1. Trends in Therapeutic Partnering
The Trends in Therapeutic Partnering report provides the most comprehensive and in-depth insight into the 35
most popular therapeutic targets for partnering in the period 2007 to mid 2013. The report provides a detailed
understanding and analysis of the most popular therapeutic targets for partnering in the period 2007 to mid
2013. The majority of deals are discovery, preclinical and clinical stage whereby the licensee obtains a right or
an option right to license or access the licensors compounds or product candidates. These deals tend to be
multicomponent, starting with collaborative R&D, and commercialization of outcomes. One of the key
aspects of partnering is finding those companies that are potential candidates for the development and
commercialization of the next generation of therapeutic targets. A lot of resources are spent on finding
partners, identifying their interests and making contact to initiate discussions. Using this report, dealmakers
will effectively and efficiently target their partnering activities to deliver the company’s business
development objectives. Over 300 charts allow quick understanding of therapeutic partnering trends since
2007, together with insight into which companies are active in each of the thirty five leading therapeutic areas.
Understanding the flexibility of a prospective partner’s negotiated deals terms provides critical insight
into the negotiation process in terms of what you can expect to achieve during the negotiation of terms. Whilst
many smaller companies will be seeking details of the payments clauses, the devil is in the detail in terms of
how payments are triggered – contract documents provide this insight where press releases and
databases do not. The initial chapters of this report provide an orientation of therapeutic dealmaking.
Chapter 1 provides an introduction to the report, whilst
Chapter 2 provides an overview of therapeutic dealmaking since 2007, listing the top therapeutic areas for
partnering by deal frequency and deal dollars committed by partnering companies. Chapter 3 reviews
the top pharma and biotech therapeutic partnering deals of 2007-2013 according to reported deal size.
Chapter 4 provides a summary on best practice on how to submit an opportunity to
the leading therapeutic partnering companies, to ensure building of relationships and to obtain a prompt
assessment and response from the business development function of the prospective partner. Chapter 5 lists
forthcoming partnering events where valuable face to face meetings with big biotech provide a highly
effective means of obtaining interest in novel opportunities. These events are where dealmaking gets initiated
through numerous back to back meetings. The main body of the report is provided in Chapter 6. In-depth
profiles of each of the top 35 therapeutic target areas according to deal frequency during the period 2007-2013
provide everything required to assess the potential of the therapeutic area and its active partner companies.
Each profile includes a partnering activity overview, deal financials (including headline, upfront and royalties
rates, where available). Each therapeutic profile provides a listing of partnering deals for the top fifiteen most
active companies in each therapeutic area, and is accompanied by an appendix that provides a comprehensive
listing of deal records available at Current Agreements, each of which links direct to an online copy of the
actual deal record plus contract document if filed with the SEC. One of the key aspects of partnering is
conducting due diligence on a partner to determine under what terms a prospective partner agrees to a
partnering relationship. Understanding the flexibility of a prospective partners’ negiotated deals terms
provides critical insight into the negotiation process in terms of what you can expect to achieve during the
negotiation of terms. Whilst many smaller companies will be seeking details of the payments clauses, the devil
Trends in Therapeutic Partnering

2. is in the detail in terms of how payments are triggered – contract documents provide this insight where
press releases and databases do not. This data driven report contains
over 5,000 links to online copies of actual deal records at Current Agreements and contract documents, where
submitted to the Securities Exchange Commission by companies and their partners. Contract documents
provide the answers to numerous questions about a prospective partner’s flexibility on a wide range of
important issues, many of which will have a significant impact on each party’s ability to derive value
from the deal. In addition, contract documents provide the answers to numerous questions about a
prospective partner’s flexibility on a wide range of important issues, many of which will have a
significant impact on each party’s ability to derive value from the deal. In summary, the report
provides the reader with the tools necessary to understand trends in therapeutic partnering, the most active
therapeutic areas in terms of deal frequency and leading deal maker companies, and the deal terms and
structures achieved in such therapeutic partnering deals.
Trends in Therapeutic Partnering provides the reader with the following key benefits: In-depth
understanding of therapeutic partnering trends since 2007 Analysis of the top 35 therapeutic target areas for
partnering Comprehensive access to over 5,000 actual partnering deals entered into by the world’s
biopharma companies Detailed access to actual therapeutic partnering deals enter into by the leading fifty
bigpharma and bigbiotech companies Insight into the terms included in a therapeutic partnering agreement,
together with real world clause examples Understand the key deal terms companies have agreed in previous
deals Undertake due diligence to assess suitability of your proposed deal terms for partner companies
Report scope Trends in Therapeutic Partnering is intended to provide the reader with an
in-depth understanding of therapeutic partnering trends and structure of deals entered into by leading
companies worldwide. Trends in Therapeutic Partnering includes:
Trends in therapeutic dealmaking in the biopharma industry since 2007 Analysis of therapeutic partnering deal
structure Access to over 5,000 therapeutic partnering deals The top 35 therapeutic targets for partnering since
2007 The leading therapeutic partnering deals by value since 2007 Most active therapeutic partnering
dealmakers since 2007 In Trends in Therapeutic Partnering, the available
deals are listed by: Most active companies in partnering for each therapeutic area
Headline value Upfront payment Royalty rate Company A-Z Each deal title links to online deal records of
actual therapeutic partnering deals as disclosed by the deal parties. In addition, where available, records
include contract documents as submitted to the Securities Exchange Commission by companies and their
partners. The Trends in Therapeutic Partnering report provides comprehensive access to available deal
records for over 5,000 therapeutic target partnering deals. Analyzing actual contract agreements allows
assessment of the following: What are the precise rights granted or optioned? What is
actually granted by the agreement to the partner company? What exclusivity is granted? What is the payment
structure for the deal? How aresalesand payments audited? What is the deal term? How are the key terms of
the agreement defined? How are IPRs handled and owned? Who is responsible for commercialization? Who is
responsible for development, supply, and manufacture? How is confidentiality and publication managed? How
are disputes to be resolved? Under what conditions can the deal be terminated? What happens when there is a
change of ownership? What sublicensing and subcontracting provisions have been agreed? Which boilerplate
clauses does the company insist upon? Which boilerplate clauses appear to differ from partner to partner or
deal type to deal type? Which jurisdiction does the company insist upon for agreement law?
table Of Content
Trends in Therapeutic Partnering

