Neurogenesis is the process by which neurons are created. This process is most active during pre-natal development when neurogenesis is responsible for populating the growing brain. Neural stem cells (NSCs) are the self-renewing, multipotent cells that differentiate into the main phenotypes of the nervous system. These cell types include neurons, astrocytes, and oligodendrocytes. Neural progenitor cells (NPCs) are the progeny of stem cell division that normally undergo a limited number of replication cycles in vivo. The terms neuronal and neural also need to be defined. Technically speaking, “neuronal” means “pertaining to neurons”, and “neural” means “pertaining to nerves, which are the cordlike bundles of fibers made up of neurons.” Since both terms ultimately are descriptive of neurons, the scientific community uses the terms "neuronal" and "neural" interchangeably. The complexity of this issue is explored from a marketing perspective within this report. View Detail Report With TOC At : http://www.researchmoz.us/strategic-development-of-neural-stem-and-progenitor-cell-products-report.html

1. Strategic Development of Neural Stem & Progenitor Cell Products
Overview: Neurogenesis is the process by which neurons are created. This process is most active during
pre-natal development when neurogenesis is responsible for populating the growing brain. Neural stem cells
(NSCs) are the self-renewing, multipotent cells that differentiate into the main phenotypes of the nervous
system. These cell types include neurons, astrocytes, and oligodendrocytes. Neural progenitor cells (NPCs) are
the progeny of stem cell division that normally undergo a limited number of replication cycles in vivo.
The terms neuronal and neural also need to be defined. Technically speaking, “neuronal”
means “pertaining to neurons”, and “neural” means “pertaining to nerves,
which are the cordlike bundles of fibers made up of neurons.” Since both terms ultimately are
descriptive of neurons, the scientific community uses the terms "neuronal" and "neural" interchangeably. The
complexity of this issue is explored from a marketing perspective within this report.
In 1992, Reynolds and Weiss were the first to isolate neural stem cells from the striatal tissue of adult mice
brain tissue, including the subventricular zone, which is a neurogenic area. Since then, neural progenitor and
stem cells have been isolated from various areas of the adult brain, including non-neurogenic areas like the
spinal cord, and from other species, including humans. During the development of the nervous system, neural
progenitor cells can either stay in the pool of proliferating undifferentiated cells or exit the cell cycle and
differentiate.
Over the past few years, neuronal stem and progenitor cells have become of profound interest to the research
community due to their potential to be used in drug discovery and delivery applications, as well as for tools of
neural toxicology assessment. NSC transplantation also represents a ground-breaking approach for treating a
range of chronic neurological diseases and acute CNS injuries, including Parkinson's, Alzheimer's and spinal
cord injury, among other conditions.
This market report focuses on recent advances in NSC research applications, explores research priorities by
market segment, highlights individual labs and end-users of neuronal stem cell research products, explores the
competitive environment for NSC research products, and provides 5-year growth and trend analysis. It
provides detailed guidance for companies that wish to offer strategically positioned NSC research products,
including cells, kits, assays, and related media and reagents.
This market report includes:
Recent advances in NSC research applications Research priorities by market segment Competitive analysis
of NSC research supply companies Segmentation of existing NSC products Individual labs and end-users of
NSC research products Patent analysis Overview of specialty pharmaceutical companies developing NSC
therapies 5-year market growth projections and trend analysis Detailed guidance for companies that wish to
offer strategically positioned NSC research products, including cells, kits, assays, media and reagents
table Of Content
i. Background
a. Neuronal Stem & Progenitor Cells
b. Language Surrounding Neuronal Stem & Progenitor Cells
Strategic Development of Neural Stem & Progenitor Cell Products

