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Blood Supply of the Brain &
Spinal Cord
Dr Sarwar Hossain Khan
HMO
Department of Neurology
DMCH
Blood Supply
of CNS
Two Systems:
• Carotid System (
80% )
• Vertebrobasilar
System (20%)
Vertebrobasilar System
Vertebrobasilar System
• Upper cervical spinal cord
• Brainstem and Cerebellum,
• most of the Thalamus
• Hypothalamus
• Posterior Medial Parietal lobes
• Medial & Inferior temporal lobes
• Occipital lobes
• Splenium of Corpus Callosum
Vertebral
Artery
Branches of 1st part of
subclavian artery
Ascends neck in the
transverse process of
upper six cervical
vertebra
Enters skull through
foramen magnum and
enters subarachnoid
space
Passes medially on
medulla oblongata
At the lower border of
pons joins vessel of the
opposite side to form
basilar artery
Branches of vertebral
artery
1. Meningeal
branch
2. Posterior
Spinal Artery
3. Anterior Spinal
Artery
4. Medullary
Arteries
5. Posterior
Inferior
Cerebellar
Artery(PICA)
Basilar
Artery
•Formed by union of
two vertebral arteries
•Ascends in a groove
on the anterior
surface of pons
•At the upper border
of pons divides into
two PCA
Branches
Pontine Arteries: supplies
pons
Labyrinthine Artery: supplies
internal ear
Anterior Inferior Cerebellar
Artery: supplies anterior and
inferior part of cerebellum
Superior Cerebellar Artery:
supplies superior surface of
cerebellum, pons, pineal
gland, superior medullary
velum
Posterior Cerebral Artery:
Posterior
Cerebral Artery
•At the level of the
midbrain the basilar
artery bifurcates to
form the two posterior
cerebral arteries.
•Curves laterally and
Backwards
• Around the
Midbrain.
•Here It is joined by
posterior
• Communicating
branch of ICA to form
the circle of Willis.
PICA
Largest branch of
Vertebral Artery
Supply
• Sup surface of
Vermis and
central nuclei of
cerebellum
• Medulla
oblongata
• Choroid plexus
of fourth
ventricle
AICA
•Passes posteriorly
and laterally
•Supply ant and inf
parts of cerebellum
and also lateral
part of Pons ,
upper part of
medullla oblongata
Blood Supply of the Spinal Cord
The spinal cord receives its arterial supply
from three small arteries:
• Two posterior spinal arteries
• One anterior spinal artery
• Longitudinally running arteries are reinforced by small
segmentally arranged arteries that arise from arteries
outside the vertebral column and enter the vertebral
canal through the intervertebral foramina. These
vessels anastomose on the surface of the cord and
send branches into the substance of the white and gray
matter.
Anterior Spinal Artery
• The anterior spinal artery is formed by the
union of two arteries, each of which arises
from the vertebral artery inside the skull. The
anterior spinal artery then descends on the
anterior surface of the spinal cord within the
anterior median fissure. Branches from the
anterior spinal artery enter the substance of
the cord and supply the anterior two-thirds of
the spinal cord.
Posterior Spinal Arteries
• The posterior spinal arteries arise either
directly from the vertebral arteries inside the
skull or indirectly from the posterior inferior
cerebellar arteries. Each artery descends on
the anterior surface of the spinal cord close to
the posterior nerve roots and gives off
branches that enter the substance of the cord.
The posterior spinal arteries supply the
posterior on third of the spinal cord.
Posterior Cerebral Artery
Posterior Cerebral Artery
• Central branches: Supplies
- part of the thalamus and
- the lentiform nucleus and
- the mid brain
- the pineal gland
- the medial geniculate bodies
Contd…
• Cortical branches:
1. Posterior branches to the lateral and medial
surfaces of occipital lobe, Optic radiations and visual
cortex & Splenium of the corpus callosum
2. Anterior branches to the inferolateral and
medial.surfaces of temporal lobe, Hippocampal
formation and the posterior fornix ( new declarative
memories)
3. Choroidal branches: supplies choroid plexus of
lateral and third ventricle
Carotid System
Cont..
