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Chapter 9 compounding
- 1. The Pharmacy Technician 4E Chapter 9 Compounding
- 28. Graduates conical graduate cylindrical graduate correct level incorrect level reading a graduate meniscus
- 29. Small Volumetric Equipment Calibrated pipette Single volume pipettes Measure volume to edge of stopper. Syringe
- 34. Mixing Powders - Geometric Dilution When mixing powders of unequal size, the smaller amount is mixed (triturated) with an equal amount of the other. That mixture is then mixed with an equal amount of the larger amount powder. This process is repeated until the mixture is completed.
- 41. Suppositories Three types of bases: Oleaginous : primarily synthetic triglycerides. Water soluble : containing glycerinated gelatin or polethylene glycols (PEGs). Hydrophyllic : mixtures of oleaginous and water soluble bases. Mold Suppository box
- 45. Punch Method Used when filling a small number of capsules.
Notas del editor
- Usp/nf 60 chapters are pertaining to compounding
- Pg 228 star- grade of chemical and corresponding description Chromatography- used to separate mixtures (chemistry) Primary standard is the highest purity-used in standard solutions for analytical purposes
- MSDS are even located with any haz waste material- gives boiling point, what to do if spilled
- Use according to manufacturer Drug specific info/reference USP ch 795 gives max recommended beyond-use dates for nonsterile compounds see next slides
- Sensitivity-6mg sensitivity means the amount of weight that will move the balance pointer one division mark on the marker plate Aliquot –a portion of a mixture Do not handle weights with fingers Degree of error is 5%
- Do not use your hands to touch weights
- Ex prednisone with glycerin prior to putting in suspension
- TD to deliver TC to contain
- Bring in a graduate to demonstrate Meniscus is the curved surface of a column of liquid
- If just mixed together NOT homogenous
- Flocculating agents enhance particles being dispersed Increased viscosity helps reduce the sedimentation rate
- Emulsifier is stabilizing agent
- Continental method of dry gum method is one way to make emulsions pg 249
- Three kinds: oleaginous bases, water soluble or miscible, or hydrophillic
- Miscible means capable of being mixed together
- Bring in different sizes of capsules Higher the number size the smaller the volume