2. c. Regulation Of Neuronal Stem & Progenitor Cells
d. Brief Product Background
ii. Applications
a. Basic Research
1. Developmental Biology
2. Adult Biology
b. Drug Discovery Applications
c. Drug Delivery Applications
d. Neural Toxicology Assessment
e. Neural Transplantation
f. Brain Tumor Research
iii. Application Priorities
a. Overall
1. Cell-based Therapies: Greatest Shared Priority Across Research Community
2. Standardized Neural Toxicology Assays: Deserve Proportionally More Attention
b. Breakdown Of Neuronal Stem/progenitor Cell Therapy, By Disorder
parkinson's
brain Tumor / Glioma
stroke
spinal Cord Injury
alzheimer's
other
huntington's
multiple Sclerosis (ms)
epilepsy
amyotrophic Lateral Sclerosis (als)
schizophrenia
cerebral Palsy
c. By Segment
1. Academic
2. Biotech
3. Pharma
iv. Patents
a. Key U.s. Neuronal Stem And Progenitor Cell Patents
b. Additional U.s. Patents
c. Additional European Patents
Strategic Development of Neural Stem & Progenitor Cell Products

3. v. Projected 5-year Market Growth
a. Scientific Publication Analysis
1. Neural Vs. Neuronal Products
2. Stem Vs. Progenitor Cell Products
3. Five-year Growth Projections
4. Conclusions From Data
b. Grant Rate Analysis
1. Neural Vs. Neuronal Products
2. Stem Vs. Progenitor Cell Products
3. Five-year Growth Projections
4. Conclusions From Data
c. Patent Analysis
1. Neural Vs. Neuronal Products
2. Stem Vs. Progenitor Cell Products
3. Five-year Growth Projections
4. Conclusions From Data
vi. Competitors: Suppliers Of Neuronal Stem & Progenitor Cell Products, Including Products Offered
a. Millipore, Inc.
b. Stem Cell Technologies
c. Alphagenix, Inc.
d. R&d Systems
e. Cell Applications
f. Sa Biosciences
g. Sciencell
h. Neuromics
i. Amaxa
j. Invitrogen
k. Sigma Aldrich
l. Orion (no Longer In Existence)
vii. Specialty Pharmaceutical Companies: Neuronal Stem & Progenitor Cell Therapies
a. Neuralstem, Inc
b. Neuronova Ab
c. Neurogeneration
viii. Breakdown Of Stem Cell Research Activity By Cell Type
embryonic Scs
hematopoietic Scs
mesenchymal Scs
Strategic Development of Neural Stem & Progenitor Cell Products

4. neural Stem & Progenitor Cells
umbilical Cord Scs
cancer Scs
other Scs
fetal Scs
ix. Potential Labs/customers
a. Academic Labs
b. Private Labs
c. Commercial Labs
d. Government Labs
x. Product Ideas & Suggestions
a. Product Categories
1. Cells & Tissue
a. Fetal-derived Neural Stem Cells
b. Adult-derived Neural Stem Cells
c. Fetal-derived Immortalized Neural Stem Cells
d. Cryopreserved Embryonic Neurospheres
e. Embryonic Stem Cell Derived Neural Progenitors
f. Embryonic Primary Neuronal Tissue
g. Nsc Differentiated Progeny Cells
2. Kits
a. Kits For Analysis Of Nsc Differentiated Progeny
b. Stem Cell Functional Kits
c. Neuronal Stem Cell Phenotyping Kits
d. Neural Stem Cell Expansion Kits
e. Neural Stem Cell Differentiation Kits
f. Neural Stem Cell Blotting Kits
3. Media: Maintenance, Differentiation, Expansion, & Freezing Medium
4. Growth Factors
5. Markets: Markers For Neural Stem Cells & Differentiated Progeny
6. Pcr Arrays
7. Nucleofection Tools
8. Neural Toxicity Assessment
b. Product Suggestions
1. Neural Toxicity Assessment Products (an Untapped Niche)
2. Species-specific Opportunities
3. Areas Of Underdeveloped Competition
4. Nsc Derived From Novel Sources
5. Neural Rosette Cells (r-nscs)
Strategic Development of Neural Stem & Progenitor Cell Products

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Strategic Development of Neural Stem & Progenitor Cell Products