1. ATP ADP + P = ENERGY ATPase CP C + P When ATP is depleted Then reuses it ADP stimulates PFK because it will tell PFK to act of G-6-P, thus beginning non-oxidative metabolism (glycolosis). ATP-CP inhibits PFK because if you already have enough energy (ATP-CP) PFK is not needed to produce ATP.
2. Glucose HK G-6-P Synthetase ATP ATP PA LA Glycogen NAD + NADH+H NADH+H NAD + Cycle necessary for energy Epinephrine inhibits, increases fat metabolism G-6-P inhibits HK because you do not need glucose when you have an abundance of G-6-P Non-oxidative/ Anaerobic PFK Phosphorylase a Phosphorylase b Ca + , Epinephrine (adrenaline) Epinephrine stimulates phosphorylase because it is needed to send the epinephrine back to G-6-P and through PFK into the cycle to generate ATP. Ca + stimulates phosphorylase because calcium is needed to produce glycogen, which is needed by phophorylase.
4. Excessive LA Decrease in pH Enzymes and muscular properties don’t work “ heavy feeling” Slow down Cytoplasm PA LA (OXIDATIVE)
5. Mitochondria Acetyl CoA ATP ATP CO 2 CO 2 Kreb’s Cycle Electron Transport Chain H H H H H H H H H H H H H H 32 ATP molecules O 2 + H H 2 O (OXIDATIVE) Citric Acid inhibits PFK because Kreb’s Cycle produces ATP, therefore PFK is not needed to produce ATP. O 2 inhibits PFK because if you don’t have enough oxygen, then LA builds up, which will cause a “heavy feeling”. Citric Acid