3. executive Summary
chapter 1 – Introduction
chapter 2 – Trends In Therapeutic Dealmaking Activity
2.1. Introduction
2.2. Leading Therapy Partnering Areas
2.3. Top Therapeutic Targets For Partnering 2007-2013
chapter 3 – Leading Therapy Deals By Value
3.1. Introduction
3.2. Big Pharma Therapy Partnering
3.3. Big Biotech Therapy Partnering
chapter 4 – Submitting Opportunities To Therapeutic Target Partner Companies
4.1. How To Submit An Opportunity
4.2. Opportunity Submission Template
4.3. Sending Emails
4.4. Face To Face At Partnering Events
4.5. Online Submission Forms
chapter 5 – Forthcoming Therapeutic Partnering Events
5.1. Forthcoming Events
chapter 6 – Top 35 Therapeutic Partnering Targets
6.1. Introduction
6.2. Therapeutic Profiles
diabetes
diabetes Partnering In Numbers
top Diabetes Partnering Deals By Value
most Active Diabetes Partnering Companies
pain
pain Partnering In Numbers
top Pain Partnering Deals By Value
most Active Pain Partnering Companies
breast Cancer
breast Cancer Partnering In Numbers
top Breast Cancer Partnering Deals By Value
most Active Breast Cancer Partnering Companies
influenza
influenza Partnering In Numbers
Trends in Therapeutic Partnering

4. top Influenza Partnering Deals By Value
most Active Influenza Partnering Companies
hiv
hiv Partnering In Numbers
top Hiv Partnering Deals By Value
most Active Hiv Partnering Companies
alzheimer’s Disease
alzheimer’s Disease Partnering In Numbers
top Alzheimer’s Disease Partnering Deals By Value
most Active Alzheimer’s Disease Partnering Companies
inflammation
inflammation Partnering In Numbers
top Inflammation Partnering Deals By Value
most Active Inflammation Partnering Companies
prostate Cancer
prostate Cancer Partnering In Numbers
top Prostate Cancer Partnering Deals By Value
most Active Prostate Cancer Partnering Companies
wound Healing
wound Healing Partnering In Numbers
top Wound Healing Partnering Deals By Value
most Active Wound Healing Partnering Companies
leukemia
leukemia Partnering In Numbers
top Leukemia Partnering Deals By Value
most Active Leukemia Partnering Companies
lung Cancer
lung Cancer Partnering In Numbers
top Lung Cancer Partnering Deals By Value
most Active Lung Cancer Partnering Companies
nutrition
nutrition Partnering In Numbers
top Nutrition Partnering Deals By Value
most Active Nutrition Partnering Companies
rheumatoid Arthritis
rheumatoid Arthritis Partnering In Numbers
top Rheumatoid Arthritis Partnering Deals By Value
most Active Rheumatoid Arthritis Partnering Companies
colorectal Cancer
coloractal Cancer Partnering In Numbers
top Colorectal Cancer Partnering Deals By Value
most Active Colorectal Cancer Partnering Companies
solid Tumor
Trends in Therapeutic Partnering