–External Carotid Artery (ECA)
- Supply blood to facial muscles, forehead
and oral, nasal cavities.
Internal Carotid
Artery (ICA)
•- begins at the
bifurcation of CCA
• - ascends neck
• - perforates base
of the skull by passing
through the carotid
canal of temporal bone
• - runs horizontally
forward through
cavernous sinus
• - enters into sub-
arachnoid space
• - turns posteriorly
to the medial end of
lateral sulcus to divide
into ACA and MCA
Branches
Choroidal Artery-supplies-
1) crus cerebri
2) lateral geniculate
body
3) optic tract
4) parts of internal capsule
Ophthalmic Artery-
supplies-
1) eye
2) orbital structures
3) frontal area of scalp
4) ethmoid and frontal sinuses
5) dorsum of nose
Posterior
Communicating
Anterior Cerebral
Artery-
Middle cerebral Artery-
Anterior Cerebral
Artery
Smaller Terminal Branch of
ICA.
• Runs Superior to optic
nerve and
enter the longitudinal
fissure of
the cerebrum.
• Here it is Joined to anterior
cerebral artery of opposite
side
by A. com artery
• It then Curves backward
over the
Corpus Callosum &
anastomose
with PCA
Cont..
ACA
• Penetrating Branches
(Central Branches)
1) Part of Lentiform
nucleus
2) Caudate nucleus
3) Part of Internal Capsule
• Cortical Branches
1) Orbital and medial
surfaces of frontal and
parietal lobes up to
parieto- occipital
sulcus.
2) Strip of Cortex about 1
inch
3) Para central Lobule( Area
below Knee and
Control of Anal &
bladder Sphincter)
Middle cerebral
Artery
Largest Branch of ICA. Runs
in the lateral Sulcus
The Initial part of the MCA
is called the Stem
As it Passes Laterally, the
Stem gives off series of 6-
12 small diameter
Penetrating Vessels
(lenticulostriate arteries).
Then It Passes to the
Lateral Surface of the
Cerebral Hemisphere and
Gives of Cortical Superior
and Inferior Branch.
MCA
Cont
MCA
Lenticulostriate/Centr
al branches –
arises from the stem of the
MCA .
It supplies
- Part of the lentifornuclei
- Caudate nuclei and
- Part of internal capsule.
MCA
• Superior Division:
- Contra lateral
hemiplegia with
significant inv of the
upper limb
- Deviation of Eye
towards the side of the
lesion
- Broca’s Aphasia or
Motor Aphasia
• Inferior Division:
- Wernicke’s or sensory
Aphasia
- Superior quadrantic
hemianopia
- Visual neglect
- Apraxia (refers to the
inability to perform a
previously learned task
despite preserved
strength, vision, and
coordination)
Cortical Blood Supply
Cortical Blood Supply
Circle of
Willis
Lies in the
interpeduncular fossa at
the base of the brain
Formed by anastomosis
between two ICA and
two vertebral arteries
The A.com artery, ACA,
PCA, P.com artery and
Basilar artery contribute
Allows blood to be
distributed to any part
of both cerebral
hemispheres.
Blood Supply of
Brain stem
The brain stem
(Medulla, Pons &
Midbrain) receives
its blood supply
from the
vertebrobasilar
system.
Vertebral & Basilar
artery are the two
main arteires of
the brainstem.
Cont…
1. Para median
branches: Supplies
Medial parts of the
Brainstem. These are
long slender penetrating
branch. They are at risk
for hypertensive
damage, particularly in
the Pons.
2. Circumferential
branches: Dorsolateral
parts of the brainstem
are supplied by direct
circumferential
branches of either
vertebral or basilar
arteries
Blood Supply of
Medulla
1. Anterior spinal artery:
supplies to the
paramedian region of the
caudal medulla.
2. Posterior spinal artery:
supplies rostral areas,
including the gracile and
cuneate fasiculi and
nuclei & dorsal areas of
the inferior cerebellar
peduncle.
3. Vertebral artery: bulbar
branches supply areas of
both the caudal and
rostral medulla.
4. Posterior inferior
cerebellar artery:
supplies lateral medullary
areas.
