A Critique of the Proposed National Education Policy Reform
Industry vsacademia 20110211
1. Professional Development Lecture 4 A career in Industry vs. Academia Peter Rose [email_address] Feb 11, 2011 Professional Development Series
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4. Drug Discovery & Development Feb 11, 2011 Professional Development Series http://www.boehringer-ingelheim.com/corporate/research/drug_discovery_process/drug_discovery_process.html Cost ~ $800-900 Million Patent life: 20 years
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11. Multidisciplinary Drug Discovery Example Biological Aspects Feb 11, 2011 Professional Development Series Biological Target (enzyme, receptor, transporter) Binding affinity Selectivity Cell Permeability Active/ Passive Transport Protein Binding Absorption Distribution Metabolism Toxicity Efficacy Dose Animal Model Drug-Drug Interactions Excretion Bioavailability Cytotoxicity Cell-based assays
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20. Feb 11, 2011 Professional Development Series Discussion/Questions? Further reading: Searls DB, 2009 Ten Simple Rules for Choosing between Industry and Academia. PLoS Comput Biol 5(6): e1000388.