5. (3) Kidney Functions
• Excretion of nitrogenous wastes
• Maintain water concentration of
blood
• Maintain electrolyte
concentration of blood
• Regulate blood pH (H ion levels)
6. (4) Ureter, Bladder &
Urethra Function
• Ureters = Tubes which carry filtered
“liquid waste” towards the bladder.
• Bladder = Storage tank for filtered
“liquid waste”.
• Urethra = Tube which allows filtered
“liquid waste” to exit body.
7.
8. (5) Kidneys & Blood Supply
• Kidneys use 20% of body’s blood
• Renal Artery = Entering
oxygenated blood
• Renal Vein = Exiting deox. Blood
• All blood is filtered through
nephrons.
9.
10. (6) Nephrons
• 2 Main Structures:
– Glomerulus Bundle of capillaries w/
blood to be filtered.
– Renal Tubule Tubes following
capillaries, which collect filtered contents
• Bowman’s Capsule = Portion of tubule
where initial filtration and absorption
occurs
11.
12.
13. (7) Urine Formation
• Filtration:
– Water + Small Solutes are forced through capillary
walls into Bowman’s Capsule.
• Reabsorption:
– Water, Glucose, Amino Acids & Ions that were filtered
out are actively transported back into capillaries and
blood.
• Secretion:
– H ions, K ions, urea, and drugs/toxins are forced
through capillary walls into renal tubule.
14.
15. (8) Anatomy of Urine
Formation
• Filtration Bowman’s Capsule of
Renal Tubule
• Reabsorption Proximal Tube,
Loop of Henle & Distal Tubule of
Renal Tubule
• Secretion Distal Tubule of Renal
Tubule
16.
17. (9) Nitrogenous Wastes
• Urea: Byproduct of protein
metabolism in the liver.
• Uric Acid: Byproduct of nucleic
acid metabolism.
• Creatinine: Byproduct of creatine
metabolism in muscle tissue.
18. (10) Regulating Drops in
Blood Pressure
• Antidiuretic Hormone (ADH) from Pituitary:
– Increases water reabsorption from renal tubule.
• Aldosterone from Kidney:
– Increases water retention in blood by
reabsorbing more sodium from renal tubule.
• Angiotensin II from Blood:
– Causes vasoconstriction, increasing blood
pressure
19. (11) Don’t Pee It Out…
• Glucose Chill out on sweets OR Diabetic?!
• Protein Increased Physical Activity &
Pregnancy OR Hypertension & Nephron
Disease?!
• Pus Urinary Tract Infection
• Blood Kidney Stones, Infection, Trauma,
Anemia ?!
• Bile Liver Disease?!
20. (12) Kidney Dialysis
• Used in hospitals when kidneys fail (stop working)
• Blood is filtered through mechanical pump +
tubing which regulates contents
• Causes for Kidney Failure:
– Repeated kidney infections
– Physical Trauma
– Heavy Metal / Chemical poisoning
– Low Blood delivery (arteriosclerosis)