Blood Supply to
the Pons
1. The Basilar artery-
Contributions of this main
artery can be subdivided
a. Paramedian
branches: to medial Pontine
region
b. Short
circumferential branches:
supply anterolateral
pons
c. Long circumferential
branches: run over the
anterior
surface of the Pons to
anastomose with AICA.
2. Some reinforcing
contributions by the anterior
inferior cerebellar and superior
cerebellar arteries
Blood Supply of Midbrain
• The major blood supply to the midbrain is
derived
mainly from branches of the Basilar Artery:
1. Posterior cerebral artery: forms a plexus
in the interpeduncular fossa, branches from this
plexus supply a wide area if the midbrain
2. Superior cerebellar artery: supplies
dorsal areas around the central gray and inferior
colliculus.
3. Posterior communicating artery
Blood Supply of
Cerebellum
1. Superior Cerebellar Artery-
Superior surface of the
cerebellum.
2. Anterior Inferior
Cerebellar Artery-
Anterior part of inferior
surface.
3. Posterior Inferior
Cerebellar Artery-
posterior part of inferior
surface.
4. The superior, middle and
inferior peduncles are
supplied by SCA, AICA &
PICA respectively.
Veins of brain
• Thin walled
• No muscular tissue in their wall
• No valves
• Lie in the subarachnoid space
• Drain into cranial venous sinuses
• Two groups: External cerebral veins and
internal cerebral veins
External Cerebral Veins
• Superior cerebral veins: pass upward over lateral
surface to empty into superior sagittal sinus
• Superficial middle cerebral vein: drains lateral
surface, runs lateral sulcus to empty into cavernous sinus
• Deep middle cerebral vein: drains insula.
Joined by anterior cerebral vein and striate veins to form
basal vein which joins great cerebral vein to drain into
straight sinus
Internal Cerebral Veins
• Two in number
• Formed by union of thalamostriate vein and
choroid vein
• Runs posteriorly and unite beneath splenium
of corpus callosum to form great cerebral vein
• Ultimately drains into straight sinus
Veins of the Spinal Cord
• The veins of the spinal cord drain into six
tortuous longitudinal channels that
communicate superiority within the skull with
veins of the brain and venous sinuses. They
drain mainly into the internal vertebral venous
plexus.
Blood supply of the brain & spinal cord by dr sarwar
Blood supply of the brain & spinal cord by dr sarwar
Blood supply of the brain & spinal cord by dr sarwar
Blood supply of the brain & spinal cord by dr sarwar

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Blood supply of the brain & spinal cord by dr sarwar

  • 1. Blood Supply of the Brain & Spinal Cord Dr Sarwar Hossain Khan HMO Department of Neurology DMCH
  • 2. Blood Supply of CNS Two Systems: • Carotid System ( 80% ) • Vertebrobasilar System (20%)
  • 4.
  • 5. Vertebrobasilar System • Upper cervical spinal cord • Brainstem and Cerebellum, • most of the Thalamus • Hypothalamus • Posterior Medial Parietal lobes • Medial & Inferior temporal lobes • Occipital lobes • Splenium of Corpus Callosum
  • 6. Vertebral Artery Branches of 1st part of subclavian artery Ascends neck in the transverse process of upper six cervical vertebra Enters skull through foramen magnum and enters subarachnoid space Passes medially on medulla oblongata At the lower border of pons joins vessel of the opposite side to form basilar artery
  • 7. Branches of vertebral artery 1. Meningeal branch 2. Posterior Spinal Artery 3. Anterior Spinal Artery 4. Medullary Arteries 5. Posterior Inferior Cerebellar Artery(PICA)
  • 8. Basilar Artery •Formed by union of two vertebral arteries •Ascends in a groove on the anterior surface of pons •At the upper border of pons divides into two PCA
  • 9. Branches Pontine Arteries: supplies pons Labyrinthine Artery: supplies internal ear Anterior Inferior Cerebellar Artery: supplies anterior and inferior part of cerebellum Superior Cerebellar Artery: supplies superior surface of cerebellum, pons, pineal gland, superior medullary velum Posterior Cerebral Artery:
  • 10. Posterior Cerebral Artery •At the level of the midbrain the basilar artery bifurcates to form the two posterior cerebral arteries. •Curves laterally and Backwards • Around the Midbrain. •Here It is joined by posterior • Communicating branch of ICA to form the circle of Willis.
