The document discusses quality control of human chorionic gonadotropin (hCG), a hormone produced during pregnancy. It describes hCG's history, functions, production methods, purification processes, formulations, assays and related quality control tests to ensure the hormone's potency, purity and sterility. Some key points are that hCG can be extracted from urine of pregnant women or produced recombinantly, and its biological activity is determined using assays that measure effects on test animals.

1. QUALITY CONTROLE OF CHORIONIC GONADOTROPHIN BY S.RAVINDER REDDY ROLL NO:1008-10-885-011 M.PHARMACY 1 ST YEAR 1 ST SEM PHARMACEUTICAL ANALYSIS AND Q.A.

3. ABSTRACT Gonadotropins are hormones which target the gonads , structures involved in fertility and reproduction. In women, gonadotropins are directed at the ovaries , where they play in a role in the production of eggs and eventual ovulation , while in men, these hormones are involved in sperm production in the testes . Abnormalities in gonadotropin levels can lead to infertility, which can sometimes be treated with hormone injections . crude preparation of hCG, deriving from a concentrated sample of a culture medium obtained after the recombinant process or from a crude concentrate of urine of pregnant women , can be purified such that the resulting hCG is practically free from proteins or other contaminants contained in the crude hCG preparation.