5. solid Tumor Partnering In Numbers
top Solid Tumors Partnering Deals By Value
most Active Solid Tumor Partnering Companies
hepatitis C
hepatitis C Partnering In Numbers
top Hepatitis C Partnering Deals By Value
most Active Hepatitis C Partnering Companies
parkinson’s Disease
parkinson’s Disease Partnering In Numbers
top Parkinson’s Disease Partnering Deals By Value
most Active Parkinson’s Disease Partnering Companies
multiple Sclerosis
multiple Sclerosis Partnering In Numbers
top Multiple Sclerosis Partnering Deals By Value
most Active Multiple Sclerosis Partnering Companies
lymphoma
lymphoma Partnering In Numbers
top Lymphoma Partnering Deals By Value
most Active Lymphoma Partnering Companies
obesity
obesity Partnering In Numbers
top Obesity Partnering Deals By Value
most Active Obesity Partnering Companies
asthma
asthma Partnering In Numbers
top Asthma Partnering Deals By Value
most Active Asthma Partnering Companies
congestive Heart Failure
congestive Heart Failure Partnering In Numbers
top Congestive Heart Failure Partnering Deals By Value
most Active Congestive Heart Failure Partnering Companies
pancreatic Cancer
pancreatic Cancer Partnering In Numbers
top Pancreatic Cancer Partnering Deals By Value
most Active Pancreatic Cancer Partnering Companies
tuberculosis
tuberculosis Partnering In Numbers
top Tuberculosis Partnering Deals By Value
most Active Tuberculosis Partnering Companies
spinal Cord
spinal Cord Partnering In Numbers
top Spinal Cord Partnering Deals By Value
most Active Spinal Cord Partnering Companies
Trends in Therapeutic Partnering

6. melanoma
melanoma Partnering In Numbers
top Melanoma Partnering Deals By Value
most Active Melanoma Partnering Companies
stroke
stroke Partnering In Numbers
top Stroke Partnering Deals By Value
most Active Stroke Partnering Companies
ovarian Cancer
ovarian Cancer Partnering In Numbers
top Ovarian Cancer Partnering Deals By Value
most Active Ovarian Cancer Partnering Companies
malaria
malaria Partnering In Numbers
top Malaria Partnering Deals By Value
most Active Malaria Partnering Companies
brain Cancer
brain Cancer Partnering In Numbers
top Brain Cancer Partnering Deals By Value
most Active Brain Cancer Partnering Companies
schizophrenia
schizophrenia Partnering In Numbers
top Schizophrenia Partnering Deals By Value
most Active Schizophrenia Partnering Companies
allergy
allergy Partnering In Numbers
top Allergy Partnering Deals By Value
most Active Allergy Partnering Companies
hypertension
hypertension Partnering In Numbers
top Hypertension Partnering Deals By Value
most Active Hypertension Partnering Companies
osteoporosis
osteoporosis Partnering In Numbers
top Osteoporosis Partnering Deals By Value
most Active Osteoporosis Partnering Companies
chapter 7 – Resources
about Wildwood Ventures
current Partnering
current Agreements
recent Titles From Currentpartnering
Trends in Therapeutic Partnering

7. appendix
appendix 1 – Diabetes Deal Directory – Company A-z
appendix 2 – Pain Deal Directory – Company A-z
appendix 3 – Breast Cancer Deal Directory – Company A-z
appendix 4 – Influenza Deal Directory – Company A-z
appendix 5 – Hiv Deal Directory – Company A-z
appendix 6 – Alzheimer’s Disease Deal Directory – Company A-z
appendix 7 – Inflammation Deal Directory – Company A-z
appendix 8 – Prostate Cancer Deal Directory – Company A-z
appendix 9 – Wound Healing Deal Directory – Company A-z
appendix 10 – Leukemia Deal Directory – Company A-z
appendix 11 – Lung Cancer Deal Directory – Company A-z
appendix 12 – Nutrition Deal Directory – Company A-z
appendix 13 – Rheumatoid Arthritis Deal Directory – Company A-z
appendix 14 – Colorectal Cancer Deal Directory – Company A-z
appendix 15 – Solid Tumors Deal Directory – Company A-z
appendix 16 – Hepatitis C Deal Directory – Company A-z
appendix 17 – Parkinson’s Disease Deal Directory – Company A-z
appendix 18 – Multiple Sclerosis Deal Directory – Company A-z
appendix 19 – Lymphoma Deal Directory – Company A-z
appendix 20 – Obesity Deal Directory – Company A-z
appendix 21 – Asthma Deal Directory – Company A-z
appendix 22 – Congestive Heart Failure Deal Directory – Company A-z
appendix 23 – Pancreatic Cancer Deal Directory – Company A-z
appendix 24 – Tuberculosis Deal Directory – Company A-z
appendix 25 – Spinal Cord Deal Directory – Company A-z
appendix 26 – Melanoma Deal Directory – Company A-z
appendix 27 – Stroke Deal Directory – Company A-z
appendix 28 – Ovarian Cancer Deal Directory – Company A-z
appendix 29 – Malaria Deal Directory – Company A-z
appendix 30 – Brain Cancer Deal Directory – Company A-z
appendix 31 – Schizophrenia Deal Directory – Company A-z
appendix 32 – Allergy Deal Directory – Company A-z
appendix 33 – Hypertension Deal Directory – Company A-z
appendix 34 – Osteoporosis Deal Directory – Company A-z
appendix 35 – Deal Type Definitions
appendix 36 – Example Contract Document
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Trends in Therapeutic Partnering