum 39
  • 40. Meckel’s Diverticulum • Remnant of embryonic yolk sac • Omphalo-mesenteric duct connects yolk sac to the gut and provides nutrition until the placenta is established • Between the 5th and 7th wk of gestation, separates from the intestine • Epithelium of the yolk sac develops a lining similar to stomach 40
  • 41. • • • • • 2% of population Male to female: 2 to 1 Within 2 feet of ileo-cecal valve 2 inches long 2% develop problems 41
  • 42. • Painless rectal bleeding • Ulceration within gastric mucosa • 50% do not have gastric mucosa 42
  • 43. How do you find it? • Accidentally • Meckel’s Scan – 99m technetium scan Source unknown 43
  • 44. Appendicitis • Still most common requiring emergent surgery • Peak incidents 12-18yrs, uncommon <5yrs, rare <3yrs • Perforation rates as high as 20% 44
  • 45. Pediatric Appendicitis Score Diagnostic Indicator Cough/percussion/heel tapping tenderness in RLQ Score 2 Anorexia 1 Low-grade fever (99°F-101°F) Nausea/emesis RLQ tenderness upon light palpation Leukocytosis 1 1 2 1 Left Shift Migration of pain to RLQ 1 1 Source unknown 45
  • 47. Results 2007; n (%) 2009; n (%) P value Age 11 +/- 3.8 10.9 +/- 4.1 0.9 Male 76 (59.6) 64 (64) 0.49 Pre-op CT 118 (80.8) 60 (60) 0.01 In-house CT 84 (71.2) 31 (51.7) 0.01 Outside CT 34(28.8) 29 (48.3) 0.01 US use 4 (2.7) 21 (21) <0.001 No Imaging 26 (17.1) 22 (22) 0.34 Complex appy 27 (18.5) 25 (25) 0.16 Neg appy 10 (6.8) 11 (11) 0.25 Source unknown 47
  • 48. Ultrasound • Operator dependent: sensitivity and specificity as high as 90% • Limited by – extreme tenderness and guarding – weight? – Excess of fatty tissue/bowel gas – Lack of cooperation 48
  • 49. Weight limited Group 1: Underweight Group 2: Normal Weight Group 3: Overweight Total Not seen 2 (9.5) 24 (29.6) 7 (35) 33 (27) Normal 0 3 (3.7) 1 (5) 4 (3.2) Inflamed 19 (90.5) 54 (66.7) 12 (60) 85 (69.7) Total 21 (17.2) 81 (66.4) 20 (16.4) 122 Source unknown 49
  • 50. Weight limited Group 1: Underweight Group 2: Normal Weight Group 3: Overweight True pos 19 66 14 False pos 0 0 0 True neg 0 3 1 False neg 2 12 5 Accuracy (%) 90.4 85.1 80 Total 21 81 20 Source unknown 50
  • 51. Don’t Forget • Genital Exam – Hernias – Scrotal pain often radiates to the abdomen – Ovarian Torsion 51
  • 52. Case 5 • • • • CC: Abdominal pain, fullness, and vomiting 17 yo male H/O constipation + weight loss 52
  • 55. Constipation • Defined as delayed or difficulty passing stool for >2wks • Functional • Organic 55
  • 56. Treatment • Enema vs. no enema – Single site – 121 enrolled – X-rays 69.4% – Did not receive rectal 75.2% – 33% had enema 56
  • 57. • 27.3% had follow-up visit (42.4% to ED) • 70.2% found visit helpful – No difference if had enema, x-ray, or laxatives • 63.4% reported child upset or very upset if they received an enema 57
  • 58. Hirschsprung’s Disease • Parasympathetic ganglion cells of Auerbach’s plexus are absent • History of chronic constipation • May not be stool without assistance • Work-up – Biopsy – Barium enema – Anorectal manometry 58