Immunity

The Immune System Chapter 15 www.freelivedoctor.com

Defense Mechanisms ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Defense Mechanisms ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Defense Mechanisms ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Immunity ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

The Players ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

The Players ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Nonspecific Immunity ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Nonspecific Immunity: MB ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Nonspecific Immunity: cells and chemicals ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Nonspecific Immunity: cells and chemicals ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Nonspecific Immunity: cells and chemicals ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Nonspecific Immunity: cells and chemicals ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Phagocytosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Phagocytosis ,[object Object],www.freelivedoctor.com

Phagocytosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Phagocytosis ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Phagocytes Intracellular killing of microbes Regulate inflammation Extracellular killing Activation of clotting or anti-clotting Hormonal regulation Chemical secretion www.freelivedoctor.com

Natural Killer (NK) Cells ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Inflammatory Response ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Inflammatory Response ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Local Inflammation ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Local Inflammation ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Local Inflammation ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Antimicrobial Substances ,[object Object],[object Object],[object Object],www.freelivedoctor.com

Complement ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Complement Proteins ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Activated Complement Proteins Direct destruction by MAC (membrane attack complex) Vasodilation Increased capillary permeability Chemotaxis Opsinization (antibodies stimulate phagocytosis) www.freelivedoctor.com

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Complement Types www.freelivedoctor.com

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Complement Types www.freelivedoctor.com

Complement Fixation ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Complement Fixation ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Complement Fixation ,[object Object],[object Object],www.freelivedoctor.com

Complement Fragments ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Interferon ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Fever ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Nonspecific Immunity ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Adaptive (Specific) Immunity ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Adaptive (Specific) Immunity ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Adaptive (Specific) Immunity ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Adaptive (Specific) Immunity ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Antigens ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Haptens ,[object Object],[object Object],www.freelivedoctor.com

Immunoassays ,[object Object],[object Object],www.freelivedoctor.com

Lymphocytes ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Lymphocytes ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

B Lymphocytes ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Antibodies ,[object Object],[object Object],[object Object],www.freelivedoctor.com

Antibodies www.freelivedoctor.com Immunoglobulin Functions lgG Main form of antibodies in circulation: production increased after immunization; secreted during secondary response lgA Main antibody type in external secretions, such as saliva and mother’s milk lgE Responsible for allergic symptoms in immediate hypersensitivity reactions lgM Function as antigen receptors on lymphocyte surface prior to immunization; secreted during primary response lgD Function as antigen receptors on lymphocyte surface prior to immunization; other functions unknown

Antibody Structure ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Active Immunity ,[object Object],[object Object],[object Object],www.freelivedoctor.com

Active Immunity ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Clonal Selection Theory ,[object Object],[object Object],[object Object],www.freelivedoctor.com

Clonal Selection Theory ,[object Object],[object Object],www.freelivedoctor.com

Passive Immunity ,[object Object],[object Object],[object Object],www.freelivedoctor.com

Passive Immunity ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Monoclonal Antibodies ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

T Lymphocytes ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Killer (cytotoxic) T Cells ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Helper T Cells ,[object Object],[object Object],www.freelivedoctor.com

Suppressor T Cells ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Lymphokines ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Subtypes of Helper T Cells ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Major Histocompatability Complexes (MHC) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Major Histocompatability Complexes ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Major Histocompatability Complexes ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Destruction of T Lymphocytes ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Tumor Immunology ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Immunotherapy for Cancer ,[object Object],[object Object],[object Object],www.freelivedoctor.com

Diseases Caused by the Immune System ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Autoimmunity ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Immune Complex Diseases ,[object Object],[object Object],[object Object],www.freelivedoctor.com

Immediate Hypersensitivity ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Immunity

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