  • 11. PICA Largest branch of Vertebral Artery Supply • Sup surface of Vermis and central nuclei of cerebellum • Medulla oblongata • Choroid plexus of fourth ventricle
  • 12. AICA •Passes posteriorly and laterally •Supply ant and inf parts of cerebellum and also lateral part of Pons , upper part of medullla oblongata
  • 13. Blood Supply of the Spinal Cord The spinal cord receives its arterial supply from three small arteries: • Two posterior spinal arteries • One anterior spinal artery • Longitudinally running arteries are reinforced by small segmentally arranged arteries that arise from arteries outside the vertebral column and enter the vertebral canal through the intervertebral foramina. These vessels anastomose on the surface of the cord and send branches into the substance of the white and gray matter.
  • 14.
  • 15. Anterior Spinal Artery • The anterior spinal artery is formed by the union of two arteries, each of which arises from the vertebral artery inside the skull. The anterior spinal artery then descends on the anterior surface of the spinal cord within the anterior median fissure. Branches from the anterior spinal artery enter the substance of the cord and supply the anterior two-thirds of the spinal cord.
  • 16. Posterior Spinal Arteries • The posterior spinal arteries arise either directly from the vertebral arteries inside the skull or indirectly from the posterior inferior cerebellar arteries. Each artery descends on the anterior surface of the spinal cord close to the posterior nerve roots and gives off branches that enter the substance of the cord. The posterior spinal arteries supply the posterior on third of the spinal cord.
  • 17.
  • 19. Posterior Cerebral Artery • Central branches: Supplies - part of the thalamus and - the lentiform nucleus and - the mid brain - the pineal gland - the medial geniculate bodies
  • 20. Contd… • Cortical branches: 1. Posterior branches to the lateral and medial surfaces of occipital lobe, Optic radiations and visual cortex & Splenium of the corpus callosum 2. Anterior branches to the inferolateral and medial.surfaces of temporal lobe, Hippocampal formation and the posterior fornix ( new declarative memories) 3. Choroidal branches: supplies choroid plexus of lateral and third ventricle
  • 22. Cont.. –External Carotid Artery (ECA) - Supply blood to facial muscles, forehead and oral, nasal cavities.
  • 23. Internal Carotid Artery (ICA) •- begins at the bifurcation of CCA • - ascends neck • - perforates base of the skull by passing through the carotid canal of temporal bone • - runs horizontally forward through cavernous sinus • - enters into sub- arachnoid space • - turns posteriorly to the medial end of lateral sulcus to divide into ACA and MCA
  • 24. Branches Choroidal Artery-supplies- 1) crus cerebri 2) lateral geniculate body 3) optic tract 4) parts of internal capsule Ophthalmic Artery- supplies- 1) eye 2) orbital structures 3) frontal area of scalp 4) ethmoid and frontal sinuses 5) dorsum of nose Posterior Communicating Anterior Cerebral Artery- Middle cerebral Artery-
  • 25. Anterior Cerebral Artery Smaller Terminal Branch of ICA. • Runs Superior to optic nerve and enter the longitudinal fissure of the cerebrum. • Here it is Joined to anterior cerebral artery of opposite side by A. com artery • It then Curves backward over the Corpus Callosum & anastomose with PCA
  • 27. ACA • Penetrating Branches (Central Branches) 1) Part of Lentiform nucleus 2) Caudate nucleus 3) Part of Internal Capsule • Cortical Branches 1) Orbital and medial surfaces of frontal and parietal lobes up to parieto- occipital sulcus. 2) Strip of Cortex about 1 inch 3) Para central Lobule( Area below Knee and Control of Anal & bladder Sphincter)
  • 28.
  • 29. Middle cerebral Artery Largest Branch of ICA. Runs in the lateral Sulcus The Initial part of the MCA is called the Stem As it Passes Laterally, the Stem gives off series of 6- 12 small diameter Penetrating Vessels (lenticulostriate arteries). Then It Passes to the Lateral Surface of the Cerebral Hemisphere and Gives of Cortical Superior and Inferior Branch.
