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Nutrition Support   Special Considerations in Neonates Sajjad Ahmad RPh. BCNSP TPN Pharmacist, In-Charge IV Admixture Services KFSH&RC Jeddah K.S.A (May 2009)
2
Defining Neonates In Terms Of Weight 3
Nutrition Support In NICU 4 Nutrition Support is applied inappropriately in NICU1 1. A.S.P.E.N Nutrition Support Practice manual 2nd edition 2005 p301
Phases of NS in critically Ill Infants 5
Special Considerations in Premature & Sick Infants 6
Nutritional Issues In NICU 7
ParenteralNutrition 8
Peripheral Route of Nutrition 9
Peripheral Solutions – Osmolarity Calculations 10
Routes of Administration - Central 11
Central Access Options HICKMAN CATHETER PORT GROSHONG PICC LINE 12
Central Solutions 13
Fluids 14
Fluids 15 ,[object Object]
 Phototherapy
 RDS
 Fever
 Diuretics
 GI losses
Glycosuria
 Heat shields
 Blankets
 Double-walled incubators
 High humidity
 Fluid overload
 Heart failureIncreased Requirements Decreased Requirements
Fluids 16
Parenteral Nutrition 17 A.S.P.E.N. Board of Directors and the Clinical Guidelines Task Force. Guidelines for the use of parenteral and enteral nutrition in adult and pediatric patients. J Parenter Enteral Nutr. 2002;26(1suppl): 1SA–138SA.
18 Parenteral Nutrition
OUTCOMES OF NUTRITION THERAPY 19
Energy Requirements components 20
TPN Initiation…do not start at goal  21
Pathogenesis of Re-feeding Syndrome 22
Pathogenesis of Re-feeding Syndrome 23
Hypophosphatemia 24
Cardiac dysfunction 25
Neuromuscular Dysfunction 26
Respiratory  Insufficiency 27
Hematologic Effects of Hypophosphatemia 28
Hypokalemia 29
Hypomagnesemia 30
Recommendations to Avoid Re-feeding 31
Parenteral Nutrition 32
33
Parenteral nutrition Protein Requirements 34
Parenteral nutrition 35
Parenteral Nutrition 36
Parenteral Nutrition Dextrose (3.4Kcalories per Gm) 37
Parenteral Nutrition 38
39 Parenteral Nutrition
40 Parenteral Nutrition
Parenteral Nutrition 41
essential fatty acid deficiency (EFAD) Deficiency of linoleic and linolenic acids Manifestations (hair loss, delay wound healing, dry scaly skin) EFAD can develop within 72 hours if exogenous fat is not given.  EFAD can be prevented with as little as 0.5–1 g/kg/d of IV lipid 42
43 Parenteral Nutrition
Parenteral Nutrition 44
Parenteral Nutrition 45
Calcium Phosphate Solubility Precipitation factor =mEq of Ca++ + mM of PO4 x 100 Vol (ml) of TPN before addition 					of Ca & Phosphate If AA Concentartion > 1.5% the precipitation factor must be < 3 If AA concentration >1 % and < 1.5%, the precipitation factor should be < 2 For PN solutions < 1% AA concentration, either calcium or phosphorous should be added Parenteral Nutrition 46
Parenteral Nutrition 47
48 Parenteral Nutrition 3. Effects of Early Erythropoietin Therapy on the Transfusion Requirements of Preterm Infants Below 1250 Grams Birth Weight A Multicenter, Randomized, Controlled Trial. Pediatrics. 2001;108:934–942.
Effects of micronutrient deficiency 49
Effects of micronutrient deficiency 50
Effects of micronutrient deficiency 51
52 Parenteral Nutrition
Monitoring 53 Parenteral Nutrition
Monitoring 54 Parenteral Nutrition
Parneteral Nutrition 55
Parenteral Nutrition 56
Parenteral Nutrition 57
Parenteral Nutrition 58
Parenteral Nutrition 59
Parenteral Nutrition 60
Cyclic TPN 61
62
Parenteral Nutrtion 63
Cause of Occlusion Thrombus Crystals Urokinase HCl 0.1N Success Failure Failure Success HCl Urokinase Success Success Failure Failure Ethanol 70% Ethanol 70% 64 Management Of Catheter Occlusion
Do’s and Don’tsParenteral Nutrition Solutions 65
66 Do’s and Don’tsParenteral Nutrition Solutions
Filtration of Parenteral Nutrition Admixtures 67
Transitioning to Enteral Feeds 68
Enteral Nutrition Special Considerations in Neonates 69
Enteral Nutrition 70
Enteral Nutrition 71
Necrotizing  Enterocolitis and Enteral Feeding 72
Necrotizing  Enterocolitis and Enteral Feeding 73
Enteral Formulations 74
Enteral Formulations 75
76 Enteral Formulations
Enteral Formulations 77

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Nutrition Support Special Considerations For Nenaotes

Notas del editor

  1. Diuretics case mineral and electrolyte losses.Corticosteroids used to shorten the ventilator support can cause negative nitrogen balance, delayed growth, glucose intolerance, bone demineralization and neurodevelopment impairment.