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Protein Digestion and Metabolism in
Poultry
Saurabh Rajvaidya
PhD Scholar, NDRI, Karnal
Digestive System of Poultry
• First site of protein
digestion
Initiation of gastric juice secreation in proventriculus
Ingestion of feed
Vagus nerve stimulation
Digestion
In low pH medium Pepsinogen get converts to pepsin
Pepsin
Proventriculus secreats HCl and Pepsinogen (Inactive)
Pepsin-2 active centres-fast degradation of protein
Effect on several different peptide linkages
Most pronounced effect is between
Leucine and valine, Tyrosine and Leucine, Phenyle alanine
and phenyle alanine and Phenyle alanine and tyrosine
• 5 types of pepsinogens have been extracted
from chicken proventriculus
Feed (Protein-
Complex form)
HCl
Heat treatment
(Expanding,
Extrusion, Cooking,
Pelleting)
Denaturation
• Feed mixed with the fluid reaches to gizzard
• Gizzard is important organ for grinding of feed
• Insoluble grit plays important role
I. Provide additional surface for grinding
II. Stimulate motility of gizzard
• Coarse feed particles(whole grains with min
Processing)-grit is important
• Feed-ground-No gizzard-No effect on digestion
Role of Gizzard in Digestion
Digestion in Small Intestine
Pancreas
Group of
Enzymes
Zymogen
(Inactive)
Trypsinogen
Trypsin
Intestinal mucosa Enterokinase
Duodenum
Elastase
Chymotrypsin
Trypsin
Lysine
and/Arginine Non specificAromatic A A
• Exopeptidase are secreated from pancreas
• Carboxypeptide A and B
• Act on terminal carboxy bond
• Remove Amino acids
• Collagenases converts collagen to small peptides
• Jejunal wall-erepsin and polynucleosidase
• Erepsin converts Small peptides to AA and
dipeptides
• Polynucleosidase converts Nucleotides to
mononucleotides
• Endopeptidases act on peptides and converts
them in small peptides (2-10 AA) or
sometimes in free Amino acids
• In lumen-peptidases-desquamated mucosal
cells and intestinal mucosa
Reaches to intestinal mucosal cells
Peptides
Sodium pump absorption
Absorption
Cell cytoplasm having enzymes
Complete hydrolysis of peptides in free amino acids
Nitrogen Pool
carbon dioxide, water,
uric acid, ATP
Transamination
• Portal system do not complete reflect Amino
acid pattern of diet because some AA are
incorporated in protein of mucosa
• In some proteins peptide absorption is more rather than
free amino acids
• Trace amount of peptides in plasma may be present
• In jejunum peptide uptake is more
• In ileum amino acid uptake is more
• L-form are rapidly absorbed than D-form
• Only D-methionine has more affinity than L
• The catabolism process (in liver) involves removal of
amino group and the resulting keto acids then it oxidized
to form energy (ATP), glucose and lipid
• Caeca is the major site for microbial protein degradation
which further degrades in amino acids and get absorbed
Transamination
• Sources of endogenous proteins
• Saliva
• Gastric juice
• Pancreatic juice
• Desquamated epithelial cells
• In Kidney tubules reabsorption of Amino acids occurs
• High level of lysine fed- More Urinary losses of Arginine
• In poultry the waste products are metabolised principally in
uric acid for excreation
Excreation
Thank you

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Protein digestion and metabolism in poultry

  • 1. Protein Digestion and Metabolism in Poultry Saurabh Rajvaidya PhD Scholar, NDRI, Karnal
  • 2. Digestive System of Poultry • First site of protein digestion
  • 3. Initiation of gastric juice secreation in proventriculus Ingestion of feed Vagus nerve stimulation Digestion In low pH medium Pepsinogen get converts to pepsin Pepsin Proventriculus secreats HCl and Pepsinogen (Inactive) Pepsin-2 active centres-fast degradation of protein Effect on several different peptide linkages Most pronounced effect is between Leucine and valine, Tyrosine and Leucine, Phenyle alanine and phenyle alanine and Phenyle alanine and tyrosine
  • 4.
  • 5. • 5 types of pepsinogens have been extracted from chicken proventriculus
  • 6. Feed (Protein- Complex form) HCl Heat treatment (Expanding, Extrusion, Cooking, Pelleting) Denaturation
  • 7. • Feed mixed with the fluid reaches to gizzard • Gizzard is important organ for grinding of feed • Insoluble grit plays important role I. Provide additional surface for grinding II. Stimulate motility of gizzard • Coarse feed particles(whole grains with min Processing)-grit is important • Feed-ground-No gizzard-No effect on digestion Role of Gizzard in Digestion
  • 8. Digestion in Small Intestine Pancreas Group of Enzymes Zymogen (Inactive) Trypsinogen Trypsin Intestinal mucosa Enterokinase
  • 10. • Exopeptidase are secreated from pancreas • Carboxypeptide A and B • Act on terminal carboxy bond • Remove Amino acids • Collagenases converts collagen to small peptides • Jejunal wall-erepsin and polynucleosidase • Erepsin converts Small peptides to AA and dipeptides • Polynucleosidase converts Nucleotides to mononucleotides
  • 11. • Endopeptidases act on peptides and converts them in small peptides (2-10 AA) or sometimes in free Amino acids • In lumen-peptidases-desquamated mucosal cells and intestinal mucosa
  • 12.
  • 13. Reaches to intestinal mucosal cells Peptides Sodium pump absorption Absorption Cell cytoplasm having enzymes Complete hydrolysis of peptides in free amino acids
  • 14.
  • 15.
  • 16. Nitrogen Pool carbon dioxide, water, uric acid, ATP
  • 18. • Portal system do not complete reflect Amino acid pattern of diet because some AA are incorporated in protein of mucosa
  • 19. • In some proteins peptide absorption is more rather than free amino acids • Trace amount of peptides in plasma may be present • In jejunum peptide uptake is more • In ileum amino acid uptake is more • L-form are rapidly absorbed than D-form • Only D-methionine has more affinity than L
  • 20. • The catabolism process (in liver) involves removal of amino group and the resulting keto acids then it oxidized to form energy (ATP), glucose and lipid • Caeca is the major site for microbial protein degradation which further degrades in amino acids and get absorbed
  • 22. • Sources of endogenous proteins • Saliva • Gastric juice • Pancreatic juice • Desquamated epithelial cells
  • 23. • In Kidney tubules reabsorption of Amino acids occurs • High level of lysine fed- More Urinary losses of Arginine • In poultry the waste products are metabolised principally in uric acid for excreation Excreation
  • 24.
  • 25.
  • 26.