  • 30. MCA
  • 31. Cont MCA Lenticulostriate/Centr al branches – arises from the stem of the MCA . It supplies - Part of the lentifornuclei - Caudate nuclei and - Part of internal capsule.
  • 32. MCA • Superior Division: - Contra lateral hemiplegia with significant inv of the upper limb - Deviation of Eye towards the side of the lesion - Broca’s Aphasia or Motor Aphasia • Inferior Division: - Wernicke’s or sensory Aphasia - Superior quadrantic hemianopia - Visual neglect - Apraxia (refers to the inability to perform a previously learned task despite preserved strength, vision, and coordination)
  • 35. Circle of Willis Lies in the interpeduncular fossa at the base of the brain Formed by anastomosis between two ICA and two vertebral arteries The A.com artery, ACA, PCA, P.com artery and Basilar artery contribute Allows blood to be distributed to any part of both cerebral hemispheres.
  • 36.
  • 37. Blood Supply of Brain stem The brain stem (Medulla, Pons & Midbrain) receives its blood supply from the vertebrobasilar system. Vertebral & Basilar artery are the two main arteires of the brainstem.
  • 38. Cont… 1. Para median branches: Supplies Medial parts of the Brainstem. These are long slender penetrating branch. They are at risk for hypertensive damage, particularly in the Pons. 2. Circumferential branches: Dorsolateral parts of the brainstem are supplied by direct circumferential branches of either vertebral or basilar arteries
  • 39. Blood Supply of Medulla 1. Anterior spinal artery: supplies to the paramedian region of the caudal medulla. 2. Posterior spinal artery: supplies rostral areas, including the gracile and cuneate fasiculi and nuclei & dorsal areas of the inferior cerebellar peduncle. 3. Vertebral artery: bulbar branches supply areas of both the caudal and rostral medulla. 4. Posterior inferior cerebellar artery: supplies lateral medullary areas.
  • 40. Blood Supply to the Pons 1. The Basilar artery- Contributions of this main artery can be subdivided a. Paramedian branches: to medial Pontine region b. Short circumferential branches: supply anterolateral pons c. Long circumferential branches: run over the anterior surface of the Pons to anastomose with AICA. 2. Some reinforcing contributions by the anterior inferior cerebellar and superior cerebellar arteries
  • 41. Blood Supply of Midbrain • The major blood supply to the midbrain is derived mainly from branches of the Basilar Artery: 1. Posterior cerebral artery: forms a plexus in the interpeduncular fossa, branches from this plexus supply a wide area if the midbrain 2. Superior cerebellar artery: supplies dorsal areas around the central gray and inferior colliculus. 3. Posterior communicating artery
  • 42. Blood Supply of Cerebellum 1. Superior Cerebellar Artery- Superior surface of the cerebellum. 2. Anterior Inferior Cerebellar Artery- Anterior part of inferior surface. 3. Posterior Inferior Cerebellar Artery- posterior part of inferior surface. 4. The superior, middle and inferior peduncles are supplied by SCA, AICA & PICA respectively.
  • 43.
  • 44. Veins of brain • Thin walled • No muscular tissue in their wall • No valves • Lie in the subarachnoid space • Drain into cranial venous sinuses • Two groups: External cerebral veins and internal cerebral veins
  • 45.
  • 46. External Cerebral Veins • Superior cerebral veins: pass upward over lateral surface to empty into superior sagittal sinus • Superficial middle cerebral vein: drains lateral surface, runs lateral sulcus to empty into cavernous sinus • Deep middle cerebral vein: drains insula. Joined by anterior cerebral vein and striate veins to form basal vein which joins great cerebral vein to drain into straight sinus
  • 47. Internal Cerebral Veins • Two in number • Formed by union of thalamostriate vein and choroid vein • Runs posteriorly and unite beneath splenium of corpus callosum to form great cerebral vein • Ultimately drains into straight sinus
  • 48. Veins of the Spinal Cord • The veins of the spinal cord drain into six tortuous longitudinal channels that communicate superiority within the skull with veins of the brain and venous sinuses. They drain mainly into the internal vertebral venous plexus.