Renal pathology..at glance

RENAL PATHOLOGY ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

1. Renal Vein 2. Renal Artery 3. Renal Calyx 4. Medullary Pyramid 5. Renal Cortex 6. Segmental Artery 7. InterlobAR Artery 8. Arcuate Artery  interlobULAR 9. Arcuate Vein 10. Interlobar Vein 11. Segmental Vein 12. Renal Column 13. Renal Papillae 14. Renal Pelvis 15. Ureter www.freelivedoctor.com

S.E.M. T.E.M. www.freelivedoctor.com

Fluid and Electrolytes: Dehydration, Edema, Hyperkalemia, Metabolic acidosis Calcium Phosphate and Bone: Hyperphosphatemia, Hypocalcemia, Secondary hyperparathyroidism, Renal osteodystrophy Hematologic: Anemia, Bleeding diathesis Cardiopulmonary: Hypertension, Congestive heart failure, Pulmonary edema, Uremic pericarditis Gastrointestinal: Nausea and vomiting, Bleeding, Esophagitis, gastritis, colitis Neuromuscular: Myopathy, Peripheral neuropathy, Encephalopathy Dermatologic: Sallow (greenish-yellow) color, Pruritus, Dermatitis CHRONIC RENAL FAILURE www.freelivedoctor.com

CONGENITAL ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

AGENESIS www.freelivedoctor.com

HYPOPLASIA www.freelivedoctor.com

ECTOPIC (usually PELVIC) www.freelivedoctor.com

HORSESHOE www.freelivedoctor.com

CYSTIC DISEASES ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

CYSTIC RENAL “DYSPLASIA” ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

A UTOSOMAL D OMINANT ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

A UTOSOMAL R ECESSIVE ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

MEDULLARY CYSTS ,[object Object],[object Object],www.freelivedoctor.com

ACQUIRED (DIALYSIS) www.freelivedoctor.com

“ SIMPLE” CYSTS ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

GLOMERULAR DISEASES www.freelivedoctor.com

CLINICAL MANIFESTATIONS ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

PATHOLOGIC MANIFESTATIONS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

PATHOGENESIS ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

MEDIATORS ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

ACUTE GLOMERULONEPHRITIS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

RAPIDLY PROGRESSIVE GLOMERULONEPHRITIS ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

NEPHROTIC SYNDROME ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

MEMBRANOUS GLOMERULONEPHRITIS ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

MINIMAL CHANGE GLOM. (LIPOID NEPHROSIS) ,[object Object],[object Object],www.freelivedoctor.com

FOCAL SEGMENTAL GLOMERULO-SCLEROSIS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

IgA NEPHROPATHY (BERGER DISEASE) ,[object Object],[object Object],[object Object],www.freelivedoctor.com

HEREDITARY HEMATURIA SYNDROMES ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

CHRONIC GLOMERULONEPHRITIS ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

SECONDARY (2 º) GLUMERULONEPHROPATHIES ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

TUBULES INTERSTITIUM BLOOD VESSELS OBSTRUCTION TUMORS www.freelivedoctor.com

TUBULAR DISEASES ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

ACUTE TUBULAR NECROSIS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

ATN PATHOGENESIS ,[object Object],[object Object],www.freelivedoctor.com

CLINICAL COURSE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

TUBULO/INTERSTITIAL NEPHRITIS ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

PYELONEPHRITIS ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

ACUTE or CHRONIC PYELONEPHRITIS? www.freelivedoctor.com

FACTORS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

DRUGS/TOXINS causing INTERSTITIAL NEPHRITIS ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

ANALGESIC NEPHROPATHY ,[object Object],[object Object],[object Object],www.freelivedoctor.com

URATE NEPHROPATHY ,[object Object],H & E alcohol fixed POLARIZED LIGHT MICROSCOPY www.freelivedoctor.com

HYPERCALCEMIA NEPHROCALCINOSIS PRINCIPLE: In extreme or uncontrolled or chronic HYPERCALCEMIA, calcium stones form in the tubulo-interstitium of the kidney, which can eventually lead to tubular obstruction and loss of function www.freelivedoctor.com

MULTIPLE MYELOMA ,[object Object],[object Object],www.freelivedoctor.com

VASCULAR DISEASES ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

BENIGN NEPHROSCLEROSIS ,[object Object],[object Object],[object Object],www.freelivedoctor.com

MALIGNANT NEPHROSCLEROSIS (i.e., malignant hypertension) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Renal Artery Stenosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

PLAQUE , i.e., ATHEROSCLEROSIS FIBROMUSCULAR DYSPLASIA www.freelivedoctor.com

MICROANGIOPATHIES (thrombotic) ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

MICROANGIOPATHIES ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

OTHER VASCULAR ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

RENAL INFARCTS ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

OBSTRUCTIONS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

UROLITHIASIS ,[object Object],[object Object],[object Object],CA ↑↑↑ Bact. U.A. ↑↑↑ www.freelivedoctor.com

TUMORS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

RENAL CELL CARCINOMA ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

UROTHELIAL (TRANSITIONAL) RENAL CARCINOMAS ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

Renal pathology..at glance

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